Juan Casas-Mollano

The MUT9p kinase phosphorylates histone H3 threonine 3 and is necessary for heritable epigenetic silencing in Chlamydomonas (2008)

Casas-Mollano, Juan, Jeong, Byeong-Ryool, Xu, Jianping, Moriyama, Hideaki, Cerutti, Heriberto D.

Changes in chromatin organization are emerging as key regulators in nearly every aspect of DNA-templated metabolism in eukaryotes. Histones undergo many, largely reversible, posttranslational...

SET3p monomethylates histone H3 on lysine 9 and is required for the silencing of tandemly repeated transgenes in Chlamydomonas (2007)

Casas-Mollano, Juan, Van Dijk, Karin, Eisenhart, John, Cerutti, Heriberto D.

SET domain-containing proteins of the SU(VAR)3-9 class are major regulators of heterochromatin in several eukaryotes, including mammals, insects, plants and fungi. The function of these polypeptides...

On the Origin and Functions of RNA-Mediated Silencing: From Protists to Man (2006)

Cerutti, Heriberto D., Casas-Mollano, Juan

Double-stranded RNA has been shown to induce gene silencing in diverse eukaryotes and by a variety of pathways. We have examined the taxonomic distribution and the phylogenetic relationship of key...