Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana (1999)
Schüller, C, Wambutt, R, Murphy, G, Pohl, T, ...
The higher plant Arabidopsis thaliana (Arabidopsis) is an important model for identifying plant genes and determining their function. To assist biological investigations and to define chromosome...
The complete genome sequence of the Gram-positive bacterium Bacillus subtilis (1997)
Kunst, F., Ogasawara, N., Moszer, I., Albertini, A.M., Alloni, G., Azevedo, V., ...
Bacillus subtilis is the best-characterized member of the Gram-positive bacteria. Its genome of 4,214,810 base pairs comprises 4,100 protein-coding genes. Of these protein-coding genes, 53% are...
Genes involved in immunity to the lantibiotic nisin produced by Lactococcus lactis 6F3.
The lantibiotic nisin is produced by several strains of Lactococcus lactis. The complete gene cluster for nisin biosynthesis in L. lactis 6F3 comprises 15 kb of DNA. As described previously, the...
Evidence for a multimeric subtilin synthetase complex.
Kiesau, P, Eikmanns, U, Gutowski-Eckel, Z, Weber, S, Hammelmann, M, Entian, K D
Subtilin is a lanthionine-containing peptide antibiotic (lantibiotic) produced by Bacillus subtilis. It is ribosomally synthesized as a prepeptide and modified posttranslationally. Three proteins of...
Engelke, G, Gutowski-Eckel, Z, Hammelmann, M, Entian, K D
Nisin produced by Lactococcus lactis 6F3 is used as a food preservative and is the most important member of a group of peptide-antibiotics containing lanthionine bridges (lantibiotics) (N. Schnell,...
Analysis of genes involved in biosynthesis of the lantibiotic subtilin.
Klein, C, Kaletta, C, Schnell, N, Entian, K D
Lantibiotics are peptide-derived antibiotics with high antimicrobial activity against pathogenic gram-positive bacteria. They are ribosomally synthesized and posttranslationally modified (N. Schnell,...
Gutowski-Eckel, Z, Klein, C, Siegers, K, Bohm, K, Hammelmann, M, Entian, K D
The information responsible for biosynthesis of the lantibiotic subtilin is organized in an operon-like structure that starts with the spaB gene. The spaB gene encodes an open reading frame...
Regulation of nisin biosynthesis and immunity in Lactococcus lactis 6F3.
Engelke, G, Gutowski-Eckel, Z, Kiesau, P, Siegers, K, Hammelmann, M, Entian, K D
The biosynthetic genes of the nisin-producing strain Lactococcus lactis 6F3 are organized in an operon-like structure starting with the structural gene nisA followed by the genes nisB, nisT, and...
Subtilin is a ribosomally synthesized peptide antibiotic produced by Bacillus subtilis ATCC 6633. Recently, we reported regarding genes spaB, spaT, and spaC (C. Klein, C. Kaletta, N. Schnell, and...
Klein, C, Kaletta, C, Entian, K D
Subtilin is a lanthionine-containing peptide antibiotic (lantibiotic) which is produced by Bacillus subtilis ATCC 6633. Upstream from the structural gene of subtilin, spaS, three genes (spaB, spaT,...
Ochs, D, Kaletta, C, Entian, K D, Beck-Sickinger, A, Poralla, K
The pentacyclic hopanoids, a class of eubacterial lipids, are synthesized by squalene-hopene cyclase and side chain-elongating enzymes. With the aid of DNA probes based on the amino-terminal sequence...
Saccharomyces cerevisiae regulatory genes CAT1 and CAT3 constitute a positive control circuit necessary for derepression of gluconeogenic and disaccharide-utilizing enzymes. Mutations within these...
Nisin produced by Streptococcus lactis is used as a food preservative and is the most important member of a group of antibiotics containing lanthionine bridges. To understand the genetic basis of...
A selection system has been devised for isolating hexokinase PII structural gene mutants that cause defects in carbon catabolite repression, but retain normal catalytic activity. We used diploid...
A mutation causing resistance to carbon catabolite repression in gene HEX2, mutant allele hex2-3, causes an extreme sensitivity to maltose when in combination with the genes necessary for maltose...
Hedges, D, Proft, M, Entian, K D
The expression of gluconeogenic fructose-1,6-bisphosphatase (encoded by the FBP1 gene) depends on the carbon source. Analysis of the FBP1 promoter revealed two upstream activating elements, UAS1FBP1...
Randez-Gil, F, Bojunga, N, Proft, M, Entian, K D
The Cat8p zinc cluster protein is essential for growth of Saccharomyces cerevisiae with nonfermentable carbon sources. Expression of the CAT8 gene is subject to glucose repression mainly caused by...
Entian, K D, Hilberg, F, Opitz, H, Mecke, D
The regulatory hexokinase PII mutants isolated previously (K.-D. Entian and K.-U. Fröhlich, J. Bacteriol. 158:29-35, 1984) were characterized further. These mutants were defective in glucose...
CAT5, a new gene necessary for derepression of gluconeogenic enzymes in Saccharomyces cerevisiae.
Proft, M, Kötter, P, Hedges, D, Bojunga, N, Entian, K D
PCK1 encoding phosphoenolpyruvate carboxykinase is transcriptionally regulated by two upstream activating elements. By screening for mutants that failed to derepress a UAS2PCK1-CYC1-lacZ reporter...
Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X.
Galibert, F, Alexandraki, D, Baur, A, Boles, E, Chalwatzis, N, Chuat, J C, ...
The complete nucleotide sequence of Saccharomyces cerevisiae chromosome X (745 442 bp) reveals a total of 379 open reading frames (ORFs), the coding region covering approximately 75% of the entire...
Genes involved in immunity to the lantibiotic nisin produced by Lactococcus lactis 6F3.
The lantibiotic nisin is produced by several strains of Lactococcus lactis. The complete gene cluster for nisin biosynthesis in L. lactis 6F3 comprises 15 kb of DNA. As described previously, the...
Evidence for a multimeric subtilin synthetase complex.
Kiesau, P, Eikmanns, U, Gutowski-Eckel, Z, Weber, S, Hammelmann, M, Entian, K D
Subtilin is a lanthionine-containing peptide antibiotic (lantibiotic) produced by Bacillus subtilis. It is ribosomally synthesized as a prepeptide and modified posttranslationally. Three proteins of...
Engelke, G, Gutowski-Eckel, Z, Hammelmann, M, Entian, K D
Nisin produced by Lactococcus lactis 6F3 is used as a food preservative and is the most important member of a group of peptide-antibiotics containing lanthionine bridges (lantibiotics) (N. Schnell,...
Analysis of genes involved in biosynthesis of the lantibiotic subtilin.
Klein, C, Kaletta, C, Schnell, N, Entian, K D
Lantibiotics are peptide-derived antibiotics with high antimicrobial activity against pathogenic gram-positive bacteria. They are ribosomally synthesized and posttranslationally modified (N. Schnell,...
Gutowski-Eckel, Z, Klein, C, Siegers, K, Bohm, K, Hammelmann, M, Entian, K D
The information responsible for biosynthesis of the lantibiotic subtilin is organized in an operon-like structure that starts with the spaB gene. The spaB gene encodes an open reading frame...
Regulation of nisin biosynthesis and immunity in Lactococcus lactis 6F3.
Engelke, G, Gutowski-Eckel, Z, Kiesau, P, Siegers, K, Hammelmann, M, Entian, K D
The biosynthetic genes of the nisin-producing strain Lactococcus lactis 6F3 are organized in an operon-like structure starting with the structural gene nisA followed by the genes nisB, nisT, and...
Subtilin is a ribosomally synthesized peptide antibiotic produced by Bacillus subtilis ATCC 6633. Recently, we reported regarding genes spaB, spaT, and spaC (C. Klein, C. Kaletta, N. Schnell, and...
Klein, C, Kaletta, C, Entian, K D
Subtilin is a lanthionine-containing peptide antibiotic (lantibiotic) which is produced by Bacillus subtilis ATCC 6633. Upstream from the structural gene of subtilin, spaS, three genes (spaB, spaT,...
Ochs, D, Kaletta, C, Entian, K D, Beck-Sickinger, A, Poralla, K
The pentacyclic hopanoids, a class of eubacterial lipids, are synthesized by squalene-hopene cyclase and side chain-elongating enzymes. With the aid of DNA probes based on the amino-terminal sequence...
Saccharomyces cerevisiae regulatory genes CAT1 and CAT3 constitute a positive control circuit necessary for derepression of gluconeogenic and disaccharide-utilizing enzymes. Mutations within these...
Nisin produced by Streptococcus lactis is used as a food preservative and is the most important member of a group of antibiotics containing lanthionine bridges. To understand the genetic basis of...
A selection system has been devised for isolating hexokinase PII structural gene mutants that cause defects in carbon catabolite repression, but retain normal catalytic activity. We used diploid...
A mutation causing resistance to carbon catabolite repression in gene HEX2, mutant allele hex2-3, causes an extreme sensitivity to maltose when in combination with the genes necessary for maltose...
Hedges, D, Proft, M, Entian, K D
The expression of gluconeogenic fructose-1,6-bisphosphatase (encoded by the FBP1 gene) depends on the carbon source. Analysis of the FBP1 promoter revealed two upstream activating elements, UAS1FBP1...
Randez-Gil, F, Bojunga, N, Proft, M, Entian, K D
The Cat8p zinc cluster protein is essential for growth of Saccharomyces cerevisiae with nonfermentable carbon sources. Expression of the CAT8 gene is subject to glucose repression mainly caused by...
Entian, K D, Hilberg, F, Opitz, H, Mecke, D
The regulatory hexokinase PII mutants isolated previously (K.-D. Entian and K.-U. Fröhlich, J. Bacteriol. 158:29-35, 1984) were characterized further. These mutants were defective in glucose...
CAT5, a new gene necessary for derepression of gluconeogenic enzymes in Saccharomyces cerevisiae.
Proft, M, Kötter, P, Hedges, D, Bojunga, N, Entian, K D
PCK1 encoding phosphoenolpyruvate carboxykinase is transcriptionally regulated by two upstream activating elements. By screening for mutants that failed to derepress a UAS2PCK1-CYC1-lacZ reporter...
Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X.
Galibert, F, Alexandraki, D, Baur, A, Boles, E, Chalwatzis, N, Chuat, J C, ...
The complete nucleotide sequence of Saccharomyces cerevisiae chromosome X (745 442 bp) reveals a total of 379 open reading frames (ORFs), the coding region covering approximately 75% of the entire...