Grann, Martin, Danesh, John, Fazel, Seena
Abstract Background High rates of repeat offending are common across nations that are socially and culturally different. Although psychiatric disorders are believed to be risk factors for violent...
John Danesh, Stephen Kaptoge, Andrea G. Mann, Nadeem Sarwar, Angela Wood, Sara B. Angleman, ...
BackgroundThe relevance to coronary heart disease (CHD) of cytokines that govern inflammatory cascades, such as interleukin-6 (IL-6), may be underestimated because such mediators are short acting and...
Sagoo, Gurdeep S., Tatt, Iain, Salanti, Georgia, Butterworth, Adam S., Sarwar, Nadeem, Van Maarle, Merel, ...
Lipoprotein lipase (LPL) is a key enzyme in lipoprotein metabolism and a major candidate gene for coronary heart disease (CHD). The authors assessed associations between 7 LPL polymorphisms and lipid...
BMC Psychiatry BioMed Central (2008)
Martin Grann, John Danesh, Seena Fazel
Research article The association between psychiatric diagnosis and violent re-offending in adult offenders in the community
Sarwar, Nadeem, Sattar, Naveed, Gudnason, Vilmundur, Danesh, John
Aims It is uncertain whether there are associations between circulating levels of insulin markers and coronary heart disease (CHD) risk. We report an updated meta-analysis of studies of circulating...
Higgins, Julian P. T., Little, Julian, Ioannidis, John P. A., Bray, Molly S., Manolio, Teri A., Smeeth, Liam, ...
Emanuele Di Angelantonio, John Danesh, Gudny Eiriksdottir, Vilmundur Gudnason
BackgroundEnd-stage chronic kidney disease is associated with striking excesses of cardiovascular mortality, but it is uncertain to what extent renal function is related to risk of subsequent...
Zheng Ye, Honglin Song, Paul Pharoah, John Danesh
Large meta-analysis finds little evidence for a link between gene variants encoding inactive or less active variants of detoxifying enzymes and lung cancer risk.
Zheng Ye, Honglin Song, Paul Pharoah, John Danesh
Background Glutathione S-transferases (GSTs) are known to abolish or reduce the activities of intracellular enzymes that help detoxify environmental carcinogens, such as those found in tobacco smoke....
Fibrinogen and coronary heart disease: test of causality by 'Mendelian randomization' (2006)
Keavney, Bernard, Danesh, John, Parish, Sarah, Palmer, Alison, Clark, Sarah, Youngman, Linda, ...
Background Blood concentrations of fibrinogen have been associated with coronary heart disease risk in epidemiological studies, but it is uncertain whether this association is causal or reflects...
Fibrinogen and coronary heart disease: test of causality by 'Mendelian randomization' (2006)
Keavney, Bernard, Danesh, John, Parish, Sarah, Palmer, Alison, Clark, Sarah, Youngman, Linda, ...
Background Blood concentrations of fibrinogen have been associated with coronary heart disease risk in epidemiological studies, but it is uncertain whether this association is causal or reflects...
Jeremy G. Wheeler, Gudny Eiriksdottir, Vilmundur Gudnason, John Danesh
The largest ever prospective analysis and meta-analysis of uric acid in coronary heart disease finds no evidence that uric acid is useful in predicting coronary heart disease.
Jeremy G. Wheeler, Gudny Eiriksdottir, Vilmundur Gudnason, John Danesh
Background It has been suggested throughout the past fifty years that serum uric acid concentrations can help predict the future risk of coronary heart disease (CHD), but the epidemiological evidence...
A Network of Investigator Networks in Human Genome Epidemiology (2005)
Ioannidis, John P. A., Bernstein, Jonine, Boffetta, Paolo, Danesh, John, Dolan, Siobhan, Hartge, Patricia, ...
The task of identifying genetic determinants for complex, multigenetic diseases is hampered by small studies, publication and reporting biases, and lack of common standards worldwide. The authors...
A Network of Investigator Networks in Human Genome Epidemiology (2005)
Ioannidis, John P. A., Bernstein, Jonine, Boffetta, Paolo, Danesh, John, Dolan, Siobhan, Hartge, Patricia, ...
The task of identifying genetic determinants for complex, multigenetic diseases is hampered by small studies, publication and reporting biases, and lack of common standards worldwide. The authors...
A Network of Investigator Networks in Human Genome Epidemiology (2005)
Ioannidis, John P. A., Bernstein, Jonine, Boffetta, Paolo, Danesh, John, Dolan, Siobhan, Hartge, Patricia, ...
The task of identifying genetic determinants for complex, multigenetic diseases is hampered by small studies, publication and reporting biases, and lack of common standards worldwide. The authors...
Wheeler, Jeremy G, Mussolino, Michael E, Gillum, Richard F, Danesh, John
Aims We aimed to assess potential associations between different leucocyte components and coronary heart disease (CHD) in a prospective cohort study, and to put these findings in context of other...
Keavney, Bernard, Palmer, Alison, Parish, Sarah, Clark, Sarah, Youngman, Linda, Danesh, John, ...
Background Blood lipid concentrations are causally related to the risk of coronary heart disease (CHD). Various associations between CHD risk and genes that moderately affect plasma lipid levels have...
Keavney, Bernard, Palmer, Alison, Parish, Sarah, Clark, Sarah, Youngman, Linda, Danesh, John, ...
Background Blood lipid concentrations are causally related to the risk of coronary heart disease (CHD). Various associations between CHD risk and genes that moderately affect plasma lipid levels have...
Serious mental disorders in 23 000 prisoners: a systematic review of 62 surveys (2002)
Background: About 9 million people are imprisoned worldwide, but the number with serious mental disorders (psychosis, major depression, and antisocial personality disorder) is unknown. We did a...
Chronic infection and coronary heart disease / (1999)
Work carried out in The Dept. of Clinical Medicine.
Low grade inflammation and coronary heart disease: prospective study and updated meta-analyses
Danesh, John, Whincup, Peter, Walker, Mary, Lennon, Lucy, Thomson, Andrew, Appleby, Paul, ...
Chlamydia pneumoniae IgG titres and coronary heart disease: prospective study and meta-analysis
Danesh, John, Whincup, Peter, Walker, Mary, Lennon, Lucy, Thomson, Andrew, Appleby, Paul, ...
Postcodes as useful markers of social class: population based study in 26 000 British households
Danesh, John, Gault, Simon, Semmence, Jo, Appleby, Paul, Peto, Richard
Objective: To find out if chronic infection with Helicobacter pylori is correlated with risk factors for coronary heart disease.
Is Helicobacter pylori a Factor in Coronary Atherosclerosis?
Danesh, John, Koreth, John, Youngman, Linda, Collins, Rory, Arnold, J. Ranjit, Balarajan, Yarlini, ...
Wheeler, Jeremy G, Juzwishin, Kelsey D. M, Eiriksdottir, Gudny, Gudnason, Vilmundur, Danesh, John
The largest ever prospective analysis and meta-analysis of uric acid in coronary heart disease finds no evidence that uric acid is useful in predicting coronary heart disease
Ye, Zheng, Song, Honglin, Higgins, Julian P. T, Pharoah, Paul, Danesh, John
Large meta-analysis finds little evidence for a link between gene variants encoding inactive or less active variants of detoxifying enzymes and lung cancer risk.
Low grade inflammation and coronary heart disease: prospective study and updated meta-analyses
Danesh, John, Whincup, Peter, Walker, Mary, Lennon, Lucy, Thomson, Andrew, Appleby, Paul, ...
Chlamydia pneumoniae IgG titres and coronary heart disease: prospective study and meta-analysis
Danesh, John, Whincup, Peter, Walker, Mary, Lennon, Lucy, Thomson, Andrew, Appleby, Paul, ...
Postcodes as useful markers of social class: population based study in 26 000 British households
Danesh, John, Gault, Simon, Semmence, Jo, Appleby, Paul, Peto, Richard
Objective: To find out if chronic infection with Helicobacter pylori is correlated with risk factors for coronary heart disease.
Is Helicobacter pylori a Factor in Coronary Atherosclerosis?
Danesh, John, Koreth, John, Youngman, Linda, Collins, Rory, Arnold, J. Ranjit, Balarajan, Yarlini, ...
Wheeler, Jeremy G, Juzwishin, Kelsey D. M, Eiriksdottir, Gudny, Gudnason, Vilmundur, Danesh, John
The largest ever prospective analysis and meta-analysis of uric acid in coronary heart disease finds no evidence that uric acid is useful in predicting coronary heart disease
Ye, Zheng, Song, Honglin, Higgins, Julian P. T, Pharoah, Paul, Danesh, John
Large meta-analysis finds little evidence for a link between gene variants encoding inactive or less active variants of detoxifying enzymes and lung cancer risk.
Di Angelantonio, Emanuele, Danesh, John, Eiriksdottir, Gudny, Gudnason, Vilmundur
John Danesh and colleagues conclude there may be a moderate increase in risk of coronary heart disease associated with very low estimated glomerular filtration rate.
Danesh, John, Kaptoge, Stephen, Mann, Andrea G, Sarwar, Nadeem, Wood, Angela, Angleman, Sara B, ...
John Danesh and colleagues show that long-term IL-6 levels are associated with coronary heart disease risk, thus highlighting the potential relevance of IL-6−mediated pathways to coronary heart...