John F. Reilly

High-throughput Morphometric Analysis of Individual Neurons (2004)

Wu, Chi-Cheng, Reilly, John F., Young, Warren G., Morrison, John H., Bloom, Floyd E.

To facilitate high-throughput quantitative analysis of neuronal structure, this study optimized the diOlistic method of whole neuron labeling to examine multiple neurons in fixed brain, and optimized...

High-throughput Morphometric Analysis of Individual Neurons (2004)

Wu, Chi-Cheng, Reilly, John F., Young, Warren G., Morrison, John H., Bloom, Floyd E.

To facilitate high-throughput quantitative analysis of neuronal structure, this study optimized the diOlistic method of whole neuron labeling to examine multiple neurons in fixed brain, and optimized...

High-throughput Morphometric Analysis of Individual Neurons (2004)

Wu, Chi-Cheng, Reilly, John F., Young, Warren G., Morrison, John H., Bloom, Floyd E.

To facilitate high-throughput quantitative analysis of neuronal structure, this study optimized the diOlistic method of whole neuron labeling to examine multiple neurons in fixed brain, and optimized...

Dentate gyrus volume is reduced before onset of plaque formation in PDAPP mice: A magnetic resonance microscopy and stereologic analysis (2003)

Redwine, Jeffrey M., Kosofsky, Barry, Jacobs, Russell E., Games, Dora, Reilly, John F., Morrison, John H., ...

High-resolution magnetic resonance microscopy (MRM) was used to determine regional brain volumetric changes in a mouse model of Alzheimer's disease. These transgenic (Tg) mice overexpress human...

Internal haemorrhoids /--by J.F. Reilly. (1883)

Reilly, John F.

Handwritten thesis submitted in partial fulfillment of the requirements of the degree of M.D.

Amyloid deposition in the hippocampus and entorhinal cortex: Quantitative analysis of a transgenic mouse model

Reilly, John F., Games, Dora, Rydel, Russell E., Freedman, Stephen, Schenk, Dale, Young, Warren G., ...

Various transgenic mouse models of Alzheimer's disease (AD) have been developed that overexpress mutant forms of amyloid precursor protein in an effort to elucidate more fully the potential role of...

Dentate gyrus volume is reduced before onset of plaque formation in PDAPP mice: A magnetic resonance microscopy and stereologic analysis

Redwine, Jeffrey M., Kosofsky, Barry, Jacobs, Russell E., Games, Dora, Reilly, John F., Morrison, John H., ...

High-resolution magnetic resonance microscopy (MRM) was used to determine regional brain volumetric changes in a mouse model of Alzheimer's disease. These transgenic (Tg) mice overexpress human...

Adult mouse brain gene expression patterns bear an embryologic imprint

Zapala, Matthew A., Hovatta, Iiris, Ellison, Julie A., Wodicka, Lisa, Del Rio, Jo A., Tennant, Richard, ...

The current model to explain the organization of the mammalian nervous system is based on studies of anatomy, embryology, and evolution. To further investigate the molecular organization of the adult...

A novel role for farnesyl pyrophosphate synthase in fibroblast growth factor-mediated signal transduction.

Reilly, John F, Martinez, Shawndra D, Mickey, Gregory, Maher, Pamela A

Farnesyl pyrophosphate synthase (FPPS) catalyses the formation of a key cellular intermediate in isoprenoid metabolic pathways. Here we describe a novel role for this enzyme in fibroblast growth...

Amyloid deposition in the hippocampus and entorhinal cortex: Quantitative analysis of a transgenic mouse model

Reilly, John F., Games, Dora, Rydel, Russell E., Freedman, Stephen, Schenk, Dale, Young, Warren G., ...

Various transgenic mouse models of Alzheimer's disease (AD) have been developed that overexpress mutant forms of amyloid precursor protein in an effort to elucidate more fully the potential role of...

Dentate gyrus volume is reduced before onset of plaque formation in PDAPP mice: A magnetic resonance microscopy and stereologic analysis

Redwine, Jeffrey M., Kosofsky, Barry, Jacobs, Russell E., Games, Dora, Reilly, John F., Morrison, John H., ...

High-resolution magnetic resonance microscopy (MRM) was used to determine regional brain volumetric changes in a mouse model of Alzheimer's disease. These transgenic (Tg) mice overexpress human...

Adult mouse brain gene expression patterns bear an embryologic imprint

Zapala, Matthew A., Hovatta, Iiris, Ellison, Julie A., Wodicka, Lisa, Del Rio, Jo A., Tennant, Richard, ...

The current model to explain the organization of the mammalian nervous system is based on studies of anatomy, embryology, and evolution. To further investigate the molecular organization of the adult...

A novel role for farnesyl pyrophosphate synthase in fibroblast growth factor-mediated signal transduction.

Reilly, John F, Martinez, Shawndra D, Mickey, Gregory, Maher, Pamela A

Farnesyl pyrophosphate synthase (FPPS) catalyses the formation of a key cellular intermediate in isoprenoid metabolic pathways. Here we describe a novel role for this enzyme in fibroblast growth...

Phase 2 trial of oral vorinostat (suberoylanilide hydroxamic acid, SAHA) for refractory cutaneous T-cell lymphoma (CTCL)

Duvic, Madeleine, Talpur, Rakshandra, Ni, Xiao, Zhang, Chunlei, Hazarika, Parul, Kelly, Cecilia, ...

The activity and safety of the histone deacetylase inhibitor vorinostat (suberoylanilide hydroxamic acid, SAHA) were evaluated in patients with refractory cutaneous T-cell lymphoma (CTCL). Group 1...

Importin β–Mediated Nuclear Import of Fibroblast Growth Factor Receptor: Role in Cell Proliferation

Reilly, John F., Maher, Pamela A.

Although growth factor receptors are generally thought to carry out their role in signal transduction at the cell surface, many of these transmembrane proteins translocate to the nucleus after ligand...

A Quantitative Volumetric Micro-Computed Tomography Method to Analyze Lung Tumors in Genetically Engineered Mouse Models

Haines, Brian B, Bettano, Kimberly A, Chenard, Melissa, Sevilla, Raquel S, Ware, Christopher, Angagaw, Minilik H, ...

Two genetically engineered, conditional mouse models of lung tumor formation, K-rasLSL-G12D and K-rasLSL-G12D/p53LSL-R270H, are commonly used to model human lung cancer. Developed by Tyler Jacks and...