Four-Gene Expression Ratio Test for Survival in Patients Undergoing Surgery for Mesothelioma (2009)
Gordon, Gavin J., Dong, Lingsheng, Yeap, Beow Y., Richards, William G., Glickman, Jonathan N., Edenfield, Heather, ...
Background Malignant pleural mesothelioma has few effective treatments, one being cytoreductive surgery. We previously developed a gene ratio test to predict outcome of malignant pleural mesothelioma...
Kawasaki, Takako, Nosho, Katsuhiko, Ohnishi, Mutsuko, Suemoto, Yuko, Glickman, Jonathan N, Chan, Andrew T, ...
Abstract Background Cyclooxygenase-2 (COX-2, PTGS2 ) plays an important role in colorectal carcinogenesis. COX-2 overexpression in colorectal cancer is inversely associated with microsatellite...
Chen, Xiaoxin, Qin, Rong, Liu, Ba, Ma, Yan, Su, Yinghao, Yang, Chung S, ...
Abstract Background In rats, esophagogastroduodenal anastomosis (EGDA) without concomitant chemical carcinogen treatment leads to gastroesophageal reflux disease, multilayered epithelium (MLE, a...
Nowak, Johannes, Weylandt, Karsten H., Habbel, Piet, Wang, Jingdong, Dignass, Axel, Glickman, Jonathan N., ...
Colorectal cancer (CRC) is the second leading cause of cancer deaths in USA. Anti-inflammatory drugs were shown to be effective in the prevention of CRC, supporting a link between inflammation and...
Shepard, Jennifer L., Amatruda, James F., Finkelstein, David, Ziai, James, Finley, K. Rose, Stern, Howard M., ...
Proper chromosome segregation is essential for maintenance of genomic integrity and instability resulting from failure of this process may contribute to cancer. Here, we demonstrate that a mutation...
HST.121 Gastroenterology, Fall 2002 (2002)
Carey, Martin C., Schapiro, Robert, Badizadegan, Kamran, Chung, Raymond T., Glickman, Jonathan N.
Presents the anatomy, physiology, biochemistry, biophysics, and bioengineering of the gastrointestinal tract and associated pancreatic, liver, and biliary systems. Emphasis on the molecular and...
HST.121 Gastroenterology, Fall 2002 (2002)
Carey, Martin C., Schapiro, Robert, Badizadegan, Kamran, Chung, Raymond T., Glickman, Jonathan N.
Presents the anatomy, physiology, biochemistry, biophysics, and bioengineering of the gastrointestinal tract and associated pancreatic, liver, and biliary systems. Emphasis on the molecular and...
Vascular tumors in livers with targeted inactivation of the von Hippel–Lindau tumor suppressor
Haase, Volker H., Glickman, Jonathan N., Socolovsky, Merav, Jaenisch, Rudolf
von Hippel–Lindau (VHL) disease is a pleomorphic familial tumor syndrome that is characterized by the development of highly vascularized tumors. Homozygous disruption of the VHL gene in mice...
Arita, Makoto, Yoshida, Masaru, Hong, Song, Tjonahen, Eric, Glickman, Jonathan N., Petasis, Nicos A., ...
Resolvin E1 (RvE1; 5S,12R,18R-trihydroxyeicosapentaenoic acid) is an antiinflammatory lipid mediator derived from omega-3 fatty acid eicosapentaenoic acid (EPA). At the local site of inflammation,...
A zebrafish bmyb mutation causes genome instability and increased cancer susceptibility
Shepard, Jennifer L., Amatruda, James F., Stern, Howard M., Subramanian, Aravind, Finkelstein, David, Ziai, James, ...
A major goal of cancer research has been to identify genes that contribute to cancer formation. The similar pathology between zebrafish and human tumors, as well as the past success of large-scale...
Gordon, Gavin J., Rockwell, Graham N., Jensen, Roderick V., Rheinwald, James G., Glickman, Jonathan N., Aronson, Joshua P., ...
Malignant pleural mesothelioma (MPM) is a highly lethal, poorly understood neoplasm that is typically associated with asbestos exposure. We performed transcriptional profiling using high-density...
Neonatal Fc receptor for IgG regulates mucosal immune responses to luminal bacteria
Yoshida, Masaru, Kobayashi, Kanna, Kuo, Timothy T., Bry, Lynn, Glickman, Jonathan N., Claypool, Steven M., ...
The neonatal Fc receptor for IgG (FcRn) plays a major role in regulating host IgG levels and transporting IgG and associated antigens across polarized epithelial barriers. Selective expression of...
Vascular tumors in livers with targeted inactivation of the von Hippel–Lindau tumor suppressor
Haase, Volker H., Glickman, Jonathan N., Socolovsky, Merav, Jaenisch, Rudolf
von Hippel–Lindau (VHL) disease is a pleomorphic familial tumor syndrome that is characterized by the development of highly vascularized tumors. Homozygous disruption of the VHL gene in mice...
Arita, Makoto, Yoshida, Masaru, Hong, Song, Tjonahen, Eric, Glickman, Jonathan N., Petasis, Nicos A., ...
Resolvin E1 (RvE1; 5S,12R,18R-trihydroxyeicosapentaenoic acid) is an antiinflammatory lipid mediator derived from omega-3 fatty acid eicosapentaenoic acid (EPA). At the local site of inflammation,...
A zebrafish bmyb mutation causes genome instability and increased cancer susceptibility
Shepard, Jennifer L., Amatruda, James F., Stern, Howard M., Subramanian, Aravind, Finkelstein, David, Ziai, James, ...
A major goal of cancer research has been to identify genes that contribute to cancer formation. The similar pathology between zebrafish and human tumors, as well as the past success of large-scale...
Neonatal Fc receptor for IgG regulates mucosal immune responses to luminal bacteria
Yoshida, Masaru, Kobayashi, Kanna, Kuo, Timothy T., Bry, Lynn, Glickman, Jonathan N., Claypool, Steven M., ...
The neonatal Fc receptor for IgG (FcRn) plays a major role in regulating host IgG levels and transporting IgG and associated antigens across polarized epithelial barriers. Selective expression of...
Gordon, Gavin J., Rockwell, Graham N., Jensen, Roderick V., Rheinwald, James G., Glickman, Jonathan N., Aronson, Joshua P., ...
Malignant pleural mesothelioma (MPM) is a highly lethal, poorly understood neoplasm that is typically associated with asbestos exposure. We performed transcriptional profiling using high-density...
A mutation in separase causes genome instability and increased susceptibility to epithelial cancer
Shepard, Jennifer L., Amatruda, James F., Finkelstein, David, Ziai, James, Finley, K. Rose, Stern, Howard M., ...
Proper chromosome segregation is essential for maintenance of genomic integrity and instability resulting from failure of this process may contribute to cancer. Here, we demonstrate that a mutation...
Kawasaki, Takako, Nosho, Katsuhiko, Ohnishi, Mutsuko, Suemoto, Yuko, Glickman, Jonathan N, Chan, Andrew T, ...
Specific Regulation of T Helper Cell 1–mediated Murine Colitis by CEACAM1
Iijima, Hideki, Neurath, Markus F., Nagaishi, Takashi, Glickman, Jonathan N., Nieuwenhuis, Edward E., Nakajima, Atsushi, ...
Carcinoembryonic antigen-related cellular adhesion molecule 1 (CEACAM1) is a cell surface molecule that has been proposed to negatively regulate T cell function. We have shown that CEACAM1 is...
Chen, Xiaoxin, Qin, Rong, Liu, Ba, Ma, Yan, Su, Yinghao, Yang, Chung S, ...
Mast cells are an essential hematopoietic component for polyp development
Gounaris, Elias, Erdman, Susan E., Restaino, Clifford, Gurish, Michael F., Friend, Daniel S., Gounari, Fotini, ...
It is generally agreed that most colon cancers develop from adenomatous polyps, and it is this fact on which screening strategies are based. Although there is overwhelming evidence to link intrinsic...
Transcriptome sequencing of malignant pleural mesothelioma tumors
Sugarbaker, David J., Richards, William G., Gordon, Gavin J., Dong, Lingsheng, De Rienzo, Assunta, Maulik, Gautam, ...
Cancers arise by the gradual accumulation of mutations in multiple genes. We now use shotgun pyrosequencing to characterize RNA mutations and expression levels unique to malignant pleural...