Junko K. Akada

In Vitro Anti-Helicobacter pylori Activities of New Rifamycin Derivatives, KRM-1648 and KRM-1657

Akada, Junko K., Shirai, Mutsunori, Fujii, Kenji, Okita, Kiwamu, Nakazawa, Teruko

The new rifamycin derivatives KRM-1657 and KRM-1648 were evaluated for their in vitro antimicrobial activities against 44 strains of Helicobacter pylori. Although the drugs were not very active...

Roles of FrxA and RdxA Nitroreductases of Helicobacter pylori in Susceptibility and Resistance to Metronidazole

Jeong, Jin-Yong, Mukhopadhyay, Asish K., Akada, Junko K., Dailidiene, Daiva, Hoffman, Paul S., Berg, Douglas E.

The relative importance of the frxA and rdxA nitroreductase genes of Helicobacter pylori in metronidazole (MTZ) susceptibility and resistance has been controversial. Jeong et al. (J. Bacteriol....

Nucleotide Sequence and Characterization of cdrA, a Cell Division-Related Gene of Helicobacter pylori

Takeuchi, Hiroaki, Shirai, Mutsunori, Akada, Junko K., Tsuda, Masataka, Nakazawa, Teruko

We identified cell division-related gene cdrA in Helicobacter pylori HPK5. The putative gene product, CdrA, is a 367-amino-acid polypeptide that exhibited a high level of homology to conserved...

In Vitro Anti-Helicobacter pylori Activities of New Rifamycin Derivatives, KRM-1648 and KRM-1657

Akada, Junko K., Shirai, Mutsunori, Fujii, Kenji, Okita, Kiwamu, Nakazawa, Teruko

The new rifamycin derivatives KRM-1657 and KRM-1648 were evaluated for their in vitro antimicrobial activities against 44 strains of Helicobacter pylori. Although the drugs were not very active...

Roles of FrxA and RdxA Nitroreductases of Helicobacter pylori in Susceptibility and Resistance to Metronidazole

Jeong, Jin-Yong, Mukhopadhyay, Asish K., Akada, Junko K., Dailidiene, Daiva, Hoffman, Paul S., Berg, Douglas E.

The relative importance of the frxA and rdxA nitroreductase genes of Helicobacter pylori in metronidazole (MTZ) susceptibility and resistance has been controversial. Jeong et al. (J. Bacteriol....

Nucleotide Sequence and Characterization of cdrA, a Cell Division-Related Gene of Helicobacter pylori

Takeuchi, Hiroaki, Shirai, Mutsunori, Akada, Junko K., Tsuda, Masataka, Nakazawa, Teruko

We identified cell division-related gene cdrA in Helicobacter pylori HPK5. The putative gene product, CdrA, is a 367-amino-acid polypeptide that exhibited a high level of homology to conserved...