Thesis (M.S.)--University of Kansas, Nurse Anesthesia, 1995.
Single-Dose Pharmacokinetics of Indinavir and the Effect of Food
Yeh, Kuang C., Deutsch, Paul J., Haddix, Heidi, Hesney, Michael, Hoagland, Vicki, Ju, William D., ...
Indinavir sulfate is a human immunodeficiency virus type 1 (HIV-1) protease inhibitor indicated for treatment of HIV infection and AIDS in adults. The purpose of this report is to summarize...
Single-Dose Pharmacokinetics of Indinavir and the Effect of Food
Yeh, Kuang C., Deutsch, Paul J., Haddix, Heidi, Hesney, Michael, Hoagland, Vicki, Ju, William D., ...
Single- and Multiple-Dose Pharmacokinetics of Caspofungin in Healthy Men
Stone, Julie A., Holland, Sherry D., Wickersham, Peter J., Sterrett, Andrew, Schwartz, Michael, Bonfiglio, Cynthia, ...
Caspofungin, a glucan synthesis inhibitor, is being developed as a parenteral antifungal agent. The pharmacokinetics of caspofungin following 1-h intravenous infusions in healthy men was investigated...
Disposition of Caspofungin: Role of Distribution in Determining Pharmacokinetics in Plasma
Stone, Julie A., Xu, Xin, Winchell, Gregory A., Deutsch, Paul J., Pearson, Paul G., Migoya, Elizabeth M., ...
The disposition of caspofungin, a parenteral antifungal drug, was investigated. Following a single, 1-h, intravenous infusion of 70 mg (200 μCi) of [3H]caspofungin to healthy men, plasma, urine, and...
Potential for Interactions between Caspofungin and Nelfinavir or Rifampin
Stone, Julie A., Migoya, Elizabeth M., Hickey, Lisa, Winchell, Gregory A., Deutsch, Paul J., Ghosh, Kalyan, ...
The potential for interactions between caspofungin and nelfinavir or rifampin was evaluated in two parallel-panel studies. In study A, healthy subjects received a 14-day course of caspofungin alone...
Pharmacokinetics, Safety, and Tolerability of Caspofungin in Children and Adolescents
Walsh, Thomas J., Adamson, Peter C., Seibel, Nita L., Flynn, Patricia M., Neely, Michael N., Schwartz, Cindy, ...
Caspofungin is a parenteral antifungal that inhibits beta-1,3-d-glucan synthesis. Although licensed for adult use, the appropriate caspofungin dosing regimen in pediatric patients is not yet known....
Single-Dose Pharmacokinetics of Indinavir and the Effect of Food
Yeh, Kuang C., Deutsch, Paul J., Haddix, Heidi, Hesney, Michael, Hoagland, Vicki, Ju, William D., ...
Indinavir sulfate is a human immunodeficiency virus type 1 (HIV-1) protease inhibitor indicated for treatment of HIV infection and AIDS in adults. The purpose of this report is to summarize...
Single-Dose Pharmacokinetics of Indinavir and the Effect of Food
Yeh, Kuang C., Deutsch, Paul J., Haddix, Heidi, Hesney, Michael, Hoagland, Vicki, Ju, William D., ...
Single- and Multiple-Dose Pharmacokinetics of Caspofungin in Healthy Men
Stone, Julie A., Holland, Sherry D., Wickersham, Peter J., Sterrett, Andrew, Schwartz, Michael, Bonfiglio, Cynthia, ...
Caspofungin, a glucan synthesis inhibitor, is being developed as a parenteral antifungal agent. The pharmacokinetics of caspofungin following 1-h intravenous infusions in healthy men was investigated...
Disposition of Caspofungin: Role of Distribution in Determining Pharmacokinetics in Plasma
Stone, Julie A., Xu, Xin, Winchell, Gregory A., Deutsch, Paul J., Pearson, Paul G., Migoya, Elizabeth M., ...
The disposition of caspofungin, a parenteral antifungal drug, was investigated. Following a single, 1-h, intravenous infusion of 70 mg (200 μCi) of [3H]caspofungin to healthy men, plasma, urine, and...
Potential for Interactions between Caspofungin and Nelfinavir or Rifampin
Stone, Julie A., Migoya, Elizabeth M., Hickey, Lisa, Winchell, Gregory A., Deutsch, Paul J., Ghosh, Kalyan, ...
The potential for interactions between caspofungin and nelfinavir or rifampin was evaluated in two parallel-panel studies. In study A, healthy subjects received a 14-day course of caspofungin alone...
Pharmacokinetics, Safety, and Tolerability of Caspofungin in Children and Adolescents
Walsh, Thomas J., Adamson, Peter C., Seibel, Nita L., Flynn, Patricia M., Neely, Michael N., Schwartz, Cindy, ...
Caspofungin is a parenteral antifungal that inhibits beta-1,3-d-glucan synthesis. Although licensed for adult use, the appropriate caspofungin dosing regimen in pediatric patients is not yet known....
Lack of a Significant Drug Interaction between Raltegravir and Tenofovir▿
Wenning, Larissa A., Friedman, Evan J., Kost, James T., Breidinger, Sheila A., Stek, Jon E., Lasseter, Kenneth C., ...
Raltegravir is a novel human immunodeficiency virus type 1 (HIV-1) integrase inhibitor with potent in vitro activity (95% inhibitory concentration of 31 nM in 50% human serum). This article reports...
Minimal Effects of Ritonavir and Efavirenz on the Pharmacokinetics of Raltegravir▿
Iwamoto, Marian, Wenning, Larissa A., Petry, Amelia S., Laethem, Martine, De Smet, Marina, Kost, James T., ...
Raltegravir is a novel human immunodeficiency virus type 1 (HIV-1) integrase strand transfer inhibitor with potent in vitro activity against HIV-1 (95% inhibitory concentration = 31 nM in 50% human...
Anderson, Matt S., Kakuda, Thomas N., Hanley, William, Miller, Jutta, Kost, James T., Stoltz, Randall, ...
Etravirine, a next-generation nonnucleoside reverse transcriptase inhibitor, and raltegravir, an integrase strand transfer inhibitor, have separately demonstrated potent activity in...
Pharmacokinetics and Safety of Caspofungin in Neonates and Infants Less than 3 Months of Age▿
Sáez-Llorens, Xavier, Macias, Mercedes, Maiya, Padmanabha, Pineros, Juan, Jafri, Hasan S., Chatterjee, Archana, ...
Candida infections represent a major threat in neonatal intensive care units. This is the first prospective study to obtain caspofungin plasma levels and safety data for neonates and very young...
Pharmacokinetics and Safety of Caspofungin in Older Infants and Toddlers ▿
Neely, Michael, Jafri, Hasan S., Seibel, Nita, Knapp, Katherine, Adamson, Peter C., Bradshaw, Susan K., ...
Although information about the efficacy and safety experience with caspofungin at 50 mg/m2 daily is available for children and adolescents, the dosing regimen in infants and toddlers 3 to 24 months...
Iwamoto, Marian, Hanley, William D., Petry, Amelia S., Friedman, Evan J., Kost, James T., Breidinger, Sheila A., ...
Raltegravir is a human immunodeficiency virus type 1 integrase strand transfer inhibitor with potent activity in vitro and in vivo. Raltegravir is primarily cleared by hepatic metabolism via...