Disentangling molecular relationships with a causal inference test (2009)
Millstein, Joshua, Zhang, Bin, Zhu, Jun, Schadt, Eric E
Abstract Background There has been intense effort over the past couple of decades to identify loci underlying quantitative traits as a key step in the process of elucidating the etiology of complex...
Mapping the Genetic Architecture of Gene Expression in Human Liver (2008)
Eric E. Schadt, Cliona Molony, Eugene Chudin, Ke Hao, Xia Yang, Pek Y. Lum, ...
Genetic variants that are associated with common human diseases do not lead directly to disease, but instead act on intermediate, molecular phenotypes that in turn induce changes in higher-order...
Millstein, Joshua, Siegmund, Kimberly D, Conti, David V, Gauderman, W James
Abstract Simulated Genetic Analysis Workshop14 data were analyzed by jointly testing linkage and association and by accounting for epistasis using a candidate gene approach. Our group was unblinded...
Thesis (M.S.)--University of Southern California, 2005.
Salam, Muhammad T., Millstein, Joshua, Li, Yu-Fen, Lurmann, Frederick W., Margolis, Helene G., Gilliland, Frank D.
Exposures to ambient air pollutants have been associated with adverse birth outcomes. We investigated the effects of air pollutants on birth weight mediated by reduced fetal growth among term infants...
A Testing Framework for Identifying Susceptibility Genes in the Presence of Epistasis
Millstein, Joshua, Conti, David V., Gilliland, Frank D., Gauderman, W. James
An efficient testing strategy called the “focused interaction testing framework” (FITF) was developed to identify susceptibility genes involved in epistatic interactions for case-control studies...
Salam, Muhammad T., Millstein, Joshua, Li, Yu-Fen, Lurmann, Frederick W., Margolis, Helene G., Gilliland, Frank D.
Exposures to ambient air pollutants have been associated with adverse birth outcomes. We investigated the effects of air pollutants on birth weight mediated by reduced fetal growth among term infants...
A Testing Framework for Identifying Susceptibility Genes in the Presence of Epistasis
Millstein, Joshua, Conti, David V., Gilliland, Frank D., Gauderman, W. James
An efficient testing strategy called the “focused interaction testing framework” (FITF) was developed to identify susceptibility genes involved in epistatic interactions for case-control studies...
Millstein, Joshua, Siegmund, Kimberly D, Conti, David V, Gauderman, W James
Simulated Genetic Analysis Workshop14 data were analyzed by jointly testing linkage and association and by accounting for epistasis using a candidate gene approach. Our group was unblinded to the...
Mapping the Genetic Architecture of Gene Expression in Human Liver
Schadt, Eric E, Molony, Cliona, Chudin, Eugene, Hao, Ke, Yang, Xia, Lum, Pek Y, ...
Genetic variants that are associated with common human diseases do not lead directly to disease, but instead act on intermediate, molecular phenotypes that in turn induce changes in higher-order...
Health Effects of the 2003 Southern California Wildfires on Children
Künzli, Nino, Avol, Ed, Wu, Jun, Gauderman, W. James, Rappaport, Ed, Millstein, Joshua, ...
Rationale: In late October 2003, Southern California wildfires burned more than 3,000 km2. The wildfires produced heavy smoke that affected several communities participating in the University of...
Uncovering the Genetic Landscape for Multiple Sleep-Wake Traits
Winrow, Christopher J., Williams, Deanna L., Kasarskis, Andrew, Millstein, Joshua, Laposky, Aaron D., Yang, He S., ...
Despite decades of research in defining sleep-wake properties in mammals, little is known about the nature or identity of genes that regulate sleep, a fundamental behaviour that in humans occupies...