John M. Murray

Publication List Details

Period

1935 - 2009

Number

28

Co-Authors

Cassette deletion in multiple shRNA lentiviral vectors for HIV-1 and its impact on treatment success (2009)

Mcintyre, Glen J, Yu, Yi-Hsin, Tran, Anna, Jaramillo, Angel B, Arndt, Allison J, Millington, Michelle L, ...

Abstract Background Multiple short hairpin RNA (shRNA) gene therapy strategies are currently being investigated for treating viral diseases such as HIV-1. It is important to use several different...

MATERIALS AND METHODS (2008)

John M. Murray

A number of reports suggesting a link between microtubules and membrane-associated elements have been published (1-7). Unfortunately, these examples have not been suited for structural studies at...

Significant reduction in HIV prevalence according to male circumcision intervention in sub-Saharan Africa (2008)

Londish, Gregory J, Murray, John M

Background Observations that reduced adult HIV prevalence in sub-Saharan Africa correlated with levels of male circumcision (MC), have suggested that MC could be used as a preventative measure...

Cytoskeletal Components of an Invasion Machine—The Apical Complex of Toxoplasma gondii (2006)

Ke Hu, Jeff Johnson, Laurence Florens, Martin Fraunholz, Sapna Suravajjala, Camille DiLullo, ...

The apical complex of Toxoplasma gondii is widely believed to serve essential functions in both invasion of its host cells (including human cells), and in replication of the parasite. The...

The Key to Unit Effectiveness - A Supportive Organizational Climate (2003)

Murray, John M.

The operational environment of the 21st Century will place tremendous stress upon future units and their leaders. Whether we end up with the current conceptualization of the FCS, a flattened...

The impact of behavioural changes on the prevalence of human immunodeficiency virus and hepatitis C among injecting drug users (2003)

Murray, John M, Law, Matthew G, Gao, Zhanhai, Kaldor, John M

Background Prevalence of human immunodeficiency virus (HIV) and hepatitis C virus (HCV) in the injecting drug user (IDU) community can differ considerably. In Australia in 1997, HIV prevalence among...

Daughter Cell Assembly in the Protozoan Parasite Toxoplasma gondii

Hu, Ke, Mann, Tara, Striepen, Boris, Beckers, Con J. M., Roos, David S., Murray, John M.

The phylum Apicomplexa includes thousands of species of obligate intracellular parasites, many of which are significant human and/or animal pathogens. Parasites in this phylum replicate by assembling...

Measuring tubulin content in Toxoplasma gondii: A comparison of laser-scanning confocal and wide-field fluorescence microscopy

Swedlow, Jason R., Hu, Ke, Andrews, Paul D., Roos, David S., Murray, John M.

Toxoplasma gondii is an intracellular parasite that proliferates within most nucleated cells, an important human pathogen, and a model for the study of human and veterinary parasitic infections. We...

Interferon regulatory factor-3 is an in vivo target of DNA-PK

Karpova, Alla Y., Trost, Maren, Murray, John M., Cantley, Lewis C., Howley, Peter M.

Eukaryotic cells have evolved complex signaling networks to sense environmental stress and to repair stress-induced damage. IFN regulatory factor-3 (IRF-3) is a transcription factor that plays a...

Cytoskeletal Components of an Invasion Machine—The Apical Complex of Toxoplasma gondii

Hu, Ke, Johnson, Jeff, Florens, Laurence, Fraunholz, Martin, Suravajjala, Sapna, DiLullo, Camille, ...

The apical complex of Toxoplasma gondii is widely believed to serve essential functions in both invasion of its host cells (including human cells), and in replication of the parasite. The...

Dynamics of hepatitis B virus clearance in chimpanzees

Murray, John M., Wieland, Stefan F., Purcell, Robert H., Chisari, Francis V.

Mathematical modeling was performed to test the extent to which cytopathic and noncytopathic T cell effector functions contribute to resolution of hepatitis B virus (HBV) infection in three acutely...

Daughter Cell Assembly in the Protozoan Parasite Toxoplasma gondii

Hu, Ke, Mann, Tara, Striepen, Boris, Beckers, Con J. M., Roos, David S., Murray, John M.

The phylum Apicomplexa includes thousands of species of obligate intracellular parasites, many of which are significant human and/or animal pathogens. Parasites in this phylum replicate by assembling...

Measuring tubulin content in Toxoplasma gondii: A comparison of laser-scanning confocal and wide-field fluorescence microscopy

Swedlow, Jason R., Hu, Ke, Andrews, Paul D., Roos, David S., Murray, John M.

Toxoplasma gondii is an intracellular parasite that proliferates within most nucleated cells, an important human pathogen, and a model for the study of human and veterinary parasitic infections. We...

Interferon regulatory factor-3 is an in vivo target of DNA-PK

Karpova, Alla Y., Trost, Maren, Murray, John M., Cantley, Lewis C., Howley, Peter M.

Eukaryotic cells have evolved complex signaling networks to sense environmental stress and to repair stress-induced damage. IFN regulatory factor-3 (IRF-3) is a transcription factor that plays a...

Dynamics of hepatitis B virus clearance in chimpanzees

Murray, John M., Wieland, Stefan F., Purcell, Robert H., Chisari, Francis V.

Mathematical modeling was performed to test the extent to which cytopathic and noncytopathic T cell effector functions contribute to resolution of hepatitis B virus (HBV) infection in three acutely...

Cytoskeletal Components of an Invasion Machine—The Apical Complex of Toxoplasma gondii

Hu, Ke, Johnson, Jeff, Florens, Laurence, Fraunholz, Martin, Suravajjala, Sapna, DiLullo, Camille, ...

The apical complex of Toxoplasma gondii is widely believed to serve essential functions in both invasion of its host cells (including human cells), and in replication of the parasite. The...

Identification of PhIL1, a Novel Cytoskeletal Protein of the Toxoplasma gondii Pellicle, through Photosensitized Labeling with 5-[125I]Iodonaphthalene-1-Azide

Gilk, Stacey D., Raviv, Yossef, Hu, Ke, Murray, John M., Beckers, Con J. M., Ward, Gary E.

The pellicle of the protozoan parasite Toxoplasma gondii is a unique triple bilayer structure, consisting of the plasma membrane and two tightly apposed membranes of the underlying inner membrane...

Kinetics of Acute Hepatitis B Virus Infection in Humans

Whalley, Simon A., Murray, John M., Brown, Dave, Webster, George J.M., Emery, Vincent C., Dusheiko, Geoffrey M., ...

Using patient data from a unique single source outbreak of hepatitis B virus (HBV) infection, we have characterized the kinetics of acute HBV infection by monitoring viral turnover in the serum...

A novel polymer of tubulin forms the conoid of Toxoplasma gondii

Hu, Ke, Roos, David S., Murray, John M.

Toxoplasma gondii is an obligatory intracellular parasite, an important human pathogen, and a convenient laboratory model for many other human and veterinary pathogens in the phylum Apicomplexa, such...

Evaluating performance in three-dimensional fluorescence microscopy

MURRAY, JOHN M, APPLETON, PAUL L, SWEDLOW, JASON R, WATERS, JENNIFER C

In biological fluorescence microscopy, image contrast is often degraded by a high background arising from out of focus regions of the specimen. This background can be greatly reduced or eliminated by...