Joseph B. Bolen

A conditional form of Bruton's tyrosine kinase is sufficient to activate multiple downstream signaling pathways via PLC Gamma 2 in B cells (2001)

Tomlinson, Michael G, Woods, Douglas B, McMahon, Martin, Wahl, Matthew I, Witte, Owen N, Kurosaki, Tomohiro, ...

Abstract Background Bruton's tyrosine kinase (Btk) is essential for B cell development and function. Mutations of Btk elicit X-linked agammaglobulinemia in humans and X-linked immunodeficiency in the...

Cell mediated immune responses to Staphylococcus aureus in mice /--by Joseph B. Bolen. (1977)

Bolen, Joseph B., University Of Nebraska--Lincoln.--School Of Life Sciences.

Thesis--University of Nebraska--Lincoln.

A conditional form of Bruton's tyrosine kinase is sufficient to activate multiple downstream signaling pathways via PLC Gamma 2 in B cells

Tomlinson, Michael G, Woods, Douglas B, McMahon, Martin, Wahl, Matthew I, Witte, Owen N, Kurosaki, Tomohiro, ...

A conditional form of Bruton's tyrosine kinase is sufficient to activate multiple downstream signaling pathways via PLC Gamma 2 in B cells

Tomlinson, Michael G, Woods, Douglas B, McMahon, Martin, Wahl, Matthew I, Witte, Owen N, Kurosaki, Tomohiro, ...

Antitumor activity of MLN8054, an orally active small-molecule inhibitor of Aurora A kinase

Manfredi, Mark G., Ecsedy, Jeffrey A., Meetze, Kristan A., Balani, Suresh K., Burenkova, Olga, Chen, Wei, ...

Increased Aurora A expression occurs in a variety of human cancers and induces chromosomal abnormalities during mitosis associated with tumor initiation and progression. MLN8054 is a selective...