K. Hayashi

ABC and MFS transporters from Botrytis cinerea involved in sensitivity to fungicides and natural toxic compounds (2003)

Modulators known to reduce multidrug resistance in tumour cells were tested for their potency to synergize the fungitoxic activity of the fungicide oxpoconazole, a sterol demethylation inhibitor...

Total AC loss in twisted and untwisted multifilamentary Bi-2223 superconducting tapes carrying AC transport current in AC longitudinal magnetic field (2003)

http://library.wur.nl/wda/abstracts/ab3459.html

Amemiya, N., Jin, F., Jiang, Z., Shirai, S., Haken, B. Ten, Rabbers, J.J., ...

Geometrical, functional, and histomorphometric adaptation of rat carotid artery in induced hypertension (2003)

Fridez, P, Zulliger, M, Bobard, F, Montoriz, G, Miyazaki, H, Hayashi, K, ...

R&D of diamond films in the Frontier Carbon Technology Project and related topics (2003)

Kobashi, K, Nishibayashi, Y, Yokota, Y, Ando, Y, Tachibana, T, Kawakami, N, ...

Fibrous structures on diamond and carbon surfaces formed by hydrogen plasma under direct current bias and field electron-emission properties (2003)

Kobashi, K, Tachibana, T, Yokota, Y, Kawakami, N, Hayashi, K, Yamamoto, K, ...

Fatigue-damage evolution and damage-induced reduction of critical current of a Nb3Al superconducting composite (2003)

Ochiai, S, Sekino, F, Sawada, T, Ohno, H, Hojo, M, Tanaka, M, ...

Vortex-excited vibration of a circular cylinder in planar oscillating flow (2003)

Hayashi, K., Higaki, F., Shigemura, T., Chaplin, J.R.

Laboratory investigation has been made for a comprehensive study of the dynamic transverse response of a circular cylinder in planar oscillating flow. The test cylinder, 0.03 m in diameter and 0.48 m...

Dynamics of Gray Matter Loss in Alzheimer's Disease (2003)

Thompson, P., Hayashi, K., DeZubicaray, G. I, Janke, A. L., Rose, S. E., Semple, J., ...

We detected and mapped a dynamically spreading wave of gray matter loss in the brains of patients with Alzheimer's disease (AD). The loss pattern was visualized in four dimensions as it spread over...

How did the solar wind structure change around the solar maximum? From interplanetary scintillation observation (2003)

Fujiki, K., Kojima, M., Tokumaru, M., Ohmi, T., Yokobe, A., Hayashi, K., ...

Observations from the second Ulysses fast latitude scan show that the global structure of solar wind near solar maximum is much more complex than at solar minimum. Soon after solar maximum, Ulysses...

How did the solar wind structure change around the solar maximum? From interplanetary scintillation observation (2003)

Fujiki, K., Kojima, M., Tokumaru, M., Ohmi, T., Yokobe, A., Hayashi, K., ...

Observations from the second Ulysses fast latitude scan show that the global structure of solar wind near solar maximum is much more complex than at solar minimum. Soon after solar maximum, Ulysses...

Oxatomide for stable asthma in adults and children (2003)

Hayashi, K, Yanagi, M, Wood-Baker, R, Takmatsu, I, Anami, K

Vibrio superstes sp nov., isolated from the gut of Australian abalones Haliotis laevigata and Haliotis rubra (2003)

HAYASHI, K, MORIWAKI, J, SAWABE, T, THOMPSON, FL, Swings, Jean, GUDKOVS, N, ...

Dynamics of Gray Matter Loss in Alzheimer's Disease (2003)

Thompson, P., Hayashi, K., DeZubicaray, G. I, Janke, A. L., Rose, S. E., Semple, J., ...

We detected and mapped a dynamically spreading wave of gray matter loss in the brains of patients with Alzheimer's disease (AD). The loss pattern was visualized in four dimensions as it spread over...

A novel polymorphism of the human APRIL gene is associated with systemic lupus erythematosus (2003)

Koyama, T., Tsukamoto, H., Masumoto, K., Himeji, D., Hayashi, K., Harada, M., ...

Objective. We investigated the association of gene polymorphisms in APRIL, a new member of the TNF family, with systemic lupus erythematosus. Methods. To detect polymorphisms of the human APRIL gene...

A novel polymorphism of the human APRIL gene is associated with systemic lupus erythematosus (2003)

Koyama, T., Tsukamoto, H., Masumoto, K., Himeji, D., Hayashi, K., Harada, M., ...

Objective. We investigated the association of gene polymorphisms in APRIL, a new member of the TNF family, with systemic lupus erythematosus. Methods. To detect polymorphisms of the human APRIL gene...

A novel polymorphism of the human APRIL gene is associated with systemic lupus erythematosus (2003)

Koyama, T., Tsukamoto, H., Masumoto, K., Himeji, D., Hayashi, K., Harada, M., ...

Objective. We investigated the association of gene polymorphisms in APRIL, a new member of the TNF family, with systemic lupus erythematosus. Methods. To detect polymorphisms of the human APRIL gene...

RK/100 and RK/200 Quantum Hall Array Resistance Standards (2002)

Poirier, W., Bounouh, A., Hayashi, K., Fhima, H., Piquemal, F., Geneves, G., ...

It is theoretically possible to combine several Hall bars in arrays to define new quantum standards with perfectly quantized resistance values. We have thus, for the first time, developed and...

Bcmfs1, a novel major facilitator superfamily transporter from Botrytis cinerea, provides tolerance towards the natural toxic compounds camptothecin and cercosporin and towards fungicides (2002)

Expression of the ABC transporter BcatrD from Botrytis cinerea reduces sensitivity to sterol demethylation inhibitor fungicides (2002)

Bcmfs1, a novel major facilitator superfamily gene from Botrytis cinerea, was cloned, and replacement and overexpression mutants were constructed to study its function. Replacement mutants showed...

Effect of body iron stores on indices of biosynthesis and destruction of red blood cells after a single session of cycling exercise (2002)

The ATP-binding cassette (ABC) transporter gene BcatrD from Botrytis cinerea was cloned and characterized. The open reading frame of BcatrD contains seven introns and encodes a putative protein of...

Kawano, Y, Tokashiki, A, Mekata, Y, Hayashi, K, Matsumoto, H, Uchiyama, I

Longitudinal magnetization loss in twisted multifilamentary Bi2223 tape (2002)

Amemiya, N., Krooshoop, H.J.G. (B.E.), Haken Ten, B., Ayai, N., ...

Multifilamentary Bi2223 tapes are exposed to the longitudinal magnetic field as well as the transverse one in some electrical power apparatuses such as multilayer power transmission cables. Here, we...

Fluorescent amplified fragment length polymorphism and repetitive extragenic palindrome-PCR fingerprinting reveal host-specific genetic diversity of Vibrio halioticoli-like strains isolated from the gut of Japanese abalone. (2002)

SAWABE, T, THOMPSON, FL, Heyrman, Jeroen, CNOCKAERT, M, HAYASHI, K, TANAKA, R, ...

Fluorescent amplified fragment length polymorphism and repetitive extragenic palindrome-PCR fingerprinting reveal host-specific genetic diversity of Vibrio halioticoli-like strains isolated from the gut of Japanese abalone (2002)

Thompson, FL, Cnockaert, M, Hayashi, K, Tanaka, R, ...

When analyzed by fluorescent amplified fragment length polymorphism and repetitive extragenic palindrome-PCR fingerprinting, a total of 47 Vibrio halioticoli strains isolated from four Japanese...

Investigation of insulin clearance in septic patients with glucose intolerance: analysis under strict blood glucose control by means of artificial pancreas (2001)

Hoshino, M, Haraguchi, Y, Sakai, M, Hayashi, K, Miyayama, N, Saegusa, H, ...

No abstract available.

Local-structure analysis around dopant atoms using multiple energy x-ray holography (2001)

Hayashi, K, Matsui, M, Awakura, Y, Kaneyoshi, T, Tanida, H, Ishii, M

Multidrug resistance in Botrytis cinerea associated with decreased accumulation of the azole fungicide oxpoconazole and increased transcription of the ABC transporter gene BcatrD (2001)

Hayashi, K., Schoonbeek, H., Sugiura, H.

Azole-resistant mutants of Botrytis cinerea have a multidrug resistance phenotype since they exhibit cross-resistance to unrelated chemicals. These mutants also display resistance to the new azole...

ATP-binding cassette (ABC) transporters from Botrytis cinerea (2001)

Hayashi, K., Schoonbeek, H., Vermeulen, T.

Broadband transverse waves below 1 Hz in the afternoon sector of the magnetosphere (2001)

Matsui, H, Hayashi, K, Mukai, T, Ohtani, S, Kokubun, S, Yamamoto, T, ...

Local-structure analysis around dopant atoms using multiple energy x-ray holography (2001)

Hayashi, K, Matsui, M, Awakura, Y, Kaneyoshi, T, Tanida, H, Ishii, M

Development of apparatus for multiple energy X-ray holography at SPring-8 (2001)

Hayashi, K, Miyake, M, Tobioka, T, Awakura, Y, Suzuki, M, Hayakawa, S

Rim structure formation of isothermally irradiated UO2 fuel discs (2001)

Une, K., Nogita, K., Shiratori, T., Hayashi, K.

Thermal conductivities of irradiated UO2 and (U,Gd)02 (2001)

Minato, K, Shiratori, T., Serizawa, H, Hayashi, K., Une, K., Nogita, K., ...

Rim structure formation of isothermally irradiated UO2 fuel discs (2001)

Une, K, Nogita, K, Shiratori, T, Hayashi, K

UO2 fuel discs, which had been irradiated at an isothermal condition of 550-630 degreesC to 51, 86 and 90 GWd/t without any restraint pressure, have been subjected to detailed microstructure...

Thermal conductivities of irradiated UO2 and (U,Gd)O-2 (2001)

Minato, K, Shiratori, T, Serizawa, H, Hayashi, K, Une, K, Nogita, K, ...

The evaluation of thermal conductivity of irradiated fuel is very important since it directly affects the fuel operating temperature. The disk-shaped UO2 and UO2-10 wt%Gd2O3 samples were prepared and...

Rim structure formation of isothermally irradiated UO2 fuel discs (2001)

Une, K., Nogita, K., Shiratori, T., Hayashi, K.

Thermal conductivities of irradiated UO2 and (U,Gd)02 (2001)

Minato, K, Shiratori, T., Serizawa, H, Hayashi, K., Une, K., Nogita, K., ...

Rim structure formation of isothermally irradiated UO2 fuel discs (2001)

Une, K, Nogita, K, Shiratori, T, Hayashi, K

UO2 fuel discs, which had been irradiated at an isothermal condition of 550-630 degreesC to 51, 86 and 90 GWd/t without any restraint pressure, have been subjected to detailed microstructure...

Thermal conductivities of irradiated UO2 and (U,Gd)O-2 (2001)

Minato, K, Shiratori, T, Serizawa, H, Hayashi, K, Une, K, Nogita, K, ...

The evaluation of thermal conductivity of irradiated fuel is very important since it directly affects the fuel operating temperature. The disk-shaped UO2 and UO2-10 wt%Gd2O3 samples were prepared and...

Analysis of the Karlsruhe neutron transmission experiment using MCNP with various beryllium nuclear data. (2001)

Tayama, R., Tsukiyama, T., Hayashi, K., Möllendorff, U.von, Fischer, U., Giese, H., ...

Fusion Engineering and Design, 55(2001) S.365-72

Hypercoagulability indicated by elevated blood TFPI (tissue factor pathway inhibitor) levels is closely related to severity of septic patients with glucose intolerance (2000)

Hoshino, M, Haraguchi, Y, Sakai, M, Hayashi, K, Horita, N, Miyayama, N, ...

No abstract available.

Estimation of emission field and emission site of boron-doped diamond thin-film field emitters (2000)

Gotoh, Y, Kondo, T, Nagao, M, Tsuji, H, Ishikawa, J, Hayashi, K, ...

Shape evolution of electrodeposited bumps into deep cavities (2000)

Hayashi, K, Fukui, Keisuke, Tanaka, Zenzo, Kondo, Kazuo

Metal posts and finer pitch solder bumps are the indispensable microconnectors for chip size packaging and are formed by electrodeposition into deep cavities. It is difficult to stir inside these...

ABC and MFS transporters from Botrytis cinerea (2000)

Del Sorbo, G., Hayashi, K., Schoonbeek, H., Vermeulen, T.

Role of ABC and MFS transporters in resistance of Botrytis cinerea to azole fungicides (2000)

ABC transporters involved insensitivity and resistance of Botrytis cinerea to azole fungicides and other botryticides (2000)

ABC transporters involved insensitivity and resistance of Botrytis cinerea to azole fungicides and other botryticides (2000)

ABC transporters involved insensitivity and resistance of Botrytis cinerea to azole fungicides and other botryticides (2000)

ABC transporters involved insensitivity and resistance of Botrytis cinerea to azole fungicides and other botryticides (2000)

Differences and similarities in fatigue behaviour and its influences on critical current and residual strength between Ti-Nb and Nb3Al superconducting composite wires (2000)

Ochiai, S, Oki, Y, Sekino, F, Ohno, H, Hojo, M, Moriai, H, ...

Surface traveling X-rays from organic thin film (2000)

Hayashi, K, Kawai, J

Estimation of emission field and emission site of boron-doped diamond thin-film field emitters (2000)

Gotoh, Y, Kondo, T, Nagao, M, Tsuji, H, Ishikawa, J, Hayashi, K, ...

Data processing for obtaining atomic images from SrTiO3 X-ray fluorescence hologram (2000)

Hayashi, K, Sai, M, Yamamoto, T, Kawai, J, Nishino, M, Hayakawa, S, ...

Differences and similarities in fatigue behaviour and its influences on critical current and residual strength between Ti-Nb and Nb3Al superconducting composite wires (2000)

Ochiai, S, Oki, Y, Sekino, F, Ohno, H, Hojo, M, Moriai, H, ...

Analysis of p53 tumour suppressor gene somatic mutations in rheumatoid arthritis synovium (2000)

Inazuka, M., Tahira, T., Horiuchi, T., Harashima, S., Sawabe, T., Kondo, M., ...

Objective. In order to study the role of the p53 tumour suppressor gene in the proliferation of rheumatoid arthritis (RA) synovium, we analysed the mutation of p53 in the synovial...

Dependence of AC transport current losses of HTS wires on their structures and synthesizing processes (1999)

Tsukamoto, Osami, Miyagi, D., Ishii, S., Amemiya, N., Fukui, S., Kasuu, O., ...

HTS wires of various structures and synthesizing processes are being developed for power apparatus applications in Super-CM project. AC transport current losses of four of those wires were measured...

ABC transporters involved in sensitivity and resistance of Botrytis cinerea to azole fungicides and other botryticides (1999)

Total reflection x-ray photoelectron spectroscopy of a tantalum-titanium multilayer (1999)

Kawai, J, Sai, M, Sugimura, T, Hayashi, K, Takenaka, H, Kitajima, Y

Depth profiles of damage accumulation in UO2 and (U,Gd)O2 pellets irradiated with 100 MeV iodine (1999)

Nogita, K., Hayashi, K., Une, K., Fukuda, K.

To study the initial defect formation and accumulation process during fission events, sliced pellet specimens of UO2 and (U,Gd)O2 were irradiated at ambient temperatures below 200°C, with 100 MeV...

Subtraction ICG angiography in Harada's disease. (1999)

KOHNO, T, MIKI, T, SHIRAKI, K, KANO, K, MATSUSHITA, M, HAYASHI, K, ...

Depth profiles of damage accumulation in UO2 and (U,Gd)O2 pellets irradiated with 100 MeV iodine (1999)

Nogita, K., Hayashi, K., Une, K., Fukuda, K.

To study the initial defect formation and accumulation process during fission events, sliced pellet specimens of UO2 and (U,Gd)O2 were irradiated at ambient temperatures below 200°C, with 100 MeV...

Association of Fas/APO-1 gene polymorphism with systemic lupus erythematosus in Japanese (1999)

Horiuchi, T, Nishizaka, H, Yasunaga, S, Higuchi, M, Tsukamoto, H, Hayashi, K, ...

Lung cancer in patients who had received thoracoplasty for pulmonary tuberculosis (1999)

Tamura, A, Hebisawa, A, Hayashi, K, Sagara, Y, Kawabe, Y, Nagayama, N, ...

Phase Decomposition and Deformation of L12-Ordered Co-Rich Co3Ti. (1998)

Nemoto, M., Tian, W. H., Hayashi, K.

This paper concerned metals in some important way and contained information about, utilized, or discussed these subjects: basic topics: experimental materials and material types: co3ti, li2, ni3al...

Fabrication of Uniform Ceramics-Alloy Composite Powder by Combination of Equalization of Those Densities and Rapid Solidification. (1998)

Asanuma, H., Hirohashi, M., Hayashi, K.

This paper concerned mmc in some important way and contained information about, utilized, or discussed these subjects: basic topics:, data, dr mmc, experimental, mmc, mmc data materials and material...

Room Temperature Strength and Microstructure of Si3N4-Y2O3-ZrO2-Al2O3 Ceramics. (1998)

Hayashi, K., Yamakawa, A.

Si3N4-(0-24) mol% Y2O3-(0-27)mol% ZrO2-(4.0-4.6)mol% Al2O3 compacts were sintered in nitrogen gas at 0.5 MPa and 2073 K for 7.2 ks. The room temperature mechanical properties, and in particular the...

Simultaneous Measurements of Thermal Conductivity, Diffusivity and Specific Heat of Refractories by the Transient Hot Wire Method. (1998)

Hayashi, K., Okamoto, Y., Nishikawa, T.

Close relationship of PAI-1 (plasminogen activator inhibitor-1) with multiple organ dysfunction syndrome and abnormal glucose metabolism investigated by means of artificial pancreas (1998)

Hoshino, M, Haraguchi, Y, Sakai, M, Saegusa, H, Hayashi, K, Horita, N, ...

No abstract available.

c-Myc gene single-strand binding protein-1, MSSP-1, suppresses transcription of alpha-smooth muscle actin gene in chicken visceral smooth muscle cells (1998)

Kimura, K, Saga, H, Hayashi, K, Obata, H, Chimori, Y, Ariga, H, ...

Cosmic strings in the Schwarzchild space-time and ultra high energy cosmic rays (1997)

Hayashi, K, Nakamura, S, Shinoda, T

The mechanism of catecholaminergic polymorphic ventricular tachycardia may be triggered activity due to delayed afterdepolarization (1997)

NAKAJIMA, T., KANEKO, Y., TANIGUCHI, Y., HAYASHI, K., TAKIZAWA, T., SUZUKI, T., ...

Antiviral activity of 5,6,7-trimethoxyflavone and its potentiation of the antiherpes activity of acyclovir (1997)

Hayashi, K, Hayashi, T, Otsuka, H, Takeda, Y

Anaplastic Ki-1-positive large cell lymphoma of the pancreas: a case report and review of the literature (1997)

Maruyama, H, Nakatsuji, N, Sugihara, S, Atsumi, M, Shimamoto, K, Hayashi, K, ...

Aerogel Cerenkov counter for the BELLE experiment (1996)

Iijima, T, Adachi, I, Amami, M, Enomoto, R, Guo, R S, Hayashi, K, ...

Energy of General Spherically Symmetric Solution in Tetrad Theory of Gravitation (1996)

Shirafuji, T., Nashed, G. G. L., Hayashi, K.

We find the most general, spherically symmetric solution in a special class of tetrad theory of gravitation. The tetrad gives the Schwarzschild metric. The energy is calculated by the superpotential...

One-tube post-PCR fluorescent labeling of DNA fragments (1996)

Inazuka, M, Tahira, T, Hayashi, K

Performance of VENUS lead glass counters in pion and electron beams and in an upgraded VENUS detector (1995)

Ogawa, K, Sakuda, M, Hayashi, K, Kohriki, T, Sumiyoshi, T, Watase, Y, ...

RNA-primed PCR (1995)

Shibata, H, Tahira, T, Hayashi, K

Test of Japanese evaluated beryllium nuclear data against the Karlsruhe neutron transmission experiment. (1995)

Hayashi, K., Möllendorff, U.von, Tsukiyama, T., Kappler, F., Tayama, R., Giese, H.

Herschbach, K. [Hrsg.]

Test of various evaluated beryllium nuclear data against the Karlsruhe neutron transmission experiment. (1995)

Tayama, R., Tsukiyama, T., Hayashi, K., Giese, H., Kappler, F., Möllendorff, U.von

1995 Spring Meeting of the Atomic Energy Society of Japan, Tokyo, March 28-30, 1995

Induction chemoradiotherapy followed by surgery for stage III non-small cell lung cancer (1993)

Yoneda, S, Yamamoto, M, Sakura, M, Izumo, T, Noguchi, Y, Nishimura, H, ...

Dinucleotide repeat polymorphism at the D19S386 locus (1993)

Iizuka, M, Teshima, H, Sekiya, T, Hayashi, K

F-SSCP: fluorescence-based polymerase chain reaction-single-strand conformation polymorphism (PCR-SSCP) analysis (1992)

Makino, R, Yazyu, H, Kishimoto, Y, Sekiya, T, Hayashi, K

Single-strand conformation polymorphism (SSCP) at the D8S86 locus (1992)

Lizuka, M., Hayashi, K., Sekiya, T.

Nucleic Acids Research, 19, p. 6346 (1991) The publishers wish to apologize for the inadvertant inclusion of the word (figure) in the text of this article.

Measurement of neutron transport and multiplication in beryllium. (1992)

Ebi, H., Eyrich, W., Fries, H., Giese, H., Hayashi, K., Kappler, F., ...

Proc.of the 2nd Internat.Symp.on Fusion Nuclear Technology, Karlsruhe, June 2-7, 1991 Part C

Single-strand conformation polymorphism (SSCP) at the D8S86 locus (1991)

Iizuka, M., Hayashi, K., Sekiya, T.

Single-strand conformation polymorphism (SSCP) at the D8S86 locus [published erratum appears in Nucleic Acids Res 1992 Jan 25;20(2):388] (1991)

Iizuka, M, Hayashi, K, Sekiya, T

Three RFLPs at the D8S586 locus (1991)

Iizuka, M., Shiraishi, M., Hayashi, K., Sekiya, T.

Three RFLPs at the D8S586 locus (1991)

Iizuka, M, Shiraishi, M, Hayashi, K, Sekiya, T

RAMAN STUDY OF La2-xBaxCuO4 (x= 0, 0.016) SINGLE CRYSTALS (1988)

Koshizuka, N., Unoki, H., Oka, K., Hayashi, K., Okuda, T., Kimura, Y.

Raman scattering of La2-xBaxCuO4 (x = 0, 0.016) single crystals has been measured at various temperatures in the frequency range between 100 and 5000 cm-1. Besides an A1g phonon line at 430 cm-1, the...

RAMAN STUDY OF La2-xBaxCuO4 (x= 0, 0.016) SINGLE CRYSTALS (1988)

Koshizuka, N., Unoki, H., Oka, K., Hayashi, K., Okuda, T., Kimura, Y.

Raman scattering of La2-xBaxCuO4 (x = 0, 0.016) single crystals has been measured at various temperatures in the frequency range between 100 and 5000 cm-1. Besides an A1g phonon line at 430 cm-1, the...

RAMAN STUDY OF La2-xBaxCuO4 (x= 0, 0.016) SINGLE CRYSTALS (1988)

Koshizuka, N., Unoki, H., Oka, K., Hayashi, K., Okuda, T., Kimura, Y.

Raman scattering of La2-xBaxCuO4 (x = 0, 0.016) single crystals has been measured at various temperatures in the frequency range between 100 and 5000 cm-1. Besides an A1g phonon line at 430 cm-1, the...

Effect of Anoxia on the Spatial Pattern of Electric Potential Formed Along the Root (1988)

YOSHIDA, T., HAYASHI, K., TOKO, K., YAMAFUJI, K.

Spatial patterns of surface electric potential of a root of azuki bean (Phaseolus chrysanthos) were investigated. A multi-electrode measuring system was used to measure the spatial pattern and its...

Malignant fibrous histiocytoma at site of bone infarction in association with DCS (1984)

M. Kitano, H. Iwasaki, S. S. Yoh, K. Kuroda, K. Hayashi

Undersea and Hyperbaric Medical Society, Inc. (http://www.uhms.org )

Histopathology of the early stage of osteonecrosis in divers (1977)

M. Kawashima, K. Hayashi, T. Torisu, M. Kitano

Undersea and Hyperbaric Medical Society, Inc. (http://www.uhms.org )

Mutant oocytic low density lipoprotein receptor gene family member causes atherosclerosis and female sterility.

Bujo, H, Yamamoto, T, Hayashi, K, Hermann, M, Nimpf, J, Schneider, W J

The so-called very low density lipoprotein receptors (VLDLRs) are related to the LDLR gene family. So far, naturally occurring mutations have only been described for the prototype LDLR; in humans,...

Genomic structure of the human caldesmon gene.

Hayashi, K, Yano, H, Hashida, T, Takeuchi, R, Takeda, O, Asada, K, ...

The high molecular weight caldesmon (h-CaD) is predominantly expressed in smooth muscles, whereas the low molecular weight caldesmon (l-CaD) is widely distributed in nonmuscle tissues and cells. The...

c-Myc gene single-strand binding protein-1, MSSP-1, suppresses transcription of alpha-smooth muscle actin gene in chicken visceral smooth muscle cells.

Kimura, K, Saga, H, Hayashi, K, Obata, H, Chimori, Y, Ariga, H, ...

The expression of alpha-smooth muscle actin is coordinately regulated by positive and negative cis- elements in the promoter region. Although cis -elements and trans -acting factors involved in the...

Application of ozone disinfection to remove Enterococcus seriolicida, Pasteurella piscicida, and Vibrio anguillarum from seawater.

Sugita, H, Asai, T, Hayashi, K, Mitsuya, T, Amanuma, K, Maruyama, C, ...

Survival of bacterial fish pathogens, including Enterococcus seriolicida, Vibrio anguillarum, and Pasteurella piscicida, in ozonated seawater was determined in a batch system. Bacterial counts of all...

Mechanism of action of the antiherpesvirus biflavone ginkgetin.

Hayashi, K, Hayashi, T, Morita, N

Screening of plant extracts found that a biflavone from Cephalotaxus drupacea, which was found to be ginkgetin, is active against herpes simplex virus type 1 (HSV-1). This compound caused...

Bacillus subtilis alkA gene encoding inducible 3-methyladenine DNA glycosylase is adjacent to the ada operon.

Morohoshi, F, Hayashi, K, Munkata, N

In Bacillus subtilis, the adaptive response to DNA alkylation depends on the ada operon, which consists of the adaA and adaB genes, which encode methylphosphotriester DNA methyltransferase (AdaA...

Molecular analysis of Bacillus subtilis ada mutants deficient in the adaptive response to simple alkylating agents.

Human herpesviruses 6 and 7 in cervixes of pregnant women.

Previously, we isolated and characterized six Bacillus subtilis ada mutants that were hypersensitive to methylnitroso compounds and deficient in the adaptive response to alkylation. Cloning of the...

Okuno, T, Oishi, H, Hayashi, K, Nonogaki, M, Tanaka, K, Yamanishi, K

We looked for human herpesvirus 6 (HHV-6) and HHV-7 genomes in the cervixes of pregnant women in the late stages of their pregnancies. Of 72 samples collected with cervical swabs and amplified by...

Antibody-mediated growth of influenza A NWS virus in macrophagelike cell line P388D1.

Ochiai, H, Kurokawa, M, Hayashi, K, Niwayama, S

We investigated the internalization and growth of influenza A NWS virus in macrophagelike P388D1 cells. Flow cytometric analysis using fluorescein isothiocyanate-labeled virus showed that the...

Herpes simplex virus type 1-induced hydrocephalus in mice.

Hayashi, K, Iwasaki, Y, Yanagi, K

Adult ICR/Slc or BALB/c mice developed hydrocephalus when attenuated herpes simplex virus type 1 (HSV-1) (strain Ska) was injected intracerebrally 2 to 4 weeks earlier and then after mice were...

Chemiluminescent response of polymorphonuclear leukocytes to Streptococcus pneumoniae and Haemophilus influenzae in suspension and adhered to glass.

Hayashi, K, Lee, D A, Quie, P G

We measured the luminol- and lucigenin-enhanced chemiluminescent response of human polymorphonuclear leukocytes (PMN) stimulated by various strains of Streptococcus pneumoniae and Haemophilus...

Development of an enzyme-labeled oligonucleotide probe for the cholera toxin gene.

Yoh, M, Miyagi, K, Matsumoto, Y, Hayashi, K, Takarada, Y, Yamamoto, K, ...

An alkaline phosphatase-conjugated 30-mer oligonucleotide probe was developed to detect the cholera toxin gene (ctx) in Vibrio cholerae O1. For rapid identification, V. cholerae O1 was grown on...

Detection of polymorphisms of human DNA by gel electrophoresis as single-strand conformation polymorphisms.

Orita, M, Iwahana, H, Kanazawa, H, Hayashi, K, Sekiya, T

We developed mobility shift analysis of single-stranded DNAs on neutral polyacrylamide gel electrophoresis to detect DNA polymorphisms. This method follows digestion of genomic DNA with restriction...

Activation of human c-raf-1 by replacing the N-terminal region with different sequences.

Tahira, T, Ochiai, M, Hayashi, K, Nagao, M, Sugimura, T

Two transformants of NIH 3T3 cells, obtained by the transfection of human colon cancer and normal colon DNAs, contained activated c-raf-1. In both the activated c-raf-1, the 5' half of the c-raf-1...

Characterization of rat c-myc and adjacent regions.

Hayashi, K, Makino, R, Kawamura, H, Arisawa, A, Yoneda, K

Rat genomic regions covering c-myc were cloned from the DNA of both normal liver and two lines of Morris hepatomas, one of which had c-myc amplification. The three restriction maps showed perfect...

Cloning and characterization of a c-myc intron binding protein (MIBP1).

Makino, R, Akiyama, K, Yasuda, J, Mashiyama, S, Honda, S, Sekiya, T, ...

The cDNA for a c-myc intron 1 binding protein 1 (MIBP1) in the rat was isolated from lambda gt11 and lambda ZAPII cDNA libraries. Sequencing of the cDNA clones revealed a long ORF which encoded a...

Regulation of inter- and intramolecular ligation with T4 DNA ligase in the presence of polyethylene glycol.

Hayashi, K, Nakazawa, M, Ishizaki, Y, Hiraoka, N, Obayashi, A

Polyethylene glycol (PEG) stimulates ligation with T4 DNA ligase. In 10% (w/v) PEG 6,000 solutions, only intermolecular ligation is enhanced by monovalent cations, while both inter- and...

Purification and partial characterization of a type-specific antigen of Rickettsia tsutsugamushi.

Ohashi, N, Tamura, A, Ohta, M, Hayashi, K

A type-specific antigen (54- to 56-kilodalton polypeptide) in the envelope of Rickettsia tsutsugamushi was purified from each of three prototype strains (Gilliam, Karp, and Kato) by a combination of...

Use of labeled primers in polymerase chain reaction (LP-PCR) for a rapid detection of the product.

Hayashi, K, Orita, M, Suzuki, Y, Sekiya, T

Bacillus subtilis gene coding for constitutive O6-methylguanine-DNA alkyltransferase.

Stimulation of intermolecular ligation with E. coli DNA ligase by high concentrations of monovalent cations in polyethylene glycol solutions.

We have cloned a Bacillus subtilis DNA fragment that could correct the defect in a constitutive O6-methylguanine-DNA alkyltransferase (Dat1). This fragment also corrected the hypersensitivity of the...

Hayashi, K, Nakazawa, M, Ishizaki, Y, Hiraoka, N, Obayashi, A

In the presence of high concentrations of the nonspecific polymer polyethylene glycol (PEG), intermolecular cohesive-end ligation with the DNA ligase from Escherichia coli was stimulated by high salt...

Activation of rat c-raf during transfection of hepatocellular carcinoma DNA.

Ishikawa, F, Takaku, F, Hayashi, K, Nagao, M, Sugimura, T

Rat c-raf was found to be activated in a transformant obtained with DNA of a hepatocellular carcinoma induced by 2-amino-3-methylimidazo[4,5-f]quinoline. This activated c-raf was cloned in a cosmid...

Organization of sequences related to U6 RNA in the human genome.

Hayashi, K

Small nuclear RNAs were isolated from human placenta and fractionated into individual molecular species. They were then iodinated with 125I and used as probes to screen the human genome. Of 2 x 10(4)...

Single-strand conformation polymorphism (SSCP) at the D8S86 locus

Iizuka, M., Hayashi, K., Sekiya, T.

Bacillus subtilis ada operon encodes two DNA alkyltransferases.

Three RFLPs at the D8S586 locus

By prophage transformation and subcloning, we have obtained Bacillus subtilis DNA fragments that could complement the hypersensitivity of ada (adaptive response deficient) mutants to...

Iizuka, M., Shiraishi, M., Hayashi, K., Sekiya, T.

Gonadal luteinizing hormone receptors and adenylate cyclase: transfer of functional ovarian luteinizing hormone receptors to adrenal fasciculata cells.

Dufau, M L, Hayashi, K, Sala, G, Baukal, A, Catt, K J

Luteinized rat ovaries contain a high concentration of particulate luteinizing hormone (lutropin, LH) receptors and a small quantity of lipid-associated receptors that float in the 360,000 X g...

Influence of monovalent cations on the activity of T4 DNA ligase in the presence of polyethylene glycol.

Hayashi, K, Nakazawa, M, Ishizaki, Y, Obayashi, A

Monovalent cations such as Na+ and K+ inhibit the activity of T4 DNA ligase. However, the extent of inhibition varies with the terminal sequence of the duplex DNA used as substrate; in many cases,...

Demonstration of high molecular weight poly (adenosine diphosphate ribose).

Tanaka, M, Hayashi, K, Sakura, H, Miwa, M, Matsushima, T, Sugimura, T

An electrophoretic system was established that resolves poly(adenosine diphosphate ribose), enzymatically synthesized polymer from NAD+, by size difference of one residue on polyacrylamide gel. The...

Interactions of norharman and harman with DNA.

Hayashi, K, Nagao, M, Sugimura, T

The interactions of norharman (9H-pyrido [3,4-b] indole) and harman (1-methyl-9H-pyrido [3,4-b] indole) with DNA were studied. DNA caused remarkable fluorescence quenching and change in the...

Structure of the c-Ki-ras gene in a rat fibrosarcoma induced by 1,8-dinitropyrene.

Tahira, T, Hayashi, K, Ochiai, M, Tsuchida, N, Nagao, M, Sugimura, T

Restriction enzyme maps were made of the region around exons 1 and 2 of activated c-Ki-ras of a fibrosarcoma (1,8-DNP2) induced in a rat by 1,8-dinitropyrene. Nucleotide sequence analysis revealed...

Virus-induced diabetes mellitus. V. Biological differences between the M variant and other strains of encephalomyocarditis virus.

Ross, M E, Onodera, T, Hayashi, K, Notkins, A L

The M variant of encephalomyocarditis virus is very closely related serologically to five other strains of encephalomyocarditis virus. Despite the serological relationship, these five viruses differ...

Viral spread in the presence of neutralizing antibody: mechanisms of persistence in foamy virus infection.

Hooks, J J, Burns, W, Hayashi, K, Geis, S, Notkins, A L

Several viruses were categorized on the basis of their ability to spread from cell to contiguous cell and form plaques in the presence of antiviral antibody. Herpes simplex virus, cytomegalovirus,...

Meningeal exudate cells in vaccinia meningitis of mice: role of local T cells.

Morishima, T, Hayashi, K

Intracerebral inoculation of vaccinia virus into adult DDD mice produced intensive meningitis several days after infection. The inflammatory reaction could be quantitated by counting cells obtained...

Collagen fibrillogenesis: intermediate aggregates and suprafibrillar order.

Trelstad, R L, Hayashi, K, Gross, J

Polymerization of collagen in vitro has been studied with the electron microscope at early time points of fibril assembly. We have found morphologically distinct stages of aggregation, which we...

Cellular mechanisms mediating rat renal microvascular constriction by angiotensin II.

Takenaka, T, Suzuki, H, Fujiwara, K, Kanno, Y, Ohno, Y, Hayashi, K, ...

To assess cellular mechanisms mediating afferent (AA) and efferent arteriolar (EA) constriction by angiotensin II (AngII), experiments were performed using isolated perfused hydronephrotic kidneys....

Analysis of the inhibitory effect of peritoneal macrophages on the spread of herpes simplex virus.

Hayashi, K, Kurata, T, Morishima, T, Nassery, T

Peritoneal macrophages obtained from mice after an intraperitoneal injection of tryptose peptone inhibited the development of herpes simplex virus type 2 plaques in syngeneic mouse embryonic...

Antimicrobial Activity of Murine Lung Cells against Staphylococcus aureus Is Increased In Vitro and In Vivo after Elafin Gene Transfer

McMichael, J. W., Maxwell, A. I., Hayashi, K., Taylor, K., Wallace, W. A., Govan, J. R., ...

Staphylococcus aureus is a pathogen often found in pneumonia and sepsis. In the context of the resistance of this organism to conventional antibiotics, an understanding of the regulation of natural...

Construction and characterization of a chimeric beta-glucosidase.

Singh, A, Hayashi, K, Hoa, T T, Kashiwagi, Y, Tokuyasu, K

The amino acid sequences of beta-glucosidases from Cellvibrio gilvus and Agrobacterium tumefaciens show significant similarity in most of the parts. However, the pH/temperature optima and stabilities...

Purification and characterization of three distinct types of phospholipase A2 inhibitors from the blood plasma of the Chinese mamushi, Agkistrodon blomhoffii siniticus.

Ohkura, N, Okuhara, H, Inoue, S, Ikeda, K, Hayashi, K

Three distinct types of phospholipase A2 (PLA2) inhibitory proteins (PLIalpha, PLIbeta, and PLIgamma) were isolated from the blood plasma of the Chinese mamushi, Agkistrodon blomhoffii siniticus....

Intramolecular chaperone and inhibitor activities of a propeptide from a bacterial zinc aminopeptidase.

Nirasawa, S, Nakajima, Y, Zhang, Z Z, Yoshida, M, Hayashi, K

An aminopeptidase from Aeromonas caviae T-64 was translated as a preproprotein consisting of three domains; a signal peptide (19 amino acid residues), an N-terminal propeptide (101 residues) and a...

Purification, characterization and cDNA cloning of a phospholipase A2 inhibitor from the serum of the non-venomous snake Elaphe quadrivirgata.

Okumura, K, Masui, K, Inoue, S, Ikeda, K, Hayashi, K

The serum of a non-venomous striated snake, Elaphe quadrivirgata, was found to contain phospholipase A2 (PLA2) inhibitory proteins (PLIs). One of these inhibitors was purified by Sephadex G-200 gel...

Enhancement of the thermostability and hydrolytic activity of xylanase by random gene shuffling.

Shibuya, H, Kaneko, S, Hayashi, K

The thermostability of Streptomyces lividans xylanase B (SlxB-cat) was significantly increased by the replacement of its N-terminal region with the corresponding region from Thermomonospora fusca...

Function of the N-terminal propeptide of an aminopeptidase from Vibrio proteolyticus.

Zhang, Z Z, Nirasawa, S, Nakajima, Y, Yoshida, M, Hayashi, K

An aminopeptidase from Vibrio proteolyticus was translated as a preproprotein consisting of four domains: a signal peptide, an N-terminal propeptide, a mature region and a C-terminal propeptide....

Thermotropic phase behavior and stability of monosialoganglioside micelles in aqueous solution.

Hirai, M, Takizawa, T, Yabuki, S, Nakata, Y, Hayashi, K

The thermotropic phase behavior of monosialoganglioside in a dilute aqueous dispersion at pH 6.8 was measured by using synchrotron radiation small-angle x-ray scattering and was analyzed by a...

Interaction of gangliosides with proteins depending on oligosaccharide chain and protein surface modification.

Hirai, M, Iwase, H, Arai, S, Takizawa, T, Hayashi, K

By using neutron and synchrotron x-ray small-angle scattering techniques, we investigated the process of the complexation of gangliosides with proteins. We treated monosialoganglioside (G(M1)),...

Genetic mapping of ossification of the posterior longitudinal ligament of the spine.

Koga, H, Sakou, T, Taketomi, E, Hayashi, K, Numasawa, T, Harata, S, ...

Ossification of the posterior longitudinal ligament of the spine (OPLL) is recognized as a common disorder among Japanese and throughout Asia. Estimates of its prevalence are in the range of 1....

Non-enzymic glycation of human extracellular superoxide dismutase.

Adachi, T, Ohta, H, Hirano, K, Hayashi, K, Marklund, S L

The secretory enzyme extracellular superoxide dismutase (EC-SOD) is in plasma heterogenous with regard to heparin-affinity and can be divided into three fractions, A that lacks affinity, B with...

Idiopathic third cranial nerve palsy associated with herpes simplex virus infection.

Sekizawa, T, Nakamura, S, Kogure, K, Hayashi, K, Yanagi, K, Openshaw, H

Isolation of X and Y chromosome-specific DNA markers from a liverwort, Marchantia polymorpha, by representational difference analysis.

Fujisawa, M, Hayashi, K, Nishio, T, Bando, T, Okada, S, Yamato, K T, ...

The liverwort Marchantia polymorpha has X and Y chromosomes in the respective female and male haploids. Here we report the successful exploitation of representational difference analyses to isolate...

The anterior and the posterior longitudinal ligaments of the lower cervical spine.

Hayashi, K, Yabuki, T, Kurokawa, T, Seki, H, Hogaki, M, Minoura, S

The anterior and the posterior longitudinal ligaments (ALL and PLL) of the cervical spine were examined. The ALL and the deep layer of the PLL are continuous, and surround the vertebral body. The...

Mutant oocytic low density lipoprotein receptor gene family member causes atherosclerosis and female sterility.

Bujo, H, Yamamoto, T, Hayashi, K, Hermann, M, Nimpf, J, Schneider, W J

The so-called very low density lipoprotein receptors (VLDLRs) are related to the LDLR gene family. So far, naturally occurring mutations have only been described for the prototype LDLR; in humans,...

Genomic structure of the human caldesmon gene.

Hayashi, K, Yano, H, Hashida, T, Takeuchi, R, Takeda, O, Asada, K, ...

The high molecular weight caldesmon (h-CaD) is predominantly expressed in smooth muscles, whereas the low molecular weight caldesmon (l-CaD) is widely distributed in nonmuscle tissues and cells. The...

c-Myc gene single-strand binding protein-1, MSSP-1, suppresses transcription of alpha-smooth muscle actin gene in chicken visceral smooth muscle cells.

Kimura, K, Saga, H, Hayashi, K, Obata, H, Chimori, Y, Ariga, H, ...

The expression of alpha-smooth muscle actin is coordinately regulated by positive and negative cis- elements in the promoter region. Although cis -elements and trans -acting factors involved in the...

Application of ozone disinfection to remove Enterococcus seriolicida, Pasteurella piscicida, and Vibrio anguillarum from seawater.

Sugita, H, Asai, T, Hayashi, K, Mitsuya, T, Amanuma, K, Maruyama, C, ...

Survival of bacterial fish pathogens, including Enterococcus seriolicida, Vibrio anguillarum, and Pasteurella piscicida, in ozonated seawater was determined in a batch system. Bacterial counts of all...

Mechanism of action of the antiherpesvirus biflavone ginkgetin.

Hayashi, K, Hayashi, T, Morita, N

Screening of plant extracts found that a biflavone from Cephalotaxus drupacea, which was found to be ginkgetin, is active against herpes simplex virus type 1 (HSV-1). This compound caused...

Bacillus subtilis alkA gene encoding inducible 3-methyladenine DNA glycosylase is adjacent to the ada operon.

Morohoshi, F, Hayashi, K, Munkata, N

In Bacillus subtilis, the adaptive response to DNA alkylation depends on the ada operon, which consists of the adaA and adaB genes, which encode methylphosphotriester DNA methyltransferase (AdaA...

Molecular analysis of Bacillus subtilis ada mutants deficient in the adaptive response to simple alkylating agents.

Human herpesviruses 6 and 7 in cervixes of pregnant women.

Previously, we isolated and characterized six Bacillus subtilis ada mutants that were hypersensitive to methylnitroso compounds and deficient in the adaptive response to alkylation. Cloning of the...

Okuno, T, Oishi, H, Hayashi, K, Nonogaki, M, Tanaka, K, Yamanishi, K

We looked for human herpesvirus 6 (HHV-6) and HHV-7 genomes in the cervixes of pregnant women in the late stages of their pregnancies. Of 72 samples collected with cervical swabs and amplified by...

Antibody-mediated growth of influenza A NWS virus in macrophagelike cell line P388D1.

Ochiai, H, Kurokawa, M, Hayashi, K, Niwayama, S

We investigated the internalization and growth of influenza A NWS virus in macrophagelike P388D1 cells. Flow cytometric analysis using fluorescein isothiocyanate-labeled virus showed that the...

Herpes simplex virus type 1-induced hydrocephalus in mice.

Hayashi, K, Iwasaki, Y, Yanagi, K

Adult ICR/Slc or BALB/c mice developed hydrocephalus when attenuated herpes simplex virus type 1 (HSV-1) (strain Ska) was injected intracerebrally 2 to 4 weeks earlier and then after mice were...

Chemiluminescent response of polymorphonuclear leukocytes to Streptococcus pneumoniae and Haemophilus influenzae in suspension and adhered to glass.

Hayashi, K, Lee, D A, Quie, P G

We measured the luminol- and lucigenin-enhanced chemiluminescent response of human polymorphonuclear leukocytes (PMN) stimulated by various strains of Streptococcus pneumoniae and Haemophilus...

Development of an enzyme-labeled oligonucleotide probe for the cholera toxin gene.

Yoh, M, Miyagi, K, Matsumoto, Y, Hayashi, K, Takarada, Y, Yamamoto, K, ...

An alkaline phosphatase-conjugated 30-mer oligonucleotide probe was developed to detect the cholera toxin gene (ctx) in Vibrio cholerae O1. For rapid identification, V. cholerae O1 was grown on...

Detection of polymorphisms of human DNA by gel electrophoresis as single-strand conformation polymorphisms.

Orita, M, Iwahana, H, Kanazawa, H, Hayashi, K, Sekiya, T

We developed mobility shift analysis of single-stranded DNAs on neutral polyacrylamide gel electrophoresis to detect DNA polymorphisms. This method follows digestion of genomic DNA with restriction...

Activation of human c-raf-1 by replacing the N-terminal region with different sequences.

Tahira, T, Ochiai, M, Hayashi, K, Nagao, M, Sugimura, T

Two transformants of NIH 3T3 cells, obtained by the transfection of human colon cancer and normal colon DNAs, contained activated c-raf-1. In both the activated c-raf-1, the 5' half of the c-raf-1...

Characterization of rat c-myc and adjacent regions.

Hayashi, K, Makino, R, Kawamura, H, Arisawa, A, Yoneda, K

Rat genomic regions covering c-myc were cloned from the DNA of both normal liver and two lines of Morris hepatomas, one of which had c-myc amplification. The three restriction maps showed perfect...

Cloning and characterization of a c-myc intron binding protein (MIBP1).

Makino, R, Akiyama, K, Yasuda, J, Mashiyama, S, Honda, S, Sekiya, T, ...

The cDNA for a c-myc intron 1 binding protein 1 (MIBP1) in the rat was isolated from lambda gt11 and lambda ZAPII cDNA libraries. Sequencing of the cDNA clones revealed a long ORF which encoded a...

Regulation of inter- and intramolecular ligation with T4 DNA ligase in the presence of polyethylene glycol.

Hayashi, K, Nakazawa, M, Ishizaki, Y, Hiraoka, N, Obayashi, A

Polyethylene glycol (PEG) stimulates ligation with T4 DNA ligase. In 10% (w/v) PEG 6,000 solutions, only intermolecular ligation is enhanced by monovalent cations, while both inter- and...

Purification and partial characterization of a type-specific antigen of Rickettsia tsutsugamushi.

Ohashi, N, Tamura, A, Ohta, M, Hayashi, K

A type-specific antigen (54- to 56-kilodalton polypeptide) in the envelope of Rickettsia tsutsugamushi was purified from each of three prototype strains (Gilliam, Karp, and Kato) by a combination of...

Use of labeled primers in polymerase chain reaction (LP-PCR) for a rapid detection of the product.

Hayashi, K, Orita, M, Suzuki, Y, Sekiya, T

Bacillus subtilis gene coding for constitutive O6-methylguanine-DNA alkyltransferase.

Stimulation of intermolecular ligation with E. coli DNA ligase by high concentrations of monovalent cations in polyethylene glycol solutions.

We have cloned a Bacillus subtilis DNA fragment that could correct the defect in a constitutive O6-methylguanine-DNA alkyltransferase (Dat1). This fragment also corrected the hypersensitivity of the...

Hayashi, K, Nakazawa, M, Ishizaki, Y, Hiraoka, N, Obayashi, A

In the presence of high concentrations of the nonspecific polymer polyethylene glycol (PEG), intermolecular cohesive-end ligation with the DNA ligase from Escherichia coli was stimulated by high salt...

Activation of rat c-raf during transfection of hepatocellular carcinoma DNA.

Ishikawa, F, Takaku, F, Hayashi, K, Nagao, M, Sugimura, T

Rat c-raf was found to be activated in a transformant obtained with DNA of a hepatocellular carcinoma induced by 2-amino-3-methylimidazo[4,5-f]quinoline. This activated c-raf was cloned in a cosmid...

Organization of sequences related to U6 RNA in the human genome.

Hayashi, K

Small nuclear RNAs were isolated from human placenta and fractionated into individual molecular species. They were then iodinated with 125I and used as probes to screen the human genome. Of 2 x 10(4)...

Single-strand conformation polymorphism (SSCP) at the D8S86 locus

Iizuka, M., Hayashi, K., Sekiya, T.

Bacillus subtilis ada operon encodes two DNA alkyltransferases.