Jonas Blomberg

RetroTector online, a rational tool for analysis of retroviral elements in small and medium size vertebrate genomic sequences (2009)

Sperber, Göran, Lövgren, Anders, Eriksson, Nils-Einar, Benachenhou, Farid, Blomberg, Jonas

Abstract Background The rapid accumulation of genomic information in databases necessitates rapid and specific algorithms for extracting biologically meaningful information. More or less complete...

Annotation and visualization of endogenous retroviral sequences using the Distributed Annotation System (DAS) and eBioX (2009)

Martínez Barrio, Álvaro, Lagercrantz, Erik, Sperber, Göran O, Blomberg, Jonas, Bongcam-Rudloff, Erik

Abstract Background The Distributed Annotation System (DAS) is a widely used network protocol for sharing biological information. The distributed aspects of the protocol enable the use of various...

Annotation and visualization of endogenous retroviral sequences using the Distributed Annotation System (DAS) and eBioX (2009)

Barrio, Alvaro Martínez, Lagercrantz, Erik, Sperber, Göran O., Blomberg, Jonas, Bongcam-Rudloff, Erik

BACKGROUND: The Distributed Annotation System (DAS) is a widely used network protocol for sharing biological information. The distributed aspects of the protocol enable the use of various reference...

RetroTector online, a rational tool for analysis of retroviral elements in small and medium size vertebrate genomic sequences (2009)

Sperber, Göran, Lövgren, Anders, Eriksson, Nils-Einar, Benachenhou, Farid, Blomberg, Jonas

BACKGROUND: The rapid accumulation of genomic information in databases necessitates rapid and specific algorithms for extracting biologically meaningful information. More or less complete retroviral...

Multiplex and quantifiable detection of nucleic acid from pathogenic fungi using padlock probes, generic real-time PCR and specific suspension array readout (2009)

Jobs, Magnus, Eriksson, Ronnie, Ekstrand, Charlotta, Ullberg, Måns, Hermann, Björn, Landegren, Ulf, ...

A new concept for multiplex detection and quantification of microbes is here demonstrated on a range of infectious fungal species. Padlock probe methodology in conjunction with qPCR and Luminex™...

International Journal of Neural Systems, Vol. 15, No. 3 (2005) 163--179 (2008)

World Scientific Publishing, Of Human, Endogenous Retroviral, Sequence Groups, Merja Oja, Göran O. Sperber, ...

this article we will use bootstrap for a di#erent purpose. The data set is here sampled B times with replacement, to produce B bootstrap data sets of the size of the original data set. Some samples...

Automated recognition of retroviral sequences in genomic data RetroTector(C) (2007)

Sperber, Göran O., Airola, Tove, Jern, Patric, Blomberg, Jonas

Eukaryotic genomes contain many endogenous retroviral sequences (ERVs). ERVs are often severely mutated, therefore difficult to detect. A platform independent (Java) program package, RetroTector©...

Estimating human endogeneous retrovirus activities in various tissues with a hidden Markov mixture model (2007)

Oja, Merja, Peltonen, Jaakko, Blomberg, Jonas, Kaski, Samuel

Human endogenous retroviruses (HERVs) are ancient viral sequences within the human DNA. Recently, HERV expression has been detected in humans. However, the expression patterns of individual HERVs are...

Methods for estimating human endogenous retrovirus activities from EST databases (2007)

Oja, Merja, Peltonen, Jaakko, Blomberg, Jonas, Kaski, Samuel

Abstract Background Human endogenous retroviruses (HERVs) are surviving traces of ancient retrovirus infections and now reside within the human DNA. Recently HERV expression has been detected in both...

Methods for estimating human endogenous retrovirus activities from EST databases (2007)

Oja, Merja, Peltonen, Jaakko, Blomberg, Jonas, Kaski, Samuel

Background: Human endogenous retroviruses (HERVs) are surviving traces of ancient retrovirus infections and now reside within the human DNA. Recently HERV expression has been detected in both normal...

Use of Endogenous Retroviral Sequences (ERVs) and structural markers for retroviral phylogenetic inference and taxonomy (2005)

Jern, Patric, Sperber, Göran O, Blomberg, Jonas

Abstract Background Endogenous retroviral sequences (ERVs) are integral parts of most eukaryotic genomes and vastly outnumber exogenous retroviruses (XRVs). ERVs with a relatively complete structure...

Compression mechanisms and strenght properties of semi-isostatically densified wood (2004)

Blomberg, Jonas

Since most strength properties increase with increased wood density, densifying wood through compression will increase strength and wear resistance. After densification, wood with originally low...

ERV3 and Related Sequences in Humans: Structure and RNA Expression† (2004)

Ann-catrin Andersson, Zhihong Yun, Göran O. Sperber, Erik Larsson, Jonas Blomberg

The ERV3 locus at chromosome 7q11 is a much studied human endogenous retroviral (HERV) sequence, owing to an env open reading frame (ORF) and placental RNA and protein expression. An analysis of the...

Grouping and visualizing human endogenous retroviruses by bootstrapping median self-organizing maps (2004)

Ieee Personal Use, Merja Oja, Göran Sperber, Jonas Blomberg, Samuel Kaski

About eight percent of the human genome consists of human endogenous retrovirus sequences. Human endogenous retroviruses (HERV) are remains from ancient infections by retroviruses. The HERVs are...

Screening for human T cell leukaemia/lymphoma virus among blood donors in Sweden: cost effectiveness analysis

Tynell, Elsa, Andersson, Soren, Lithander, Eva, Arneborn, Malin, Blomberg, Jonas, Hansson, Hans Bertil, ...

Objective: To analyse the cost effectiveness of a national programme to screen blood donors for infection with the human T cell leukaemia/lymphoma virus.

Identification of Novel Porcine Endogenous Betaretrovirus Sequences in Miniature Swine

Ericsson, Thomas, Oldmixon, Beth, Blomberg, Jonas, Rosa, Margaret, Patience, Clive, Andersson, Göran

PCR amplification of genomic DNA from miniature swine peripheral blood lymphocytes, using primers corresponding to highly conserved regions of the polymerase (pol) gene, allowed the identification of...

Comparison of a Duplex Quantitative Real-Time PCR Assay and the COBAS Amplicor CMV Monitor Test for Detection of Cytomegalovirus

Herrmann, Björn, Larsson, Viviana Cavaglia, Rubin, Carl-Johan, Sund, Fredrik, Eriksson, Britt-Marie, Arvidson, Johan, ...

A duplex quantitative real-time PCR (qPCR) assay was designed to detect both the polymerase gene (pol) and the glycoprotein gene (gB) of cytomegalovirus (CMV). The detection limit of the qPCR was...

Quantitative PCR-Enhanced Immunoassay for Measurement of Enteroviral Immunoglobulin M Antibody and Diagnosis of Aseptic Meningitis

Elfaitouri, Amal, Mohamed, Nahla, Fohlman, Jan, Aspholm, Robert, Frisk, Gun, Friman, Göran, ...

A PCR-enhanced immunoassay (PIA) to detect enterovirus (EV) immunoglobulin M (IgM) for diagnosis of recent EV infection was recently developed. This test was compared with another EV IgM capture...

Sequence Variability, Gene Structure, and Expression of Full-Length Human Endogenous Retrovirus H

Jern, Patric, Sperber, Göran O., Ahlsén, Göran, Blomberg, Jonas

Recently, we identified and classified 926 human endogenous retrovirus H (HERV-H)-like proviruses in the human genome. In this paper, we used the information to, in silico, reconstruct a putative...

ERV3 and Related Sequences in Humans: Structure and RNA Expression†

Andersson, Ann-Catrin, Yun, Zhihong, Sperber, Göran O., Larsson, Erik, Blomberg, Jonas

The ERV3 locus at chromosome 7q11 is a much studied human endogenous retroviral (HERV) sequence, owing to an env open reading frame (ORF) and placental RNA and protein expression. An analysis of the...

Divergent Patterns of Recent Retroviral Integrations in the Human and Chimpanzee Genomes: Probable Transmissions between Other Primates and Chimpanzees†

Jern, Patric, Sperber, Göran O., Blomberg, Jonas

The human genome is littered by endogenous retrovirus sequences (HERVs), which constitute up to 8% of the total genomic sequence. The sequencing of the human (Homo sapiens) and chimpanzee (Pan...

Screening for human T cell leukaemia/lymphoma virus among blood donors in Sweden: cost effectiveness analysis

Tynell, Elsa, Andersson, Soren, Lithander, Eva, Arneborn, Malin, Blomberg, Jonas, Hansson, Hans Bertil, ...

Objective: To analyse the cost effectiveness of a national programme to screen blood donors for infection with the human T cell leukaemia/lymphoma virus.

Identification of Novel Porcine Endogenous Betaretrovirus Sequences in Miniature Swine

Ericsson, Thomas, Oldmixon, Beth, Blomberg, Jonas, Rosa, Margaret, Patience, Clive, Andersson, Göran

PCR amplification of genomic DNA from miniature swine peripheral blood lymphocytes, using primers corresponding to highly conserved regions of the polymerase (pol) gene, allowed the identification of...

Comparison of a Duplex Quantitative Real-Time PCR Assay and the COBAS Amplicor CMV Monitor Test for Detection of Cytomegalovirus

Herrmann, Björn, Larsson, Viviana Cavaglia, Rubin, Carl-Johan, Sund, Fredrik, Eriksson, Britt-Marie, Arvidson, Johan, ...

A duplex quantitative real-time PCR (qPCR) assay was designed to detect both the polymerase gene (pol) and the glycoprotein gene (gB) of cytomegalovirus (CMV). The detection limit of the qPCR was...

Quantitative PCR-Enhanced Immunoassay for Measurement of Enteroviral Immunoglobulin M Antibody and Diagnosis of Aseptic Meningitis

Elfaitouri, Amal, Mohamed, Nahla, Fohlman, Jan, Aspholm, Robert, Frisk, Gun, Friman, Göran, ...

A PCR-enhanced immunoassay (PIA) to detect enterovirus (EV) immunoglobulin M (IgM) for diagnosis of recent EV infection was recently developed. This test was compared with another EV IgM capture...

Sequence Variability, Gene Structure, and Expression of Full-Length Human Endogenous Retrovirus H

Jern, Patric, Sperber, Göran O., Ahlsén, Göran, Blomberg, Jonas

Recently, we identified and classified 926 human endogenous retrovirus H (HERV-H)-like proviruses in the human genome. In this paper, we used the information to, in silico, reconstruct a putative...

ERV3 and Related Sequences in Humans: Structure and RNA Expression†

Andersson, Ann-Catrin, Yun, Zhihong, Sperber, Göran O., Larsson, Erik, Blomberg, Jonas

The ERV3 locus at chromosome 7q11 is a much studied human endogenous retroviral (HERV) sequence, owing to an env open reading frame (ORF) and placental RNA and protein expression. An analysis of the...

Divergent Patterns of Recent Retroviral Integrations in the Human and Chimpanzee Genomes: Probable Transmissions between Other Primates and Chimpanzees†

Jern, Patric, Sperber, Göran O., Blomberg, Jonas

The human genome is littered by endogenous retrovirus sequences (HERVs), which constitute up to 8% of the total genomic sequence. The sequencing of the human (Homo sapiens) and chimpanzee (Pan...

Automated recognition of retroviral sequences in genomic data—RetroTector©

Sperber, Göran O., Airola, Tove, Jern, Patric, Blomberg, Jonas

Eukaryotic genomes contain many endogenous retroviral sequences (ERVs). ERVs are often severely mutated, therefore difficult to detect. A platform independent (Java) program package, RetroTector©...