Pleiotropic hierarchies from high-dimensional phenotyping by (2008)
Florian Markowetz, Juby Jacob, Stefan Bentink, Rainer Spang
RNA interference
Jacob, Juby, Jentsch, Marcel, Kostka, Dennis, Bentink, Stefan, Spang, Rainer
Motivation: Molecular diagnostics aims at classifying diseases into clinically relevant sub-entities based on molecular characteristics. Typically, the entities are split into subgroups, which might...
Jacob, Juby, Jentsch, Marcel, Kostka, Dennis, Bentink, Stefan, Spang, Rainer
Motivation: Molecular diagnostics aims at classifying diseases into clinically relevant sub-entities based on molecular characteristics. Typically, the entities are split into subgroups, which might...
Analyzing gene perturbation screens with nested effects models in R and bioconductor (2008)
Fröhlich, Holger, Beißbarth, Tim, Tresch, Achim, Kostka, Dennis, Jacob, Juby, Spang, Rainer, ...
Summary: Nested effects models (NEMs) are a class of probabilistic models introduced to analyze the effects of gene perturbation screens visible in high-dimensional phenotypes like microarrays or...
Representation theory of association schemes / (2004)
Aachen, Techn. Hochsch., Diss., 2004 (Nicht für den Austausch).
Representation Theory of Association Schemes (2004)
Diese Arbeit wird motiviert durch die algebraische Behandlung von association schemes und ihres natürliches Auftretens in der Theorie der endlichen Permutationsgruppen. Die vorliegende Arbeit...
Degree granted by Dept. of Industrial Engineering, Cullen College of Engineering.
Anchang, Benedict, Sadeh, Mohammad J., Jacob, Juby, Tresch, Achim, Vlad, Marcel O., Oefner, Peter J., ...
Cellular decision making in differentiation, proliferation, or cell death is mediated by molecular signaling processes, which control the regulation and expression of genes. Vice versa, the...
Analyzing gene perturbation screens with nested effects models in R and bioconductor
Fröhlich, Holger, Beißbarth, Tim, Tresch, Achim, Kostka, Dennis, Jacob, Juby, Spang, Rainer, ...
Summary: Nested effects models (NEMs) are a class of probabilistic models introduced to analyze the effects of gene perturbation screens visible in high-dimensional phenotypes like microarrays or...