Jonathan Morton

Nitric Oxide deficiency promotes vascular side effects of cyclooxygenase inhibitors. (2006)

Anning, Peter Brian, Coles, Barbara, Morton, Jonathan, Wang, Haibin, Uddin, Jashim, Morrow, Jason D., ...

The cardiovascular safety of COX-2 selective and nonselective nonsteroidal anti-inflammatory drugs (NSAIDs) has recently been called into question. The factors that predispose to adverse events by...

Nitric oxide deficiency promotes vascular side effects of cyclooxygenase inhibitors

Anning, Peter B., Coles, Barbara, Morton, Jonathan, Wang, Haibin, Uddin, Jashim, Morrow, Jason D., ...

The cardiovascular safety of COX-2 selective and nonselective nonsteroidal anti-inflammatory drugs (NSAIDs) has recently been called into question. The factors that predispose to adverse events by...

CD59 or C3 are not requred for angiotensin II-dependent hypertension or hypertrophy in mice

Coles, Barbara, Lewis, Ruth, Anning, Peter B, Morton, Jonathan, Baalasubramanian, Sivasankar, Morgan, B Paul, ...

Complement is a major pro-inflammatory innate immune system whose serum activity correlates with systolic blood pressure in humans. To date, no studies using in vivo models have directly examined the...

Circulating neutrophils maintain physiological blood pressure by suppressing bacteria and IFNγ-dependent iNOS expression in the vasculature of healthy mice

Morton, Jonathan, Coles, Barbara, Wright, Kate, Gallimore, Awen, Morrow, Jason D., Terry, Erin S., ...

Whether leukocytes exert an influence on vascular function in vivo is not known. Here, genetic and pharmacologic approaches show that the absence of neutrophils leads to acute blood pressure...