The Aerobiology Mission: Develop appropriate animal models; define pathogenesis/mechanism of toxicity/toxicology, develop surrogate markers of efficacy; Develop new bioaerosol technologies; precision...
Heine, Henry S., Bassett, Jennifer, Miller, Lynda, Hartings, Justin M., Ivins, Bruce E., Pitt, M. Louise, ...
An anthrax spore aerosol infection mouse model was developed as a first test of in vivo efficacy of antibiotics identified as active against Bacillus anthracis. Whole-body, 50% lethal dose (LD50)...