Judith A. Clements

Translating tissue engineering technology platforms into cancer research (2009)

Hutmacher, Dietmar W., Horch, Raymund E., Loessner, Daniela, Rizzi, Simone C., Sieh, Shirly, Reichert, Johannes C., ...

Technology platforms originally developed for tissue engineering applications produce valuable models that mimic three-dimensional (3D) tissue organization and function to enhance the understanding...

Direct progesterone receptor and indirect androgen receptor interactions with the Kallikrein-Related peptidase 4 gene promoter in breast and prostate cancer (2009)

Lai, John, Myers, Stephen A., Lawrence, Mitchell, Odorico, Dimitri M., Clements, Judith A.

Kallikrein 4 (KLK4) is a member of the human KLK gene family of serine proteases, many of which are implicated in hormone-dependent cancers. Like other KLKs, such as KLK3/PSA and KLK2, KLK4 gene...

Direct progesterone receptor and indirect androgen receptor interactions with the Kallikrein-Related peptidase 4 gene promoter in breast and prostate cancer (2009)

Lai, John, Myers, Stephen A., Lawrence, Mitchell, Odorico, Dimitri M., Clements, Judith A.

Kallikrein 4 (KLK4) is a member of the human KLK gene family of serine proteases, many of which are implicated in hormone-dependent cancers. Like other KLKs, such as KLK3/PSA and KLK2, KLK4 gene...

Direct progesterone receptor and indirect androgen receptor interactions with the Kallikrein-Related peptidase 4 gene promoter in breast and prostate cancer (2009)

Lai, John, Myers, Stephen A., Lawrence, Mitchell, Odorico, Dimitri M., Clements, Judith A.

Kallikrein 4 (KLK4) is a member of the human KLK gene family of serine proteases, many of which are implicated in hormone-dependent cancers. Like other KLKs, such as KLK3/PSA and KLK2, KLK4 gene...

Translating tissue engineering technology platforms into cancer research (2009)

Hutmacher, Dietmar W., Horch, Raymund E., Loessner, Daniela, Rizzi, Simone C., Sieh, Shirly, Reichert, Johannes C., ...

Technology platforms originally developed for tissue engineering applications produce valuable models that mimic three-dimensional (3D) tissue organization and function to enhance the understanding...

Direct progesterone receptor and indirect androgen receptor interactions with the kallikrein-related peptidase 4 gene promoter in breast and prostate cancer (2009)

Myers, Stephen A., Lai, John, Lawrence, Mitchell G., Odorico, Dimitri M., Clements, Judith A

Kallikrein 4 (KLK4) is a member of the human KLK gene family of serine proteases, many of which are implicated in hormone-dependent cancers. Like other KLKs, such as KLK3/PSA and KLK2, KLK4 gene...

Direct progesterone receptor and indirect androgen receptor interactions with the Kallikrein-Related peptidase 4 gene promoter in breast and prostate cancer (2009)

Lai, John, Myers, Stephen A., Lawrence, Mitchell, Odorico, Dimitri M., Clements, Judith A.

Kallikrein 4 (KLK4) is a member of the human KLK gene family of serine proteases, many of which are implicated in hormone-dependent cancers. Like other KLKs, such as KLK3/PSA and KLK2, KLK4 gene...

Translating tissue engineering technology platforms into cancer research (2009)

Hutmacher, Dietmar W., Horch, Raymund E., Loessner, Daniela, Rizzi, Simone C., Sieh, Shirly, Reichert, Johannes C., ...

Technology platforms originally developed for tissue engineering applications produce valuable models that mimic three-dimensional (3D) tissue organization and function to enhance the understanding...

Prostatic trypsin-like kallikrein-related peptidases (KLKs) and other prostate-expressed tryptic proteinases as regulators of signalling via proteinase-activated receptors (PARs) (2008)

Ramsay, Andrew J., Reid, Janet C., Adams, Mark N., Samaratunga, Hemamali, Dong, Ying, Clements, Judith A., ...

The prostate is a site of high expression of serine proteinases including members of the kallikrein-related peptidase (KLK) family, as well as other secreted and membrane-anchored serine proteinases....

Kallikrein-related peptidase 4 (KLK4) initiates intracellular signaling via protease-activated receptors (PARs). KLK4 and PAR-2 are co-expressed during prostate cancer progression (2008)

Ramsay, Andrew J., Dong, Ying, Hunt, Melanie L., Linn, MayLa, Samaratunga, Hemamali, Clements, Judith A., ...

Kallikrein-related peptidase 4 (KLK4) is one of the 15 members of the human KLK family and a trypsin-like, prostate cancer-associated serine protease. Signaling initiated by trypsin-like serine...

Kallikrein-related peptidase 4 (KLK4) initiates intracellular signaling via protease-activated receptors (PARs). KLK4 and PAR-2 are co-expressed during prostate cancer progression (2008)

Ramsay, Andrew J., Dong, Ying, Hunt, Melanie L., Linn, MayLa, Samaratunga, Hemamali, Clements, Judith A., ...

Kallikrein-related peptidase 4 (KLK4) is one of the 15 members of the human KLK family and a trypsin-like, prostate cancer-associated serine protease. Signaling initiated by trypsin-like serine...

A novel transcript from the KLKP1 gene is androgen regulated, down-regulated during prostate cancer progression and encodes the first non-serine protease identified from the human kallikrein gene locus (2008)

Kaushal, Aneel, Myers, Stephen A., Dong, Ying, Lai, John, Tan, Olivia L., Bui, Loan T., ...

BACKGROUND: The kallikrein-related (KLK) serine protease, prostate specific antigen is the current marker for prostate cancer (PCa). Other members of the KLK family are also emerging as potential...

A novel transcript from the KLKP1 gene is androgen regulated, down-regulated during prostate cancer progression and encodes the first non-serine protease identified from the human kallikrein gene locus (2008)

Kaushal, Aneel, Myers, Stephen A., Dong, Ying, Lai, John, Tan, Olivia L., Bui, Loan T., ...

BACKGROUND: The kallikrein-related (KLK) serine protease, prostate specific antigen is the current marker for prostate cancer (PCa). Other members of the KLK family are also emerging as potential...

Tissue-specific promoter utilisation of the kallikrein-related peptidase genes, KLK5 and KLK7, and cellular localisation of the encoded proteins suggest roles in exocrine pancreatic function (2008)

Dong, Ying, Matigian, Nick, Harvey, Tracey J., Samaratunga, Hemamali, Hooper, John D., Clements, Judith A.

Tissue kallikrein (kallikrein 1) was first identified in pancreas and is the namesake of the kallikrein-related peptidase (KLK) family. KLK1 and the other 14 members of the human KLK family are...

Tissue-specific promoter utilisation of the kallikrein-related peptidase genes, KLK5 and KLK7, and cellular localisation of the encoded proteins suggest roles in exocrine pancreatic function (2008)

Dong, Ying, Matigian, Nick, Harvey, Tracey J., Samaratunga, Hemamali, Hooper, John D., Clements, Judith A.

Tissue kallikrein (kallikrein 1) was first identified in pancreas and is the namesake of the kallikrein-related peptidase (KLK) family. KLK1 and the other 14 members of the human KLK family are...

Kallikrein-related peptidase 4 (KLK4) initiates intracellular signaling via protease-activated receptors (PARs). KLK4 and PAR-2 are co-expressed during prostate cancer progression (2008)

Ramsay, Andrew J., Dong, Ying, Hunt, Melanie L., Linn, MayLa, Samaratunga, Hemamali, Clements, Judith A., ...

Kallikrein-related peptidase 4 (KLK4) is one of the 15 members of the human KLK family and a trypsin-like, prostate cancer-associated serine protease. Signaling initiated by trypsin-like serine...

A novel transcript from the KLKP1 gene is androgen regulated, down-regulated during prostate cancer progression and encodes the first non-serine protease identified from the human kallikrein gene locus (2008)

Kaushal, Aneel, Myers, Stephen A., Dong, Ying, Lai, John, Tan, Olivia L., Bui, Loan T., ...

BACKGROUND: The kallikrein-related (KLK) serine protease, prostate specific antigen is the current marker for prostate cancer (PCa). Other members of the KLK family are also emerging as potential...

Tissue-specific promoter utilisation of the kallikrein-related peptidase genes, KLK5 and KLK7, and cellular localisation of the encoded proteins suggest roles in exocrine pancreatic function (2008)

Dong, Ying, Matigian, Nick, Harvey, Tracey J., Samaratunga, Hemamali, Hooper, John D., Clements, Judith A.

Tissue kallikrein (kallikrein 1) was first identified in pancreas and is the namesake of the kallikrein-related peptidase (KLK) family. KLK1 and the other 14 members of the human KLK family are...

Kallikrein-related peptidase 4 (KLK4) initiates intracellular signaling via protease-activated receptors (PARs). KLK4 and PAR-2 are co-expressed during prostate cancer progression (2008)

Ramsay, Andrew J., Dong, Ying, Hunt, Melanie L., Linn, MayLa, Samaratunga, Hemamali, Clements, Judith A., ...

Kallikrein-related peptidase 4 (KLK4) is one of the 15 members of the human KLK family and a trypsin-like, prostate cancer-associated serine protease. Signaling initiated by trypsin-like serine...

A novel transcript from the KLKP1 gene is androgen regulated, down-regulated during prostate cancer progression and encodes the first non-serine protease identified from the human kallikrein gene locus (2008)

Kaushal, Aneel, Myers, Stephen A., Dong, Ying, Lai, John, Tan, Olivia L., Bui, Loan T., ...

BACKGROUND: The kallikrein-related (KLK) serine protease, prostate specific antigen is the current marker for prostate cancer (PCa). Other members of the KLK family are also emerging as potential...

Tissue-specific promoter utilisation of the kallikrein-related peptidase genes, KLK5 and KLK7, and cellular localisation of the encoded proteins suggest roles in exocrine pancreatic function (2008)

Dong, Ying, Matigian, Nick, Harvey, Tracey J., Samaratunga, Hemamali, Hooper, John D., Clements, Judith A.

Tissue kallikrein (kallikrein 1) was first identified in pancreas and is the namesake of the kallikrein-related peptidase (KLK) family. KLK1 and the other 14 members of the human KLK family are...

Kallikrein-related peptidase 4 (KLK4) initiates intracellular signaling via protease-activated receptors (PARs). KLK4 and PAR-2 are co-expressed during prostate cancer progression (2008)

Ramsay, Andrew J., Dong, Ying, Hunt, Melanie L., Linn, MayLa, Samaratunga, Hemamali, Clements, Judith A., ...

Kallikrein-related peptidase 4 (KLK4) is one of the 15 members of the human KLK family and a trypsin-like, prostate cancer-associated serine protease. Signaling initiated by trypsin-like serine...

A novel transcript from the KLKP1 gene is androgen regulated, down-regulated during prostate cancer progression and encodes the first non-serine protease identified from the human kallikrein gene locus (2008)

Kaushal, Aneel, Myers, Stephen A., Dong, Ying, Lai, John, Tan, Olivia L., Bui, Loan T., ...

BACKGROUND: The kallikrein-related (KLK) serine protease, prostate specific antigen is the current marker for prostate cancer (PCa). Other members of the KLK family are also emerging as potential...

Tissue-specific promoter utilisation of the kallikrein-related peptidase genes, KLK5 and KLK7, and cellular localisation of the encoded proteins suggest roles in exocrine pancreatic function (2008)

Dong, Ying, Matigian, Nick, Harvey, Tracey J., Samaratunga, Hemamali, Hooper, John D., Clements, Judith A.

Tissue kallikrein (kallikrein 1) was first identified in pancreas and is the namesake of the kallikrein-related peptidase (KLK) family. KLK1 and the other 14 members of the human KLK family are...

Prostatic trypsin-like kallikrein-related peptidases (KLKs) and other prostate-expressed tryptic proteinases as regulators of signalling via proteinase-activated receptors (PARs) (2008)

Ramsay, Andrew J., Reid, Janet C., Adams, Mark N., Samaratunga, Hemamali, Dong, Ying, Clements, Judith A., ...

The prostate is a site of high expression of serine proteinases including members of the kallikrein-related peptidase (KLK) family, as well as other secreted and membrane-anchored serine proteinases....

Kallikrein-related peptidase 4 (KLK4) initiates intracellular signaling via protease-activated receptors (PARs). KLK4 and PAR-2 are co-expressed during prostate cancer progression (2008)

Ramsay, Andrew J., Dong, Ying, Hunt, Melanie L., Linn, MayLa, Samaratunga, Hemamali, Clements, Judith A., ...

Kallikrein-related peptidase 4 (KLK4) is one of the 15 members of the human KLK family and a trypsin-like, prostate cancer-associated serine protease. Signaling initiated by trypsin-like serine...

A novel transcript from the KLKP1 gene is androgen regulated, down-regulated during prostate cancer progression and encodes the first non-serine protease identified from the human kallikrein gene locus (2008)

Kaushal, Aneel, Myers, Stephen A., Dong, Ying, Lai, John, Tan, Olivia L., Bui, Loan T., ...

BACKGROUND: The kallikrein-related (KLK) serine protease, prostate specific antigen is the current marker for prostate cancer (PCa). Other members of the KLK family are also emerging as potential...

Tissue-specific promoter utilisation of the kallikrein-related peptidase genes, KLK5 and KLK7, and cellular localisation of the encoded proteins suggest roles in exocrine pancreatic function (2008)

Dong, Ying, Matigian, Nick, Harvey, Tracey J., Samaratunga, Hemamali, Hooper, John D., Clements, Judith A.

Tissue kallikrein (kallikrein 1) was first identified in pancreas and is the namesake of the kallikrein-related peptidase (KLK) family. KLK1 and the other 14 members of the human KLK family are...

Prostatic trypsin-like kallikrein-related peptidases (KLKs) and other prostate-expressed tryptic proteinases as regulators of signalling via proteinase-activated receptors (PARs) (2008)

Ramsay, Andrew J., Reid, Janet C., Adams, Mark N., Samaratunga, Hemamali, Dong, Ying, Clements, Judith A., ...

The prostate is a site of high expression of serine proteinases including members of the kallikrein-related peptidase (KLK) family, as well as other secreted and membrane-anchored serine proteinases....

A Novel Transcript From the KLKP1 Gene Is Androgen Regulated, Down-Regulated During Prostate Cancer Progression and Encodes the First Non-Serine Protease Identified From the Human Kallikrein Gene Locus (2008)

Myers, Stephen A., Kaushal, Aneel, Dong, Ying, Lai, John, Tan, Olivia L., Bui, Loan T., ...

BACKGROUND. The kallikrein-related (KLK) serine protease, prostate specific antigen is the current marker for prostate cancer (PCa). Other members of theKLKfamily are also emerging as potential...

A Novel Transcript From the KLKP1 Gene Is Androgen Regulated, Down-Regulated During Prostate Cancer Progression and Encodes the First Non-Serine Protease Identified From the Human Kallikrein Gene Locus (2008)

Myers, Stephen A., Kaushal, Aneel, Dong, Ying, Lai, John, Tan, Olivia L., Bui, Loan T., ...

BACKGROUND. The kallikrein-related (KLK) serine protease, prostate specific antigen is the current marker for prostate cancer (PCa). Other members of theKLKfamily are also emerging as potential...

Kallikrein-related peptidase 4 (KLK4) initiates intracellular signaling via protease-activated receptors (PARs). KLK4 and PAR-2 are co-expressed during prostate cancer progression (2008)

Ramsay, Andrew J., Dong, Ying, Hunt, Melanie L., Linn, MayLa, Samaratunga, Hemamali, Clements, Judith A., ...

Kallikrein-related peptidase 4 (KLK4) is one of the 15 members of the human KLK family and a trypsin-like, prostate cancer-associated serine protease. Signaling initiated by trypsin-like serine...

A novel transcript from the KLKP1 gene is androgen regulated, down-regulated during prostate cancer progression and encodes the first non-serine protease identified from the human kallikrein gene locus (2008)

Kaushal, Aneel, Myers, Stephen A., Dong, Ying, Lai, John, Tan, Olivia L., Bui, Loan T., ...

BACKGROUND: The kallikrein-related (KLK) serine protease, prostate specific antigen is the current marker for prostate cancer (PCa). Other members of the KLK family are also emerging as potential...

Tissue-specific promoter utilisation of the kallikrein-related peptidase genes, KLK5 and KLK7, and cellular localisation of the encoded proteins suggest roles in exocrine pancreatic function (2008)

Dong, Ying, Matigian, Nick, Harvey, Tracey J., Samaratunga, Hemamali, Hooper, John D., Clements, Judith A.

Tissue kallikrein (kallikrein 1) was first identified in pancreas and is the namesake of the kallikrein-related peptidase (KLK) family. KLK1 and the other 14 members of the human KLK family are...

Prostatic trypsin-like kallikrein-related peptidases (KLKs) and other prostate-expressed tryptic proteinases as regulators of signalling via proteinase-activated receptors (PARs) (2008)

Ramsay, Andrew J., Reid, Janet C., Adams, Mark N., Samaratunga, Hemamali, Dong, Ying, Clements, Judith A., ...

The prostate is a site of high expression of serine proteinases including members of the kallikrein-related peptidase (KLK) family, as well as other secreted and membrane-anchored serine proteinases....

Kallikrein-related peptidase 4 (KLK4) initiates intracellular signaling via protease-activated receptors (PARs). KLK4 and PAR-2 are co-expressed during prostate cancer progression (2008)

Ramsay, Andrew J., Dong, Ying, Hunt, Melanie L., Linn, MayLa, Samaratunga, Hemamali, Clements, Judith A., ...

Kallikrein-related peptidase 4 (KLK4) is one of the 15 members of the human KLK family and a trypsin-like, prostate cancer-associated serine protease. Signaling initiated by trypsin-like serine...

A novel transcript from the KLKP1 gene is androgen regulated, down-regulated during prostate cancer progression and encodes the first non-serine protease identified from the human kallikrein gene locus (2008)

Kaushal, Aneel, Myers, Stephen A., Dong, Ying, Lai, John, Tan, Olivia L., Bui, Loan T., ...

BACKGROUND: The kallikrein-related (KLK) serine protease, prostate specific antigen is the current marker for prostate cancer (PCa). Other members of the KLK family are also emerging as potential...

Tissue-specific promoter utilisation of the kallikrein-related peptidase genes, KLK5 and KLK7, and cellular localisation of the encoded proteins suggest roles in exocrine pancreatic function (2008)

Dong, Ying, Matigian, Nick, Harvey, Tracey J., Samaratunga, Hemamali, Hooper, John D., Clements, Judith A.

Tissue kallikrein (kallikrein 1) was first identified in pancreas and is the namesake of the kallikrein-related peptidase (KLK) family. KLK1 and the other 14 members of the human KLK family are...

Prostatic trypsin-like kallikrein-related peptidases (KLKs) and other prostate-expressed tryptic proteinases as regulators of signalling via proteinase-activated receptors (PARs) (2008)

Ramsay, Andrew J., Reid, Janet C., Adams, Mark N., Samaratunga, Hemamali, Dong, Ying, Clements, Judith A., ...

The prostate is a site of high expression of serine proteinases including members of the kallikrein-related peptidase (KLK) family, as well as other secreted and membrane-anchored serine proteinases....

PSA/KLK3 AREI promoter polymorphism alters androgen receptor binding and is associated with prostate cancer susceptibility (2007)

Lai, John, Kedda, Mary-Anne, Hinze, Kimberly E., Smith, Robert L. G., Yaxley, John, Spurdle, Amanda B., ...

The proximal promoter of the kallikrein-related peptidase 3 gene (KLK3/PSA) contains a single-nucleotide polymorphism (G-158A) located within the second canonical half-site for the prostate-specific...

PSA/KLK3 AREI promoter polymorphism alters androgen receptor binding and is associated with prostate cancer susceptibility (2007)

Lai, John, Kedda, Mary-Anne, Hinze, Kimberly E., Smith, Robert L. G., Yaxley, John, Spurdle, Amanda B., ...

The proximal promoter of the kallikrein-related peptidase 3 gene (KLK3/PSA) contains a single-nucleotide polymorphism (G-158A) located within the second canonical half-site for the prostate-specific...

PSA/KLK3 AREI promoter polymorphism alters androgen receptor binding and is associated with prostate cancer susceptibility (2007)

Lai, John, Kedda, Mary-Anne, Hinze, Kimberly, Smith, Robert L.G., Yaxley, John, Spurdle, Amanda B., ...

The proximal promoter of the kallikrein-related peptidase 3 gene (KLK3/PSA) contains a single-nucleotide polymorphism (G-158A) located within the second canonical half-site for the prostate-specific...

Bone and prostate cancer cell interactions in metastatic prostate cancer (2007)

Vela, Ian, Gregory, Laura S., Gardiner, Edith M., Clements, Judith A., Nicol, David L.

The interplay in prostate cancer bone metastases between the 'seed' (the prostate cancer cells) and the 'soil' (the bone microenvironment) has been increasingly recognized as integral to the...

Bone and prostate cancer cell interactions in metastatic prostate cancer (2007)

Vela, Ian, Gregory, Laura S., Gardiner, Edith M., Clements, Judith A., Nicol, David L.

The interplay in prostate cancer bone metastases between the 'seed' (the prostate cancer cells) and the 'soil' (the bone microenvironment) has been increasingly recognized as integral to the...

Bone and prostate cancer cell interactions in metastatic prostate cancer (2007)

Vela, Ian, Gregory, Laura, Gardiner, Edith M., Clements, Judith A., Nicol, David L.

The interplay in prostate cancer bone metastases between the ‘seed’ (the prostatecancer cells) and the ‘soil’ (the bone microenvironment) has been increasinglyrecognized as integral to the...

Bone and prostate cancer cell interactions in metastatic prostate cancer (2007)

Vela, Ian, Gregory, Laura S., Gardiner, Edith M., Clements, Judith A., Nicol, David L.

The interplay in prostate cancer bone metastases between the 'seed' (the prostate cancer cells) and the 'soil' (the bone microenvironment) has been increasingly recognized as integral to the...

PSA/KLK3 AREI promoter polymorphism alters androgen receptor binding and is associated with prostate cancer susceptibility (2007)

Lai, John, Kedda, Mary-Anne, Hinze, Kimberly E., Smith, Robert L. G., Yaxley, John, Spurdle, Amanda B., ...

The proximal promoter of the kallikrein-related peptidase 3 gene (KLK3/PSA) contains a single-nucleotide polymorphism (G-158A) located within the second canonical half-site for the prostate-specific...

Bone and prostate cancer cell interactions in metastatic prostate cancer (2007)

Vela, Ian, Gregory, Laura S., Gardiner, Edith M., Clements, Judith A., Nicol, David L.

The interplay in prostate cancer bone metastases between the 'seed' (the prostate cancer cells) and the 'soil' (the bone microenvironment) has been increasingly recognized as integral to the...

PSA/KLK3 AREI promoter polymorphism alters androgen receptor binding and is associated with prostate cancer susceptibility (2007)

Lai, John, Kedda, Mary-Anne, Hinze, Kimberly E., Smith, Robert L. G., Yaxley, John, Spurdle, Amanda B., ...

The proximal promoter of the kallikrein-related peptidase 3 gene (KLK3/PSA) contains a single-nucleotide polymorphism (G-158A) located within the second canonical half-site for the prostate-specific...

Bone and prostate cancer cell interactions in metastatic prostate cancer (2007)

Vela, Ian, Gregory, Laura S., Gardiner, Edith M., Clements, Judith A., Nicol, David L.

The interplay in prostate cancer bone metastases between the 'seed' (the prostate cancer cells) and the 'soil' (the bone microenvironment) has been increasingly recognized as integral to the...

PSA/KLK3 AREI promoter polymorphism alters androgen receptor binding and is associated with prostate cancer susceptibility (2007)

Lai, John, Kedda, Mary-Anne, Hinze, Kimberly E., Smith, Robert L. G., Yaxley, John, Spurdle, Amanda B., ...

The proximal promoter of the kallikrein-related peptidase 3 gene (KLK3/PSA) contains a single-nucleotide polymorphism (G-158A) located within the second canonical half-site for the prostate-specific...

Bone and prostate cancer cell interactions in metastatic prostate cancer (2007)

Vela, Ian, Gregory, Laura S., Gardiner, Edith M., Clements, Judith A., Nicol, David L.

The interplay in prostate cancer bone metastases between the 'seed' (the prostate cancer cells) and the 'soil' (the bone microenvironment) has been increasingly recognized as integral to the...

PSA/KLK3 AREI promoter polymorphism alters androgen receptor binding and is associated with prostate cancer susceptibility (2007)

Lai, John, Kedda, Mary-Anne, Hinze, Kimberly E., Smith, Robert L. G., Yaxley, John, Spurdle, Amanda B., ...

The proximal promoter of the kallikrein-related peptidase 3 gene (KLK3/PSA) contains a single-nucleotide polymorphism (G-158A) located within the second canonical half-site for the prostate-specific...

Kallikrein 4 Is a Potential Mediator of Cellular Interactions Between Cancer Cells and Osteoblasts in Metastatic Prostate Cancer (2007)

Gao, Jin, Collard, Rachael L., Bui, Loan, Herington, Adrian C., Nicol, David L., Clements, Judith A.

BACKGROUND. Prostate cancer (PCa) and bone cell interactions are critical in the metastatic phase. Kallikrein 4 (KLK4/hK4) is expressed in both PCa and mineralized tissues. We determined if KLK4/hK4...

Kallikrein 4 Is a Potential Mediator of Cellular Interactions Between Cancer Cells and Osteoblasts in Metastatic Prostate Cancer (2007)

Gao, Jin, Collard, Rachael L., Bui, Loan, Herington, Adrian C., Nicol, David L., Clements, Judith A.

BACKGROUND. Prostate cancer (PCa) and bone cell interactions are critical in the metastatic phase. Kallikrein 4 (KLK4/hK4) is expressed in both PCa and mineralized tissues. We determined if KLK4/hK4...

Kallikrein 4 Is a Potential Mediator of Cellular Interactions Between Cancer Cells and Osteoblasts in Metastatic Prostate Cancer (2007)

Gao, Jin, Collard, Rachael L., Bui, Loan, Herington, Adrian C., Nicol, David L., Clements, Judith A.

BACKGROUND. Prostate cancer (PCa) and bone cell interactions are critical in the metastatic phase. Kallikrein 4 (KLK4/hK4) is expressed in both PCa and mineralized tissues. We determined if KLK4/hK4...

Bone and prostate cancer cell interactions in metastatic prostate cancer (2007)

Vela, Ian, Gregory, Laura S., Gardiner, Edith M., Clements, Judith A., Nicol, David L.

The interplay in prostate cancer bone metastases between the 'seed' (the prostate cancer cells) and the 'soil' (the bone microenvironment) has been increasingly recognized as integral to the...

PSA/KLK3 AREI promoter polymorphism alters androgen receptor binding and is associated with prostate cancer susceptibility (2007)

Lai, John, Kedda, Mary-Anne, Hinze, Kimberly E., Smith, Robert L. G., Yaxley, John, Spurdle, Amanda B., ...

The proximal promoter of the kallikrein-related peptidase 3 gene (KLK3/PSA) contains a single-nucleotide polymorphism (G-158A) located within the second canonical half-site for the prostate-specific...

Bone and prostate cancer cell interactions in metastatic prostate cancer (2007)

Vela, Ian, Gregory, Laura S., Gardiner, Edith M., Clements, Judith A., Nicol, David L.

The interplay in prostate cancer bone metastases between the 'seed' (the prostate cancer cells) and the 'soil' (the bone microenvironment) has been increasingly recognized as integral to the...

PSA/KLK3 AREI promoter polymorphism alters androgen receptor binding and is associated with prostate cancer susceptibility (2007)

Lai, John, Kedda, Mary-Anne, Hinze, Kimberly E., Smith, Robert L. G., Yaxley, John, Spurdle, Amanda B., ...

The proximal promoter of the kallikrein-related peptidase 3 gene (KLK3/PSA) contains a single-nucleotide polymorphism (G-158A) located within the second canonical half-site for the prostate-specific...

PSA/KLK3 AREI promoter polymorphism alters androgen receptor binding and is associated with prostate cancer susceptibility (2006)

Lai, John, Kedda, Mary-Anne, Hinze, Kimberly, Smith, Robert LG, Yaxley, John, Spurdle, Amanda B, ...

The proximal promoter of the kallikrein-related peptidase 3 gene (KLK3/PSA) contains a single nucleotide polymorphism (G-158A) located within the second canonical half-site for the PSA androgen...

PSA/KLK3 AREI promoter polymorphism alters androgen receptor binding and is associated with prostate cancer susceptibility (2006)

Lai, John, Kedda, Mary-Anne, Hinze, Kimberly, Smith, Robert L. G., Yaxley, John, Spurdle, Amanda B., ...

The proximal promoter of the kallikrein-related peptidase 3 gene (KLK3/PSA) contains a single nucleotide polymorphism (G-158A) located within the second canonical half-site for the PSA androgen...

The Tissue Kallikrein Family of Serine Proteases: Functional Roles in Human Disease and Potential as Clinical Biomarkers (2004)

Clements, Judith A., Willemsen, Nicole M., Myers, Stephen A., Dong, Ying

Prostate specific antigen (PSA) or human kallikrein 3 (hK3) has long been an effective biomarker for prostate cancer. Now, other members of the tissue kallikrein (KLK) gene family are fast becoming...

The Tissue Kallikrein Family of Serine Proteases: Functional Roles in Human Disease and Potential as Clinical Biomarkers (2004)

Clements, Judith A., Willemsen, Nicole M., Myers, Steven A., Dong, Ying

Prostate specific antigen (PSA) or human kallikrein 3 (hK3) has long been an effective biomarker for prostate cancer. Now, other members of the tissue kallikrein (KLK) gene family are fast becoming...

The Tissue Kallikrein Family of Serine Proteases: Functional Roles in Human Disease and Potential as Clinical Biomarkers (2004)

Clements, Judith A., Willemsen, Nicole M., Myers, Stephen A., Dong, Ying

Prostate specific antigen (PSA) or human kallikrein 3 (hK3) has long been an effective biomarker for prostate cancer. Now, other members of the tissue kallikrein (KLK) gene family are fast becoming...

The Tissue Kallikrein Family of Serine Proteases: Functional Roles in Human Disease and Potential as Clinical Biomarkers (2004)

Clements, Judith A., Willemsen, Nicole M., Myers, Stephen A., Dong, Ying

Prostate specific antigen (PSA) or human kallikrein 3 (hK3) has long been an effective biomarker for prostate cancer. Now, other members of the tissue kallikrein (KLK) gene family are fast becoming...

The Tissue Kallikrein Family of Serine Proteases: Functional Roles in Human Disease and Potential as Clinical Biomarkers (2004)

Clements, Judith A., Willemsen, Nicole M., Myers, Stephen A., Dong, Ying

Prostate specific antigen (PSA) or human kallikrein 3 (hK3) has long been an effective biomarker for prostate cancer. Now, other members of the tissue kallikrein (KLK) gene family are fast becoming...

The Tissue Kallikrein Family of Serine Proteases: Functional Roles in Human Disease and Potential as Clinical Biomarkers (2004)

Clements, Judith A., Willemsen, Nicole M., Myers, Stephen A., Dong, Ying

Prostate specific antigen (PSA) or human kallikrein 3 (hK3) has long been an effective biomarker for prostate cancer. Now, other members of the tissue kallikrein (KLK) gene family are fast becoming...

The Tissue Kallikrein Family of Serine Proteases: Functional Roles in Human Disease and Potential as Clinical Biomarkers (2004)

Clements, Judith A., Willemsen, Nicole M., Myers, Stephen A., Dong, Ying

Prostate specific antigen (PSA) or human kallikrein 3 (hK3) has long been an effective biomarker for prostate cancer. Now, other members of the tissue kallikrein (KLK) gene family are fast becoming...

The Tissue Kallikrein Family of Serine Proteases: Functional Roles in Human Disease and Potential as Clinical Biomarkers (2004)

Clements, Judith A., Willemsen, Nicole M., Myers, Stephen A., Dong, Ying

Prostate specific antigen (PSA) or human kallikrein 3 (hK3) has long been an effective biomarker for prostate cancer. Now, other members of the tissue kallikrein (KLK) gene family are fast becoming...

The Tissue Kallikrein Family of Serine Proteases: Functional Roles in Human Disease and Potential as Clinical Biomarkers (2004)

Clements, Judith A., Willemsen, Nicole M., Myers, Stephen A., Dong, Ying

Prostate specific antigen (PSA) or human kallikrein 3 (hK3) has long been an effective biomarker for prostate cancer. Now, other members of the tissue kallikrein (KLK) gene family are fast becoming...

Differential Splicing of KLK5 and KLK7 in Epithelial Ovarian Cancer Produces Novel Variants with Potential as Cancer Biomarkers (2003)

Dong, Ying, Kaushal, Aneel, Brattsand, Maria, Nicklin, Jim, Clements, Judith A.

Purpose: The wild-type or variant mRNAs of several kallikrein (KLK) genes, such as KLK4, are highly expressed in ovarian carcinomas and may have potential as tumor markers. Two of these KLK genes...

Differential Splicing of KLK5 and KLK7 in Epithelial Ovarian Cancer Produces Novel Variants with Potential as Cancer Biomarkers (2003)

Dong, Ying, Kaushal, Aneel, Brattsand, Maria, Nicklin, Jim, Clements, Judith A.

Purpose: The wild-type or variant mRNAs of several kallikrein (KLK) genes, such as KLK4, are highly expressed in ovarian carcinomas and may have potential as tumor markers. Two of these KLK genes...

Differential Splicing of KLK5 and KLK7 in Epithelial Ovarian Cancer Produces Novel Variants with Potential as Cancer Biomarkers (2003)

Dong, Ying, Kaushal, Aneel, Brattsand, Maria, Nicklin, Jim, Clements, Judith A.

Purpose: The wild-type or variant mRNAs of several kallikrein (KLK) genes, such as KLK4, are highly expressed in ovarian carcinomas and may have potential as tumor markers. Two of these KLK genes...

Differential Splicing of KLK5 and KLK7 in Epithelial Ovarian Cancer Produces Novel Variants with Potential as Cancer Biomarkers (2003)

Dong, Ying, Kaushal, Aneel, Brattsand, Maria, Nicklin, Jim, Clements, Judith A.

Purpose: The wild-type or variant mRNAs of several kallikrein (KLK) genes, such as KLK4, are highly expressed in ovarian carcinomas and may have potential as tumor markers. Two of these KLK genes...

Differential Splicing of KLK5 and KLK7 in Epithelial Ovarian Cancer Produces Novel Variants with Potential as Cancer Biomarkers (2003)

Dong, Ying, Kaushal, Aneel, Brattsand, Maria, Nicklin, Jim, Clements, Judith A.

Purpose: The wild-type or variant mRNAs of several kallikrein (KLK) genes, such as KLK4, are highly expressed in ovarian carcinomas and may have potential as tumor markers. Two of these KLK genes...

Differential Splicing of KLK5 and KLK7 in Epithelial Ovarian Cancer Produces Novel Variants with Potential as Cancer Biomarkers (2003)

Dong, Ying, Kaushal, Aneel, Brattsand, Maria, Nicklin, Jim, Clements, Judith A.

Purpose: The wild-type or variant mRNAs of several kallikrein (KLK) genes, such as KLK4, are highly expressed in ovarian carcinomas and may have potential as tumor markers. Two of these KLK genes...

Differential Splicing of KLK5 and KLK7 in Epithelial Ovarian Cancer Produces Novel Variants with Potential as Cancer Biomarkers (2003)

Dong, Ying, Kaushal, Aneel, Brattsand, Maria, Nicklin, Jim, Clements, Judith A.

Purpose: The wild-type or variant mRNAs of several kallikrein (KLK) genes, such as KLK4, are highly expressed in ovarian carcinomas and may have potential as tumor markers. Two of these KLK genes...

Differential Splicing of KLK5 and KLK7 in Epithelial Ovarian Cancer Produces Novel Variants with Potential as Cancer Biomarkers (2003)

Dong, Ying, Kaushal, Aneel, Brattsand, Maria, Nicklin, Jim, Clements, Judith A.

Purpose: The wild-type or variant mRNAs of several kallikrein (KLK) genes, such as KLK4, are highly expressed in ovarian carcinomas and may have potential as tumor markers. Two of these KLK genes...

TTYH2, a human homologue of the drosophila melanogaster gene tweety, is located on 17q24 and upregulated in renal cell carcinoma (2001)

Rae, Fiona K., Hooper, John D., Eyre, Helen J., Sutherland, Grant R., Nicol, David L., Clements, Judith A.

Using differential display PCR, we identified a novel gene upregulated in renal cell carcinoma. Characterization of the full-length cDNA and gene revealed that the encoded protein is a human...

TTYH2, a human homologue of the drosophila melanogaster gene tweety, is located on 17q24 and upregulated in renal cell carcinoma (2001)

Rae, Fiona K., Hooper, John D., Eyre, Helen J., Sutherland, Grant R., Nicol, David L., Clements, Judith A.

Using differential display PCR, we identified a novel gene upregulated in renal cell carcinoma. Characterization of the full-length cDNA and gene revealed that the encoded protein is a human...

TTYH2, a human homologue of the drosophila melanogaster gene tweety, is located on 17q24 and upregulated in renal cell carcinoma (2001)

Rae, Fiona K., Hooper, John D., Eyre, Helen J., Sutherland, Grant R., Nicol, David L., Clements, Judith A.

Using differential display PCR, we identified a novel gene upregulated in renal cell carcinoma. Characterization of the full-length cDNA and gene revealed that the encoded protein is a human...

Characterization of a novel gene, STAG1/PMEPA1, upregulated in renal cell carcinoma and other solid tumors (2001)

Rae, Fiona K., Hooper, John D., Nicol, David L., Clements, Judith A.

Using differential display-polymerase chain reaction, we identified a novel gene sequence, designated solid tumor-associated gene 1 (STAG1), that is upregulated in renal cell carcinoma (RCC). The...

Characterization of a novel gene, STAG1/PMEPA1, upregulated in renal cell carcinoma and other solid tumors (2001)

Rae, Fiona K., Hooper, John D., Nicol, David L., Clements, Judith A.

Using differential display-polymerase chain reaction, we identified a novel gene sequence, designated solid tumor-associated gene 1 (STAG1), that is upregulated in renal cell carcinoma (RCC). The...

Characterization of a novel gene, STAG1/PMEPA1, upregulated in renal cell carcinoma and other solid tumors (2001)

Rae, Fiona K., Hooper, John D., Nicol, David L., Clements, Judith A.

Using differential display-polymerase chain reaction, we identified a novel gene sequence, designated solid tumor-associated gene 1 (STAG1), that is upregulated in renal cell carcinoma (RCC). The...

Human Kallikrein 4 (KLK4) Is Highly Expressed in Serous Ovarian Carcinomas (2001)

Dong, Ying, Kaushal, Aneel, Chu, Simon, Bui, Loan T., Fuller, Peter J., Nicklin, Jim, ...

Previous studies indicated that a new member of the human kallikrein (KLK) gene family, KLK4, was expressed in prostate, breast, and endometrial carcinoma cell lines and may have potential as a tumor...

Human Kallikrein 4 (KLK4) Is Highly Expressed in Serous Ovarian Carcinomas (2001)

Dong, Ying, Kaushal, Aneel, Chu, Simon, Bui, Loan T., Fuller, Peter J., Nicklin, Jim, ...

Previous studies indicated that a new member of the human kallikrein (KLK) gene family, KLK4, was expressed in prostate, breast, and endometrial carcinoma cell lines and may have potential as a tumor...

Human Kallikrein 4 (KLK4) Is Highly Expressed in Serous Ovarian Carcinomas (2001)

Dong, Ying, Kaushal, Aneel, Chu, Simon, Bui, Loan T., Fuller, Peter J., Nicklin, Jim, ...

Previous studies indicated that a new member of the human kallikrein (KLK) gene family, KLK4, was expressed in prostate, breast, and endometrial carcinoma cell lines and may have potential as a tumor...

Kallikrein 4 (KLK4), A New Member of the Human Kallikrein Gene Family Is Up-Regulated By Estrogen and Progesterone in the Human Endometrial Cancer Cell Line, KLE (2001)

Myers, Stephen A., Clements, Judith A.

Endometrial cancer is the fourth most common female malignancy in women in developed countries. Estrogen, and to a lesser degree, progesterone, regulate specific target genes that are involved in...

Kallikrein 4 (KLK4), A New Member of the Human Kallikrein Gene Family Is Up-Regulated By Estrogen and Progesterone in the Human Endometrial Cancer Cell Line, KLE (2001)

Myers, Stephen A., Clements, Judith A.

Endometrial cancer is the fourth most common female malignancy in women in developed countries. Estrogen, and to a lesser degree, progesterone, regulate specific target genes that are involved in...

Kallikrein 4 (KLK4), A New Member of the Human Kallikrein Gene Family Is Up-Regulated By Estrogen and Progesterone in the Human Endometrial Cancer Cell Line, KLE (2001)

Myers, Stephen A., Clements, Judith A.

Endometrial cancer is the fourth most common female malignancy in women in developed countries. Estrogen, and to a lesser degree, progesterone, regulate specific target genes that are involved in...

Identification and characterization of KLK14, a novel kallikrein serine protease gene located on human chromosome 19q13.4 and expressed in prostate amd skeletal muscle (2001)

Hooper, John D., Bui, Loan T., Rae, Fiona K., Harvey, Tracey J., Myers, Stephen A., Ashworth, Linda K., ...

The kallikreins are a subfamily of serine proteases encoded in human, mouse, and rat by highly conserved tightly clustered multigene families. Here we report the identification and characterization...

Identification and characterization of KLK14, a novel kallikrein serine protease gene located on human chromosome 19q13.4 and expressed in prostate amd skeletal muscle (2001)

Hooper, John D., Bui, Loan T., Rae, Fiona K., Harvey, Tracey J., Myers, Stephen A., Ashworth, Linda K., ...

The kallikreins are a subfamily of serine proteases encoded in human, mouse, and rat by highly conserved tightly clustered multigene families. Here we report the identification and characterization...

Identification and characterization of KLK14, a novel kallikrein serine protease gene located on human chromosome 19q13.4 and expressed in prostate amd skeletal muscle (2001)

Hooper, John D., Bui, Loan T., Rae, Fiona K., Harvey, Tracey J., Myers, Stephen A., Ashworth, Linda K., ...

The kallikreins are a subfamily of serine proteases encoded in human, mouse, and rat by highly conserved tightly clustered multigene families. Here we report the identification and characterization...

Type II transmembrane serine proteases: Insights into an emerging class of cell surface proteolytic enzymes (2001)

Hooper, John D., Clements, Judith A., Quigley, James P., Antalis, Toni M.

Cell surface proteolysis has emerged as an important mechanism for the generation of biologically active proteins that mediate a diverse range of cellular functions. The proteolytic activities of...

Type II transmembrane serine proteases: Insights into an emerging class of cell surface proteolytic enzymes (2001)

Hooper, John D., Clements, Judith A., Quigley, James P., Antalis, Tony M.

Cell surface proteolysis has emerged as an important mechanism for the generation of biologically active proteins that mediate a diverse range of cellular functions. The proteolytic activities of...

Type II transmembrane serine proteases: Insights into an emerging class of cell surface proteolytic enzymes (2001)

Hooper, John D., Clements, Judith A., Quigley, James P., Antalis, Toni M.

Cell surface proteolysis has emerged as an important mechanism for the generation of biologically active proteins that mediate a diverse range of cellular functions. The proteolytic activities of...

TTYH2, a human homologue of the drosophila melanogaster gene tweety, is located on 17q24 and upregulated in renal cell carcinoma (2001)

Rae, Fiona K., Hooper, John D., Eyre, Helen J., Sutherland, Grant R., Nicol, David L., Clements, Judith A.

Using differential display PCR, we identified a novel gene upregulated in renal cell carcinoma. Characterization of the full-length cDNA and gene revealed that the encoded protein is a human...

Characterization of a novel gene, STAG1/PMEPA1, upregulated in renal cell carcinoma and other solid tumors (2001)

Rae, Fiona K., Hooper, John D., Nicol, David L., Clements, Judith A.

Using differential display-polymerase chain reaction, we identified a novel gene sequence, designated solid tumor-associated gene 1 (STAG1), that is upregulated in renal cell carcinoma (RCC). The...

Identification and characterization of KLK14, a novel kallikrein serine protease gene located on human chromosome 19q13.4 and expressed in prostate amd skeletal muscle (2001)

Hooper, John D., Bui, Loan T., Rae, Fiona K., Harvey, Tracey J., Myers, Stephen A., Ashworth, Linda K., ...

The kallikreins are a subfamily of serine proteases encoded in human, mouse, and rat by highly conserved tightly clustered multigene families. Here we report the identification and characterization...

Kallikrein 4 (KLK4), A New Member of the Human Kallikrein Gene Family Is Up-Regulated By Estrogen and Progesterone in the Human Endometrial Cancer Cell Line, KLE (2001)

Myers, Stephen A., Clements, Judith A.

Endometrial cancer is the fourth most common female malignancy in women in developed countries. Estrogen, and to a lesser degree, progesterone, regulate specific target genes that are involved in...

Human Kallikrein 4 (KLK4) Is Highly Expressed in Serous Ovarian Carcinomas (2001)

Dong, Ying, Kaushal, Aneel, Chu, Simon, Bui, Loan T., Fuller, Peter J., Nicklin, Jim, ...

Previous studies indicated that a new member of the human kallikrein (KLK) gene family, KLK4, was expressed in prostate, breast, and endometrial carcinoma cell lines and may have potential as a tumor...

Type II transmembrane serine proteases: Insights into an emerging class of cell surface proteolytic enzymes (2001)

Hooper, John D., Clements, Judith A., Quigley, James P., Antalis, Toni M.

Cell surface proteolysis has emerged as an important mechanism for the generation of biologically active proteins that mediate a diverse range of cellular functions. The proteolytic activities of...

Type II transmembrane serine proteases: Insights into an emerging class of cell surface proteolytic enzymes (2001)

Hooper, John D., Clements, Judith A., Quigley, James P., Antalis, Toni M.

Cell surface proteolysis has emerged as an important mechanism for the generation of biologically active proteins that mediate a diverse range of cellular functions. The proteolytic activities of...

TTYH2, a human homologue of the drosophila melanogaster gene tweety, is located on 17q24 and upregulated in renal cell carcinoma (2001)

Rae, Fiona K., Hooper, John D., Eyre, Helen J., Sutherland, Grant R., Nicol, David L., Clements, Judith A.

Using differential display PCR, we identified a novel gene upregulated in renal cell carcinoma. Characterization of the full-length cDNA and gene revealed that the encoded protein is a human...

Characterization of a novel gene, STAG1/PMEPA1, upregulated in renal cell carcinoma and other solid tumors (2001)

Rae, Fiona K., Hooper, John D., Nicol, David L., Clements, Judith A.

Using differential display-polymerase chain reaction, we identified a novel gene sequence, designated solid tumor-associated gene 1 (STAG1), that is upregulated in renal cell carcinoma (RCC). The...

Identification and characterization of KLK14, a novel kallikrein serine protease gene located on human chromosome 19q13.4 and expressed in prostate amd skeletal muscle (2001)

Hooper, John D., Bui, Loan T., Rae, Fiona K., Harvey, Tracey J., Myers, Stephen A., Ashworth, Linda K., ...

The kallikreins are a subfamily of serine proteases encoded in human, mouse, and rat by highly conserved tightly clustered multigene families. Here we report the identification and characterization...

Kallikrein 4 (KLK4), A New Member of the Human Kallikrein Gene Family Is Up-Regulated By Estrogen and Progesterone in the Human Endometrial Cancer Cell Line, KLE (2001)

Myers, Stephen A., Clements, Judith A.

Endometrial cancer is the fourth most common female malignancy in women in developed countries. Estrogen, and to a lesser degree, progesterone, regulate specific target genes that are involved in...

Human Kallikrein 4 (KLK4) Is Highly Expressed in Serous Ovarian Carcinomas (2001)

Dong, Ying, Kaushal, Aneel, Chu, Simon, Bui, Loan T., Fuller, Peter J., Nicklin, Jim, ...

Previous studies indicated that a new member of the human kallikrein (KLK) gene family, KLK4, was expressed in prostate, breast, and endometrial carcinoma cell lines and may have potential as a tumor...

Type II transmembrane serine proteases: Insights into an emerging class of cell surface proteolytic enzymes (2001)

Hooper, John D., Clements, Judith A., Quigley, James P., Antalis, Toni M.

Cell surface proteolysis has emerged as an important mechanism for the generation of biologically active proteins that mediate a diverse range of cellular functions. The proteolytic activities of...

TTYH2, a human homologue of the drosophila melanogaster gene tweety, is located on 17q24 and upregulated in renal cell carcinoma (2001)

Rae, Fiona K., Hooper, John D., Eyre, Helen J., Sutherland, Grant R., Nicol, David L., Clements, Judith A.

Using differential display PCR, we identified a novel gene upregulated in renal cell carcinoma. Characterization of the full-length cDNA and gene revealed that the encoded protein is a human...

Characterization of a novel gene, STAG1/PMEPA1, upregulated in renal cell carcinoma and other solid tumors (2001)

Rae, Fiona K., Hooper, John D., Nicol, David L., Clements, Judith A.

Using differential display-polymerase chain reaction, we identified a novel gene sequence, designated solid tumor-associated gene 1 (STAG1), that is upregulated in renal cell carcinoma (RCC). The...

Identification and characterization of KLK14, a novel kallikrein serine protease gene located on human chromosome 19q13.4 and expressed in prostate amd skeletal muscle (2001)

Hooper, John D., Bui, Loan T., Rae, Fiona K., Harvey, Tracey J., Myers, Stephen A., Ashworth, Linda K., ...

The kallikreins are a subfamily of serine proteases encoded in human, mouse, and rat by highly conserved tightly clustered multigene families. Here we report the identification and characterization...

Kallikrein 4 (KLK4), A New Member of the Human Kallikrein Gene Family Is Up-Regulated By Estrogen and Progesterone in the Human Endometrial Cancer Cell Line, KLE (2001)

Myers, Stephen A., Clements, Judith A.

Endometrial cancer is the fourth most common female malignancy in women in developed countries. Estrogen, and to a lesser degree, progesterone, regulate specific target genes that are involved in...

Human Kallikrein 4 (KLK4) Is Highly Expressed in Serous Ovarian Carcinomas (2001)

Dong, Ying, Kaushal, Aneel, Chu, Simon, Bui, Loan T., Fuller, Peter J., Nicklin, Jim, ...

Previous studies indicated that a new member of the human kallikrein (KLK) gene family, KLK4, was expressed in prostate, breast, and endometrial carcinoma cell lines and may have potential as a tumor...

Type II transmembrane serine proteases: Insights into an emerging class of cell surface proteolytic enzymes (2001)

Hooper, John D., Clements, Judith A., Quigley, James P., Antalis, Toni M.

Cell surface proteolysis has emerged as an important mechanism for the generation of biologically active proteins that mediate a diverse range of cellular functions. The proteolytic activities of...

TTYH2, a human homologue of the drosophila melanogaster gene tweety, is located on 17q24 and upregulated in renal cell carcinoma (2001)

Rae, Fiona K., Hooper, John D., Eyre, Helen J., Sutherland, Grant R., Nicol, David L., Clements, Judith A.

Using differential display PCR, we identified a novel gene upregulated in renal cell carcinoma. Characterization of the full-length cDNA and gene revealed that the encoded protein is a human...

Characterization of a novel gene, STAG1/PMEPA1, upregulated in renal cell carcinoma and other solid tumors (2001)

Rae, Fiona K., Hooper, John D., Nicol, David L., Clements, Judith A.

Using differential display-polymerase chain reaction, we identified a novel gene sequence, designated solid tumor-associated gene 1 (STAG1), that is upregulated in renal cell carcinoma (RCC). The...

Identification and characterization of KLK14, a novel kallikrein serine protease gene located on human chromosome 19q13.4 and expressed in prostate amd skeletal muscle (2001)

Hooper, John D., Bui, Loan T., Rae, Fiona K., Harvey, Tracey J., Myers, Stephen A., Ashworth, Linda K., ...

The kallikreins are a subfamily of serine proteases encoded in human, mouse, and rat by highly conserved tightly clustered multigene families. Here we report the identification and characterization...

Kallikrein 4 (KLK4), A New Member of the Human Kallikrein Gene Family Is Up-Regulated By Estrogen and Progesterone in the Human Endometrial Cancer Cell Line, KLE (2001)

Myers, Stephen A., Clements, Judith A.

Endometrial cancer is the fourth most common female malignancy in women in developed countries. Estrogen, and to a lesser degree, progesterone, regulate specific target genes that are involved in...

Human Kallikrein 4 (KLK4) Is Highly Expressed in Serous Ovarian Carcinomas (2001)

Dong, Ying, Kaushal, Aneel, Chu, Simon, Bui, Loan T., Fuller, Peter J., Nicklin, Jim, ...

Previous studies indicated that a new member of the human kallikrein (KLK) gene family, KLK4, was expressed in prostate, breast, and endometrial carcinoma cell lines and may have potential as a tumor...

Type II transmembrane serine proteases: Insights into an emerging class of cell surface proteolytic enzymes (2001)

Hooper, John D., Clements, Judith A., Quigley, James P., Antalis, Toni M.

Cell surface proteolysis has emerged as an important mechanism for the generation of biologically active proteins that mediate a diverse range of cellular functions. The proteolytic activities of...

TTYH2, a human homologue of the drosophila melanogaster gene tweety, is located on 17q24 and upregulated in renal cell carcinoma (2001)

Rae, Fiona K., Hooper, John D., Eyre, Helen J., Sutherland, Grant R., Nicol, David L., Clements, Judith A.

Using differential display PCR, we identified a novel gene upregulated in renal cell carcinoma. Characterization of the full-length cDNA and gene revealed that the encoded protein is a human...

Characterization of a novel gene, STAG1/PMEPA1, upregulated in renal cell carcinoma and other solid tumors (2001)

Rae, Fiona K., Hooper, John D., Nicol, David L., Clements, Judith A.

Using differential display-polymerase chain reaction, we identified a novel gene sequence, designated solid tumor-associated gene 1 (STAG1), that is upregulated in renal cell carcinoma (RCC). The...

Identification and characterization of KLK14, a novel kallikrein serine protease gene located on human chromosome 19q13.4 and expressed in prostate amd skeletal muscle (2001)

Hooper, John D., Bui, Loan T., Rae, Fiona K., Harvey, Tracey J., Myers, Stephen A., Ashworth, Linda K., ...

The kallikreins are a subfamily of serine proteases encoded in human, mouse, and rat by highly conserved tightly clustered multigene families. Here we report the identification and characterization...

Kallikrein 4 (KLK4), A New Member of the Human Kallikrein Gene Family Is Up-Regulated By Estrogen and Progesterone in the Human Endometrial Cancer Cell Line, KLE (2001)

Myers, Stephen A., Clements, Judith A.

Endometrial cancer is the fourth most common female malignancy in women in developed countries. Estrogen, and to a lesser degree, progesterone, regulate specific target genes that are involved in...

Human Kallikrein 4 (KLK4) Is Highly Expressed in Serous Ovarian Carcinomas (2001)

Dong, Ying, Kaushal, Aneel, Chu, Simon, Bui, Loan T., Fuller, Peter J., Nicklin, Jim, ...

Previous studies indicated that a new member of the human kallikrein (KLK) gene family, KLK4, was expressed in prostate, breast, and endometrial carcinoma cell lines and may have potential as a tumor...

Type II transmembrane serine proteases: Insights into an emerging class of cell surface proteolytic enzymes (2001)

Hooper, John D., Clements, Judith A., Quigley, James P., Antalis, Toni M.

Cell surface proteolysis has emerged as an important mechanism for the generation of biologically active proteins that mediate a diverse range of cellular functions. The proteolytic activities of...

TTYH2, a human homologue of the drosophila melanogaster gene tweety, is located on 17q24 and upregulated in renal cell carcinoma (2001)

Rae, Fiona K., Hooper, John D., Eyre, Helen J., Sutherland, Grant R., Nicol, David L., Clements, Judith A.

Using differential display PCR, we identified a novel gene upregulated in renal cell carcinoma. Characterization of the full-length cDNA and gene revealed that the encoded protein is a human...

Characterization of a novel gene, STAG1/PMEPA1, upregulated in renal cell carcinoma and other solid tumors (2001)

Rae, Fiona K., Hooper, John D., Nicol, David L., Clements, Judith A.

Using differential display-polymerase chain reaction, we identified a novel gene sequence, designated solid tumor-associated gene 1 (STAG1), that is upregulated in renal cell carcinoma (RCC). The...

Identification and characterization of KLK14, a novel kallikrein serine protease gene located on human chromosome 19q13.4 and expressed in prostate amd skeletal muscle (2001)

Hooper, John D., Bui, Loan T., Rae, Fiona K., Harvey, Tracey J., Myers, Stephen A., Ashworth, Linda K., ...

The kallikreins are a subfamily of serine proteases encoded in human, mouse, and rat by highly conserved tightly clustered multigene families. Here we report the identification and characterization...

Kallikrein 4 (KLK4), A New Member of the Human Kallikrein Gene Family Is Up-Regulated By Estrogen and Progesterone in the Human Endometrial Cancer Cell Line, KLE (2001)

Myers, Stephen A., Clements, Judith A.

Endometrial cancer is the fourth most common female malignancy in women in developed countries. Estrogen, and to a lesser degree, progesterone, regulate specific target genes that are involved in...

Human Kallikrein 4 (KLK4) Is Highly Expressed in Serous Ovarian Carcinomas (2001)

Dong, Ying, Kaushal, Aneel, Chu, Simon, Bui, Loan T., Fuller, Peter J., Nicklin, Jim, ...

Previous studies indicated that a new member of the human kallikrein (KLK) gene family, KLK4, was expressed in prostate, breast, and endometrial carcinoma cell lines and may have potential as a tumor...

Tissue-specific expression patterns and fine mapping of the human Kallikrein (KLK) locus on proximal 19q13.4 (2000)

Harvey, Tracey J., Hooper, John D., Myers, Stephen A., Stephenson, Sally-Anne, Ashworth, Linda K., Clements, Judith A.

The tissue or glandular kallikreins (KLK) are members of a highly conserved multigene family encoding serine proteases that are central to many biological processes. The rodent KLK families are...

Tissue-specific expression patterns and fine mapping of the human Kallikrein (KLK) locus on proximal 19q13.4 (2000)

Harvey, Tracey J., Hooper, John D., Myers, Stephen A., Stephenson, Sally-Anne, Ashworth, Linda K., Clements, Judith A.

The tissue or glandular kallikreins (KLK) are membersof a highly conserved multigene family encodingserine proteases that are central to many biological processes.The rodent KLK families are large,...

Tissue-specific expression patterns and fine mapping of the human Kallikrein (KLK) locus on proximal 19q13.4 (2000)

Harvey, Tracey J., Hooper, John D., Myers, Stephen A., Stephenson, Sally-Anne, Ashworth, Linda K., Clements, Judith A.

The tissue or glandular kallikreins (KLK) are members of a highly conserved multigene family encoding serine proteases that are central to many biological processes. The rodent KLK families are...

Tissue-specific expression patterns and fine mapping of the human Kallikrein (KLK) locus on proximal 19q13.4 (2000)

Harvey, Tracey J., Hooper, John D., Myers, Stephen A., Stephenson, Sally-Anne, Ashworth, Linda K., Clements, Judith A.

The tissue or glandular kallikreins (KLK) are members of a highly conserved multigene family encoding serine proteases that are central to many biological processes. The rodent KLK families are...

Tissue-specific expression patterns and fine mapping of the human Kallikrein (KLK) locus on proximal 19q13.4 (2000)

Harvey, Tracey J., Hooper, John D., Myers, Stephen A., Stephenson, Sally-Anne, Ashworth, Linda K., Clements, Judith A.

The tissue or glandular kallikreins (KLK) are members of a highly conserved multigene family encoding serine proteases that are central to many biological processes. The rodent KLK families are...

Tissue-specific expression patterns and fine mapping of the human Kallikrein (KLK) locus on proximal 19q13.4 (2000)

Harvey, Tracey J., Hooper, John D., Myers, Stephen A., Stephenson, Sally-Anne, Ashworth, Linda K., Clements, Judith A.

The tissue or glandular kallikreins (KLK) are members of a highly conserved multigene family encoding serine proteases that are central to many biological processes. The rodent KLK families are...

Tissue-specific expression patterns and fine mapping of the human Kallikrein (KLK) locus on proximal 19q13.4 (2000)

Harvey, Tracey J., Hooper, John D., Myers, Stephen A., Stephenson, Sally-Anne, Ashworth, Linda K., Clements, Judith A.

The tissue or glandular kallikreins (KLK) are members of a highly conserved multigene family encoding serine proteases that are central to many biological processes. The rodent KLK families are...

Tissue-specific expression patterns and fine mapping of the human Kallikrein (KLK) locus on proximal 19q13.4 (2000)

Harvey, Tracey J., Hooper, John D., Myers, Stephen A., Stephenson, Sally-Anne, Ashworth, Linda K., Clements, Judith A.

The tissue or glandular kallikreins (KLK) are members of a highly conserved multigene family encoding serine proteases that are central to many biological processes. The rodent KLK families are...

Tissue-specific expression patterns and fine mapping of the human Kallikrein (KLK) locus on proximal 19q13.4 (2000)

Harvey, Tracey J., Hooper, John D., Myers, Stephen A., Stephenson, Sally-Anne, Ashworth, Linda K., Clements, Judith A.

The tissue or glandular kallikreins (KLK) are members of a highly conserved multigene family encoding serine proteases that are central to many biological processes. The rodent KLK families are...