piggyBacis an effective tool for functional analysis of the Plasmodium falciparumgenome (2009)
Balu, Bharath, Chauhan, Chitra, Maher, Steven P, Shoue, Douglas A, Kissinger, Jessica C, Fraser, Malcolm J, ...
Abstract Background Much of the Plasmodium falciparum genome encodes hypothetical proteins with limited homology to other organisms. A lack of robust tools for genetic manipulation of the parasite...
Maher, Steven P, Balu, Bharath, Shoue, Doug A, Weissenbach, Matthew E, Adams, John H
Abstract Background Cloning of parasites by limiting dilution is an essential and rate-limiting step in many aspects of malaria research including genomic and genetic manipulation studies. The...
Tamez, Pamela A., Bhattacharjee, Souvik, Van Ooij, Christiaan, Hiller, N. Luisa, Llin S, Manuel, Balu, Bharath, ...
Plasmodium falciparum is the protozoan parasite that causes the most virulent of human malarias. The blood stage parasites export several hundred proteins into their host erythrocyte that underlie...
Epitope-specific humoral immunity to Plasmodium vivax Duffy binding protein. (2003)
Xainli, Jia, Cole-Tobian, Jennifer L., Baisor, Moses, Kastens, Will, Bockarie, Moses, Yazdani, Syed Shams, ...
Erythrocyte invasion by Plasmodium vivax is completely dependent on binding to the Duffy blood group antigen by the parasite Duffy binding protein (DBP). The receptor-binding domain of this protein...
Michon, Pascal, Stevens, Jamie R., Kaneko, Osamu, Adams, John H.
Malaria parasites invade erythrocytes in a process mediated by a series of molecular interactions. Invasion of human erythrocytes by Plasmodium vivax is dependent upon the presence of a single...
Morrison, Samuel G., Adams, John H.
Thesis (B.S.)--Massachusetts Institute of Technology, Dept. of Naval Architecture and Marine Engineering, 1944.
A family of chimeric erythrocyte binding proteins of malaria parasites
Kappe, Stefan H. I., Noe, Amy R., Fraser, Tresa S., Blair, Peter L., Adams, John H.
Proteins sequestered within organelles of the apical complex of malaria merozoites are involved in erythrocyte invasion, but few of these proteins and their interaction with the host erythrocyte have...
Exploring the transcriptome of the malaria sporozoite stage
Kappe, Stefan H. I., Gardner, Malcolm J., Brown, Stuart M., Ross, Jessica, Matuschewski, Kai, Ribeiro, Jose M., ...
Most studies of gene expression in Plasmodium have been concerned with asexual and/or sexual erythrocytic stages. Identification and cloning of genes expressed in the preerythrocytic stages lag far...
Michon, Pascal, Fraser, Tresa, Adams, John H.
Malaria merozoites require the presence of specific surface receptors on the red blood cell for invasion. Plasmodium vivax, requires the Duffy blood group antigen as an obligate receptor for...
Transcripts of developmentally regulated Plasmodium falciparum genes quantified by real-time RT–PCR
Blair, Peter L., Witney, Adam, Haynes, J. David, Moch, J. Kathleen, Carucci, Daniel J., Adams, John H.
Plasmodium falciparum intraerythrocytic development is a complex process. Development proceeds rapidly from the trophozoite phase of nutrient acquisition and growth through to the synthetic and...
Epitope-Specific Humoral Immunity to Plasmodium vivax Duffy Binding Protein
Xainli, Jia, Cole-Tobian, Jennifer L., Baisor, Moses, Kastens, Will, Bockarie, Moses, Yazdani, Syed Shams, ...
Erythrocyte invasion by Plasmodium vivax is completely dependent on binding to the Duffy blood group antigen by the parasite Duffy binding protein (DBP). The receptor-binding domain of this protein...
Ohas, Eunita A., Adams, John H., Waitumbi, John N., Orago, Alloys S. S., Barbosa, Arnoldo, Lanar, David E., ...
Region II of the 175-kDa erythrocyte-binding antigen (EBA-175RII) of Plasmodium falciparum is functionally important in sialic acid-dependent erythrocyte invasion and is considered a prime target for...
Antibodies against MAEBL Ligand Domains M1 and M2 Inhibit Sporozoite Development In Vitro
Preiser, Peter, Rénia, Laurent, Singh, Naresh, Balu, Bharath, Jarra, William, Voza, Tatiana, ...
MAEBL is a type 1 membrane protein that is implicated in the merozoite invasion of erythrocytes and sporozoite invasion of mosquito salivary glands. This apical organelle protein is structurally...
VanBuskirk, Kelley M., Sevova, Elitza, Adams, John H.
Malaria merozoite invasion of human erythrocytes depends on recognition of specific erythrocyte surface receptors by parasite ligands. Plasmodium vivax merozoite invasion is totally dependent on the...
Balu, Bharath, Shoue, Douglas A., Fraser, Malcolm J., Adams, John H.
Functional analysis of the Plasmodium falciparum genome is restricted because of the limited ability to genetically manipulate this important human pathogen. We have developed an efficient...
A family of chimeric erythrocyte binding proteins of malaria parasites
Kappe, Stefan H. I., Noe, Amy R., Fraser, Tresa S., Blair, Peter L., Adams, John H.
Proteins sequestered within organelles of the apical complex of malaria merozoites are involved in erythrocyte invasion, but few of these proteins and their interaction with the host erythrocyte have...
Exploring the transcriptome of the malaria sporozoite stage
Kappe, Stefan H. I., Gardner, Malcolm J., Brown, Stuart M., Ross, Jessica, Matuschewski, Kai, Ribeiro, Jose M., ...
Most studies of gene expression in Plasmodium have been concerned with asexual and/or sexual erythrocytic stages. Identification and cloning of genes expressed in the preerythrocytic stages lag far...
Michon, Pascal, Fraser, Tresa, Adams, John H.
Malaria merozoites require the presence of specific surface receptors on the red blood cell for invasion. Plasmodium vivax, requires the Duffy blood group antigen as an obligate receptor for...
Transcripts of developmentally regulated Plasmodium falciparum genes quantified by real-time RT–PCR
Blair, Peter L., Witney, Adam, Haynes, J. David, Moch, J. Kathleen, Carucci, Daniel J., Adams, John H.
Plasmodium falciparum intraerythrocytic development is a complex process. Development proceeds rapidly from the trophozoite phase of nutrient acquisition and growth through to the synthetic and...
Epitope-Specific Humoral Immunity to Plasmodium vivax Duffy Binding Protein
Xainli, Jia, Cole-Tobian, Jennifer L., Baisor, Moses, Kastens, Will, Bockarie, Moses, Yazdani, Syed Shams, ...
Erythrocyte invasion by Plasmodium vivax is completely dependent on binding to the Duffy blood group antigen by the parasite Duffy binding protein (DBP). The receptor-binding domain of this protein...
Ohas, Eunita A., Adams, John H., Waitumbi, John N., Orago, Alloys S. S., Barbosa, Arnoldo, Lanar, David E., ...
Region II of the 175-kDa erythrocyte-binding antigen (EBA-175RII) of Plasmodium falciparum is functionally important in sialic acid-dependent erythrocyte invasion and is considered a prime target for...
Antibodies against MAEBL Ligand Domains M1 and M2 Inhibit Sporozoite Development In Vitro
Preiser, Peter, Rénia, Laurent, Singh, Naresh, Balu, Bharath, Jarra, William, Voza, Tatiana, ...
MAEBL is a type 1 membrane protein that is implicated in the merozoite invasion of erythrocytes and sporozoite invasion of mosquito salivary glands. This apical organelle protein is structurally...
VanBuskirk, Kelley M., Sevova, Elitza, Adams, John H.
Malaria merozoite invasion of human erythrocytes depends on recognition of specific erythrocyte surface receptors by parasite ligands. Plasmodium vivax merozoite invasion is totally dependent on the...
Balu, Bharath, Shoue, Douglas A., Fraser, Malcolm J., Adams, John H.
Functional analysis of the Plasmodium falciparum genome is restricted because of the limited ability to genetically manipulate this important human pathogen. We have developed an efficient...
Saenz, Fabian E., Balu, Bharath, Smith, Jonah, Mendonca, Sarita R., Adams, John H.
Malaria transmission depends on infective stages in the mosquito salivary glands. Plasmodium sporozoites that mature in midgut oocysts must traverse the hemocoel and invade the mosquito salivary...
Tamez, Pamela A., Bhattacharjee, Souvik, Van Ooij, Christiaan, Hiller, N. Luisa, Llinás, Manuel, Balu, Bharath, ...
Plasmodium falciparum is the protozoan parasite that causes the most virulent of human malarias. The blood stage parasites export several hundred proteins into their host erythrocyte that underlie...
Bhattacharjee, Souvik, Van Ooij, Christiaan, Balu, Bharath, Adams, John H., Haldar, Kasturi
In blood-stage infection by the human malaria parasite Plasmodium falciparum, export of proteins from the intracellular parasite to the erythrocyte is key to virulence. This export is mediated by a...