Julie Piessevaux

The many faces of the SOCS box (2008)

Piessevaux, Julie, Lavens, Delphine, Peelman, Frank, Tavernier, Jan

The suppressors of cytokine signalling (SOCS) box is a structural domain found at the C-terminus of over 70 human proteins. It is usually coupled to a protein interaction module such as an SH2 domain...

SOCS proteins and cytokine signalling: the many faces of the SOCS box (2008)

Piessevaux, Julie

SOCS proteins are regulators of various signal transduction cascades that are essential to normal physiology. Important advances have been made in understanding their mode of action. However,...