José L. Puente

Host–pathogen interactions: Host resistance factor Nramp1 up-regulates the expression of Salmonella pathogenicity island-2 virulence genes

Zaharik, Michelle L., Vallance, Bruce A., Puente, José L., Gros, Philippe, Finlay, B. Brett

Nramp1 (Natural resistance-associated macrophage protein-1; also known as Slc11a1) is a host resistance gene that provides protection against several intracellular pathogens, including Salmonella...

Dissecting virulence: Systematic and functional analyses of a pathogenicity island

Deng, Wanyin, Puente, José L., Gruenheid, Samantha, Li, Yuling, Vallance, Bruce A., Vázquez, Alejandra, ...

Bacterial pathogenicity islands (PAI) often encode both effector molecules responsible for disease and secretion systems that deliver these effectors to host cells. Human enterohemorrhagic...

A Positive Regulatory Loop Controls Expression of the Locus of Enterocyte Effacement-Encoded Regulators Ler and GrlA

Barba, Jeannette, Bustamante, Víctor H., Flores-Valdez, Mario A., Deng, Wanyin, Finlay, B. Brett, Puente, José L.

The formation of attaching and effacing (A/E) lesions on intestinal epithelial cells is an essential step in the pathogenesis of human enteropathogenic and enterohemorrhagic Escherichia coli and of...

Host–pathogen interactions: Host resistance factor Nramp1 up-regulates the expression of Salmonella pathogenicity island-2 virulence genes

Zaharik, Michelle L., Vallance, Bruce A., Puente, José L., Gros, Philippe, Finlay, B. Brett

Nramp1 (Natural resistance-associated macrophage protein-1; also known as Slc11a1) is a host resistance gene that provides protection against several intracellular pathogens, including Salmonella...

Dissecting virulence: Systematic and functional analyses of a pathogenicity island

Deng, Wanyin, Puente, José L., Gruenheid, Samantha, Li, Yuling, Vallance, Bruce A., Vázquez, Alejandra, ...

Bacterial pathogenicity islands (PAI) often encode both effector molecules responsible for disease and secretion systems that deliver these effectors to host cells. Human enterohemorrhagic...

A Positive Regulatory Loop Controls Expression of the Locus of Enterocyte Effacement-Encoded Regulators Ler and GrlA

Barba, Jeannette, Bustamante, Víctor H., Flores-Valdez, Mario A., Deng, Wanyin, Finlay, B. Brett, Puente, José L.

The formation of attaching and effacing (A/E) lesions on intestinal epithelial cells is an essential step in the pathogenesis of human enteropathogenic and enterohemorrhagic Escherichia coli and of...

Commensal and pathogenic Escherichia coli use a common pilus adherence factor for epithelial cell colonization

Rendón, María A., Saldaña, Zeus, Erdem, Ayşen L., Monteiro-Neto, Valério, Vázquez, Alejandra, Kaper, James B., ...

Enterohemorrhagic Escherichia coli (EHEC) O157:H7 is a food-borne pathogen that causes hemorrhagic colitis and the hemolytic uremic syndrome. Colonization of the human gut mucosa and production of...

HilD-mediated transcriptional cross-talk between SPI-1 and SPI-2

Bustamante, Víctor H., Martínez, Luary C., Santana, Francisco J., Knodler, Leigh A., Steele-Mortimer, Olivia, Puente, José L.

The acquisition of new genetic traits by horizontal gene transfer and their incorporation into preexisting regulatory networks have been essential events in the evolution of bacterial pathogens. An...