Child Psychiatry Branch, and (2009)
Nitin Gogtay, Anna Ordonez, David H. Herman, Kiralee M. Hayashi, Cathy Vaituzis, Marge Lenane, ...
doi:10.1111/j.1469-7610.2007.01747.x Dynamic mapping of cortical development before and after the onset of pediatric bipolar illness
Philip Shaw, Ph. D, Deanna K. Greenstein, ...
Attention deficit hyperactivity disorder (ADHD) is a developmental disorder affecting 5%–10 % of school-age children and 4.4 % of adults (1). Clinical features include inattentiveness, motor...
Keith J. Worsley, Steve Robbins, Tomas Paus, Jonathan Taylor, Jay N. Giedd, Judith L. Rapoport, ...
We present a unified statistical approach to deformation-based morphometry applied to the cortical surface. The cerebral cortex has the topology of a 2D highly convoluted sheet. As the brain develops...
Mapping cortical change in Alzheimer's disease, brain development, and schizophrenia (2004)
Thompson, Paul M., Hayashi, Kiralee M., Sowell, Elizabeth R., Gogtay, Nitin, Giedd, Jay N., Rapoport, Judith L., ...
This paper describes algorithms that can identify patterns of brain structure and function associated with Alzheimer's disease, schizophrenia, normal aging, and abnormal brain development based on...
Mapping cortical change in Alzheimer's disease, brain development, and schizophrenia (2004)
Thompson, Paul M., Hayashi, Kiralee M., Sowell, Elizabeth R., Gogtay, Nitin, Giedd, Jay N., Rapoport, Judith L., ...
This paper describes algorithms that can identify patterns of brain structure and function associated with Alzheimer's disease, schizophrenia, normal aging, and abnormal brain development based on...
Structural Mri Data, Paul Thompson Phd, Stephen Lawrie, ...
UCLA School of Medicine Introduction Recent advances in medical imaging have revolutionized our ability to investigate disease. Current brain mapping initiatives are charting brain structure and...
Judith L. Rapoport, Md Jay, N. Giedd, Md Jonathan Blumenthal, Ma Susan Hamburger, Alex Zijdenbos, ...
Background: Adolescence provides a window to examine regional and disease-specific late abnormal brain development in schizophrenia. Because previous data showed progressive brain ventricular...
Quantitative Magnetic Resonance Imaging of Human Brain Development: Ages 4-18 (1996)
Giedd, Jay N., Snell, John W., Lange, Nicholas, Rajapakse, Jagath C., Casey, B. J., Kozuch, Patricia L., ...
Brain magnetic resonance images (MRI) of 104 healthy children and adolescents, aged 4–18, showed significant effects of age and gender on brain morphometry. Males had larger cerebral (9%)...
Childhood-Onset Schizophrenia: An NIMH Study in Progress (1994)
Gordon, Charles T., Frazier, Jean A., McKenna, Kathleen, Giedd, Jay, Zametkin, Alan, Kaysen, Debra, ...
An ongoing study of the phenomenology, genetics, neuropsychology, physiology (eye tracking, autonomic responsivity), neuroimaging, biochemistry, and pharmacology of childhood-onset schizophrenia is...
Burg, Cheryl, Quinn, Patricia O., Rapoport, Judith L.
One hundred and twenty-three infants selected from a normal newborn screening of 933 on the basis of minor physical anomalies of face, head, hands, and feet were evaluated at one year of age. At that...
Thompson, Paul M., Vidal, Christine, Giedd, Jay N., Gochman, Peter, Blumenthal, Jonathan, Nicolson, Robert, ...
Neurodevelopmental models for the pathology of schizophrenia propose both polygenetic and environmental risks, as well as early (pre/perinatal) and late (usually adolescent) developmental brain...
Liu, Hui, Heath, Simon C., Sobin, Christina, Roos, J. Louw, Galke, Brandi L., Blundell, Maude L., ...
The location of a schizophrenia susceptibility locus at chromosome 22q11 has been suggested by genome-wide linkage studies. Additional support was provided by the observation of a...
Genetic variation in the 22q11 locus and susceptibility to schizophrenia
Liu, Hui, Abecasis, Gonçalo R., Heath, Simon C., Knowles, Alyson, Demars, Sandra, Chen, Ying-Jiun, ...
An increased prevalence of microdeletions at the 22q11 locus has been reported in samples of patients with schizophrenia. 22q11 microdeletions represent the highest known genetic risk factor for the...
Dynamic mapping of human cortical development during childhood through early adulthood
Gogtay, Nitin, Giedd, Jay N., Lusk, Leslie, Hayashi, Kiralee M., Greenstein, Deanna, Vaituzis, A. Catherine, ...
We report the dynamic anatomical sequence of human cortical gray matter development between the age of 4–21 years using quantitative four-dimensional maps and time-lapse sequences. Thirteen healthy...
Thompson, Paul M., Vidal, Christine, Giedd, Jay N., Gochman, Peter, Blumenthal, Jonathan, Nicolson, Robert, ...
Neurodevelopmental models for the pathology of schizophrenia propose both polygenetic and environmental risks, as well as early (pre/perinatal) and late (usually adolescent) developmental brain...
Liu, Hui, Heath, Simon C., Sobin, Christina, Roos, J. Louw, Galke, Brandi L., Blundell, Maude L., ...
The location of a schizophrenia susceptibility locus at chromosome 22q11 has been suggested by genome-wide linkage studies. Additional support was provided by the observation of a...
Genetic variation in the 22q11 locus and susceptibility to schizophrenia
Liu, Hui, Abecasis, Gonçalo R., Heath, Simon C., Knowles, Alyson, Demars, Sandra, Chen, Ying-Jiun, ...
An increased prevalence of microdeletions at the 22q11 locus has been reported in samples of patients with schizophrenia. 22q11 microdeletions represent the highest known genetic risk factor for the...
Dynamic mapping of human cortical development during childhood through early adulthood
Gogtay, Nitin, Giedd, Jay N., Lusk, Leslie, Hayashi, Kiralee M., Greenstein, Deanna, Vaituzis, A. Catherine, ...
We report the dynamic anatomical sequence of human cortical gray matter development between the age of 4–21 years using quantitative four-dimensional maps and time-lapse sequences. Thirteen healthy...
Arcos-Burgos, Mauricio, Castellanos, F. Xavier, Pineda, David, Lopera, Francisco, David Palacio, Juan, Guillermo Palacio, Luis, ...
Attention-deficit/hyperactivity disorder (ADHD [MIM 143465]) is the most common behavioral disorder of childhood. Twin, adoption, segregation, association, and linkage studies have confirmed that...
Gogtay, Nitin, Lu, Allen, Leow, Alex D., Klunder, Andrea D., Lee, Agatha D., Chavez, Alex, ...
Earlier studies revealed progressive cortical gray matter (GM) loss in childhood-onset schizophrenia (COS) across both lateral and medial surfaces of the developing brain. Here, we use tensor-based...