Chromatin-based regulation of cytokine transcription in Th2 cells and mast cells (2005)
Monticelli, Silvia, Lee, Dong U., Nardone, Julie, Bolton, Diana L., Rao, Anjana
Th2 cells and mast cells are major sources of IL4, IL5 and IL13, cytokines that mediate immunity against parasites and are also central players in the pathophysiology of asthma, allergy and atopic...
Chromatin-based regulation of cytokine transcription in Th2 cells and mast cells (2005)
Monticelli, Silvia, Lee, Dong U., Nardone, Julie, Bolton, Diana L., Rao, Anjana
Th2 cells and mast cells are major sources of IL4, IL5 and IL13, cytokines that mediate immunity against parasites and are also central players in the pathophysiology of asthma, allergy and atopic...
Site-directed mutagenesis of a B2 bradykinin receptor / (1993)
Thesis (Ph. D.)--Harvard University, 1993.
A common phosphotyrosine signature for the Bcr-Abl kinase
Goss, Valerie L., Lee, Kimberly A., Moritz, Albrecht, Nardone, Julie, Spek, Erik J., MacNeill, Joan, ...
The Bcr-Abl fusion kinase drives oncogenesis in chronic myeloid leukemia (CML). CML patients are currently treated with the Abl tyrosine kinase inhibitor imatinib, which is effective in early stages...
Profiling of UV-induced ATM/ATR signaling pathways
Stokes, Matthew P., Rush, John, MacNeill, Joan, Ren, Jian Min, Sprott, Kam, Nardone, Julie, ...
To ensure survival in the face of genomic insult, cells have evolved complex mechanisms to respond to DNA damage, termed the DNA damage checkpoint. The serine/threonine kinases ataxia...
Signaling networks assembled by oncogenic EGFR and c-Met
Guo, Ailan, Villén, Judit, Kornhauser, Jon, Lee, Kimberly A., Stokes, Matthew P., Rikova, Klarisa, ...
A major question regarding the sensitivity of solid tumors to targeted kinase inhibitors is why some tumors respond and others do not. The observation that many tumors express EGF receptor (EGFR),...
Boccalatte, Francesco E., Voena, Claudia, Riganti, Chiara, Bosia, Amalia, D'Amico, Lucia, Riera, Ludovica, ...
Anaplastic large cell lymphoma represents a subset of neoplasms caused by translocations that juxtapose the anaplastic lymphoma kinase (ALK) to dimerization partners. The constitutive activation of...