Joy X. Lei

A novel brain-enriched E3 ubiquitin ligase RNF182 is up regulated in the brains of Alzheimer's patients and targets ATP6V0C for degradation (2008)

Liu, Qing, Lei, Joy X, Sikorska, Marianna, Liu, Rugao

Abstract Background Alterations in multiple cellular pathways contribute to the development of chronic neurodegeneration such as a sporadic Alzheimer's disease (AD). These, in turn, involve changes...

Novel subtractive transcription-based amplification of mRNA (STAR) method and its application in search of rare and differentially expressed genes in AD brains (2006)

Liu, Qing, Sooknanan, Roy R, Malek, Lawrence T, Ribecco-Lutkiewicz, Maria, Lei, Joy X, Shen, Hui, ...

Abstract Background Alzheimer's disease (AD) is a complex disorder that involves multiple biological processes. Many genes implicated in these processes may be present in low abundance in the human...

Methodology article (2006)

Bmc Genomics, Joy X Lei, Hui Shen, Boleslaw Lach, P Roy Walker, Joel Martin, ...

Novel subtractive transcription-based amplification of mRNA (STAR) method and its application in search of rare and differentially expressed genes in AD brains