John M. Hawdon

Publication List Details

Period

1991 - 2009

Number

13

Co-Authors

Interaction of hookworm 14-3-3 with the forkhead transcription factor DAF-16 requires intact Akt phosphorylation sites (2009)

Kiss, Joshua E, Gao, Xin, Krepp, Joseph M, Hawdon, John M

Abstract Background Third-stage infective larvae (L3) of hookworms are in an obligatory state of developmental arrest that ends upon entering the definitive host, where they receive a signal that...

Plant Vermicides of Haitian Vodou Show In Vitro Activity Against Larval Hookworm (2008)

Beverly J. Wolpert, Max G. Beauvoir, Elizabeth Fortson Wells, John M. Hawdon

Haitian Vodou priests (houngans) and priestesses (mambos) use plant remedies to treat many illnesses, including intestinal parasite infections. The present study screened 12 plants used in Vodou...

Progress in the development of a recombinant vaccine for human hookworm disease: The Human Hookworm Vaccine Initiative (2003)

Hotez, Peter J., Zhan, Bin, Bethony, Jeffrey M., Loukas, Alex, Williamson, Angela, Goud, Gaddam Narsa, ...

Hookworm infection is one of the most important parasitic infections of humans, possibly outranked only by malaria as a cause of misery and suffering. An estimated 1.2 billion people are infected...

Molecular Cloning of a Novel Multidomain Kunitz-Type Proteinase Inhibitor From the Hookworm Ancylostoma caninum (2003)

John M. Hawdon, Bennett Datu, Melissa Crowell

Degenerate oligonucleotide primers derived from conserved serine protease inhibitors were used to amplify a 90–base pair (bp) amplicon from an Ancylostoma caninum adult-stage complementary...

EFFECT OF VACCINATIONS WITH RECOMBINANT FUSION PROTEINS ON ANCYLOSTOMA CANINUM HABITAT SELECTION IN THE CANINE INTESTINE (2002)

Peter J. Hotez, James Ashcom, Zhan Bin, Jeffrey Bethony, Angela Williamson, John M. Hawdon, ...

Laboratory dogs were vaccinated subcutaneously with 3 different recombinant fusion proteins, each precipitated with alum or calcium phosphate. The vaccinated dogs were then challenged orally with 400...

Epidemiology of Necator Americanus Hookworm Infections in Xiulongkan Village, Hainan Province, China: High Prevalence and Intensity Among Middle-Aged and Elderly Residents (2001)

Nishiena S. Gandhi, Chen Jizhang, Kaveh Khoshnood, Xing Fuying, Li Shanwen, Liu Yaoruo, ...

Hookworm is highly endemic to Hainan Province, an island located in the South China Sea. To investigate the prevalence and intensity of infection in the area, the village of Xiulongkan was surveyed...

Variation between ASP-1 Molecules from Ancylostoma caninum in China and the United States (2000)

Shan Qiang, Zhan Bin, Xiao Shu-hua, Feng Zheng, Peter Hotez, John M. Hawdon

Hookworm infection continues to be a serious problem in rural areas of China. Rapid reinfection and high cost limit the effectiveness of deworming programs. Vaccination offers an attractive...

Epidemiology of Hookworm Infection in Itagua, Paraguay: a Cross Sectional Study (1999)

Nora Labiano-Abello, Jorge Canese, Maria Eugenia Velazquez, John M Hawdon, Mark L Wilson, Peter J Hotez

A cross-sectional study in Itagua, Paraguay tested 192 people for the presence, intensity and species of hookworm infection. Fifty-nine percent of these individuals were found to be infected....

Epidemiology of hookworm infection in Itagua, Paraguay: a cross sectional study (1999)

Labiano-Abello,Nora, Canese,Jorge, Velazquez,Maria Eugenia, Hawdon,John M, Wilson,Mark L, Hotez,Peter J

A cross-sectional study in Itagua, Paraguay tested 192 people for the presence, intensity and species of hookworm infection. Fifty-nine percent of these individuals were found to be infected....

Hookworm infectious process : host signals and parasite responses / (1991)

Hawdon, John M.

Thesis (Ph.D. in Parasitology) -- Graduate School of Arts and Sciences, University of Pennsylvania, 1991.

Biochemical Characterization and Vaccine Potential of a Heme-Binding Glutathione Transferase from the Adult Hookworm Ancylostoma caninum

Zhan, Bin, Liu, Sen, Perally, Samirah, Xue, Jian, Fujiwara, Ricardo, Brophy, Peter, ...

We report the cloning and expression of Ac-GST-1, a novel glutathione S-transferase from the adult hookworm Ancylostoma caninum, and its possible role in parasite blood feeding and as a vaccine...