Joseph Frankel

Printed in Great Britain © The Company of Biologists Limited 1987 Positional reorganization in compound janus cells of Tetrahymena thermophila (2008)

Joseph Frankel, E. Marlo Nelsen

The janus mutations of Tetrahymena thermophila convert the large-scale organization of the dorsal surface of the cell into a mirror-image of the ventral surface, which is characterized by a second,...

Macronuclear genome sequence of the ciliate Tetrahymena thermophila, a model eukaryote. (2006)

Eisen, Jonathan A, Coyne, Robert S, Wu, Martin, Wu, Dongying, Thiagarajan, Mathangi, Wortman, Jennifer R, ...

The ciliate Tetrahymena thermophila is a model organism for molecular and cellular biology. Like other ciliates, this species has separate germline and soma functions that are embodied by distinct...

Macronuclear Genome Sequence of the Ciliate Tetrahymena thermophila, a Model Eukaryote (2006)

Eisen, Jonathan A, Coyne, Robert S, Wu, Martin, Wu, Dongying, Thiagarajan, Mathangi, Wortman, Jennifer R, ...

The ciliate Tetrahymena thermophila is a model organism for molecular and cellular biology. Like other ciliates, this species has separate germline and soma functions that are embodied by distinct...

Macronuclear Genome Sequence of the Ciliate Tetrahymena thermophila, a Model Eukaryote (2006)

Jonathan A. Eisen, Robert S. Coyne, Martin Wu, Dongying Wu, Mathangi Thiagarajan, Jennifer R. Wortman, ...

The ciliate Tetrahymena thermophila is a model organism for molecular and cellular biology. Like other ciliates, this species has separate germline and soma functions that are embodied by distinct...

Macronuclear Genome Sequence of the Ciliate Tetrahymena thermophila, a Model Eukaryote (2006)

Eisen, Jonathan A., Coyne, Robert S., Wu, Martin, Wu, Dongying, Thiagarajan, Mathangi, Wortman, Jennifer R., ...

The ciliate Tetrahymena thermophila is a model organism for molecular and cellular biology. Like other ciliates, this species has separate germline and soma functions that are embodied by distinct...

Macronuclear Genome Sequence of the Ciliate Tetrahymena thermophila, a Model Eukaryote (2006)

Eisen, Jonathan A., Coyne, Robert S., Wu, Martin, Wu, Dongying, Thiagarajan, Mathangi, Wortman, Jennifer R., ...

The ciliate Tetrahymena thermophila is a model organism for molecular and cellular biology. Like other ciliates, this species has separate germline and soma functions that are embodied by distinct...

Nuclear and Cortical Regulation in Doublets of Paramecium: II. When and How do Two Cortical Domains Reorganize to One? (2001)

FRANCINE IFTODE, MALGORZATA PRAJER, JOSEPH FRANKEL

Homopolar doublets with twofold rotational symmetry were generated in Paramecium tetraurelia and in P. undecaurelia by electrofusion or by arrested conjugation. These doublets underwent a complex...

The Effects of Supraoptimal Temperatures on Population Growth and Cortical Patterning in Tetrahymena pyriformis and Tetrahymena thermophila: A Comparison (2001)

JOSEPH FRANKEL, E. MARLO NELSEN

In this investigation, we compare the multiplication rates and morphogenetic responses of the two most studied Tetrahymena species, T. pyriformis and T. thermophila, at supraoptimal temperatures....

An Evaluation of Hsp90 as a Mediator of Cortical Patterning in Tetrahymena (2001)

JOSEPH FRANKEL, NORMAN E. WILLIAMS, E. MARLO NELSEN, PATRICK J. KEELING

This study asks two questions: 1) whether Hsp90 is involved in the regulation of cortical patterning in Tetrahymena, and 2) if it is, whether specific defects in this regulation can be attributed to...

Cell Context-specific Effects of the β-Tubulin Glycylation Domain on Assembly and Size of Microtubular Organelles

Thazhath, Rupal, Jerka-Dziadosz, Maria, Duan, Jianming, Wloga, Dorota, Gorovsky, Martin A., Frankel, Joseph, ...

Tubulin glycylation is a posttranslational modification found in cells with cilia or flagella. The ciliate Tetrahymena has glycylation on ciliary and cortical microtubules. We showed previously that...

The Actin Gene ACT1 Is Required for Phagocytosis, Motility, and Cell Separation of Tetrahymena thermophila†

Williams, Norman E., Tsao, Che-Chia, Bowen, Josephine, Hehman, Gery L., Williams, Ruth J., Frankel, Joseph

A previously identified Tetrahymena thermophila actin gene (C. G. Cupples and R. E. Pearlman, Proc. Natl. Acad. Sci. USA 83:5160-5164, 1986), here called ACT1, was disrupted by insertion of a neo3...

Mutations Affecting Cell Division in TETRAHYMENA PYRIFORMIS . I. Selection and Genetic Analysis

Frankel, Joseph, Jenkins, Leslie M., Doerder, F. Paul, Nelsen, E. Marlo

Fourteen nitrosoguanidine-induced mutations that bring about temperature-sensitive morphological abnormalities resulting from a specific effect on cell division have been isolated as heterozygous...

Propagation of Cortical Differences in Tetrahymena

Frankel, Joseph

Progeny clones were derived from crosses arranged so that the number of ciliary meridians (corticotype) was unusually high in one partner, and normal in the other. An analysis of the propagation of...

Macronuclear Genome Sequence of the Ciliate Tetrahymena thermophila, a Model Eukaryote

Eisen, Jonathan A, Coyne, Robert S, Wu, Martin, Wu, Dongying, Thiagarajan, Mathangi, Wortman, Jennifer R, ...

The ciliate Tetrahymena thermophila is a model organism for molecular and cellular biology. Like other ciliates, this species has separate germline and soma functions that are embodied by distinct...

Cell Context-specific Effects of the β-Tubulin Glycylation Domain on Assembly and Size of Microtubular Organelles

Thazhath, Rupal, Jerka-Dziadosz, Maria, Duan, Jianming, Wloga, Dorota, Gorovsky, Martin A., Frankel, Joseph, ...

Tubulin glycylation is a posttranslational modification found in cells with cilia or flagella. The ciliate Tetrahymena has glycylation on ciliary and cortical microtubules. We showed previously that...

Mutations Affecting Cell Division in TETRAHYMENA PYRIFORMIS . I. Selection and Genetic Analysis

Frankel, Joseph, Jenkins, Leslie M., Doerder, F. Paul, Nelsen, E. Marlo

Fourteen nitrosoguanidine-induced mutations that bring about temperature-sensitive morphological abnormalities resulting from a specific effect on cell division have been isolated as heterozygous...

Propagation of Cortical Differences in Tetrahymena

Frankel, Joseph

Progeny clones were derived from crosses arranged so that the number of ciliary meridians (corticotype) was unusually high in one partner, and normal in the other. An analysis of the propagation of...

The Actin Gene ACT1 Is Required for Phagocytosis, Motility, and Cell Separation of Tetrahymena thermophila†

Williams, Norman E., Tsao, Che-Chia, Bowen, Josephine, Hehman, Gery L., Williams, Ruth J., Frankel, Joseph

A previously identified Tetrahymena thermophila actin gene (C. G. Cupples and R. E. Pearlman, Proc. Natl. Acad. Sci. USA 83:5160-5164, 1986), here called ACT1, was disrupted by insertion of a neo3...

Macronuclear Genome Sequence of the Ciliate Tetrahymena thermophila, a Model Eukaryote

Eisen, Jonathan A, Coyne, Robert S, Wu, Martin, Wu, Dongying, Thiagarajan, Mathangi, Wortman, Jennifer R, ...

The ciliate Tetrahymena thermophila is a model organism for molecular and cellular biology. Like other ciliates, this species has separate germline and soma functions that are embodied by distinct...

THE RELATIONSHIP BETWEEN DEOXYRIBONUCLEIC ACID REPLICATION AND CELL DIVISION IN HEAT-SYNCHRONIZED TETRAHYMENA

Jeffery, William R., Stuart, Kenneth D., Frankel, Joseph

The effect of supraoptimal temperature on macronuclear DNA synthesis in Tetrahymena was studied by radioautography during prolonged heat and heat-shock synchronization treatments. Prolonged heat...

REGULATION OF MICROTUBULES IN TETRAHYMENA : I. Electron Microscopy of Oral Replacement

Williams, Norman E., Frankel, Joseph

The coupled resorption and redifferentiation of oral structures which occurs in Tetrahymena pyriformis under conditions of amino acid deprivation has been studied by transmission electron microscopy....

ANALYSIS OF THE SCHEDULE OF DNA REPLICATION IN HEAT-SYNCHRONIZED TETRAHYMENA

Jeffery, William R., Frankel, Joseph, De Bault, Lawrence E., Jenkins, Leslie M.

The temporal schedule of DNA replication in heat-synchronized Tetrahymena was studied by autoradiographic and cytofluorometric methods. It was shown that some cells, which were synchronized by...