Scientific Commons: Juliette K. Tinker

FimW Is a Negative Regulator Affecting Type 1 Fimbrial Expression in Salmonella enterica Serovar Typhimurium

Tinker, Juliette K., Hancox, Lisa S., Clegg, Steven

Type 1 fimbriae are proteinaceous surface appendages that carry adhesins specific for mannosylated glycoproteins. These fimbriae are found on most members of the family Enterobacteriaceae and are...

Characterization of FimY as a Coactivator of Type 1 Fimbrial Expression in Salmonella enterica Serovar Typhimurium

Tinker, Juliette K., Clegg, Steven

Type 1 fimbriae of Salmonella enterica serovar Typhimurium are surface appendages that carry adhesins specific for mannosylated host glycoconjugates. Regulation of the major fimbrial subunit is...

Cholera Holotoxin Assembly Requires a Hydrophobic Domain at the A-B5 Interface: Mutational Analysis and Development of an In Vitro Assembly System

Tinker, Juliette K., Erbe, Jarrod L., Hol, Wim G. J., Holmes, Randall K.

Cholera toxin (CT) and related Escherichia coli enterotoxins LTI and LTIIb have a conserved hydrophobic region at the AB5 interface postulated to be important for toxin assembly. Hydrophobic residue...

Characterization of Fluorescent Chimeras of Cholera Toxin and Escherichia coli Heat-Labile Enterotoxins Produced by Use of the Twin Arginine Translocation System

Tinker, Juliette K., Erbe, Jarrod L., Holmes, Randall K.

Cholera toxin (CT) is an AB5 toxin responsible for the profuse secretory diarrhea resulting from Vibrio cholerae infection. CT consists of a pentameric, receptor-binding B subunit (CTB) and a...