Pauwels, R, Andries, K, Debyser, Z, Van Daele, P, Schols, D, Stoffels, P, ...
In vitro evaluation of a large chemical library of pharmacologically acceptable prototype compounds in a high-capacity, cellular-based screening system has led to the discovery of another family of...
Ojwang, J O, Buckheit, R W, Pommier, Y, Mazumder, A, De Vreese, K, Esté, J A, ...
T30177, an oligonucleotide composed of only deoxyguanosine and thymidine, is 17 nucleotides in length and contains single phosphorothioate internucleoside linkages at its 5' and 3' ends for...
De Vreese, K, Van Nerum, I, Vermeire, K, Anné, J, De Clercq, E
The bicyclams are a new class of anti-human immunodeficiency virus (anti-HIV) compounds targeted at viral entry. From marker rescue experiments, it appears that the envelope gp120 glycoprotein plays...
The molecular target of bicyclams, potent inhibitors of human immunodeficiency virus replication.
De Vreese, K, Kofler-Mongold, V, Leutgeb, C, Weber, V, Vermeire, K, Schacht, S, ...
Bicyclams are a novel class of antiviral compounds which act as potent and selective inhibitors of the replication of human immunodeficiency virus type 1 (HIV-1) and HIV-2. They block an early step...
De Clercq, E, Yamamoto, N, Pauwels, R, Balzarini, J, Witvrouw, M, De Vreese, K, ...
Bicyclams, in which the cyclam (1,4,8,11-tetraazacyclotetradecane) moieties are tethered via an aliphatic bridge (i.e., propylene, as in JM2763) are potent and selective inhibitors of human...
Pauwels, R, Andries, K, Debyser, Z, Van Daele, P, Schols, D, Stoffels, P, ...
In vitro evaluation of a large chemical library of pharmacologically acceptable prototype compounds in a high-capacity, cellular-based screening system has led to the discovery of another family of...
Ojwang, J O, Buckheit, R W, Pommier, Y, Mazumder, A, De Vreese, K, Esté, J A, ...
T30177, an oligonucleotide composed of only deoxyguanosine and thymidine, is 17 nucleotides in length and contains single phosphorothioate internucleoside linkages at its 5' and 3' ends for...
De Vreese, K, Van Nerum, I, Vermeire, K, Anné, J, De Clercq, E
The bicyclams are a new class of anti-human immunodeficiency virus (anti-HIV) compounds targeted at viral entry. From marker rescue experiments, it appears that the envelope gp120 glycoprotein plays...
The molecular target of bicyclams, potent inhibitors of human immunodeficiency virus replication.
De Vreese, K, Kofler-Mongold, V, Leutgeb, C, Weber, V, Vermeire, K, Schacht, S, ...
Bicyclams are a novel class of antiviral compounds which act as potent and selective inhibitors of the replication of human immunodeficiency virus type 1 (HIV-1) and HIV-2. They block an early step...
De Clercq, E, Yamamoto, N, Pauwels, R, Balzarini, J, Witvrouw, M, De Vreese, K, ...
Bicyclams, in which the cyclam (1,4,8,11-tetraazacyclotetradecane) moieties are tethered via an aliphatic bridge (i.e., propylene, as in JM2763) are potent and selective inhibitors of human...