Joseph J. Y. Sung

Transgenic cyclooxygenase-2 expression and high salt enhanced susceptibility to chemical-induced gastric cancer development in mice (2008)

Leung, Wai K., Wu, Kai-chun, Wong, Christine Y. P., Cheng, Alfred S. L., Ching, Arthur K. K., Chan, Anthony W. H., ...

Cyclooxoygenase (COX)-2 overexpression is involved in gastric carcinogenesis. While high-salt intake is a known risk factor for gastric cancer development, we determined the effects of high salt on...

Increased β-catenin mRNA levels and mutational alterations of the APC and β-catenin gene are present in intestinal-type gastric cancer (2002)

Ebert,Matthias. P. A., Fei,Guo, Kahmann,Sabine, Müller,Oliver, Yu,Jun, Sung,Joseph J. Y., ...

beta-Catenin is critical for intercellular adhesion and also plays a role as a transcription activating protein in the Wnt signalling pathway. Increased protein levels and mutation of the...

Increased β-catenin mRNA levels and mutational alterations of the APC and β-catenin gene are present in intestinal-type gastric cancer (2002)

Ebert, Matthias. P. A., Fei, Guo, Kahmann, Sabine, Müller, Oliver, Yu, Jun, Sung, Joseph J. Y., ...

beta-Catenin is critical for intercellular adhesion and also plays a role as a transcription activating protein in the Wnt signalling pathway. Increased protein levels and mutation of the...

Increased {beta}-catenin mRNA levels and mutational alterations of the APC and {beta}-catenin gene are present in intestinal-type gastric cancer (2002)

Ebert, Matthias P.A., Fei, Guo, Kahmann, Sabine, Müller, Oliver, Yu, Jun, Sung, Joseph J.Y., ...

β-Catenin is critical for intercellular adhesion and also plays a role as a transcription activating protein in the Wnt signalling pathway. Increased protein levels and mutation of the β-catenin...

Intravenous ciprofloxacin as treatment for patients with acute suppurative cholangitis: a randomized, controlled clinical trial (1995)

Sung, Joseph J. Y., Lyon, Donald J., Suen, Roamy, Chung, S. C. Sydney, Co, Arsenio L., Cheng, Augustine F. B., ...

One hundred consecutive patients with acute suppurative cholangitis were randomized in a prospective, controlled clinical trial to receive either ciprofloxacin (200 mg bd iv) or triple therapy...

Microbial ecology of the binary system (1991)

Sung, Joseph J. Y.

Bibliography: p. 191-208.

Microbial ecology of the binary system (1991)

Sung, Joseph J. Y.

Bibliography: p. 191-208.

Comparison of Three Different Sensitive Assays for Hepatitis B Virus DNA in Monitoring of Responses to Antiviral Therapy

Chan, Henry L. Y., Leung, Nancy W. Y., Lau, Tracy C. M., Wong, May L., Sung, Joseph J. Y.

The aim of our study was to compare the performances of two new hepatitis B virus (HBV) DNA assays, a cross-linking assay (NAXCOR) and a hybrid-capture amplification assay (Digene), versus the widely...

Helicobacter pylori Heat Shock Protein A: Serologic Responses and Genetic Diversity

Ng, Enders K. W., Thompson, Stuart A., Pérez-Pérez, Guillermo I., Kansau, Imad, Van Der Ende, Arie, Labigne, Agnès, ...

Helicobacter pylori synthesizes an unusual GroES homolog, heat shock protein A (HspA). The present study was aimed at an assessment of the serological response to HspA in a group of Chinese patients...

Comparison of Two Rapid Whole-Blood Tests for Helicobacter pylori Infection in Chinese Patients

Leung, Wai Keung, Chan, Francis K. L., Falk, Matthew S., Suen, Roamy, Sung, Joseph J. Y.

Consecutive Chinese patients undergoing endoscopy for dyspepsia were tested for Helicobacter pylori infection by two rapid whole-blood tests: FlexPack HP (Abbott Laboratories) and Helisal One-Step...

Evaluation of WHO criteria for identifying patients with severe acute respiratory syndrome out of hospital: prospective observational study

Rainer, Timothy H, Cameron, Peter A, Smit, DeVilliers, Ong, Kim L, Hung, Alex Ng Wing, Nin, David Chan Po, ...

Objectives To determine the clinical and radiological features of severe acute respiratory syndrome (SARS) and to evaluate the accuracy of the World Health Organization's guidelines on defining cases...

Haematological manifestations in patients with severe acute respiratory syndrome: retrospective analysis

Wong, Raymond S M, Wu, Alan, To, K F, Lee, Nelson, Lam, Christopher W K, Wong, C K, ...

Objectives To evaluate the haematological findings of patients with severe acute respiratory syndrome (SARS).

Treating Helicobacter pylori infection after surgery is unnecessary

Lee, Y T, Chan, Francis K L, Sung, Joseph J Y

Reviews have to be fair and unbiased

Sung, Joseph J Y, Li, Philip K T, Sanderson, John E, Woo, Jean

Severe acute respiratory syndrome: Patients were epidemiologically linked

Chan-Yeung, Moira, Seto, Wing Hong, Sung, Joseph J Y

Eradication of Helicobacter pylori Prevents Recurrence of Ulcer After Simple Closure of Duodenal Ulcer Perforation: Randomized Controlled Trial

Ng, Enders K. W., Lam, Y. H., Sung, Joseph J. Y., Yung, M. Y., To, K. F., Chan, Angus C. W., ...

Combining aspirin with antithrombotic agents: Risk of bleeding is increased but can be minimised

Sung, Joseph J Y

Comparison of Three Different Sensitive Assays for Hepatitis B Virus DNA in Monitoring of Responses to Antiviral Therapy

Chan, Henry L. Y., Leung, Nancy W. Y., Lau, Tracy C. M., Wong, May L., Sung, Joseph J. Y.

The aim of our study was to compare the performances of two new hepatitis B virus (HBV) DNA assays, a cross-linking assay (NAXCOR) and a hybrid-capture amplification assay (Digene), versus the widely...

Helicobacter pylori Heat Shock Protein A: Serologic Responses and Genetic Diversity

Ng, Enders K. W., Thompson, Stuart A., Pérez-Pérez, Guillermo I., Kansau, Imad, Van Der Ende, Arie, Labigne, Agnès, ...

Helicobacter pylori synthesizes an unusual GroES homolog, heat shock protein A (HspA). The present study was aimed at an assessment of the serological response to HspA in a group of Chinese patients...

Comparison of Two Rapid Whole-Blood Tests for Helicobacter pylori Infection in Chinese Patients

Leung, Wai Keung, Chan, Francis K. L., Falk, Matthew S., Suen, Roamy, Sung, Joseph J. Y.

Consecutive Chinese patients undergoing endoscopy for dyspepsia were tested for Helicobacter pylori infection by two rapid whole-blood tests: FlexPack HP (Abbott Laboratories) and Helisal One-Step...

Evaluation of WHO criteria for identifying patients with severe acute respiratory syndrome out of hospital: prospective observational study

Rainer, Timothy H, Cameron, Peter A, Smit, DeVilliers, Ong, Kim L, Hung, Alex Ng Wing, Nin, David Chan Po, ...

Objectives To determine the clinical and radiological features of severe acute respiratory syndrome (SARS) and to evaluate the accuracy of the World Health Organization's guidelines on defining cases...

Haematological manifestations in patients with severe acute respiratory syndrome: retrospective analysis

Wong, Raymond S M, Wu, Alan, To, K F, Lee, Nelson, Lam, Christopher W K, Wong, C K, ...

Objectives To evaluate the haematological findings of patients with severe acute respiratory syndrome (SARS).

Treating Helicobacter pylori infection after surgery is unnecessary

Lee, Y T, Chan, Francis K L, Sung, Joseph J Y

Reviews have to be fair and unbiased

Sung, Joseph J Y, Li, Philip K T, Sanderson, John E, Woo, Jean

Severe acute respiratory syndrome: Patients were epidemiologically linked

Chan-Yeung, Moira, Seto, Wing Hong, Sung, Joseph J Y

Eradication of Helicobacter pylori Prevents Recurrence of Ulcer After Simple Closure of Duodenal Ulcer Perforation: Randomized Controlled Trial

Ng, Enders K. W., Lam, Y. H., Sung, Joseph J. Y., Yung, M. Y., To, K. F., Chan, Angus C. W., ...

Combining aspirin with antithrombotic agents: Risk of bleeding is increased but can be minimised

Sung, Joseph J Y

Cyclooxygenase-2 Expression in Helicobacter pylori-Associated Premalignant and Malignant Gastric Lesions

Sung, Joseph J. Y., Leung, Wai K., Go, Minnie Y. Y., To, Ka F., Cheng, Alfred S. L., Ng, Enders K. W., ...

Expression of cyclooxygenase-2 (COX-2) in various stages of the Helicobacter pylori-associated gastric carcinogenesis pathway has not been elucidated. We investigated the distribution and intensity...

High Prevalence of the CD14-159CC Genotype in Patients Infected with Severe Acute Respiratory Syndrome-Associated Coronavirus▿

Yuan, Fang F., Boehm, Ingrid, Chan, Paul K. S., Marks, Katherine, Tang, Julian W., Hui, David S. C., ...

To investigate whether genetic factors of innate immunity might influence susceptibility and/or progression in individuals infected with SARS, we evaluated the CD14 gene polymorphism in 198 Hong Kong...

Avian Influenza Virus A/HK/483/97(H5N1) NS1 Protein Induces Apoptosis in Human Airway Epithelial Cells▿

Lam, W. Y., Tang, Julian W., Yeung, Apple C. M., Chiu, Lawrence C. M., Sung, Joseph J. Y., Chan, Paul K. S.

Avian H5N1 influenza virus causes a remarkably severe disease in humans, with an overall case fatality rate of greater than 50%. Human influenza A viruses induce apoptosis in infected cells, which...

Sclerotherapy or Banding for Oesophageal Varices?

Sung, Joseph J. Y.

Genotype-Specific Genomic Markers Associated with Primary Hepatomas, Based on Complete Genomic Sequencing of Hepatitis B Virus▿

Sung, Joseph J. Y., Tsui, Stephen K. W., Tse, Chi-Hang, Ng, Eddie Y. T., Leung, Kwong-Sak, Lee, Kin-Hong, ...

We aimed to identify genomic markers in hepatitis B virus (HBV) that are associated with hepatocellular carcinoma (HCC) development by comparing the complete genomic sequences of HBVs among patients...

OPCML Is a Broad Tumor Suppressor for Multiple Carcinomas and Lymphomas with Frequently Epigenetic Inactivation

Cui, Yan, Ying, Ying, Van Hasselt, Andrew, Ng, Ka Man, Yu, Jun, Zhang, Qian, ...

Correction: OPCML Is a Broad Tumor Suppressor for Multiple Carcinomas and Lymphomas with Frequently Epigenetic Inactivation

Cui, Yan, Ying, Ying, Van Hasselt, Andrew, Ng, Ka Man, Yu, Jun, Zhang, Qian, ...

Genotype Distribution and Sequence Variation of Hepatitis E Virus, Hong Kong

Lam, Wai-Yip, Chan, Rickjason C.W., Sung, Joseph J.Y., Chan, Paul K.S.

Most acute cases of infection with hepatitis E virus (HEV) in Hong Kong were autochthonous, sporadic, and occurred in older adults. All except 1 isolate belonged to genotype 4; most were...