John D. C. Lambert

Characteristics of AMPA receptor-mediated responses of cultured cortical and spinal cord neurones and their correlation to the expression of glutamate receptor subunits, GluR1-4

Dai, Wei-Min, Egebjerg, Jan, Lambert, John D C

Electrophysiological recordings have been used to characterize responses mediated by AMPA receptors expressed by cultured rat cortical and spinal cord neurones. The EC50 values for AMPA were 17 and...

Factors determining the efficacy of distal excitatory synapses in rat hippocampal CA1 pyramidal neurones

Andreasen, Mogens, Lambert, John D C

A new preparation of the in vitro rat hippocampal slice has been developed in which the synaptic input to the distal apical dendrites of CA1 pyramidal neurones is isolated. This has been used to...

Post-tetanic potentiation of GABAergic IPSCs in cultured rat hippocampal neurones

Jensen, Kimmo, Jensen, Morten Skovgaard, Lambert, John D C

Dual whole-cell patch-clamp recording was used to investigate post-tetanic potentiation (PTP) of GABAergic IPSCs evoked between pairs of cultured rat hippocampal neurones. Tetanization of the...

Somatic amplification of distally generated subthreshold EPSPs in rat hippocampal pyramidal neurones

Andreasen, Mogens, Lambert, John D C

Intracellular recordings from hippocampal CA1 pyramidal neurones revealed that EPSPs evoked by selective stimulation of the isolated afferent input to the distal third of the apical dendrites were...