Jukka Westermarck

CIP2A Is Associated with Human Breast Cancer Aggressivity (2009)

Côme, Christophe, Laine, Anni, Chanrion, Maïa, Edgren, Henrik, Mattila, Elina, Lin, Xiaoling, ...

Clinical Cancer Research Vol.15 Nr.16, 5092 - 5100

MYC-Dependent Regulation and Prognostic Role of CIP2A in Gastric Cancer (2009)

Khanna, Anchit, Böckelman, Camilla, Hemmes, Annabrita, Junttila, Melissa R., Wiksten, Jan-Patrik, Lundin, Mikael, ...

Background Cancerous inhibitor of protein phosphatase 2A (CIP2A) is a recently identified human oncoprotein that stabilizes the c-Myc (MYC) protein. However, the clinical relevance of CIP2A to human...

C-jun supports ribosomal RNA processing and nucleolar localization of RNA helicase DDX21 (2008)

Holmström, Tim H., Mialon, Antoine, Kallio, Marko, Nymalm, Yvonne, Mannermaa, Leni, Holm, Tina, ...

Journal of Biological Chemistry Vol.283 Nr.11, 7046 - 7053

Identification of nucleolar effects in JNK-deficient cells (2008)

Mialon, Antoine, Thastrup, Jacob, Kallunki, Tuula, Mannermaa, Leni, Westermarck, Jukka, Holmström, Tim H.

FEBS Letters Vol.582 Nr.20, 3145 - 3151

Transcriptional regulation of fibroblast collagenase (MMP-1) gene expression / (1997)

Westermarck, Jukka.

Diss. -- Turun yliopisto.

p38 Mitogen-Activated Protein Kinase-Dependent Activation of Protein Phosphatases 1 and 2A Inhibits MEK1 and MEK2 Activity and Collagenase 1 (MMP-1) Gene Expression

Westermarck, Jukka, Li, Song-Ping, Kallunki, Tuula, Han, Jiahuai, Kähäri, Veli-Matti

Degradation of collagenous extracellular matrix by collagenase 1 (also known as matrix metalloproteinase 1 [MMP-1]) plays a role in the pathogenesis of various destructive disorders, such as...

The DEXD/H-box RNA helicase RHII/Gu is a co-factor for c-Jun-activated transcription

Westermarck, Jukka, Weiss, Carsten, Saffrich, Rainer, Kast, Jürgen, Musti, Anna-Maria, Wessely, Matthias, ...

Tandem affinity purification (TAP) and mass spectrometric peptide sequencing showed that the DEAD-box RNA helicase RHII/Gu is a functional interaction partner of c-Jun in human cells. The N-terminal...

DNA Topoisomerase I Is a Cofactor for c-Jun in the Regulation of Epidermal Growth Factor Receptor Expression and Cancer Cell Proliferation

Mialon, Antoine, Sankinen, Matti, Söderström, Henrik, Junttila, Teemu T., Holmström, Tim, Koivusalo, Riku, ...

DNA topoisomerase I (Topo I) is a molecular target for the anticancer agent topotecan in the treatment of small cell lung cancer and ovarian carcinomas. However, the molecular mechanisms by which...

p38 Mitogen-Activated Protein Kinase-Dependent Activation of Protein Phosphatases 1 and 2A Inhibits MEK1 and MEK2 Activity and Collagenase 1 (MMP-1) Gene Expression

Westermarck, Jukka, Li, Song-Ping, Kallunki, Tuula, Han, Jiahuai, Kähäri, Veli-Matti

Degradation of collagenous extracellular matrix by collagenase 1 (also known as matrix metalloproteinase 1 [MMP-1]) plays a role in the pathogenesis of various destructive disorders, such as...

The DEXD/H-box RNA helicase RHII/Gu is a co-factor for c-Jun-activated transcription

Westermarck, Jukka, Weiss, Carsten, Saffrich, Rainer, Kast, Jürgen, Musti, Anna-Maria, Wessely, Matthias, ...

Tandem affinity purification (TAP) and mass spectrometric peptide sequencing showed that the DEAD-box RNA helicase RHII/Gu is a functional interaction partner of c-Jun in human cells. The N-terminal...

DNA Topoisomerase I Is a Cofactor for c-Jun in the Regulation of Epidermal Growth Factor Receptor Expression and Cancer Cell Proliferation

Mialon, Antoine, Sankinen, Matti, Söderström, Henrik, Junttila, Teemu T., Holmström, Tim, Koivusalo, Riku, ...

DNA topoisomerase I (Topo I) is a molecular target for the anticancer agent topotecan in the treatment of small cell lung cancer and ovarian carcinomas. However, the molecular mechanisms by which...

Integrin α2β1 Mediates Isoform-Specific Activation of p38 and Upregulation of Collagen Gene Transcription by a Mechanism Involving the α2 Cytoplasmic Tail

Ivaska, Johanna, Reunanen, Hilkka, Westermarck, Jukka, Koivisto, Leeni, Kähäri, Veli-Matti, Heino, Jyrki

Two collagen receptors, integrins α1β1 and α2β1, can regulate distinct functions in cells. Ligation of α1β1, unlike α2β1, has been shown to result in recruitment of Shc and activation of the...