Crossman, Lisa C, Gould, Virginia C, Dow, J Maxwell, Vernikos, Georgios S, Okazaki, Aki, Sebaihia, Mohammed, ...
Abstract Background Stenotrophomonas maltophilia is a nosocomial opportunistic pathogen of the Xanthomonadaceae. The organism has been isolated from both clinical and soil environments in addition to...
Walker, Thomas, Klasson, Lisa, Sebaihia, Mohammed, Sanders, Mandy J, Thomson, Nicholas R, Parkhill, Julian, ...
Abstract Background Wolbachia are obligate endosymbiotic bacteria maternally transmitted through the egg cytoplasm that are responsible for several reproductive disorders in their insect hosts, such...
Re-annotation and re-analysis of the Campylobacter jejuniNCTC11168 genome sequence (2007)
Gundogdu, Ozan, Bentley, Stephen D, Holden, Matt T, Parkhill, Julian, Dorrell, Nick, Wren, Brendan W
Abstract Background Campylobacter jejuni is the leading bacterial cause of human gastroenteritis in the developed world. To improve our understanding of this important human pathogen, the C. jejuni...
Genetic flux over time in the Salmonellalineage (2007)
Vernikos, Georgios S, Thomson, Nicholas R, Parkhill, Julian
Abstract Background DNA sequences that are shared between closely related organisms while being absent from their common ancestor and from sister lineages of that ancestor are likely to have been...
Bentley, Stephen D., Vernikos, George S., Snyder, Lori A. S., Churcher, Carol, Arrowsmith, Claire, Chillingworth, Tracey, ...
The bacterium Neisseria meningitidis is commonly found harmlessly colonising the mucosal surfaces of the human nasopharynx. Occasionally strains can invade host tissues causing septicaemia and...
The genome of Rhizobium leguminosarumhas recognizable core and accessory components (2006)
Young, J Peter W, Crossman, Lisa C, Johnston, Andrew WB, Thomson, Nicholas R, Ghazoui, Zara F, Hull, Katherine H, ...
Abstract Background Rhizobium leguminosarum is an α-proteobacterial N 2 -fixing symbiont of legumes that has been the subject of more than a thousand publications. Genes for the symbiotic...
Microevolution and history of the plague bacillus, Yersinia pestis (2004)
Achtman,Mark, Morelli,Giovanna, Zhu,Peixuan X., Wirth,Thierry, Diehl,Ines, Kusecek,Barica, ...
The association of historical plague pandemics with Yersinia pestis remains controversial, partly because the evolutionary history of this largely monomorphic bacterium was unknown. The...
Microevolution and history of the plague bacillus, Yersinia pestis (2004)
Achtman, Mark, Morelli, Giovanna, Zhu, Peixuan X., Wirth, Thierry, Diehl, Ines, Kusecek, Barica, ...
Genomic plasticity of the causative agent of melioidosis, Burkholderia pseudomallei (2004)
Holden, Matthew T. G., Titball, Richard W., Peacock, Sharon J., Cerdeno-Tarraga, Ana M., Atkins, Timothy, Crossman, Lisa C., ...
Yes
Genomic plasticity of the causative agent of melioidosis, Burkholderia pseudomallei (2004)
Holden, Matthew T. G., Titball, Richard W., Peacock, Sharon J., Cerdeno-Tarraga, Ana M., Atkins, Timothy, Crossman, Lisa C., ...
Yes
Genomic plasticity of the causative agent of melioidosis, Burkholderia pseudomallei (2004)
Holden, Matthew T. G., Titball, Richard W., Peacock, Sharon J., Cerdeno-Tarraga, Ana M., Atkins, Timothy, Crossman, Lisa C., ...
Parkhill,Julian, Sebaihia,Mohammed, Preston,Andrew, Murphy,Lee D., Thomson,Nicholas, Harris,David E., ...
Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica are closely related Gram-negative -proteobacteria that colonize the respiratory tracts of mammals. B. pertussis is a...
Parkhill, Julian, Sebaihia, Mohammed, Preston, Andrew, Murphy, Lee D., Thomson, Nicholas, Harris, David E., ...
Prentice, Michael B., James, Keith D., Parkhill, Julian, Baker, Stephen G., Stevens, Kim, Simmonds, Mark N., ...
Population genetic studies suggest that Yersinia pestis, the cause of plague, is a clonal pathogen that has recently emerged from Yersinia pseudotuberculosis. Plasmid acquisition is likely to have...
Genetic Basis for Lipopolysaccharide O-Antigen Biosynthesis in Bordetellae
Preston, Andrew, Allen, Andrew G., Cadisch, Joanna, Thomas, Richard, Stevens, Kim, Churcher, Carol M., ...
Bordetella bronchiseptica and Bordetella parapertussis express a surface polysaccharide, attached to a lipopolysaccharide, which has been called O antigen. This structure is absent from Bordetella...
Salmonella enterica Serovar Typhi Possesses a Unique Repertoire of Fimbrial Gene Sequences
Townsend, Stacy M., Kramer, Naomi E., Edwards, Robert, Baker, Stephen, Hamlin, Nancy, Simmonds, Mark, ...
Salmonella enterica serotype Typhi differs from nontyphoidal Salmonella serotypes by its strict host adaptation to humans and higher primates. Since fimbriae have been implicated in host adaptation,...
McClelland, Michael, Florea, Liliana, Sanderson, Ken, Clifton, Sandra W., Parkhill, Julian, Churcher, Carol, ...
The Escherichia coli K-12 genome (ECO) was compared with the sampled genomes of the sibling species Salmonella enterica serovars Typhimurium, Typhi and Paratyphi A (collectively referred to as SAL)...
Berry, Colin, O'Neil, Susan, Ben-Dov, Eitan, Jones, Andrew F., Murphy, Lee, Quail, Michael A., ...
The entire 127,923-bp sequence of the toxin-encoding plasmid pBtoxis from Bacillus thuringiensis subsp. israelensis is presented and analyzed. In addition to the four known Cry and two known Cyt...
The complete genome sequence of Mycobacterium bovis
Garnier, Thierry, Eiglmeier, Karin, Camus, Jean-Christophe, Medina, Nadine, Mansoor, Huma, Pryor, Melinda, ...
Mycobacterium bovis is the causative agent of tuberculosis in a range of animal species and man, with worldwide annual losses to agriculture of $3 billion. The human burden of tuberculosis caused by...
Pickard, Derek, Wain, John, Baker, Stephen, Line, Alexandra, Chohan, Sonia, Fookes, Maria, ...
Vi capsular polysaccharide production is encoded by the viaB locus, which has a limited distribution in Salmonella enterica serovars. In S. enterica serovar Typhi, viaB is encoded on a 134-kb...
Wain, John, Diem Nga, L. T., Kidgell, Claire, James, Keith, Fortune, Sarah, Song Diep, To, ...
The first outbreak of multidrug-resistant (MDR) typhoid fever in Vietnam was in 1993, and by 1995 nearly 90% of cases were MDR. Plasmid HCM1, sequenced in full, is an incHI1 plasmid from Salmonella...
GeneDB: a resource for prokaryotic and eukaryotic organisms
Hertz-Fowler, Christiane, Peacock, Chris S., Wood, Valerie, Aslett, Martin, Kerhornou, Arnaud, Mooney, Paul, ...
GeneDB (http://www.genedb.org/) is a genome database for prokaryotic and eukaryotic organisms. The resource provides a portal through which data generated by the Pathogen Sequencing Unit at the...
Dorrell, Nick, Mangan, Joseph A., Laing, Kenneth G., Hinds, Jason, Linton, Dennis, Al-Ghusein, Hasan, ...
Campylobacter jejuni is the leading cause of bacterial food-borne diarrhoeal disease throughout the world, and yet is still a poorly understood pathogen. Whole genome microarray comparisons of 11 C....
Liu, Minghsun, Gingery, Mari, Doulatov, Sergei R., Liu, Yichin, Hodes, Asher, Baker, Stephen, ...
Liu et al. recently described a group of related temperate bacteriophages that infect Bordetella subspecies and undergo a unique template-dependent, reverse transcriptase-mediated tropism switching...
Baldwin, Adam, Sokol, Pamela A., Parkhill, Julian, Mahenthiralingam, Eshwar
The Burkholderia cepacia epidemic strain marker (BCESM) is a useful epidemiological marker for virulent B. cenocepacia strains that infect patients with cystic fibrosis. However, there was no...
Brugirard-Ricaud, Karine, Givaudan, Alain, Parkhill, Julian, Boemare, Noel, Kunst, Frank, Zumbihl, Robert, ...
Entomopathogenic bacteria of the genus Photorhabdus harbor a type III secretion system. This system was probably acquired prior to the separation of the species within this genus. Furthermore, the...
Holden, Matthew T. G., Feil, Edward J., Lindsay, Jodi A., Peacock, Sharon J., Day, Nicholas P. J., Enright, Mark C., ...
Staphylococcus aureus is an important nosocomial and community-acquired pathogen. Its genetic plasticity has facilitated the evolution of many virulent and drug-resistant strains, presenting a major...
Genomic plasticity of the causative agent of melioidosis, Burkholderia pseudomallei
Holden, Matthew T. G., Titball, Richard W., Peacock, Sharon J., Cerdeño-Tárraga, Ana M., Atkins, Timothy, Crossman, Lisa C., ...
Burkholderia pseudomallei is a recognized biothreat agent and the causative agent of melioidosis. This Gram-negative bacterium exists as a soil saprophyte in melioidosis-endemic areas of the world...
Rhodes, Glenn, Parkhill, Julian, Bird, Christine, Ambrose, Kerrie, Jones, Matthew C., Huys, Geert, ...
This study presents the first complete sequence of an IncU plasmid, pFBAOT6. This plasmid was originally isolated from a strain of Aeromonas caviae from hospital effluent (Westmorland General...
Microevolution and history of the plague bacillus, Yersinia pestis
Achtman, Mark, Morelli, Giovanna, Zhu, Peixuan, Wirth, Thierry, Diehl, Ines, Kusecek, Barica, ...
The association of historical plague pandemics with Yersinia pestis remains controversial, partly because the evolutionary history of this largely monomorphic bacterium was unknown. The...
Ren, Chuan-Peng, Beatson, Scott A., Parkhill, Julian, Pallen, Mark J.
Escherichia coli K-12 possesses two adjacent, divergent, promoterless flagellar genes, fhiA-mbhA, that are absent from Salmonella enterica. Through bioinformatics analysis, we found that these genes...
Thomson, Nicholas R., Yeats, Corin, Bell, Kenneth, Holden, Matthew T.G., Bentley, Stephen D., Livingstone, Morag, ...
The obligate intracellular bacterial pathogen Chlamydophila abortus strain S26/3 (formerly the abortion subtype of Chlamydia psittaci) is an important cause of late gestation abortions in ruminants...
The pCoo Plasmid of Enterotoxigenic Escherichia coli Is a Mosaic Cointegrate†
Froehlich, Barbara, Parkhill, Julian, Sanders, Mandy, Quail, Michael A., Scott, June R.
CS1 is the prototype of a class of pili of enterotoxigenic Escherichia coli (ETEC) associated with diarrheal disease in humans. The genes encoding this pilus are carried on a large plasmid, pCoo. We...
Genetic Analysis of the Capsular Biosynthetic Locus from All 90 Pneumococcal Serotypes
Bentley, Stephen D, Aanensen, David M, Mavroidi, Angeliki, Saunders, David, Rabbinowitsch, Ester, Collins, Matthew, ...
Several major invasive bacterial pathogens are encapsulated. Expression of a polysaccharide capsule is essential for survival in the blood, and thus for virulence, but also is a target for host...
The genome of Rhizobium leguminosarum has recognizable core and accessory components
Young, J Peter W, Crossman, Lisa C, Johnston, Andrew WB, Thomson, Nicholas R, Ghazoui, Zara F, Hull, Katherine H, ...
The genome sequence of the α-proteobacterial N2-fixing symbiont of legumes, Rhizobium leguminosarum, is described, revealing a 'core' and an 'accessory' component.
Multireplicon genome architecture of Lactobacillus salivarius
Claesson, Marcus J., Li, Yin, Leahy, Sinead, Canchaya, Carlos, Van Pijkeren, Jan Peter, Cerdeño-Tárraga, Ana M., ...
Lactobacillus salivarius subsp. salivarius strain UCC118 is a bacteriocin-producing strain with probiotic characteristics. The 2.13-Mb genome was shown by sequencing to comprise a 1.83 Mb chromosome,...
Phylogenetic Relationships of the Wolbachia of Nematodes and Arthropods
Fenn, Katelyn, Conlon, Claire, Jones, Martin, Quail, Michael A, Holroyd, Nancy E, Parkhill, Julian, ...
Wolbachia are well known as bacterial symbionts of arthropods, where they are reproductive parasites, but have also been described from nematode hosts, where the symbiotic interaction has features of...
Sebaihia, Mohammed, Preston, Andrew, Maskell, Duncan J., Kuzmiak, Holly, Connell, Terry D., King, Natalie D., ...
Bordetella avium is a pathogen of poultry and is phylogenetically distinct from Bordetella bronchiseptica, Bordetella pertussis, and Bordetella parapertussis, which are other species in the...
Prentice, Michael B., James, Keith D., Parkhill, Julian, Baker, Stephen G., Stevens, Kim, Simmonds, Mark N., ...
Population genetic studies suggest that Yersinia pestis, the cause of plague, is a clonal pathogen that has recently emerged from Yersinia pseudotuberculosis. Plasmid acquisition is likely to have...
Genetic Basis for Lipopolysaccharide O-Antigen Biosynthesis in Bordetellae
Preston, Andrew, Allen, Andrew G., Cadisch, Joanna, Thomas, Richard, Stevens, Kim, Churcher, Carol M., ...
Bordetella bronchiseptica and Bordetella parapertussis express a surface polysaccharide, attached to a lipopolysaccharide, which has been called O antigen. This structure is absent from Bordetella...
Salmonella enterica Serovar Typhi Possesses a Unique Repertoire of Fimbrial Gene Sequences
Townsend, Stacy M., Kramer, Naomi E., Edwards, Robert, Baker, Stephen, Hamlin, Nancy, Simmonds, Mark, ...
Salmonella enterica serotype Typhi differs from nontyphoidal Salmonella serotypes by its strict host adaptation to humans and higher primates. Since fimbriae have been implicated in host adaptation,...
McClelland, Michael, Florea, Liliana, Sanderson, Ken, Clifton, Sandra W., Parkhill, Julian, Churcher, Carol, ...
The Escherichia coli K-12 genome (ECO) was compared with the sampled genomes of the sibling species Salmonella enterica serovars Typhimurium, Typhi and Paratyphi A (collectively referred to as SAL)...
Berry, Colin, O'Neil, Susan, Ben-Dov, Eitan, Jones, Andrew F., Murphy, Lee, Quail, Michael A., ...
The entire 127,923-bp sequence of the toxin-encoding plasmid pBtoxis from Bacillus thuringiensis subsp. israelensis is presented and analyzed. In addition to the four known Cry and two known Cyt...
The complete genome sequence of Mycobacterium bovis
Garnier, Thierry, Eiglmeier, Karin, Camus, Jean-Christophe, Medina, Nadine, Mansoor, Huma, Pryor, Melinda, ...
Mycobacterium bovis is the causative agent of tuberculosis in a range of animal species and man, with worldwide annual losses to agriculture of $3 billion. The human burden of tuberculosis caused by...
Pickard, Derek, Wain, John, Baker, Stephen, Line, Alexandra, Chohan, Sonia, Fookes, Maria, ...
Vi capsular polysaccharide production is encoded by the viaB locus, which has a limited distribution in Salmonella enterica serovars. In S. enterica serovar Typhi, viaB is encoded on a 134-kb...
Wain, John, Diem Nga, L. T., Kidgell, Claire, James, Keith, Fortune, Sarah, Song Diep, To, ...
The first outbreak of multidrug-resistant (MDR) typhoid fever in Vietnam was in 1993, and by 1995 nearly 90% of cases were MDR. Plasmid HCM1, sequenced in full, is an incHI1 plasmid from Salmonella...
GeneDB: a resource for prokaryotic and eukaryotic organisms
Hertz-Fowler, Christiane, Peacock, Chris S., Wood, Valerie, Aslett, Martin, Kerhornou, Arnaud, Mooney, Paul, ...
GeneDB (http://www.genedb.org/) is a genome database for prokaryotic and eukaryotic organisms. The resource provides a portal through which data generated by the Pathogen Sequencing Unit at the...
Dorrell, Nick, Mangan, Joseph A., Laing, Kenneth G., Hinds, Jason, Linton, Dennis, Al-Ghusein, Hasan, ...
Campylobacter jejuni is the leading cause of bacterial food-borne diarrhoeal disease throughout the world, and yet is still a poorly understood pathogen. Whole genome microarray comparisons of 11 C....
Liu, Minghsun, Gingery, Mari, Doulatov, Sergei R., Liu, Yichin, Hodes, Asher, Baker, Stephen, ...
Liu et al. recently described a group of related temperate bacteriophages that infect Bordetella subspecies and undergo a unique template-dependent, reverse transcriptase-mediated tropism switching...
Baldwin, Adam, Sokol, Pamela A., Parkhill, Julian, Mahenthiralingam, Eshwar
The Burkholderia cepacia epidemic strain marker (BCESM) is a useful epidemiological marker for virulent B. cenocepacia strains that infect patients with cystic fibrosis. However, there was no...
Brugirard-Ricaud, Karine, Givaudan, Alain, Parkhill, Julian, Boemare, Noel, Kunst, Frank, Zumbihl, Robert, ...
Entomopathogenic bacteria of the genus Photorhabdus harbor a type III secretion system. This system was probably acquired prior to the separation of the species within this genus. Furthermore, the...
Holden, Matthew T. G., Feil, Edward J., Lindsay, Jodi A., Peacock, Sharon J., Day, Nicholas P. J., Enright, Mark C., ...
Staphylococcus aureus is an important nosocomial and community-acquired pathogen. Its genetic plasticity has facilitated the evolution of many virulent and drug-resistant strains, presenting a major...
Genomic plasticity of the causative agent of melioidosis, Burkholderia pseudomallei
Holden, Matthew T. G., Titball, Richard W., Peacock, Sharon J., Cerdeño-Tárraga, Ana M., Atkins, Timothy, Crossman, Lisa C., ...
Burkholderia pseudomallei is a recognized biothreat agent and the causative agent of melioidosis. This Gram-negative bacterium exists as a soil saprophyte in melioidosis-endemic areas of the world...
Rhodes, Glenn, Parkhill, Julian, Bird, Christine, Ambrose, Kerrie, Jones, Matthew C., Huys, Geert, ...
This study presents the first complete sequence of an IncU plasmid, pFBAOT6. This plasmid was originally isolated from a strain of Aeromonas caviae from hospital effluent (Westmorland General...
Microevolution and history of the plague bacillus, Yersinia pestis
Achtman, Mark, Morelli, Giovanna, Zhu, Peixuan, Wirth, Thierry, Diehl, Ines, Kusecek, Barica, ...
The association of historical plague pandemics with Yersinia pestis remains controversial, partly because the evolutionary history of this largely monomorphic bacterium was unknown. The...
Ren, Chuan-Peng, Beatson, Scott A., Parkhill, Julian, Pallen, Mark J.
Escherichia coli K-12 possesses two adjacent, divergent, promoterless flagellar genes, fhiA-mbhA, that are absent from Salmonella enterica. Through bioinformatics analysis, we found that these genes...