Jonathan M. Harris

Collocation of Androgen Receptor Gene Mutations in Prostate Cancer 1 (2008)

Grant Buchanan, Norman M. Greenberg, Howard I. Scher, Jonathan M. Harris, Villis R. Marshall, Wayne D. Tilley

Consistent with both the development of the normal prostate gland and prostate tumorigenesis being dependent on testicular androgens, targeting the androgen-signaling axis (i.e., androgen ablation...

The Contribution of Different Androgen Receptor Domains to Receptor Dimerization and Signaling (2008)

Centenera, Margaret Mary, Harris, Jonathan M., Tilley, Wayne Desmond, Butler, Lisa Maree

The androgen receptor (AR) is a ligand-activated transcription factor of the nuclear receptor superfamily that plays a critical role in male physiology and pathology. Activated by binding of the...

The Contribution of Different Androgen Receptor Domains to Receptor Dimerization and Signaling (2008)

Centenera, Margaret Mary, Harris, Jonathan M., Tilley, Wayne Desmond, Butler, Lisa Maree

The androgen receptor (AR) is a ligand-activated transcription factor of the nuclear receptor superfamily that plays a critical role in male physiology and pathology. Activated by binding of the...

The Contribution of Different Androgen Receptor Domains to Receptor Dimerization and Signaling (2008)

Centenera, Margaret Mary, Harris, Jonathan M., Tilley, Wayne Desmond, Butler, Lisa Maree

The androgen receptor (AR) is a ligand-activated transcription factor of the nuclear receptor superfamily that plays a critical role in male physiology and pathology. Activated by binding of the...

Decreased Androgen Receptor Levels and Receptor Function in Breast Cancer Contribute to the Failure of Response to Medroxyprogesterone Acetate (2005)

Buchanan, Grant, Birrell, Stephen N., Peters, Amelia A., Bianco-Miotto, Tina, Ramsay, Katrina, Cops, Elisa J., ...

Previously, we reported that androgen receptor (AR), but not estrogen receptor (ER) or progesterone receptor (PR), is predictive of response to the synthetic progestin, medroxyprogesterone acetate...

Decreased Androgen Receptor Levels and Receptor Function in Breast Cancer Contribute to the Failure of Response to Medroxyprogesterone Acetate (2005)

Buchanan, Grant, Birrell, Stephen N., Peters, Amelia A., Bianco-Miotto, Tina, Ramsay, Katrina, Cops, Elisa J., ...

Previously, we reported that androgen receptor (AR), but not estrogen receptor (ER) or progesterone receptor (PR), is predictive of response to the synthetic progestin, medroxyprogesterone acetate...

Decreased Androgen Receptor Levels and Receptor Function in Breast Cancer Contribute to the Failure of Response to Medroxyprogesterone Acetate (2005)

Buchanan, Grant, Birrell, Stephen N., Peters, Amelia A., Bianco-Miotto, Tina, Ramsay, Katrina, Cops, Elisa J., ...

Previously, we reported that androgen receptor (AR), but not estrogen receptor (ER) or progesterone receptor (PR), is predictive of response to the synthetic progestin, medroxyprogesterone acetate...

A Survey of sustainable development :social and economic dimensions (2005)

Jonathan M. Harris, Global Development And Environment Institute. Tufts University.

Mutation of the androgen receptor causes oncogenic transformation of the prostate (2005)

Han, Guangzhou, Buchanan, Grant, Ittmann, Michael, Harris, Jonathan M., Yu, Xiaoqing, DeMayo, Francesco J., ...

Recent evidence demonstrates that the androgen receptor (AR) continues to influence prostate cancer growth despite medical therapies that reduce circulating androgen ligands to castrate levels and/or...

Mutation of the androgen receptor causes oncogenic transformation of the prostate (2005)

Han, Guangzhou, Buchanan, Grant, Ittmann, Michael, Harris, Jonathan M., Yu, Xiaoqing, DeMayo, Francesco J., ...

Recent evidence demonstrates that the androgen receptor (AR) continues to influence prostate cancer growth despite medical therapies that reduce circulating androgen ligands to castrate levels and/or...

Mutation of the androgen receptor causes oncogenic transformation of the prostate (2005)

Han, Guangzhou, Buchanan, Grant, Ittmann, Michael, Harris, Jonathan M., Yu, Xiaoqing, DeMayo, Francesco J., ...

Recent evidence demonstrates that the androgen receptor (AR) continues to influence prostate cancer growth despite medical therapies that reduce circulating androgen ligands to castrate levels and/or...

Mutation of the androgen receptor causes oncogenic transformation of the prostate (2005)

Han, Guangzhou, Buchanan, Grant, Ittmann, Michael, Harris, Jonathan M., Yu, Xiaoqing, DeMayo, Francesco J., ...

Recent evidence demonstrates that the androgen receptor (AR) continues to influence prostate cancer growth despite medical therapies that reduce circulating androgen ligands to castrate levels and/or...

Decreased Androgen Receptor Levels and Receptor Function in Breast Cancer Contribute to the Failure of Response to Medroxyprogesterone Acetate (2005)

Buchanan, Grant, Birrell, Stephen N., Peters, Amelia A., Bianco-Miotto, Tina, Ramsay, Katrina, Cops, Elisa J., ...

Previously, we reported that androgen receptor (AR), but not estrogen receptor (ER) or progesterone receptor (PR), is predictive of response to the synthetic progestin, medroxyprogesterone acetate...

Mutation of the androgen receptor causes oncogenic transformation of the prostate (2005)

Han, Guangzhou, Buchanan, Grant, Ittmann, Michael, Harris, Jonathan M., Yu, Xiaoqing, DeMayo, Francesco J., ...

Recent evidence demonstrates that the androgen receptor (AR) continues to influence prostate cancer growth despite medical therapies that reduce circulating androgen ligands to castrate levels and/or...

Decreased Androgen Receptor Levels and Receptor Function in Breast Cancer Contribute to the Failure of Response to Medroxyprogesterone Acetate (2005)

Buchanan, Grant, Birrell, Stephen N., Peters, Amelia A., Bianco-Miotto, Tina, Ramsay, Katrina, Cops, Elisa J., ...

Previously, we reported that androgen receptor (AR), but not estrogen receptor (ER) or progesterone receptor (PR), is predictive of response to the synthetic progestin, medroxyprogesterone acetate...

Mutation of the androgen receptor causes oncogenic transformation of the prostate (2005)

Han, Guangzhou, Buchanan, Grant, Ittmann, Michael, Harris, Jonathan M., Yu, Xiaoqing, DeMayo, Francesco J., ...

Recent evidence demonstrates that the androgen receptor (AR) continues to influence prostate cancer growth despite medical therapies that reduce circulating androgen ligands to castrate levels and/or...

Decreased Androgen Receptor Levels and Receptor Function in Breast Cancer Contribute to the Failure of Response to Medroxyprogesterone Acetate (2005)

Buchanan, Grant, Birrell, Stephen N., Peters, Amelia A., Bianco-Miotto, Tina, Ramsay, Katrina, Cops, Elisa J., ...

Previously, we reported that androgen receptor (AR), but not estrogen receptor (ER) or progesterone receptor (PR), is predictive of response to the synthetic progestin, medroxyprogesterone acetate...

Mutation of the androgen receptor causes oncogenic transformation of the prostate (2005)

Han, Guangzhou, Buchanan, Grant, Ittmann, Michael, Harris, Jonathan M., Yu, Xiaoqing, DeMayo, Francesco J., ...

Recent evidence demonstrates that the androgen receptor (AR) continues to influence prostate cancer growth despite medical therapies that reduce circulating androgen ligands to castrate levels and/or...

Decreased Androgen Receptor Levels and Receptor Function in Breast Cancer Contribute to the Failure of Response to Medroxyprogesterone Acetate (2005)

Buchanan, Grant, Birrell, Stephen N., Peters, Amelia A., Bianco-Miotto, Tina, Ramsay, Katrina, Cops, Elisa J., ...

Previously, we reported that androgen receptor (AR), but not estrogen receptor (ER) or progesterone receptor (PR), is predictive of response to the synthetic progestin, medroxyprogesterone acetate...

Mutation of the androgen receptor causes oncogenic transformation of the prostate (2005)

Han, Guangzhou, Buchanan, Grant, Ittmann, Michael, Harris, Jonathan M., Yu, Xiaoqing, DeMayo, Francesco J., ...

Recent evidence demonstrates that the androgen receptor (AR) continues to influence prostate cancer growth despite medical therapies that reduce circulating androgen ligands to castrate levels and/or...

Decreased Androgen Receptor Levels and Receptor Function in Breast Cancer Contribute to the Failure of Response to Medroxyprogesterone Acetate (2005)

Buchanan, Grant, Birrell, Stephen N., Peters, Amelia A., Bianco-Miotto, Tina, Ramsay, Katrina, Cops, Elisa J., ...

Previously, we reported that androgen receptor (AR), but not estrogen receptor (ER) or progesterone receptor (PR), is predictive of response to the synthetic progestin, medroxyprogesterone acetate...

Mutation of the androgen receptor causes oncogenic transformation of the prostate (2005)

Han, Guangzhou, Buchanan, Grant, Ittmann, Michael, Harris, Jonathan M., Yu, Xiaoqing, DeMayo, Francesco J., ...

Recent evidence demonstrates that the androgen receptor (AR) continues to influence prostate cancer growth despite medical therapies that reduce circulating androgen ligands to castrate levels and/or...

Decreased Androgen Receptor Levels and Receptor Function in Breast Cancer Contribute to the Failure of Response to Medroxyprogesterone Acetate (2005)

Buchanan, Grant, Birrell, Stephen N., Peters, Amelia A., Bianco-Miotto, Tina, Ramsay, Katrina, Cops, Elisa J., ...

Previously, we reported that androgen receptor (AR), but not estrogen receptor (ER) or progesterone receptor (PR), is predictive of response to the synthetic progestin, medroxyprogesterone acetate...

Structural and functional consequences of glutamine tract variation in the androgen receptor (2004)

Buchanan, Grant, Yang, Miao, Cheong, Albert, Harris, Jonathan M., Irvine, Ryan A., Lambert, Paul F., ...

The androgen receptor (AR) gene contains a polymorphic trinucleotide repeat region, (CAG)n in its amino-terminal transactivation domain (NTD) that encodes a polyglutamine (polyQ) tract in the...

Structural and functional consequences of glutamine tract variation in the androgen receptor (2004)

Buchanan, Grant, Yang, Miao, Cheong, Albert, Harris, Jonathan M., Irvine, Ryan A., Lambert, Paul F., ...

The androgen receptor (AR) gene contains a polymorphic trinucleotide repeat region, (CAG)n, in its N-terminal transactivation domain (NTD) that encodes a polyglutamine (polyQ) tract in the receptor...

Structural and functional consequences of glutamine tract variation in the androgen receptor (2004)

Buchanan, Grant, Yang, Miao, Cheong, Albert, Harris, Jonathan M., Irvine, Ryan A., Lambert, Paul F., ...

The androgen receptor (AR) gene contains a polymorphic trinucleotide repeat region, (CAG)n in its amino-terminal transactivation domain (NTD) that encodes a polyglutamine (polyQ) tract in the...

Association between chronic fatigue syndrome and the corticosteroid-binding globulin gene ALA SER224 polymorphism (2004)

Torpy, David James, Bachmann, A. W., Gartside, M., Grice, J. E., Harris, Jonathan M., Clifton, Peter Marshall, ...

Chronic fatigue syndrome (CFS) is characterized by idiopathic fatigue of greater than 6 months' duration with postexertional exacerbation and many other symptoms. A trend toward relative...

Association between chronic fatigue syndrome and the corticosteroid-binding globulin gene ALA SER224 polymorphism (2004)

Torpy, David James, Bachmann, A. W., Gartside, M., Grice, J. E., Harris, Jonathan M., Clifton, Peter Marshall, ...

Chronic fatigue syndrome (CFS) is characterized by idiopathic fatigue of greater than 6 months' duration with postexertional exacerbation and many other symptoms. A trend toward relative...

Epitope map for a growth hormone receptor agonist monoclonal antibody, MAb 263 (2003)

Wan, Yu, Yuan, Zhi Zheng, Harris, Jonathan M., Brown, Richard, Waters, Michael J.

Monoclonal antibody (MAb) 263 is a widely used monoclonal antibody that recognizes the extracellular domain (ECD) of the GH receptor. It has been shown to act as a GH agonist both in vitro and in...

Epitope map for a growth hormone receptor agonist monoclonal antibody, MAb 263 (2003)

Wan, Yu, Zheng, Yuan-Zhi, Harris, Jonathan M., Brown, Richard, Waters, Michael J.

Monoclonal antibody (MAb) 263 is a widely used monoclonal antibody that recognizes the extracellular domain (ECD) of the GH receptor. It has been shown to act as a GH agonist both in vitro and in...

Characterization of the Retinoid Orphan-Related Receptor- Coactivator Binding Interface: A Structural Basis for Ligand-Independent Transcription (2002)

Harris, Jonathan M., Lau, Patrick, Chen, Shen Liang, Muscat, George E.

The retinoid orphan-related receptor- (ROR) is a member of the ROR subfamily of orphan receptors and acts as a constitutive activator of transcription in the absence of exogenous ligands. To...

Characterization of the Retinoid Orphan-Related Receptor- Coactivator Binding Interface: A Structural Basis for Ligand-Independent Transcription (2002)

Harris, Jonathan M., Lau, Patrick, Chen, Shen Liang, Muscat, George E.

The retinoid orphan-related receptor- (ROR) is a member of the ROR subfamily of orphan receptors and acts as a constitutive activator of transcription in the absence of exogenous ligands. To...

Characterization of the Retinoid Orphan-Related Receptor- Coactivator Binding Interface: A Structural Basis for Ligand-Independent Transcription (2002)

Harris, Jonathan M., Lau, Patrick, Chen, Shen Liang, Muscat, George E.

The retinoid orphan-related receptor- (ROR) is a member of the ROR subfamily of orphan receptors and acts as a constitutive activator of transcription in the absence of exogenous ligands. To...

Characterization of the Retinoid Orphan-Related Receptor- Coactivator Binding Interface: A Structural Basis for Ligand-Independent Transcription (2002)

Harris, Jonathan M., Lau, Patrick, Chen, Shen Liang, Muscat, George E.

The retinoid orphan-related receptor- (ROR) is a member of the ROR subfamily of orphan receptors and acts as a constitutive activator of transcription in the absence of exogenous ligands. To...

Characterization of the Retinoid Orphan-Related Receptor- Coactivator Binding Interface: A Structural Basis for Ligand-Independent Transcription (2002)

Harris, Jonathan M., Lau, Patrick, Chen, Shen Liang, Muscat, George E.

The retinoid orphan-related receptor- (ROR) is a member of the ROR subfamily of orphan receptors and acts as a constitutive activator of transcription in the absence of exogenous ligands. To...

Characterization of the Retinoid Orphan-Related Receptor- Coactivator Binding Interface: A Structural Basis for Ligand-Independent Transcription (2002)

Harris, Jonathan M., Lau, Patrick, Chen, Shen Liang, Muscat, George E.

The retinoid orphan-related receptor- (ROR) is a member of the ROR subfamily of orphan receptors and acts as a constitutive activator of transcription in the absence of exogenous ligands. To...

Characterization of the Retinoid Orphan-Related Receptor- Coactivator Binding Interface: A Structural Basis for Ligand-Independent Transcription (2002)

Harris, Jonathan M., Lau, Patrick, Chen, Shen Liang, Muscat, George E.

The retinoid orphan-related receptor- (ROR) is a member of the ROR subfamily of orphan receptors and acts as a constitutive activator of transcription in the absence of exogenous ligands. To...

Characterization of the Retinoid Orphan-Related Receptor- Coactivator Binding Interface: A Structural Basis for Ligand-Independent Transcription (2002)

Harris, Jonathan M., Lau, Patrick, Chen, Shen Liang, Muscat, George E.

The retinoid orphan-related receptor- (ROR) is a member of the ROR subfamily of orphan receptors and acts as a constitutive activator of transcription in the absence of exogenous ligands. To...

Characterization of the Retinoid Orphan-Related Receptor- Coactivator Binding Interface: A Structural Basis for Ligand-Independent Transcription (2002)

Harris, Jonathan M., Lau, Patrick, Chen, Shen Liang, Muscat, George E.

The retinoid orphan-related receptor- (ROR) is a member of the ROR subfamily of orphan receptors and acts as a constitutive activator of transcription in the absence of exogenous ligands. To...

A Survey of Sutainable Development : Social and Economic Dimenssions (2001)

Harris, Jonathan M. (ed. E Introd.), Goodwin, Neva R. (ed. E Introd.), Sen, Amartya K. (pról.)

Compilación de aproximadamente 70 textos acerca del desarrollo sustentable, en sus dimensiones social, ambiental y económica. El compendio atraviesa una amplia gama temática, entre la que se...

A Survey of Sutainable Development : Social and Economic Dimenssions / Ed. de J.M. Harris... [et al.] ; pról. de A.K. Sen ; introd. de J.M. Harris, N.R. Goodwin. (2001)

Harris, Jonathan M. (ed. E Introd.), Goodwin, Neva R. (ed. E Introd.), Sen, Amartya K. (pról.)

Compilación de aproximadamente 70 textos acerca del desarrollo sustentable, en sus dimensiones social, ambiental y económica. El compendio atraviesa una amplia gama temática, entre la que se...

Structure/function analysis of a dUTPase: catalytic mechanism of a potential chemotherapeutic target (1999)

Harris, Jonathan M., McIntosh, Evan M., Muscat, George E. O.

dUTP pyrophosphatase catalyses hydrolysis of deoxyuridine triphosphate (dUTP) to deoxyuridine monophosphate (dUMP) and inorganic pyrophosphate (PPi). Elimination of dUTP is vital since its...

Structure/function analysis of a dUTPase: catalytic mechanism of a potential chemotherapeutic target (1999)

Harris, Jonathan M., McIntosh, Evan M., Muscat, George E. O.

dUTP pyrophosphatase catalyses hydrolysis of deoxyuridine triphosphate (dUTP) to deoxyuridine monophosphate (dUMP) and inorganic pyrophosphate (PPi). Elimination of dUTP is vital since its...

Quantitation of tissue- and sex-specific induction of rat GSH transferase subunits by dietary 1,2-dithiole-3-thiones (1993)

Meyer, David J., Harris, Jonathan M., Gilmore, Kim S., Coles, Brian, Kensler, Thomas W., Ketterer, Brian

Male and female Sprague—Dawley rats were maintained for 5 days on control diet or diet containing 0.075% (w/w) 1,2–dithiole–3–thione (D3T) or...

Phosphorylation of the Pseudomonas aeruginosa Response Regulator AlgR Is Essential for Type IV Fimbria-Mediated Twitching Motility

Whitchurch, Cynthia B., Erova, Tatiana E., Emery, Jacqui A., Sargent, Jennifer L., Harris, Jonathan M., Semmler, Annalese B. T., ...

The response regulator AlgR is required for both alginate biosynthesis and type IV fimbria-mediated twitching motility in Pseudomonas aeruginosa. In this study, the roles of AlgR signal transduction...

Mutation of the androgen receptor causes oncogenic transformation of the prostate

Han, Guangzhou, Buchanan, Grant, Ittmann, Michael, Harris, Jonathan M., Yu, Xiaoqing, DeMayo, Francesco J., ...

Recent evidence demonstrates that the androgen receptor (AR) continues to influence prostate cancer growth despite medical therapies that reduce circulating androgen ligands to castrate levels and/or...

Phosphorylation of the Pseudomonas aeruginosa Response Regulator AlgR Is Essential for Type IV Fimbria-Mediated Twitching Motility

Whitchurch, Cynthia B., Erova, Tatiana E., Emery, Jacqui A., Sargent, Jennifer L., Harris, Jonathan M., Semmler, Annalese B. T., ...

The response regulator AlgR is required for both alginate biosynthesis and type IV fimbria-mediated twitching motility in Pseudomonas aeruginosa. In this study, the roles of AlgR signal transduction...

Mutation of the androgen receptor causes oncogenic transformation of the prostate

Han, Guangzhou, Buchanan, Grant, Ittmann, Michael, Harris, Jonathan M., Yu, Xiaoqing, DeMayo, Francesco J., ...

Recent evidence demonstrates that the androgen receptor (AR) continues to influence prostate cancer growth despite medical therapies that reduce circulating androgen ligands to castrate levels and/or...

03-03 "Reconciling Growth and Environment"

Jonathan M. Harris, Neva R. Goodwin

Macroeconomic theory and policy are strongly based on the assumption that economic growth is a fundamental goal. The environmental realities of the twenty- first century compel a reassessment of...

01-09 "Macroeconomic Policy and Sustainability"

Jonathan M. Harris

The trend in mainstream economic thought about macroeconomic policy has been towards minimalism. In the optimistic Keynesian phase of the 1960's, it was assumed that both fiscal and monetary policy...

"Basic Principles of Sustainable Development"

Jonathan M. Harris

This paper explores what a critical commentary on micro principles texts might look like, examining what is to be critiqued and how to do it.

Reconciling Growth and the Environment

Goodwin, Neva R., Harris, Jonathan M.

Macroeconomic theory and policy are strongly based on the assumption that economic growth is a fundamental goal. The environmental realities of the twenty- first century compel a reassessment of...

Agriculture in a Global Perspective

Harris, Jonathan M.

In the twenty-first century, it is evident that world agricultural systems will have to supply sufficient food for a population somewhere between 7.5 and 12 billion. Projections for world agriculture...