Jonathan R. S. Arch

Effects of (−)-RO363 at human atrial β-adrenoceptor subtypes, the human cloned β3-adrenoceptor and rodent intestinal β3-adrenoceptors

Molenaar, Peter, Sarsero, Doreen, Arch, Jonathan R S, Kelly, John, Henson, Sian M, Kaumann, Alberto J

Chronic treatment of patients with β-blockers causes atrial inotropic hyperresponsiveness through β2-adrenoceptors, 5-HT4 receptors and H2-receptors but apparently not through β1-adrenoceptors...

Do low-affinity states of β-adrenoceptors have roles in physiology and medicine?

Arch, Jonathan R S

The pharmacology once ascribed to the ‘β4-adrenoceptor' is now believed to be that of a low-affinity state of the β1-adrenoceptor. The β2-adrenoceptor may also have a low-affinity state or site,...