John D. Clemens

Polish metric spaces: their classification and isometry groups (2007)

John D. Clemens, Su Gao, S. Kechris

Introduction. In this communication we present some recent results on the classification of Polish metric spaces up to isometry and on the isometry groups of Polish metric spaces. A Polish metric...

Controlling Endemic Cholera with Oral Vaccines (2007)

Ira M. Longini Jr., Azhar Nizam, Mohammad Ali, Mohammad Yunus, Neeta Shenvi, John D. Clemens

BackgroundAlthough advances in rehydration therapy have made cholera a treatable disease with low case-fatality in settings with appropriate medical care, cholera continues to impose considerable...

Comparisons of predictors for typhoid and paratyphoid fever in Kolkata, India (2007)

Sur, Dipika, Ali, Mohammad, Von Seidlein, Lorenz, Manna, Byomkesh, Deen, Jacqueline L, Acosta, Camilo J, ...

Abstract Background: Exposure of the individual to contaminated food or water correlates closely with the risk for enteric fever. Since public health interventions such as water improvement or...

Spatial risk for gender-specific adult mortality in an area of southern China (2007)

Ali, Mohammad, Jin, Yang, Kim, Deok, De, Zhou, Park, Jin, Ochiai, Rion, ...

Abstract Background Although economic reforms have brought significant benefits, including improved health care to many Chinese people, accessibility to improved care has not been distributed evenly...

Contents (2007)

Andrés Eduardo Caicedo, John D. Clemens, Clinton Conley, Benjamin D. Miller

We show that if X is a set and A is a non-empty family of n-element subsets of X that does not contain a pairwise disjoint family of cardinality strictly greater than k, then a non-empty subset of X...

Lessons and implications from a mass immunization campaign in squatter settlements of Karachi, Pakistan: an experience from a cluster-randomized double-blinded vaccine trial [NCT00125047] (2006)

Khan, Mohammad, Ochiai, Rion, Hamza, Hasan, Sahito, Shah, Habib, Muhammad, Soofi, Sajid, ...

Abstract Objective To determine the safety and logistic feasibility of a mass immunization strategy outside the local immunization program in the pediatric population of urban squatter settlements in...

A hospital-based surveillance for Japanese encephalitis in Bali, Indonesia (2006)

Kari, Komang, Liu, Wei, Gautama, Kompiang, Mammen, Mammen P, Clemens, John D, Nisalak, Ananda, ...

Abstract Background Japanese encephalitis (JE) is presumed to be endemic throughout Asia, yet only a few cases have been reported in tropical Asian countries such as Indonesia, Malaysia and the...

Organizational aspects and implementation of data systems in large-scale epidemiological studies in less developed countries (2006)

Ali, Mohammad, Park, Jin-Kyung, Von Seidlein, Lorenz, Acosta, Camilo J, Deen, Jacqueline L, Clemens, John D

Abstract Background In the conduct of epidemiological studies in less developed countries, while great emphasis is placed on study design, data collection, and analysis, often little attention is...

Field evaluation of a rapid immunochromatographic dipstick test for the diagnosis of cholera in a high-risk population (2006)

Wang, Xuan-Yi, Ansaruzzaman, M, Vaz, Raul, Mondlane, Catarina, Lucas, Marcelino ES, Von Seidlein, Lorenz, ...

Abstract Background Early detection of cholera outbreaks is crucial for the implementation of the most appropriate control strategies. Methods The performance of an immunochromatographic dipstick...

Relationship between neighbourhood-level killed oral cholera vaccine coverage and protective efficacy: evidence for herd immunity (2006)

Emch, Michael, Ali, Mohammad, Park, Jin-Kyung, Yunus, Mohammad, Sack, David A, Clemens, John D

Objectives The effectiveness of vaccines in populations must consider both direct and indirect protection. This study reanalyses data from a large individually randomized oral cholera vaccine trial...

Relationship between neighbourhood-level killed oral cholera vaccine coverage and protective efficacy: evidence for herd immunity (2006)

Emch, Michael, Ali, Mohammad, Park, Jin-Kyung, Yunus, Mohammad, Sack, David A., Clemens, John D.

Objectives The effectiveness of vaccines in populations must consider both direct and indirect protection. This study reanalyses data from a large individually randomized oral cholera vaccine trial...

The burden of diarrhoea, shigellosis, and cholera in North Jakarta, Indonesia: findings from 24 months surveillance (2005)

Agtini, Magdarina D, Soeharno, Rooswanti, Lesmana, Murad, Punjabi, Narain H, Simanjuntak, Cyrus, Wangsasaputra, Ferry, ...

Abstract Background In preparation of vaccines trials to estimate protection against shigellosis and cholera we conducted a two-year community-based surveillance study in an impoverished area of...

Neighborhood size and local geographic variation of health and social determinants (2005)

Ali, Mohammad, Park, Jin-Kyung, Thiem, Vu, Canh, Do, Emch, Michael, Clemens, John D

Abstract Background Spatial filtering using a geographic information system (GIS) is often used to smooth health and ecological data. Smoothing disease data can help us understand local...

A mass vaccination campaign targeting adults and children to prevent typhoid fever in Hechi; Expanding the use of Vi polysaccharide vaccine in Southeast China: A cluster-randomized trial (2005)

Yang, Jin, Acosta, Camilo J, Si, Guo-ai, Zeng, Jun, Li, Cui-yun, Liang, Da-bin, ...

Abstract Background One of the goals of this study was to learn the coverage, safety and logistics of a mass vaccination campaign against typhoid fever in children and adults using locally produced...

Further evidence for association of hepatitis C infection with parenteral schistosomiasis treatment in Egypt (2002)

Rao, Malla R, Naficy, Abdollah B, Darwish, Medhat A, Darwish, Nebal M, Schisterman, Enrique, Clemens, John D, ...

Abstract Background Hepatitis C virus (HCV) infection and schistosomiasis are major public health problems in the Nile Delta of Egypt. To control schistosomiasis, mass treatment campaigns using...

Maternal Serum Caffeine Metabolites and Small-for-Gestational Age Birth (2002)

Klebanoff, Mark A., Levine, Richard J., Clemens, John D., Wilkins, Diana G.

To determine whether the third-trimester maternal serum concentration of paraxanthine, caffeine's primary metabolite, is associated with delivery of a small-for-gestational age infant (birth weight...

Epidemiology of postshigellosis persistent diarrhea in young children (2001)

Ahmed, Faruque, Ansaruzzaman, M., Haque, Emdadul, Rao, Malla R., Clemens, John D.

Dysentery accounts for 20% of the 4.6 million diarrhea-associated deaths among children in developing countries, with the risk from death in dysenteric persistent diarrhea 10-fold higher than that in...

Pathogenicity and Convalescent Excretion of Campylobacter in Rural Egyptian Children (2001)

Rao, Malla R., Naficy, Abdollah B., Savarino, Stephen J., Abu-Elyazeed, Remon, Wierzba, Thomas F., Peruski, Leonard F., ...

Campylobacter infection in developing countries has not received much public health attention because of the observation that infections are not associated with disease beyond the first 6 months of...

Petrogenesis of Mafic to Felsic Plutonic Rock Associations: the Calc-alkaline Querigut Complex, French Pyrenees (2000)

ROBERTS, MALCOLM P., PIN, CHRISTIAN, CLEMENS, JOHN D., PAQUETTE, JEAN-LOUIS

The Que´rigut mafic–felsic rock association comprises two main magma series. The first is felsic comprising a granodiorite–tonalite, a monzogranite and a biotite granite. The second is...

Seroepidemiology of Helicobacter pylori infection in a population of Egyptian children (2000)

Naficy, Abdollah B, Frenck, Robert W, Abu-Elyazeed, Remon, Kim, Yongdai, Rao, Malla R, Savarino, Stephen J, ...

Background To describe the seroepidemiology of Helicobacter pylori infection in a population of Egyptian children under 3 years. Methods A cohort of children under 36 months, residing in Abu Homos,...

Epidemiology of Rotavirus Diarrhea in Egyptian Children and Implications for Disease Control (1999)

Naficy, Abdollah B., Abu-Elyazeed, Remon, Holmes, Jennifer L., Rao, Malla R., Savarino, Stephen J., Kim, Yongdai, ...

Reliable epidemiologic data are essential for formulating effective policy to control rotavirus disease through immunization. The objective of this study was to describe the epidemiology of rotavirus...

Serum Cotinine Concentration and Self-reported Smoking during Pregnancy (1998)

Klebanoff, Mark A., Levine, Richard J., Clemens, John D., DerSimonian, Rebecca, Wilkins, Diana G.

Although during pregnancy there is a better correlation between matermal serum cotinine concentration and adverse outcome than between self-reported smoking and such an outcome, few studies of...

Estimation of Vaccine Efficacy in the Presence of Waning: Application to Cholera Vaccines (1998)

Durham, L. Kathryn, Longini, Ira M., Halloran, M. Elizabeth, Clemens, John D., Azhar, Nizam, Rao, Malla

The authors present a nonparametric method for estimating vaccine efficacy as a smooth function of time from vaccine trials. Use of the method requires a minimum of assumptions. Estimation is based...

Epidemiology of shigellosis among children exposed to cases of Shigella dysentery: a multivariate assessment (1997)

Ahmed, Faruqui, Clemens, John D., Rao, Malla R., Ansaruzzaman, Mohammad, Haque, Emdadul

We followed 1,756 young, rural Bangladeshi children less than five years of age for one month after identification of sentinel Shigella patients in their neighborhoods. Two hundred nineteen (12%)...

Maternal Smoking During Pregnancy and Childhood Cancer (1996)

Klebanoff, Mark A., Clemens, John D., Read, Jennifer S.

The association between maternal smoking during pregnancy and childhood cancer was investigated using prospectively collected data from 54,795 livebom children in the Collaborative Perinatal Project...

Comparison of Heated Water-Filled Mattress and Space-Heated Room with Infant Incubator in Providing Warmth to Low Birthweight Newborns (1994)

GREEN-ABATE, CARMELA, TAFARI, NEBIAT, RAO, MALLA R, YU, KAI F, CLEMENS, JOHN D

Background Prevention of excessive heat loss is fundamental to survival of low birthweight (LBW) newboms. The use of infant incubators (INC) is beyond the resources of developing countries, and the...

Moderate Low Birth Weight and Infectious Disease Mortality during Infancy and Childhood (1994)

Read, Jennifer S., Clemens, John D., Klebanoff, Mark A.

The purpose of this study was to determine whether moderately low birth weight, singleton babies without congenital anomalies are at increased risk for postperinatal infectious disease mortality. The...

Family Latrines and Paediatric Shigellosis in Rural Bangladesh: Benefit or Risk? (1994)

AHMED, FARUQUE, CLEMENS, JOHN D, RAO, MALLA R, BANIK, A K

BackgroundThe potential benefits of installing excreta disposal facilities on the burden of paediatric diarrhoea in less-developed settings remain controversial. We conducted a longitudinal study to...

Nonparticipation as a Determinant of Adverse Health Outcomes in a Field Trial of Oral Cholera Vaccines (1992)

Clemens, John D., Rao, Malla, Sack, David A., Ahmed, Faruque, Chakraborty, J., ...

The authors estimated the incidence rates of cholera and death between 1985 and 1988 for 32,642 age- and sex-eligible persons who did not participate in a randomized, placebo-controlled field trial...

Assessment of the Prevalence and Risk Factors for Human Immunodeficiency Virus Type 1 (HIV-1) Infection among College Students Using Three Survey Methods (1991)

Kotloff, Karen L., Tacket, Carol O., Clemens, John D., Wasserman, Steven S., Cowan, Jane E., Bridwell, Margaret W., ...

To evaluate the seroprevalence and risk factors for human immunodeficiency virus type 1 (HIV-1) infection among undergraduate college students, the authors simultaneously conducted three types of...

BREAST FEEDING AND THE RISK OF SEVERE CHOLERA IN RURAL BANGLADESHI CHILDREN (1990)

CLEMENS, JOHN D., SACK, DAVID A., HARRIS, JEFFREY R., KHAN, M. R., CHAKRABORTY, J., CHOWDHURY, SHAHRIAR, ...

The association between breast feeding and the risk of severe cholera was examined in a case-control study of rural Bangladeshi children under 36 months of age who were studied in 1985–1986 during...

Methodological Considerations in Defining Chronic Diarrhoea Using a Distributional Approach (1990)

STANTON, BONITA F, CLEMENS, JOHN D, AHMED, SHAHNAZ

Stanton B F (The International Centre for Diarrhoeal Disease Research—Bangladesh, Dhaka, Bangladesh), Clemens J D and Ahmed S. Methodological considerations in defining chronic diarrhoea using a...

Exclusion of Clinically Atypical or Microbiologically Mixed Diarrhoeal Episodes from Outcome Events in a Field Trial of Oral Cholera Vaccines (1989)

CLEMENS, JOHN D, STANTON, BONITA F, HARRIS, JEFFREY R, CHAKRABORTY, J, SACK, DAVID A, RAO, MALLA R, ...

Clemens J D (International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh), Stanton B F, Harris J R, Chakraborty J, Sack D A, Rao M R, Ahmed F, Ansaruzzaman M, Yunus M,...

Discontinuation of breast-feeding during episodes of diarrhoea in rural Bangladeshi children (1988)

Clemens, John D., Harris, Jeffery R., Sack, David A., Huda, Md. N., Chowdhury, Shahriar, Ali, Md, ...

Discontinuation of breast-feeding during an episode of childhood diarrhoea is widely regarded as a common, high-risk practice in the developing world. We studied cessation of breast-feeding in a...

Cross-protection by B subunit-whole cell cholera vaccine against diarrhea associated with heat-labile toxin-producing enterotoxigenic Escherichia coli: results of a large-scale field trial (1988)

Clemens, John D., Sack, David A., Harris, Jeffery R., Chakraborty, J., Neogy, P.K., Stanton, B., ...

The B subunit (BS) of cholera toxin and that of the heat-labile enterotoxin (LT) of enterotoxigenic Escherichia coli (ETEC) are antigenically similar. We therefore assessed whether a combined cholera...

Field trial of oral cholera vaccines in Bangladesh: results of one year of follow-up (1988)

Clemens, John D., Harris, Jeffery R., Sack, David A., Chakraborty, J., Ahmed, Faruque, Stanton, Bonita F., ...

We assessed the protective efficacy (PE) of three doses of B subunit-killed whole cell (BS-WC) and killed whole cell-only (WC) oral cholera vaccines in a randomized, double-blind trial among 62,285...

Impact of B subunit killed whole-cell and killed whole-cell-only oral vaccines against cholera upon treated diarrhoeal illness and mortality in an area endemic for cholera (1988)

Clemens, John D., Sack, David A., Harris, Jeffery R., Chakraborty, J., Khan, M.R., Stanton, Bonita F., ...

The impact of B subunit killed whole-cell (BS-WC) and killed whole-cell-only (WC) oral cholera vaccines was assessed in a randomised double-blind trial in rural Bangladesh. 62,285 children aged 2-15...

MEASLES VACCINATION AND CHILDHOOD MORTALITY IN RURAL BANGLADESH (1988)

CLEMENS, JOHN D., STANTON, BONITA F., CHAKRABORTY, J., CHOWDHURY, SHAHRIAR, RAO, MALLA R., MOHAMMED, ALI, ...

Clemens, J. D. (Center for Vaccine Development, U. of Maryland School of Medicine, Baltimore, MD 21201), B. F. Stanton, J. Chakraborty, S. Chowdhury, M. R. Rao, M. AH, S. Zimicki, and B. Wojtyniak....

The Influence of Gender on Determinants of Urban Childhood Mortality in Bangladesh (1988)

STANTON, BONITA F, CLEMENS, JOHN D

To assess sociodemographic characteristics predicting childhood mortality in urban Bangladesh, we conducted a case-control study of subjects selected from 51 low and middle class areas of urban Dhaka...

An educational intervention for altering water-sanitation behaviors to reduce childhood diarrhea in urban Bangladesh : i. Application of the case-control method for development of an intervention (1987)

Clemens, John D., Stanton, Bonita F.

A case-control study was performed to develop an empirically based intervention for improving water-sanitation practices and rates of childhood diarrhea among families residing in urban Bangladesh....

B subunit-whole cell and whole cell-only oral vaccines against cholera: studies on reactogenicity and immunogenicity (1987)

Clemens, John D., Stanton, Bonita F., Chakraborty, J., Sack, David A., Khan, M.R., Huda, S., ...

We conducted a randomized trial among persons in rural Bangladesh to evaluate the side effects and immunogenicity of orally administered B subunit-killed whole cell (BS-WC) and killed whole cell-only...

Oral rehydration solution--too little or too much (1987)

Stanton, Bonita F., Rowland, Michael G. M., Clemens, John D.

Data from studies on actual use of packaged oral rehydration solution (ORS) in Bangladesh are summarized and their impact evaluated. In 6 studies in clinic settings only 2 clinics used enough ORS to...

AN EDUCATIONAL INTERVENTION FOR ALTERING WATER-SANITATION BEHAVIORS TO REDUCE CHILDHOOD DIARRHEA IN URBAN BANGLADESH: I. APPLICATION OF THE CASE-CONTROL METHOD FOR DEVELOPMENT OF AN INTERVENTION (1987)

CLEMENS, JOHN D., STANTON, BONITA F.

A case-control study was performed to develop an empirically based intervention for improving water-sanitation practices and rates of childhood diarrhea among families residing in urban Bangladesh....

AN EDUCATIONAL INTERVENTION FOR ALTERING WATER-SANITATION BEHAVIORS TO REDUCE CHILDHOOD DIARRHEA IN URBAN BANGLADESH: II. A RANDOMIZED TRIAL TO ASSESS THE IMPACT OF THE INTERVENTION ON HYGIENIC BEHAVIORS AND RATES OF DIARRHEA (1987)

STANTON, BONITA F., CLEMENS, JOHN D.

An educational intervention was designed to improve three water-sanitation behaviors empirically shown to be associated with high rates of childhood diarrhea in Dhaka, Bangladesh: lack of handwashing...

Field trial of oral cholera vaccines in Bangladesh (1986)

Clemens, John D., Sack, David A., Harris, Jeffery R., Chakraborty, J., Khan, M.R., Stanton, Bonita F., ...

The protective efficacy of oral B subunit killed whole-cell (BS-WC) and killed whole-cell (WC) cholera vaccines was assessed in 63 498 Bangladeshi children aged 2-15 years and women aged over 15...

Breast feeding as a determinant of severity in shigellosis. Evidence for protection throughout the first three years of life in Bangladeshi children (1986)

Clemens, John D., Stanton, Bonita, Stoll, Barbara, Shahid, Nigar S., Banu, Hasina

Little is known about the effect of breast feeding upon the severity of illness due to specific diarrheal pathogens. Using a systematically sampled and evaluated population of children aged less than...

BREAST FEEDING AS A DETERMINANT OF SEVERITY IN SHIGELLOSIS: EVIDENCE FOR PROTECTION THROUGHOUT THE FIRST THREE YEARS OF LIFE IN BANGLADESHI CHILDREN (1986)

CLEMENS, JOHN D., STANTON, BONITA, STOLL, BARBARA, SHAHID, NIGAR S., BANU, HASINA

Little is known about the effect of breast feeding upon the severity of illness due to specific dlarrheal pathogens. Using a systematically sampled and evaluated population of children aged

Rotavirus diarrhoea: an expanding clinical spectrum (1983)

Clemens, John D., Ahmed, Mosifuddin, Butler, Thomas, Greenough III, William B., Sack, David A., Stanton, Bonita F.

To explore the clinical spectrum of rotavirus diarrhoea in Bangladeshi children, we reviewed surveillance data from randomly selected diarrhoeal cases who were intensively studied at the...

Phenotypic Diversity of Enterotoxigenic Escherichia coli Strains from a Community-Based Study of Pediatric Diarrhea in Periurban Egypt

Peruski, Leonard F., Kay, Bradford A., El-Yazeed, Remon Abu, El-Etr, Sahar H., Cravioto, Alejandro, Wierzba, Thomas F., ...

No past studies of diarrhea in children of the Middle East have examined in detail the phenotypes of enterotoxigenic Escherichia coli (ETEC) strains, which are important pathogens in this setting....

Induction of Systemic Antifimbria and Antitoxin Antibody Responses in Egyptian Children and Adults by an Oral, Killed Enterotoxigenic Escherichia coli plus Cholera Toxin B Subunit Vaccine

Hall, Eric R., Wierzba, Thomas F., Åhrén, Christina, Rao, Malla R., Bassily, Samir, Francis, Wagdy, ...

We assessed serologic responses to an oral, killed whole-cell enterotoxigenic Escherichia coli plus cholera toxin B-subunit (ETEC-rCTB) vaccine in 73 Egyptian adults, 105 schoolchildren, and 93...

High Disease Burden of Diarrhea Due to Enterotoxigenic Escherichia coli among Rural Egyptian Infants and Young Children

Rao, Malla R., Abu-Elyazeed, Remon, Savarino, Stephen J., Naficy, Abdollah B., Wierzba, Thomas F., Abdel-Messih, Ibrahim, ...

The incidence of enterotoxigenic Escherichia coli diarrhea among Egyptian children was 1.5 episodes per child per year and accounted for 66% of all first episodes of diarrhea after birth. The...

Phenotypic Profiles of Enterotoxigenic Escherichia coli Associated with Early Childhood Diarrhea in Rural Egypt

Shaheen, Hind I., Khalil, Sami B., Rao, Malla R., Elyazeed, Remon Abu, Wierzba, Thomas F., Peruski, Leonard F., ...

Enterotoxigenic Escherichia coli (ETEC) causes substantial diarrheal morbidity and mortality in young children in countries with limited resources. We determined the phenotypic profiles of 915 ETEC...

Pandemic Serovars (O3:K6 and O4:K68) of Vibrio parahaemolyticus Associated with Diarrhea in Mozambique: Spread of the Pandemic into the African Continent

Ansaruzzaman, M., Lucas, Marcelino, Deen, Jacqueline L., Bhuiyan, N. A., Wang, Xuan-Yi, Safa, Ashrafus, ...

Forty-two episodes of Vibrio parahaemolyticus infections were detected in Beira, Mozambique, from January to May 2004. The majority of the isolates (81%) belonged to the pandemic serovars (O3:K6 and...

Detection of Shigella by a PCR Assay Targeting the ipaH Gene Suggests Increased Prevalence of Shigellosis in Nha Trang, Vietnam

Thiem, Vu Dinh, Sethabutr, Orntipa, Von Seidlein, Lorenz, Van Tung, Tran, Canh, Do Gia, Chien, Bui Trong, ...

Shigella spp. are exquisitely fastidious gram-negative organisms which frequently escape detection by traditional culture methods. To get a more complete understanding of the disease burden caused by...

Phenotypic Diversity of Enterotoxigenic Escherichia coli Strains from a Community-Based Study of Pediatric Diarrhea in Periurban Egypt

Peruski, Leonard F., Kay, Bradford A., El-Yazeed, Remon Abu, El-Etr, Sahar H., Cravioto, Alejandro, Wierzba, Thomas F., ...

No past studies of diarrhea in children of the Middle East have examined in detail the phenotypes of enterotoxigenic Escherichia coli (ETEC) strains, which are important pathogens in this setting....

Induction of Systemic Antifimbria and Antitoxin Antibody Responses in Egyptian Children and Adults by an Oral, Killed Enterotoxigenic Escherichia coli plus Cholera Toxin B Subunit Vaccine

Hall, Eric R., Wierzba, Thomas F., Åhrén, Christina, Rao, Malla R., Bassily, Samir, Francis, Wagdy, ...

We assessed serologic responses to an oral, killed whole-cell enterotoxigenic Escherichia coli plus cholera toxin B-subunit (ETEC-rCTB) vaccine in 73 Egyptian adults, 105 schoolchildren, and 93...

High Disease Burden of Diarrhea Due to Enterotoxigenic Escherichia coli among Rural Egyptian Infants and Young Children

Rao, Malla R., Abu-Elyazeed, Remon, Savarino, Stephen J., Naficy, Abdollah B., Wierzba, Thomas F., Abdel-Messih, Ibrahim, ...

The incidence of enterotoxigenic Escherichia coli diarrhea among Egyptian children was 1.5 episodes per child per year and accounted for 66% of all first episodes of diarrhea after birth. The...

Detection of Shigella by a PCR Assay Targeting the ipaH Gene Suggests Increased Prevalence of Shigellosis in Nha Trang, Vietnam

Thiem, Vu Dinh, Sethabutr, Orntipa, Von Seidlein, Lorenz, Van Tung, Tran, Canh, Do Gia, Chien, Bui Trong, ...

Shigella spp. are exquisitely fastidious gram-negative organisms which frequently escape detection by traditional culture methods. To get a more complete understanding of the disease burden caused by...

Phenotypic Profiles of Enterotoxigenic Escherichia coli Associated with Early Childhood Diarrhea in Rural Egypt

Shaheen, Hind I., Khalil, Sami B., Rao, Malla R., Elyazeed, Remon Abu, Wierzba, Thomas F., Peruski, Leonard F., ...

Enterotoxigenic Escherichia coli (ETEC) causes substantial diarrheal morbidity and mortality in young children in countries with limited resources. We determined the phenotypic profiles of 915 ETEC...

Pandemic Serovars (O3:K6 and O4:K68) of Vibrio parahaemolyticus Associated with Diarrhea in Mozambique: Spread of the Pandemic into the African Continent

Ansaruzzaman, M., Lucas, Marcelino, Deen, Jacqueline L., Bhuiyan, N. A., Wang, Xuan-Yi, Safa, Ashrafus, ...

Forty-two episodes of Vibrio parahaemolyticus infections were detected in Beira, Mozambique, from January to May 2004. The majority of the isolates (81%) belonged to the pandemic serovars (O3:K6 and...

Genomic analysis of the Mozambique strain of Vibrio cholerae O1 reveals the origin of El Tor strains carrying classical CTX prophage

Faruque, Shah M., Tam, Vincent C., Chowdhury, Nityananda, Diraphat, Pornphan, Dziejman, Michelle, Heidelberg, John F., ...

Cholera outbreaks in subSaharan African countries are caused by strains of the El Tor biotype of toxigenic Vibrio cholerae O1. The El Tor biotype is the causative agent of the current seventh cholera...

Controlling Endemic Cholera with Oral Vaccines

Longini, Ira M, Nizam, Azhar, Ali, Mohammad, Yunus, Mohammad, Shenvi, Neeta, Clemens, John D

Using data from Bangladesh, Ira Longini and colleagues develop a mathematical model predicting that oral vaccination of 50%-70% of the population could control cholera transmission in an endemic...

The High Burden of Cholera in Children: Comparison of Incidence from Endemic Areas in Asia and Africa

Deen, Jacqueline L., Von Seidlein, Lorenz, Sur, Dipika, Agtini, Magdarina, Lucas, Marcelino E. S., Lopez, Anna Lena, ...

Cholera is an often forgotten disease affecting the world's forgotten people. When a large cholera outbreak occurs, the disease appears briefly on the radar of public attention. Some unfortunate...

Antimicrobial Drug Resistance of Salmonella enterica Serovar Typhi in Asia and Molecular Mechanism of Reduced Susceptibility to the Fluoroquinolones▿

Chau, Tran Thuy, Campbell, James Ian, Galindo, Claudia M., Van Minh Hoang, Nguyen, Diep, To Song, Nga, Tran Thu Thi, ...

This study describes the pattern and extent of drug resistance in 1,774 strains of Salmonella enterica serovar Typhi isolated across Asia between 1993 and 2005 and characterizes the molecular...

Cost-effectiveness of routine immunization to control Japanese encephalitis in Shanghai, China.

Ding, Ding, Kilgore, Paul E., Clemens, John D., Wei, Liu, Zhi-Yi, Xu

OBJECTIVE: To assess the cost-effectiveness of inactivated and live attenuated Japanese encephalitis (JE) vaccines given to infants and children in Shanghai. METHODS: A decision-analytical model was...

The use of a computerized database to monitor vaccine safety in Viet Nam.

Ali, Mohammad, Canh, Gia Do, Clemens, John D., Park, Jin-Kyung, Von Seidlein, Lorenz, Minh, Tan Truong, ...

Health information systems to monitor vaccine safety are used in industrialized countries to detect adverse medical events related to vaccinations or to prove the safety of vaccines. There are no...

Enhanced disease surveillance through private health care sector cooperation in Karachi, Pakistan: experience from a vaccine trial.

Khan, Mohammad Imran, Sahito, Shah Muhammad, Khan, Mohammad Javed, Wassan, Shafi Mohammad, Shaikh, Abdul Wahab, Maheshwari, Ashok Kumar, ...

INTRODUCTION: In research projects such as vaccine trials, accurate and complete surveillance of all outcomes of interest is critical. In less developed countries where the private sector is the...

Trend and disease burden of bacillary dysentery in China (1991-2000).

Wang, Xuan-yi, Tao, Fangbiao, Xiao, Donglou, Lee, Hyejon, Deen, Jacqueline, Gong, Jian, ...

OBJECTIVE: We aimed to determine the burden of bacillary dysentery in China, its cross-regional variations, trends in morbidity and mortality, the causative bacterial species and antimicrobial...

Cholera Outbreaks Caused by an Altered Vibrio cholerae O1 El Tor Biotype Strain Producing Classical Cholera Toxin B in Vietnam in 2007 to 2008 ▿

Nguyen, Binh Minh, Lee, Je Hee, Cuong, Ngo Tuan, Choi, Seon Young, Hien, Nguyen Tran, Anh, Dang Duc, ...

Vibrio cholerae O1 isolates collected during cholera outbreaks occurring from late 2007 to early 2008 in northern Vietnam were revealed to represent an altered strain containing the RS1 element...