John HE Nash

malTknockout mutation invokes a stringent type gene-expression profile in Actinobacillus pleuropneumoniaein bronchoalveolar fluid (2009)

Lone, Abdul G, Deslandes, Vincent, Nash, John HE, Jacques, Mario, MacInnes, Janet I

Abstract Background Actinobacillus pleuropneumoniae causes contagious pleuropneumonia, an economically important disease of commercially reared pigs throughout the world. To cause this disease, A....

Microarray-based comparative genomic profiling of reference strains and selected Canadian field isolates of Actinobacillus pleuropneumoniae (2009)

Gouré, Julien, Findlay, Wendy A, Deslandes, Vincent, Bouevitch, Anne, Foote, Simon J, MacInnes, Janet I, ...

Abstract Background Actinobacillus pleuropneumoniae , the causative agent of porcine pleuropneumonia, is a highly contagious respiratory pathogen that causes severe losses to the swine industry...

The genome of Aeromonas salmonicidasubsp. salmonicidaA449: insights into the evolution of a fish pathogen (2008)

Reith, Michael E, Singh, Rama K, Curtis, Bruce, Boyd, Jessica M, Bouevitch, Anne, Kimball, Jennifer, ...

Abstract Background Aeromonas salmonicida subsp. salmonicida is a Gram-negative bacterium that is the causative agent of furunculosis, a bacterial septicaemia of salmonid fish. While other species of...

Comparative genomic assessment of Multi-Locus Sequence Typing: rapid accumulation of genomic heterogeneity among clonal isolates of Campylobacter jejuni (2008)

Taboada, Eduardo N, MacKinnon, Joanne M, Luebbert, Christian C, Gannon, Victor PJ, Nash, John HE, Rahn, Kris

Abstract Background Multi-Locus Sequence Typing (MLST) has emerged as a leading molecular typing method owing to its high ability to discriminate among bacterial isolates, the relative ease with...

Comparative genomic analysis of Campylobacter jejuniassociated with Guillain-Barré and Miller Fisher syndromes: neuropathogenic and enteritis-associated isolates can share high levels of genomic similarity (2007)

Taboada, Eduardo N, Van Belkum, Alex, Yuki, Nobuhiro, Acedillo, Rey R, Godschalk, Peggy CR, Koga, Michiaki, ...

Abstract Background Campylobacter jejuni infection represents the most frequent antecedent infection triggering the onset of the neuropathic disorders Guillain-Barré syndrome (GBS) and Miller Fisher...

Transcriptional profiling of Actinobacillus pleuropneumoniaeunder iron-restricted conditions (2007)

Deslandes, Vincent, Nash, John HE, Harel, Josée, Coulton, James W, Jacques, Mario

Abstract Background To better understand effects of iron restriction on Actinobacillus pleuropneumoniae and to identify new potential vaccine targets, we conducted transcript profiling studies using...

Evolution of competence and DNA uptake specificity in the Pasteurellaceae (2006)

Redfield, Rosemary J, Findlay, Wendy A, Bossé, Janine, Kroll, J Simon, Cameron, Andrew DS, Nash, John HE

Abstract Background Many bacteria can take up DNA, but the evolutionary history and function of natural competence and transformation remain obscure. The sporadic distribution of competence suggests...

Comparative genomics profiling of clinical isolates of Aeromonas salmonicidausing DNA microarrays (2006)

Nash, John HE, Findlay, Wendy A, Luebbert, Christian C, Mykytczuk, Oksana L, Foote, Simon J, Taboada, Eduardo N, ...

Abstract Background Aeromonas salmonicida has been isolated from numerous fish species and shows wide variation in virulence and pathogenicity. As part of a larger research program to identify...

A new approach for the analysis of bacterial microarray-based Comparative Genomic Hybridization: insights from an empirical study (2005)

Taboada, Eduardo N, Acedillo, Rey R, Luebbert, Christian C, Findlay, Wendy A, Nash, John HE

Abstract Background Microarray-based Comparative Genomic Hybridization (M-CGH) has been used to characterize the extensive intraspecies genetic diversity found in bacteria at the whole-genome level....