K. Farid Ahmad

Crystal structure of the BTB domain from PLZF

Ahmad, K. Farid, Engel, Christian K., Privé, Gilbert G.

The BTB domain (also known as the POZ domain) is an evolutionarily conserved protein–protein interaction motif found at the N terminus of 5–10% of C2H2-type zinc-finger transcription factors, as...

In-Depth Mutational Analysis of the Promyelocytic Leukemia Zinc Finger BTB/POZ Domain Reveals Motifs and Residues Required for Biological and Transcriptional Functions

Melnick, Ari, Ahmad, K. Farid, Arai, Sally, Polinger, Adam, Ball, Helen, Borden, Katherine L., ...

The promyelocytic leukemia zinc finger (PLZF) protein is a transcription factor disrupted in patients with t(11;17)(q23;q21)-associated acute promyelocytic leukemia. PLZF contains an N-terminal...

Critical Residues within the BTB Domain of PLZF and Bcl-6 Modulate Interaction with Corepressors

Melnick, Ari, Carlile, Graeme, Ahmad, K. Farid, Kiang, Chih-Li, Corcoran, Connie, Bardwell, Vivian, ...

The PLZF (promyelocytic leukemia zinc finger) transcriptional repressor, when fused to retinoic acid receptor alpha (RARα), causes a refractory form of acute promyelocytic leukemia. The highly...

Crystal structure of the BTB domain from PLZF

Ahmad, K. Farid, Engel, Christian K., Privé, Gilbert G.

The BTB domain (also known as the POZ domain) is an evolutionarily conserved protein–protein interaction motif found at the N terminus of 5–10% of C2H2-type zinc-finger transcription factors, as...

In-Depth Mutational Analysis of the Promyelocytic Leukemia Zinc Finger BTB/POZ Domain Reveals Motifs and Residues Required for Biological and Transcriptional Functions

Melnick, Ari, Ahmad, K. Farid, Arai, Sally, Polinger, Adam, Ball, Helen, Borden, Katherine L., ...

The promyelocytic leukemia zinc finger (PLZF) protein is a transcription factor disrupted in patients with t(11;17)(q23;q21)-associated acute promyelocytic leukemia. PLZF contains an N-terminal...

Critical Residues within the BTB Domain of PLZF and Bcl-6 Modulate Interaction with Corepressors

Melnick, Ari, Carlile, Graeme, Ahmad, K. Farid, Kiang, Chih-Li, Corcoran, Connie, Bardwell, Vivian, ...

The PLZF (promyelocytic leukemia zinc finger) transcriptional repressor, when fused to retinoic acid receptor alpha (RARα), causes a refractory form of acute promyelocytic leukemia. The highly...