John A. Dani

Dopamine signaling differences in the nucleus accumbens and dorsal striatum exploited by nicotine (2009)

Zhang, Tianxiang, Zhang, Lifen, Liang, Yong, Siapas, Athanassios G., Zhou, Fu-Ming, Dani, John A.

The dorsal striatum and the nucleus accumbens (NAc) shell of the ventral striatum have similar cellular components and are both richly innervated by dopamine neurons. Despite similarities that extend...

Nicotinic Cholinergic Synaptic Mechanisms in the Ventral Tegmental Area Contribute to Nicotine Addiction (2004)

Pidoplichko, Volodymyr I., Noguchi, Jun, Areola, Oluwasanmi O., Liang, Yong, Peterson, Jayms, Zhang, Tianxiang, ...

Tobacco use is a major health problem that is estimated to cause 4 million deaths a year worldwide. Nicotine is the main addictive component of tobacco. It acts as an agonist to activate and...

Nicotinic Cholinergic Synaptic Mechanisms in the Ventral Tegmental Area Contribute to Nicotine Addiction

Pidoplichko, Volodymyr I., Noguchi, Jun, Areola, Oluwasanmi O., Liang, Yong, Peterson, Jayms, Zhang, Tianxiang, ...

Tobacco use is a major health problem that is estimated to cause 4 million deaths a year worldwide. Nicotine is the main addictive component of tobacco. It acts as an agonist to activate and...

Acetylcholine-Activated Channel Current-Voltage Relations in Symmetrical Na+ Solutions

Dani, John A., Eisenman, George

Nicotinic Cholinergic Synaptic Mechanisms in the Ventral Tegmental Area Contribute to Nicotine Addiction

Pidoplichko, Volodymyr I., Noguchi, Jun, Areola, Oluwasanmi O., Liang, Yong, Peterson, Jayms, Zhang, Tianxiang, ...

Tobacco use is a major health problem that is estimated to cause 4 million deaths a year worldwide. Nicotine is the main addictive component of tobacco. It acts as an agonist to activate and...

Acetylcholine-Activated Channel Current-Voltage Relations in Symmetrical Na+ Solutions

Dani, John A., Eisenman, George

Acid-sensitive ionic channels in midbrain dopamine neurons are sensitive to ammonium, which may contribute to hyperammonemia damage

Pidoplichko, Volodymyr I., Dani, John A.

Acid-sensitive ion channels (ASICs) are proton-gated and belong to the family of degenerin channels. In the mammalian nervous system, ASICs are most well known in sensory neurons, where they are...

Regulation of the sensitivity of acetylcholine receptors to nicotine in rat habenula neurons

Hicks, John H, Dani, John A, Lester, Robin A J

Time-dependent changes in nicotinic acetylcholine receptor (nAChR) function were studied in acutely isolated medial habenula neurons during whole-cell perfusion.The peak amplitude of inward currents...

Mouse muscle denervation increases expression of an α7 nicotinic receptor with unusual pharmacology

Tsuneki, Hiroshi, Salas, Ramiro, Dani, John A

Neuronal nicotinic α7 subunits have been found in chick and rat skeletal muscle during development and denervation. In the present study, reverse transcriptase-polymerase chain reaction was used to...