John MacMillan

Investigation of the NOTCH3 and TNFSF7 Genes on C19p13 as Candidates for Migraine (2008)

Smith, Robert Anthony, Curtain, Rob, Ovcaric, Micky, Tajouri, Lotfi, MacMillan, John, Griffiths, Lyn

To investigate the migraine locus around the C19p13 region through analysis of the NOTCH3 gene (C19p13.2- p13.1), previously shown to be a gene involved in CADASIL and the TNFSF7 gene (C19p13),...

Investigation of the NOTCH3 and TNFSF7 Genes on C19p13 as Candidates for Migraine (2008)

Smith, Robert Anthony, Curtain, Rob, Ovcaric, Micky, Tajouri, Lotfi, MacMillan, John, Griffiths, Lyn

To investigate the migraine locus around the C19p13 region through analysis of the NOTCH3 gene (C19p13.2- p13.1), previously shown to be a gene involved in CADASIL and the TNFSF7 gene (C19p13),...

Investigation of the NOTCH3 and TNFSF7 Genes on C19p13 as Candidates for Migraine (2008)

Smith, Robert Anthony, Curtain, Rob, Ovcaric, Micky, Tajouri, Lotfi, MacMillan, John, Griffiths, Lyn

To investigate the migraine locus around the C19p13 region through analysis of the NOTCH3 gene (C19p13.2- p13.1), previously shown to be a gene involved in CADASIL and the TNFSF7 gene (C19p13),...

Association analysis of chromosome 1 migraine candidate genes (2007)

Fernandez, Francesca, Curtain, Robert P, Colson, Natalie J, Ovcaric, Micky, MacMillan, John, Griffiths, Lyn R

Abstract Background Migraine with aura (MA) is a subtype of typical migraine. Migraine with aura (MA) also encompasses a rare severe subtype Familial Hemiplegic Migraine (FHM) with several known...

Association analysis of chromosome 1 migraine candidate genes (2007)

Fernandez, Francesca, Curtain, Rob, Colson, Natalie Jane, Ovcaric, Micky, MacMillan, John, Griffiths, Lyn

Background Migraine with aura (MA) is a subtype of typical migraine. Migraine with aura (MA) also encompasses a rare severe subtype Familial Hemiplegic Migraine (FHM) with several known genetic loci....

Association analysis of chromosome 1 migraine candidate genes (2007)

Fernandez, Francesca, Curtain, Rob, Colson, Natalie Jane, Ovcaric, Micky, MacMillan, John, Griffiths, Lyn

Background Migraine with aura (MA) is a subtype of typical migraine. Migraine with aura (MA) also encompasses a rare severe subtype Familial Hemiplegic Migraine (FHM) with several known genetic loci....

Association analysis of chromosome 1 migraine candidate genes (2007)

Fernandez, Francesca, Curtain, Rob, Colson, Natalie Jane, Ovcaric, Micky, MacMillan, John, Griffiths, Lyn

Background Migraine with aura (MA) is a subtype of typical migraine. Migraine with aura (MA) also encompasses a rare severe subtype Familial Hemiplegic Migraine (FHM) with several known genetic loci....

No mutations detected in the INSR gene in a chromosome 19p13 linked migraine pedigree (2006)

Curtain, Rob, Tajouri, Lotfi, Lea, Rodney Arthur, MacMillan, John, Griffiths, Lyn

The aim of this study was to investigate through direct sequencing the insulin receptor (INSR) gene in DNA samples from a migraine affected family previously showing linkage to chromosome 19p13 in an...

No mutations detected in the INSR gene in a chromosome 19p13 linked migraine pedigree (2006)

Curtain, Rob, Tajouri, Lotfi, Lea, Rodney Arthur, MacMillan, John, Griffiths, Lyn

The aim of this study was to investigate through direct sequencing the insulin receptor (INSR) gene in DNA samples from a migraine affected family previously showing linkage to chromosome 19p13 in an...

No mutations detected in the INSR gene in a chromosome 19p13 linked migraine pedigree (2006)

Curtain, Rob, Tajouri, Lotfi, Lea, Rodney Arthur, MacMillan, John, Griffiths, Lyn

The aim of this study was to investigate through direct sequencing the insulin receptor (INSR) gene in DNA samples from a migraine affected family previously showing linkage to chromosome 19p13 in an...

Association analysis of a highly polymorphic CAG Repeat in the human potassium channel gene KCNN3and migraine susceptibility (2005)

Curtain, Robert, Sundholm, James, Lea, Rod, Ovcaric, Mick, MacMillan, John, Griffiths, Lyn

Abstract Background Migraine is a polygenic multifactorial disease, possessing environmental and genetic causative factors with multiple involved genes. Mutations in various ion channel genes are...

Association analysis of a highly polymorphic CAG Repeat in the human potassium channel gene KCNN3 and migraine susceptibility. (2005)

Curtain, Rob, Sundholm, James Rodney, Lea, Rodney Arthur, Ovcaric, Micky, MacMillan, John, Griffiths, Lyn

Background Migraine is a polygenic multifactorial disease, possessing environmental and genetic causative factors with multiple involved genes. Mutations in various ion channel genes are responsible...

Investigation of hormone receptor genes in migraine. (2005)

Colson, Natalie Jane, Lea, Rodney Arthur, Quinlan, Sharon Anne, MacMillan, John, Griffiths, Lyn

Migraine is a common neurological condition with a complex mode of inheritance. Steroid hormones have long been implicated in migraine, although their role remains unclear. Our investigation...

Association analysis of a highly polymorphic CAG Repeat in the human potassium channel gene KCNN3 and migraine susceptibility. (2005)

Curtain, Rob, Sundholm, James Rodney, Lea, Rodney Arthur, Ovcaric, Micky, MacMillan, John, Griffiths, Lyn

Background Migraine is a polygenic multifactorial disease, possessing environmental and genetic causative factors with multiple involved genes. Mutations in various ion channel genes are responsible...

Investigation of hormone receptor genes in migraine. (2005)

Colson, Natalie Jane, Lea, Rodney Arthur, Quinlan, Sharon Anne, MacMillan, John, Griffiths, Lyn

Migraine is a common neurological condition with a complex mode of inheritance. Steroid hormones have long been implicated in migraine, although their role remains unclear. Our investigation...

Association analysis of a highly polymorphic CAG Repeat in the human potassium channel gene KCNN3 and migraine susceptibility. (2005)

Curtain, Rob, Sundholm, James Rodney, Lea, Rodney Arthur, Ovcaric, Micky, MacMillan, John, Griffiths, Lyn

Background Migraine is a polygenic multifactorial disease, possessing environmental and genetic causative factors with multiple involved genes. Mutations in various ion channel genes are responsible...

Investigation of hormone receptor genes in migraine. (2005)

Colson, Natalie Jane, Lea, Rodney Arthur, Quinlan, Sharon Anne, MacMillan, John, Griffiths, Lyn

Migraine is a common neurological condition with a complex mode of inheritance. Steroid hormones have long been implicated in migraine, although their role remains unclear. Our investigation...

The methylenetetrahydrofolate reductase gene variant C677T influences susceptibility to migraine with aura (2004)

Lea, Rod A, Ovcaric, Micky, Sundholm, James, MacMillan, John, Griffiths, Lyn R

Abstract Background The C677T variant in the methylenetetrahydrofolate reductase (MTHFR) gene is associated with increased levels of circulating homocysteine and is a mild risk factor for vascular...

The estrogen receptor 1 G594A polymorphism is associated with migraine susceptibility in two independent case/control groups (2004)

Colson, Natalie Jane, Lea, Rodney Arthur, Quinlan, Sharon Anne, MacMillan, John, Griffiths, Lyn

Migraine is a painful and debilitating disorder with a significant genetic component. Steroid hormones, in particular estrogen, have long been considered to play a role in migraine, as variations in...

The methylenetetrahydofolate reductase gene variant C677T influences susceptibility to migraine with aura (2004)

Lea, Rodney Arthur, Ovcaric, Micky, Sundholm, James, MacMillan, John, Griffiths, Lyn

Background The C677T variant in the methylenetetrahydrofolate reductase (MTHFR) gene is associated with increased levels of circulating homocysteine and is a mild risk factor for vascular disease....

The estrogen receptor 1 G594A polymorphism is associated with migraine susceptibility in two independent case/control groups (2004)

Colson, Natalie Jane, Lea, Rodney Arthur, Quinlan, Sharon Anne, MacMillan, John, Griffiths, Lyn

Migraine is a painful and debilitating disorder with a significant genetic component. Steroid hormones, in particular estrogen, have long been considered to play a role in migraine, as variations in...

The methylenetetrahydofolate reductase gene variant C677T influences susceptibility to migraine with aura (2004)

Lea, Rodney Arthur, Ovcaric, Micky, Sundholm, James, MacMillan, John, Griffiths, Lyn

Background The C677T variant in the methylenetetrahydrofolate reductase (MTHFR) gene is associated with increased levels of circulating homocysteine and is a mild risk factor for vascular disease....

The estrogen receptor 1 G594A polymorphism is associated with migraine susceptibility in two independent case/control groups (2004)

Colson, Natalie Jane, Lea, Rodney Arthur, Quinlan, Sharon Anne, MacMillan, John, Griffiths, Lyn

Migraine is a painful and debilitating disorder with a significant genetic component. Steroid hormones, in particular estrogen, have long been considered to play a role in migraine, as variations in...

The methylenetetrahydofolate reductase gene variant C677T influences susceptibility to migraine with aura (2004)

Lea, Rodney Arthur, Ovcaric, Micky, Sundholm, James, MacMillan, John, Griffiths, Lyn

Background The C677T variant in the methylenetetrahydrofolate reductase (MTHFR) gene is associated with increased levels of circulating homocysteine and is a mild risk factor for vascular disease....

Investigation of the NOTCH3 and TNFSF7 Genes on C19p13 as Candidates for Migraine

Smith, Robert A, Curtain, Robert, Ovcaric, Mick, Tajouri, Lotti, MacMillan, John, Griffiths, Lyn

To investigate the migraine locus around the C19p13 region through analysis of the NOTCH3 gene (C19p13.2-p13.1), previously shown to be a gene involved in CADASIL and the TNFSF7 gene (C19p13),...