Johan Vallon-christersson

Publication List Details

Period

2001 - 2009

Number

30

Co-Authors

BASE - 2nd generation software for microarray data management and analysis (2009)

Vallon-Christersson, Johan, Nordborg, Nicklas, Svensson, Martin, Häkkinen, Jari

Abstract Background Microarray experiments are increasing in size and samples are collected asynchronously over long time. Available data are re-analysed as more samples are hybridized. Systematic...

Normalization of Illumina Infinium whole-genome SNP data improves copy number estimates and allelic intensity ratios (2008)

Staaf, Johan, Vallon-Christersson, Johan, Lindgren, David, Juliusson, Gunnar, Rosenquist, Richard, Höglund, Mattias, ...

Abstract Background Illumina Infinium whole genome genotyping (WGG) arrays are increasingly being applied in cancer genomics to study gene copy number alterations and allele-specific aberrations such...

Segmentation-based detection of allelic imbalance and loss-of-heterozygosity in cancer cells using whole genome SNP arrays (2008)

Staaf, Johan, Lindgren, David, Vallon-Christersson, Johan, Isaksson, Anders, Göransson, Hanna, Juliusson, Gunnar, ...

Abstract We present a strategy for detection of loss-of-heterozygosity and allelic imbalance in cancer cells from whole genome single nucleotide polymorphism genotyping data. Using a dilution series...

Research Article Distinct Genomic Profiles in Hereditary Breast Tumors Identified by Array-Based Comparative Genomic Hybridization (2008)

Göran Jönsson, Tara L. Naylor, Johan Vallon-christersson, Johan Staaf, Jia Huang, M. Renee Ward, ...

Mutations in BRCA1 and BRCA2 account for a significant proportion of hereditary breast cancers. Earlier studies have shown that inherited and sporadic tumors progress along different somatic genetic...

Normalization of array-CGH data: influence of copy number imbalances (2007)

Staaf, Johan, Jönsson, Göran, Ringnér, Markus, Vallon-Christersson, Johan

Abstract Background High-resolution microarray-based comparative genomic hybridization (CGH) techniques have successfully been applied to study copy number imbalances in a number of settings such as...

Non-coding antisense transcription detected by conventional and single-stranded cDNA microarray (2007)

Vallon-Christersson, Johan, Staaf, Johan, Kvist, Anders, Medstrand, Patrik, Borg, Åke, Rovira, Carlos

Abstract Background Recent studies revealed that many mammalian protein-coding genes also transcribe their complementary strands. This phenomenon raises questions regarding the validity of data...

Functional and Molecular Characterization of BRCA1 and BRCA2 Associated Breast Cancer (2005)

Vallon-Christersson, Johan

This doctoral dissertation is based on five appended papers primarily concerned with three main topics, namely: the functional characterization of specific and clinically relevant perturbations found...

Calibration and assessment of channel-specific biases in microarray data with extended dynamical range (2004)

Bengtsson, Henrik, Jönsson, Göran, Vallon-Christersson, Johan

Abstract Background Non-linearities in observed log-ratios of gene expressions, also known as intensity dependent log-ratios, can often be accounted for by global biases in the two channels being...

Characterization of a novel breast carcinoma xenograft and cell line derived from a BRCA1 germ-line mutation carrier (2003)

Johannsson, Oskar T, Staff, Synnöve, Vallon-Christersson, Johan, Kytöla, Soili, Gudjonsson, Thorarinn, Rennstam, Karin, ...

A human tumor xenograft (L56Br-X1) was established from a breast cancer axillary lymph node metastasis of a 53-year-old woman with a BRCA1 germ-line nonsense mutation (1806C>T; Q563X), and a cell...

Characterization of a Novel Breast Carcinoma Xenograft and Cell Line Derived from a BRCA1 Germ-Line Mutation Carrier. (2003)

Johannsson, Oskar T, Staff, Synnöve, Vallon-Christersson, Johan, Kytöla, Soili, Gudjonsson, Thorarinn, Rennstam, Karin, ...

A human tumor xenograft (L56Br-X1) was established from a breast cancer axillary lymph node metastasis of a 53-year-old woman with a BRCA1 germ-line nonsense mutation (1806C>T; Q563X), and a cell...

BioArray Software Environment (BASE): a platform for comprehensive management and analysis of microarray data (2002)

Saal, Lao H, Troein, Carl, Vallon-Christersson, Johan, Gruvberger, Sofia, Borg, Åke, Peterson, Carsten

Abstract The microarray technique requires the organization and analysis of vast amounts of data. These data include information about the samples hybridized, the hybridization images and their...

Bioarray software environment (base): a platform for comprehensive management and analysis of microarray data (2002)

Lao H Saal, Carl Troein, Johan Vallon-christersson, Sofia Gruvberger, Åke Borg, Carsten Peterson

(Print ISSN 1465-6906; Online ISSN 1465-6914) The microarray technique requires the organization and analysis of vast amounts of data. These data include information about the samples hybridized, the...

Functional analysis of BRCA1 C-terminal missense mutations identified in breast and ovarian cancer families (2001)

Vallon-Christersson, Johan, Cayanan, Charmagne, Haraldsson, Karin, Loman, Niklas, Bergthorsson, Jon Thor, Brøndum-Nielsen, Karen, ...

Germline mutations in the breast and ovarian cancer susceptibility gene BRCA1 are responsible for the majority of cases involving hereditary breast and ovarian cancer. Whereas all truncating...

BioArray Software Environment (BASE): a platform for comprehensive management and analysis of microarray data

Saal, Lao H, Troein, Carl, Vallon-Christersson, Johan, Gruvberger, Sofia, Borg, Åke, Peterson, Carsten

The microarray technique requires the organization and analysis of vast amounts of data. These data include information about the samples hybridized, the hybridization images and their extracted data...

BioArray Software Environment (BASE): a platform for comprehensive management and analysis of microarray data

Saal, Lao H, Troein, Carl, Vallon-Christersson, Johan, Gruvberger, Sofia, Borg, Åke, Peterson, Carsten

The microarray technique requires the organization and analysis of vast amounts of data. These data include information about the samples hybridized, the hybridization images and their extracted data...

Segmentation-based detection of allelic imbalance and loss-of-heterozygosity in cancer cells using whole genome SNP arrays

Staaf, Johan, Lindgren, David, Vallon-Christersson, Johan, Isaksson, Anders, Göransson, Hanna, Juliusson, Gunnar, ...

A strategy is presented for detection of loss-of-heterozygosity and allelic imbalance in cancer cells from whole genome SNP genotyping data.