Scientific Commons: John A. Tine

Microarray analysis in B cells among siblings with/without MS - role for transcription factor TCF2 (2008)

Avasarala, Jagannadha R, Chittur, Sridar V, George, Ajish D, Tine, John A

Abstract Background We investigated if global gene expression and transcription networks in B-lymphocytes of siblings with multiple sclerosis (MS) were different from healthy siblings. Results Using...

Evolution of the Q region :--a study of the diversity of Qa-2 and Qa-2-determining genes in wild mice /--by John A. Tine. (1989)

Tine, John A.

Photocopy of typescript.

Boosting with recombinant vaccinia increases immunogenicity and protective efficacy of malaria DNA vaccine

Sedegah, Martha, Jones, Trevor R., Kaur, Manjit, Hedstrom, Richard, Hobart, Peter, Tine, John A., ...

To enhance the efficacy of DNA malaria vaccines, we evaluated the effect on protection of immunizing with various combinations of DNA, recombinant vaccinia virus, and a synthetic peptide....

Multistage Multiantigen Heterologous Prime Boost Vaccine for Plasmodium knowlesi Malaria Provides Partial Protection in Rhesus Macaques

Rogers, William O., Baird, J. Kevin, Kumar, Anita, Tine, John A., Weiss, Walter, Aguiar, João C., ...

A nonhuman primate model for malaria vaccine development allowing reliable, stringent sporozoite challenge and evaluation of both cellular and antibody responses is needed. We therefore constructed a...

Protection of Rhesus Macaques against Lethal Plasmodium knowlesi Malaria by a Heterologous DNA Priming and Poxvirus Boosting Immunization Regimen

Rogers, William O., Weiss, Walter R., Kumar, Anita, Aguiar, João C., Tine, John A., Gwadz, Robert, ...

We tested a cytokine-enhanced, multiantigen, DNA priming and poxvirus boosting vaccine regimen for prevention of malaria in the Plasmodium knowlesi-rhesus macaque model system. Animals were primed...