Joy En-Lin Tan

Stochastic pairing of Ig heavy and light chains frequently generates B cell antigen receptors that are subject to editing in vivo (2005)

Novobrantseva, Tatiana, Xu, Shengli, Tan, Joy En-Lin, Maruyama, Mitsuo, Schwers, Stephan, Pelanda, Roberta, ...

We examined the generation and selection of the B cell antibody repertoire through crossing of mice bearing distinct Ig heavy (H) and light (L) chain rearranged variable region transgenes. Ig gene...

Stochastic pairing of Ig heavy and light chains frequently generates B cell antigen receptors that are subject to editing in vivo (2005)

Novobrantseva, Tatiana, Xu, Shengli, Tan, Joy En-Lin, Maruyama, Mitsuo, Schwers, Stephan, Pelanda, Roberta, ...

We examined the generation and selection of the B cell antibody repertoire through crossing of mice bearing distinct Ig heavy (H) and light (L) chain rearranged variable region transgenes. Ig gene...

B cell development and activation defects resulting in xid-like immunodeficiency in BLNK/SLP-65-deficient mice (2000)

Xu, Shengli, Tan, Joy En-Lin, Wong, Esther Poh-Ying, Manickam, Arunkumar, Ponniah, Sathivel, Lam, Kong-Peng

Engagement of the B cell receptor (BCR) leads to the activation of tyrosine kinases and other signaling molecules that ultimately determine the type and magnitude of the B lymphocyte's cellular...

Cbp Deficiency Alters Csk Localization in Lipid Rafts but Does Not Affect T-Cell Development

Xu, Shengli, Huo, Jianxin, Tan, Joy En-Lin, Lam, Kong-Peng

The ubiquitously expressed transmembrane adaptor Csk-binding protein (Cbp) recruits Csk to lipid rafts, where the latter exerts its negative regulatory effect on the Src family of protein tyrosine...

Cbp Deficiency Alters Csk Localization in Lipid Rafts but Does Not Affect T-Cell Development

Xu, Shengli, Huo, Jianxin, Tan, Joy En-Lin, Lam, Kong-Peng

The ubiquitously expressed transmembrane adaptor Csk-binding protein (Cbp) recruits Csk to lipid rafts, where the latter exerts its negative regulatory effect on the Src family of protein tyrosine...