Joshua R. Fischer

Solving a sticky problem: new genetic approaches to host cell adhesion by the Lyme disease spirochete (2005)

Coburn, Jenifer, Fischer, Joshua R., Leong, John M.

The Lyme disease spirochetes, comprised of at least three closely related species, Borrelia burgdorferi, Borrelia garinii and Borrelia afzelii, are fascinating and enigmatic bacterial pathogens. They...

In Vitro CpG Methylation Increases the Transformation Efficiency of Borrelia burgdorferi Strains Harboring the Endogenous Linear Plasmid lp56▿

Chen, Qiang, Fischer, Joshua R., Benoit, Vivian M., Dufour, Nicholas P., Youderian, Philip, Leong, John M.

Borrelia burgdorferi is the causative agent of Lyme disease, the most common vector-borne illness in the Northern hemisphere. Low-passage-number infectious strains of B. burgdorferi exhibit extremely...