Genomic analysis of the mouse Legionella pneumophila susceptibility locus / (2001)
Thesis (Ph. D., Division of Medical Sciences (Genetics))--Harvard University, 2001.
Genomic Sequence Analysis of the Mouse Naip Gene Array (2000)
Endrizzi, Matthew G., Hadinoto, Vey, Growney, Joseph D., Miller, Webb, Dietrich, William F.
Growney, Joseph D., Dietrich, William F.
Prior genetic and physical mapping has shown that the Naip gene cluster on mouse chromosome 13D1-D3 contains a gene, Lgn1, that is responsible for determining the permissivity of ex vivo macrophages...
Genomic Sequence Analysis of the Mouse Naip Gene Array
Endrizzi, Matthew G., Hadinoto, Vey, Growney, Joseph D., Miller, Webb, Dietrich, William F.
A mouse locus called Lgn1 determines differences in macrophage permissiveness for the intracellular replication of Legionella pneumophila. The only regional candidate genes for this phenotype...
Growney, Joseph D., Dietrich, William F.
Prior genetic and physical mapping has shown that the Naip gene cluster on mouse chromosome 13D1-D3 contains a gene, Lgn1, that is responsible for determining the permissivity of ex vivo macrophages...
Genomic Sequence Analysis of the Mouse Naip Gene Array
Endrizzi, Matthew G., Hadinoto, Vey, Growney, Joseph D., Miller, Webb, Dietrich, William F.
A mouse locus called Lgn1 determines differences in macrophage permissiveness for the intracellular replication of Legionella pneumophila. The only regional candidate genes for this phenotype...
Loss of Runx1 perturbs adult hematopoiesis and is associated with a myeloproliferative phenotype
Growney, Joseph D., Shigematsu, Hirokazu, Li, Zhe, Lee, Benjamin H., Adelsperger, Jennifer, Rowan, Rebecca, ...
Homozygous loss of function of Runx1 (Runt-related transcription factor 1 gene) during murine development results in an embryonic lethal phenotype characterized by a complete lack of definitive...
Growney, Joseph D., Clark, Jennifer J., Adelsperger, Jennifer, Stone, Richard, Fabbro, Doriano, Griffin, James D., ...
Constitutively activated forms of the transmembrane receptor tyrosine kinase c-KIT have been associated with systemic mast cell disease, acute myeloid leukemia, and gastrointestinal stromal tumors....
Gotlib, Jason, Berubé, Caroline, Growney, Joseph D., Chen, Ching-Cheng, George, Tracy I., Williams, Christopher, ...
The majority of patients with systemic mast cell disease express the imatinib-resistant Asp816Val (D816V) mutation in the KIT receptor tyrosine kinase. Limited treatment options exist for aggressive...
Watarai, Masahisa, Derre, Isabelle, Kirby, James, Growney, Joseph D., Dietrich, William F., Isberg, Ralph R.
The products of the Legionella pneumophila dot/icm genes enable the bacterium to replicate within a macrophage vacuole. This study demonstrates that the Dot/Icm machinery promotes macropinocytotic...