John J. Donnelly

Antibody Responses to Capsular Polysaccharide Backbone and O-Acetate Side Groups of Streptococcus pneumoniae Type 9V in Humans and Rhesus Macaques

McNeely, Tessie B., Staub, Joan M., Rusk, Cynthia M., Blum, Michael J., Donnelly, John J.

Streptococcus pneumoniae is responsible for high rates of pneumococcal bacteremia, meningitis, pneumonia, and acute otitis media worldwide. Protection from disease is conferred by antibodies specific...

Protective CD4+ and CD8+ T Cells against Influenza Virus Induced by Vaccination with Nucleoprotein DNA

Ulmer, Jeffrey B., Fu, Tong-Ming, Deck, R. Randall, Friedman, Arthur, Guan, Liming, DeWitt, Corrille, ...

DNA vaccination is an effective means of eliciting both humoral and cellular immunity, including cytotoxic T lymphocytes (CTL). Using an influenza virus model, we previously demonstrated that...

Purification and Characterization of Oligomeric Envelope Glycoprotein from a Primary R5 Subtype B Human Immunodeficiency Virus

Srivastava, Indresh K., Stamatatos, Leonidas, Legg, Harold, Kan, Elaine, Fong, Anne, Coates, Stephen R., ...

Human immunodeficiency virus (HIV) continues to be a major public health problem throughout the world, with high levels of mortality and morbidity associated with AIDS. Considerable efforts to...

Evaluation of Envelope Vaccines Derived from the South African Subtype C Human Immunodeficiency Virus Type 1 TV1 Strain

Lian, Ying, Srivastava, Indresh, Gómez-Román, V. Rául, Zur Megede, Jan, Sun, Yide, Kan, Elaine, ...

Human immunodeficiency virus type 1 (HIV-1) subtype C infections are on the rise in Sub-Saharan Africa and Asia. Therefore, there is a need to develop an HIV vaccine capable of eliciting broadly...

Expression and Immunogenicity of Sequence-Modified Human Immunodeficiency Virus Type 1 Subtype B pol and gagpol DNA Vaccines

Zur Megede, Jan, Otten, Gillis R., Doe, Barbara, Liu, Hong, Leung, Louisa, Ulmer, Jeffrey B., ...

Control of the worldwide AIDS pandemic may require not only preventive but also therapeutic immunization strategies. To meet this challenge, the next generation of human immunodeficiency virus type 1...

Antibody Responses to Capsular Polysaccharide Backbone and O-Acetate Side Groups of Streptococcus pneumoniae Type 9V in Humans and Rhesus Macaques

McNeely, Tessie B., Staub, Joan M., Rusk, Cynthia M., Blum, Michael J., Donnelly, John J.

Streptococcus pneumoniae is responsible for high rates of pneumococcal bacteremia, meningitis, pneumonia, and acute otitis media worldwide. Protection from disease is conferred by antibodies specific...

Protective CD4+ and CD8+ T Cells against Influenza Virus Induced by Vaccination with Nucleoprotein DNA

Ulmer, Jeffrey B., Fu, Tong-Ming, Deck, R. Randall, Friedman, Arthur, Guan, Liming, DeWitt, Corrille, ...

DNA vaccination is an effective means of eliciting both humoral and cellular immunity, including cytotoxic T lymphocytes (CTL). Using an influenza virus model, we previously demonstrated that...

Purification and Characterization of Oligomeric Envelope Glycoprotein from a Primary R5 Subtype B Human Immunodeficiency Virus

Srivastava, Indresh K., Stamatatos, Leonidas, Legg, Harold, Kan, Elaine, Fong, Anne, Coates, Stephen R., ...

Human immunodeficiency virus (HIV) continues to be a major public health problem throughout the world, with high levels of mortality and morbidity associated with AIDS. Considerable efforts to...

Expression and Immunogenicity of Sequence-Modified Human Immunodeficiency Virus Type 1 Subtype B pol and gagpol DNA Vaccines

Zur Megede, Jan, Otten, Gillis R., Doe, Barbara, Liu, Hong, Leung, Louisa, Ulmer, Jeffrey B., ...

Control of the worldwide AIDS pandemic may require not only preventive but also therapeutic immunization strategies. To meet this challenge, the next generation of human immunodeficiency virus type 1...

Evaluation of Envelope Vaccines Derived from the South African Subtype C Human Immunodeficiency Virus Type 1 TV1 Strain

Lian, Ying, Srivastava, Indresh, Gómez-Román, V. Rául, Zur Megede, Jan, Sun, Yide, Kan, Elaine, ...

Human immunodeficiency virus type 1 (HIV-1) subtype C infections are on the rise in Sub-Saharan Africa and Asia. Therefore, there is a need to develop an HIV vaccine capable of eliciting broadly...

β7-integrin-independent enhancement of mucosal and systemic anti-HIV antibody responses following combined mucosal and systemic gene delivery

Goodsell, Amanda, Zhou, Fengmin, Gupta, Soumi, Singh, Manmohan, Malyala, Padma, Kazzaz, Jina, ...

Vaccination strategies that can block or limit heterosexual human immunodeficiency virus (HIV) transmissions to local and systemic tissues are the goal of much research effort. Herein, in a mouse...