Jonathan Binkley

Publication List Details

Period

1990 - 2008

Number

6

Co-Authors

Identification of the Otopetrin Domain, a conserved domain in vertebrate otopetrins and invertebrate otopetrin-like family members (2008)

Hughes, Inna, Binkley, Jonathan, Hurle, Belen, Green, Eric D, Sidow, Arend, ...

Abstract Background Otopetrin 1 (Otop1) encodes a multi-transmembrane domain protein with no homology to known transporters, channels, exchangers, or receptors. Otop1 is necessary for the formation...

RNA ligands to human nerve growth factor (1995)

Binkley, Jonathan, Allen, Patrick, Brown, David M., Green, Louis, Tuerk, Craig, Gold, Larry

High affinity RNA ligands to human nerve growth factor (NGF) were selected from pools of random RNA using SELEX [Tuerk, C. and Gold, L. (1990) Science, 249, 505-510]. Nerve growth factor, which is a...

Binding of the bacteriophage T4 regA protein to mRNA targets: an initiator AUG is required (1990)

Unnithan, Shashikala, Green, Louis, Morrissey, Louisa, Binkley, Jonathan, Singer, Britta, Karam, Jim, ...

Bacteriophage T4 regA protein translationally represses the synthesis of a subset of early phage-induced proteins. The protein binds to the translation initiation site of at least two mRNAs and...

The integrity of a cholesterol-binding pocket in Niemann–Pick C2 protein is necessary to control lysosome cholesterol levels

Ko, Dennis C., Binkley, Jonathan, Sidow, Arend, Scott, Matthew P.

The neurodegenerative disease Niemann–Pick Type C2 (NPC2) results from mutations in the NPC2 (HE1) gene that cause abnormally high cholesterol accumulation in cells. We find that purified NPC2, a...

The integrity of a cholesterol-binding pocket in Niemann–Pick C2 protein is necessary to control lysosome cholesterol levels

Ko, Dennis C., Binkley, Jonathan, Sidow, Arend, Scott, Matthew P.

The neurodegenerative disease Niemann–Pick Type C2 (NPC2) results from mutations in the NPC2 (HE1) gene that cause abnormally high cholesterol accumulation in cells. We find that purified NPC2, a...