Junlong Zhang

Maternal high fat diet during pregnancy and lactation alters hepatic expression of insulin like growth factor-2 and key microRNAs in the adult offspring (2009)

Zhang, Junlong, Zhang, Fang, Didelot, Xavier, Bruce, Kimberley D, Cagampang, Felino R, Vatish, Manu, ...

Abstract Background miRNAs play important roles in the regulation of gene functions. Maternal dietary modifications during pregnancy and gestation have long-term effects on the offspring, but it is...

Maternal high fat diet during pregnancy and lactation alters hepatic expression of insulin like growth factor-2 and key microRNAs in the adult offspring (2009)

Zhang, Junlong, Zhang, F. (Fang), Didelot, Xavier, Bruce, Kimberley D., Cagampang, Felino R., Vatish, Manu, ...

Background miRNAs play important roles in the regulation of gene functions. Maternal dietary modifications during pregnancy and gestation have long-term effects on the offspring, but it is not known...

Maternal low protein diet restricted to the preimplantation period induces a gender-specific change on hepatic gene expression in rat fetuses (2007)

Kwong, Wing Yee, Miller, Daniel J., Wilkins, Adrian P., Dear, Mark S., Wright, J. Neville, Osmond, Clive, ...

It has been shown previously that maternal low protein diet (LPD) throughout rat gestation altered hepatic gene expression and enzyme activities in offspring. Here, we investigate the effect of...

Adipocyte differentiation induced using nonspecific siRNA controls in cultured human mesenchymal stem cells (2007)

Xu, Yunhe, Mirmalek-Sani, Sayed-Hadi, Lin, Feng, Zhang, Junlong, Oreffo, Richard O.C.

RNA interference (RNAi) is gene silencing induced by double-stranded RNA of 21-23 nucleotides in length, termed small interfering RNA, or siRNA. RNAi-based techniques have been widely applied to...

Adipocyte differentiation induced using nonspecific siRNA controls in cultured human mesenchymal stem cells (2007)

Xu, Yunhe, Mirmalek-Sani, Sayed-Hadi, Lin, Feng, Zhang, Junlong, Oreffo, Richard O.C.

RNA interference (RNAi) is gene silencing induced by double-stranded RNA of 21–23 nucleotides in length, termed small interfering RNA, or siRNA. RNAi-based techniques have been widely applied to...

Maternal low protein diet restricted to the preimplantation period induces a gender-specific change on hepatic gene expression in rat fetuses (2007)

Kwong, Wing Yee, Miller, Daniel J., Wilkins, Adrian P., Dear, Mark S., Wright, J. Neville, Osmond, Clive, ...

It has been shown previously that maternal low protein diet (LPD) throughout rat gestation altered hepatic gene expression and enzyme activities in offspring. Here, we investigate the effect of...

Expression of AdipoR1 in vivo in skeletal muscle is independently associated with measures of truncal obesity in middle-aged Caucasian men (2005)

Zhang, Junlong, Holt, Helen, Wang, Chunli, Hadid, Omar H., Byrne, Christopher D.

The insulin-sensitizing effect of adiponectin (1–4) is mediated via adiponectin receptors (AdipoR1 and AdipoR2) (5). AdipoR1 is abundantly expressed in skeletal muscle, whereas AdipoR2 is also...

Maternal dietary iron restriction modulates hepatic lipid metabolism in the fetuses (2005)

Zhang, Junlong, Lewis, Rohan M., Wang, Chunli, Hales, Nicholas, Byrne, Christopher D.

Maternal dietary Fe restriction reduced fasting plasma cholesterol and triglyceride (TG) concentrations in the fetuses, as well as decreased plasma TG levels in the adult offspring. To investigate...

High-unsaturated-fat, high-protein, and low-carbohydrate diet during pregnancy and lactation modulates hepatic lipid metabolism in female adult offspring (2005)

Zhang, Junlong, Wang, Chunli, Terroni, Paul L., Cagampang, Felino R.A., Hanson, Mark, Byrne, Christopher D.

Whether a high-unsaturated-fat, high-protein (HFP), and low-carbohydrate (CHO) diet during gestation has long-lasting beneficial effects on lipid metabolism in the offspring was investigated using a...

Letters: observations. Plasma adiponectin concentrations are independently predicted by fat insulin sensitivity in women and by muscle insulin sensitivity in men (2005)

Zhang, Junlong, Holt, Richard I.G., Wild, Sarah H., Poole, Ruth B., Holt, Helen, Byrne, Christopher D.

Adiponectin is an abundant plasma protein, mainly secreted by adipocytes and closely linked to insulin sensitivity (1–4). Plasma adiponectin independently correlates with insulin sensitivity (5)....

Insulin and human chorionic gonadotropin cause a shift in the balance of sterol regulatory element-binding protein (SREBP) isoforms toward the SREBP-1c isoform in cultures of human granulosa cells (2005)

Richardson, Malcolm C., Cameron, Iain T., Simonis, Chantal D., Das, Madhab C., Hodge, Tessa E., Zhang, Junlong, ...

The isoforms of sterol regulatory element-binding proteins (SREBP) (1a, 1c, and 2) are key transcriptional regulators of lipid biosynthesis. We examined their regulation by gonadotropin and insulin...

Macromolecular ruthenium porphyrin catalysts for organic transformation reactions : mechanistic and catalytic studies (2005)

Zhang, Junlong

(Uncorrected OCR) Abstract of thesis entitled MACROMOLECULAR RUTHENIUM PORPHYRIN CATALYSTS FOR ORGANIC TRANSFORMATION REACTIONS: MECHANISTIC AND CATALYTIC STUDIES Submitted by Zhang Jun-Long for the...

Macromolecular ruthenium porphyrin catalysts for organic transformation reactions : mechanistic and catalytic studies (2005)

Zhang, Junlong

(Uncorrected OCR) Abstract of thesis entitled MACROMOLECULAR RUTHENIUM PORPHYRIN CATALYSTS FOR ORGANIC TRANSFORMATION REACTIONS: MECHANISTIC AND CATALYTIC STUDIES Submitted by Zhang Jun-Long for the...

Macromolecular ruthenium porphyrin catalysts for organic transformation reactions : mechanistic and catalytic studies (2005)

Zhang, Junlong

(Uncorrected OCR) Abstract of thesis entitled MACROMOLECULAR RUTHENIUM PORPHYRIN CATALYSTS FOR ORGANIC TRANSFORMATION REACTIONS: MECHANISTIC AND CATALYTIC STUDIES Submitted by Zhang Jun-Long for the...

Engagement of αvβ3 integrin regulates proliferation and apoptosis of hepatic stellate cells (2004)

Zhou, Xiaoying, Murphy, Frank R., Gehdu, Nitu, Zhang, Junlong, Iredale, John P., Benyon, R. Christopher

Hepatic stellate cells are the major source of the extracellular matrix that accumulates in fibrotic liver. During progressive liver fibrosis, hepatic stellate cells proliferate, but during...

A novel medium throughput quantitative competitive PCR technology to simultaneously measure mRNA levels from multiple genes (2002)

Zhang, Junlong, Day, Ian N.M., Byrne, Christopher D.

There is a great demand for technologies to simultaneously measure mRNA levels from multiple genes. Here we report a new quantitative competitive PCR technology and demonstrate simultaneous...

A novel medium throughput quantitative competitive PCR technology to simultaneously measure mRNA levels from multiple genes (2002)

Zhang, Junlong, Day, Ian N.M., Byrne, Christopher D.

There is a great demand for technologies to simultaneously measure mRNA levels from multiple genes. Here we report a new quantitative competitive PCR technology and demonstrate simultaneous...

A novel medium throughput quantitative competitive PCR technology to simultaneously measure mRNA levels from multiple genes (2002)

Zhang, Junlong, Day, Ian N.M., Byrne, Christopher D.

There is a great demand for technologies to simultaneously measure mRNA levels from multiple genes. Here we report a new quantitative competitive PCR technology and demonstrate simultaneous...

A novel medium throughput quantitative competitive PCR technology to simultaneously measure mRNA levels from multiple genes (2002)

Zhang, Junlong, Day, Ian N. M., Byrne, Christopher D.

There is a great demand for technologies to simultaneously measure mRNA levels from multiple genes. Here we report a new quantitative competitive PCR technology and demonstrate simultaneous...

A novel medium throughput quantitative competitive PCR technology to simultaneously measure mRNA levels from multiple genes

Zhang, Junlong, Day, Ian N. M., Byrne, Christopher D.

There is a great demand for technologies to simultaneously measure mRNA levels from multiple genes. Here we report a new quantitative competitive PCR technology and demonstrate simultaneous...

Dampening the silencing effect of RNA interference in mammals

Zhang, Junlong

RNAi (RNA interference) refers to the suppression of expression of a target gene (mainly at the post-transcriptional or translational level) induced by small (21–23 nucleotides) RNA molecules,...

A novel medium throughput quantitative competitive PCR technology to simultaneously measure mRNA levels from multiple genes

Zhang, Junlong, Day, Ian N. M., Byrne, Christopher D.

There is a great demand for technologies to simultaneously measure mRNA levels from multiple genes. Here we report a new quantitative competitive PCR technology and demonstrate simultaneous...

Dampening the silencing effect of RNA interference in mammals

Zhang, Junlong

RNAi (RNA interference) refers to the suppression of expression of a target gene (mainly at the post-transcriptional or translational level) induced by small (21–23 nucleotides) RNA molecules,...

Adipocyte differentiation induced using nonspecific siRNA controls in cultured human mesenchymal stem cells

Xu, Yunhe, Mirmalek-Sani, Sayed-Hadi, Lin, Feng, Zhang, Junlong, Oreffo, Richard O.C.

RNA interference (RNAi) is gene silencing induced by double-stranded RNA of 21–23 nucleotides in length, termed small interfering RNA, or siRNA. RNAi-based techniques have been widely applied to...