K. Kimura

Neutrino-Nucleus Reaction Cross Sections for Light Element Synthesis in Supernova Explosions (2008)

Yoshida, T., Suzuki, T., Chiba, S., Kajino, T., Yokomakura, H., Kimura, K., ...

The neutrino-nucleus reaction cross sections of 4He and 12C are evaluated using new shell model Hamiltonians. Branching ratios of various decay channels are calculated to evaluate the yields of Li,...

Leptin responses to bovine interferon- α and insulin in cattle (2008)

Soliman, M M, Desoki, A, Shabaan, Z, Kimura, K, Kheilo, K, Fattouh, I

Leptin is a protein synthesized and secreted mainly by adipose tissue. Peripheral administration of different inflammatory cytokines increases both leptin protein and mRNA expression in rodents. We...

Fabrication of high performance MgB2 wires by an internal Mg diffusion process (2007)

Hur, J. M., Togano, K., Matsumoto, A., Kumakura, H., Wada, H., Kimura, K.

We succeeded in the fabrication of high-Jc MgB2/Fe wires applying the internal Mg diffusion (IMD) process with pure Mg core and SiC addition. A pure Mg rod with 2 mm diameter was placed at the center...

Influence of elastic scattering of photoelectrons on angle-resolved x-ray photoelectron spectroscopy (2007)

Kimura, K, Nakajima, K, Conard, T, Vandervorst, W

Energy loss of slow C-60(+) ions during grazing scattering from a KCl(001) surface (2007)

Matsushita, T, Nakajima, K, Suzuki, M, Kimura, K

Effects of using two airway exchange catheters on laryngeal passage during change from a double-lumen tracheal tube to a single-lumen tracheal tube (2007)

Suzuki, A., Uraoka, M., Kimura, K., Sato, S.

Background A thin airway exchange catheter (AEC) is often used for changing from a double-lumen tracheal tube (DLT) to a single-lumen tracheal tube. However, passage of the tube into the trachea is...

Application Of 14C Wiggle-Matching To Support Dendrochronological Analysis In Japan (2007)

T. Nakamura, M. Okuno, K. Kimura, T. Mitsutani, H. Moriwaki, Y. Ishizuka, ...

14C wiggle-matching was applied to two wood samples closely related to geological and archaeological events with associated dendrochronological dates, to demonstrate the accuracy of 14C dating with...

Study on the usefulness of precise and simple dynamic balance tests for the evaluation of recovery from intravenous sedation with midazolam and propofol. (2007)

Fujisawa, T., Takuma, S., Koseki, H., Kimura, K., Fukushima, K.

Background and objective: Dynamic balance involving movement of the centre of gravity is important for the evaluation of street fitness after sedation. The purpose of this study was to compare the...

Study on the usefulness of precise and simple dynamic balance tests for the evaluation of recovery from intravenous sedation with midazolam and propofol. (2007)

Fujisawa, T., Takuma, S., Koseki, H., Kimura, K., Fukushima, K.

Background and objective: Dynamic balance involving movement of the centre of gravity is important for the evaluation of street fitness after sedation. The purpose of this study was to compare the...

Plasma leptin concentration in dogs : effects of body condition score, age, gender and breeds (2007)

Ishioka, K., Hosoya, K., Kitagawa, H., Shibata, H., Honjoh, T., Kimura, K., ...

Leptin is a cytokine produced by adipocytes, and plays a key role in the regulation of energy balance. In the present study, we measured plasma leptin concentrations of 166 normal and obese dogs...

Plasma leptin concentration in dogs: effects of body condition score, age, gender and breeds. (2007)

Ishioka, K., Hosoya, K., Kitagawa, H., Shibata, H., Honjoh, T., Kimura, K., ...

Leptin is a cytokine produced by adipocytes, and plays a key role in the regulation of energy balance. In the present study, we measured plasma leptin concentrations of 166 normal and obese dogs...

Grain refinement of high-purity FCC metals using ECAP (2007)

Horita, Z., Kishikawa, K., Kimura, K., Tatsumi, K., Langdon, T.G.

Energy loss of slow C-60(+) ions during grazing scattering from a KCl(001) surface (2007)

Matsushita, T., Nakajima, K., Suzuki, M., Kimura, K.

Neutralization of slow C-60(+) ions in front of KCl(001) surface (2007)

Tamehiro, S., Matsushita, T., Nakajima, K., Suzuki, M., Kimura, K.

The analysis of a thin SiO2/Si3N4/SiO2 stack: A comparative study of low-energy heavy ion elastic recoil detection, high-resolution Rutherford backscattering, and secondary ion mass spectrometry (2006)

Sajavaara, T, Janssens, T, Conard, T, ...

The analysis of thin films in the range of 10 nm and less has become very important in microelectronics. The goal of this article is an evaluation of low-energy TOF-ERDA (time-of-flight elastic...

Neutrino Oscillation Effects on Supernova Light Element Synthesis (2006)

Yoshida, T., Kajino, T., Yokomakura, H., Kimura, K., Takamura, A., Hartmann, D. H.

Neutrino oscillations affect light element synthesis through the neutrino-process in supernova explosions. The 7Li and 11B yields produced in a supernova explosion of a 16.2 solar-mass star model...

Si emission from the SiO2/Si interface during the growth of SiO2 in the HfO2/SiO2/Si structure (2006)

Ming, Z, Nakajima, K, Suzuki, M, Kimura, K, Uematsu, M, Torii, K, ...

Supernova Neutrino Nucleosynthesis of Light Elements with Neutrino Oscillations (2006)

Yoshida, T., Kajino, T., Yokomakura, H., Kimura, K., Takamura, A., Hartmann, D. H.

Light element synthesis in supernovae through neutrino-nucleus interactions, i.e., the nu-process, is affected by neutrino oscillations in the supernova environment. There is a resonance of 13-mixing...

Hybrid membrane bioreactor for water recycling and phosphorus recovery (2006)

Watanabe, Y., Kimura, K.

This paper deals with the performance of hybrid membrane bioreactor (MBR) combining the precoagulation/sedimentation and membrane bioreactor. The hybrid MBR not only produces the treated water with...

Hybrid membrane bioreactor for water recycling and phosphorus recovery (2006)

Watanabe, Y., Kimura, K.

This paper deals with the performance of hybrid membrane bioreactor (MBR) combining the precoagulation/sedimentation and membrane bioreactor. The hybrid MBR not only produces the treated water with...

Hybrid membrane bioreactor for water recycling and phosphorus recovery (2006)

Watanabe, Y., Kimura, K.

This paper deals with the performance of hybrid membrane bioreactor (MBR) combining the precoagulation/sedimentation and membrane bioreactor. The hybrid MBR not only produces the treated water with...

Thermo-sensitive colloidal crystals of silica spheres in the presence of large spheres with poly (N-isopropyl acrylamide) shells (2006)

Okubo, T., Mizutani, T., Okamoto, J., Kimura, K., Tsuchida, A., Tauer, K., ...

Insights into social insects from the genome of the honeybee Apis mellifera (2006)

Weinstock, GM, Robinson, GE, Gibbs, RA, Worley, KC, Evans, JD, Maleszka, R, ...

Here we report the genome sequence of the honeybee Apis mellifera, a key model for social behaviour and essential to global ecology through pollination. Compared with other sequenced insect genomes,...

Thermal stability of Gd2O3/Si(100) interfacial transition layer (2006)

Nohira, H, Yoshida, T, Okamoto, H, Shinagawa, S, Sakai, W, Nakajima, K, ...

Si emission from the SiO2/Si interface during the growth of SiO2 in the HfO2/SiO2/Si structure (2006)

Ming, Z, Nakajima, K, Suzuki, M, Kimura, K, Uematsu, M, Torii, K, ...

Lattice distortion at SiO2/Si(001) interface studied with high-resolution rutherford backscattering spectroscopy/channeling (2006)

Nakajima, K, Suzuki, M, Kimura, K, Yamamoto, M, Teramoto, A, Ohmi, T, ...

In-line aligned and bottom-up Ag nanorods for surface-enhanced Raman spectroscopy (2006)

Suzuki, M, Maekita, W, Wada, Y, Nakajima, K, Kimura, K, Fukuoka, T, ...

Study on orientation mechanisms of poly(vinylidenefluoride-trifluoroethylene) molecules aligned by atomic force microscopy (2006)

Kimura, K, Kobayashi, K, Yamada, H, Horiuchi, T, Ishida, K, Matsushige, K

Convoy electrons emitted by 2-MeV He+ ions at grazing incidence on KCl(001) (2006)

Nakajima, K, Nakamoto, A, Suzuki, M, Kimura, K

Two-dimensional carrier profiling on operating Si metal-oxide semiconductor field-effect transistor by scanning capacitance microscopy (2006)

Kimura, K, Kobayashi, K, Yamada, H, Matsushige, K, Usuda, K

Observation of the interfacial layer in HfO2(10 nm)/Si by high-resolution RBS in combination with grazing angle sputtering (2006)

Sakai, W, Nakajima, K, Suzuki, M, Kimura, K, Brijs, B

Observation of Si emission during thermal oxidation of Si(001) with high-resolution RBS (2006)

Hosoi, S, Nakajima, K, Suzuki, M, Kimura, K, Shimizu, Y, Fukatsu, S, ...

Accumulation of hydrogen near the interface between ultrathin SiO2 and Si(001) under ion irradiation in high-resolution elastic recoil detection (2006)

Nakajima, K, Imaizumi, R, Suzuki, M, Kimura, K

Measurement of the strain in strained-Si/Si0.79Ge0.21 with HRBS/channeling (2006)

Matsushita, T, Sakai, W, Nakajima, K, Suzuki, M, Kimura, K, Agarwal, A, ...

The analysis of a thin SiO2/Si3N4/SiO2 stack: A comparative study of low-energy heavy ion elastic recoil detection, high-resolution Rutherford backscattering, and secondary ion mass spectrometry (2006)

Brijs, B, Sajavaara, T, Giangrandi, S, Janssens, T, Conard, T, Arstila, K, ...

Vapor phase growth of Al whiskers induced by glancing angle deposition at high temperature (2006)

Suzuki, M, Nagai, K, Kinoshita, S, Nakajima, K, Kimura, K, Okano, T, ...

Observation of microstructure of hydrated Ca3SiO5 (2006)

Mori, K, Sato, T, Fukunaga, T, Oishi, K, Kimura, K, Iwase, K, ...

Insights into social insects from the genome of the honeybee Apis mellifera (2006)

Weinstock, GM, Robinson, GE, Gibbs, RA, Worley, KC, Evans, JD, Maleszka, R, ...

Here we report the genome sequence of the honeybee Apis mellifera, a key model for social behaviour and essential to global ecology through pollination. Compared with other sequenced insect genomes,...

Proinsulin C-peptide activates vagus efferent output in rats (2005)

Kimura, K., Niijima, A., Yoshida, R., Kitamura, T., Kamikawa, A., Furuya, D. T., ...

The aim of this study was to examine the effect of proinsulin C-peptide on the autonomic nervous systems in rats. Intravenous administration of C-peptide gradually increased electrophysiological...

Proinsulin C-peptide activates vagus efferent output in rats (2005)

Kimura, K., Niijima, A., Yoshida, R., Kitamura, T., Kamikawa, A., Furuya, D. T., ...

The aim of this study was to examine the effect of proinsulin C-peptide on the autonomic nervous systems in rats. Intravenous administration of C-peptide gradually increased electrophysiological...

Proinsulin C-peptide activates vagus efferent output in rats (2005)

Kimura, K., Niijima, A., Yoshida, R., Kitamura, T., Kamikawa, A., Furuya, D. T., ...

The aim of this study was to examine the effect of proinsulin C-peptide on the autonomic nervous systems in rats. Intravenous administration of C-peptide gradually increased electrophysiological...

Frequency-modulation atomic force microscopy at high cantilever resonance frequencies using the heterodyne optical beam deflection method (2005)

Fukuma, T, Kimura, K, Kobayashi, K, Matsushige, K, Yamada, H

High-Mass Cloud Cores in the eta Carinae Giant Molecular Cloud (2005)

Yonekura, Y., Asayama, S., Kimura, K., Ogawa, H., Kanai, Y., Yamaguchi, N., ...

We carried out an unbiased survey for massive dense cores in the giant molecular cloud associated with eta Carinae with the NANTEN telescope in 12CO, 13CO, and C18O 1-0 emission lines. We identified...

15th International Workshop on Inelastic Ion-Surface Collisions (2005)

Kimura, K, Yamazaki, Y, Koshikawa, T, Morita, K

Neutralization rate for slow Ar+ ions in front of KCl(001) (2005)

Tsujioka, T, Tanaka, S, Nakamoto, A, Nakajima, K, Suzuki, M, Kimura, K

A new spectrometer for Rutherford backscattering spectrometry (2005)

Ichihara, C, Kobayashi, A, Inoue, K, Kimura, K

Frequency-modulation atomic force microscopy at high cantilever resonance frequencies using the heterodyne optical beam deflection method (2005)

Fukuma, T, Kimura, K, Kobayashi, K, Matsushige, K, Yamada, H

Direct formation of arrays of prolate Ag nanoparticles by dynamic oblique deposition (2005)

Suzuki, M, Maekita, W, Kishimoto, K, Teramura, S, Nakajima, K, Kimura, K, ...

Scanning capacitance force microscopy imaging of metal-oxide-semiconductor field effect transistors (2005)

Kimura, K, Kobayashi, K, Yamada, H, Matsushige, K, Usuda, K

Radiation damage induced by 5 keV Si+ ion implantation in strained-Si/Si0.8Ge0.2 (2005)

Matsushita, T, Sakai, W, Nakajima, K, Suzuki, M, Kimura, K, Agarwal, A, ...

Amorphous layer depth dependence on implant parameters during Si self-implantation (2005)

Lopez, P, Pelaz, L, Marques, LA, Barbolla, J, Gossmann, HJL, Agarwal, A, ...

The analysis of a thin SiO2/SixN1-x/SiO2 stack, a comparative study of low energy ERD with XPS, low energy SIMS, HRBS, HR-ERD (2005)

Brijs, Bert, Giangrandi, Simone; U0043091, Arstila, K, Bergmaier, A, Kimura, K, Conard, Thierry, ...

CP32: ASSESSMENT OF REGIONAL WALL MOTION DURING RIGHT-VENTRICULAR BIFOCAL PACING IN PATIENTS WITH SEVERE CONGESTIVE HEART FAILURE (2005)

Matsushita, K, Ishikawa, T, Sumita, S, Kobayashi, T, Kawasaki, N, Matsumoto, K, ...

Right-ventricular bifocal pacing (RVBF) was reported as a therapy of severe congestive heart failure. We evaluated regional wall motion by strain Doppler imaging in three patients with RVBF therapy...

Lack of circulating autoantibodies to bone morphogenetic protein receptor-II or activin receptor-like kinase 1 in mixed connective tissue disease patients with pulmonary arterial hypertension (2005)

Satoh, T., Kimura, K., Okano, Y., Hirakata, M., Kawakami, Y., Kuwana, M.

Objectives. To examine whether autoantibodies against bone morphogenetic protein receptor-II (BMPR-II) or activin receptor-like kinase 1 (ALK-1) are associated with pulmonary arterial hypertension...

Dynamic force microscopy at high cantilever resonance frequencies using heterodyne optical beam deflection method (2004)

Fukuma, T, Kimura, K, Kobayashi, K, Matsushige, K, Yamada, H

Auger neutralization rate for slow Ar+ ions in front of KCl(001) (2004)

Kimura, K, Tsujioka, T, Tanaka, S, Nakamoto, A, Nakajima, K, Suzuki, M

Errors in near-surface and interfacial profiling of boron and arsenic (2004)

Janssens, Tom, Brijs, Bert, Conard, Thierry, Frühauf, J, ...

Effect of nifekalant for out-of–hospital cardiac arrest with shock-resistant ventricular fibrillation (2004)

Toyama, H, Sugiyama, M, Tahara, Y, Toyoda, H, Kosuge, T, Moriwaki, Y, ...

No abstract available.

Auger neutralization rate for slow Ar+ ions in front of KCl(001) (2004)

Kimura, K, Tsujioka, T, Tanaka, S, Nakamoto, A, Nakajima, K, Suzuki, M

Errors in near-surface and interfacial profiling of boron and arsenic (2004)

Vandervorst, W, Janssens, T, Brijs, B, Conard, T, Huyghebaert, C, Fruhauf, J, ...

Atomic-scale depth profiling of composition, chemical structure and electronic band structure of La2O3/Si(100) interfacial transition layer (2004)

Nohira, H, Shiraishi, T, Takahashi, K, Hattori, T, Kashiwagi, I, Ohshima, C, ...

Characterization of HfO2/Si(001) interface with high-resolution Rutherford backscattering spectroscopy (2004)

Nakajima, K, Joumori, S, Suzuki, M, Kimura, K, Osipowicz, T, Tok, KL, ...

Orientation control of ferroelectric polymer molecules using contact-mode AFM (2004)

Kimura, K, Kobayashi, K, Yamada, H, Horiuchi, T, Ishida, K, Matsushige, K

Quality of SiO2 and of SiGe formed by oxidation of Si/Si0.7Ge0.3 heterostructure using atomic oxygen at 400 degrees C (2004)

Nohira, H, Kuroiwa, T, Nakamura, A, Hirose, Y, Hirose, Y, Mitsui, J, ...

Simulating structure and optical response of vacuum evaporated porous rugate filters (2004)

Kaminska, K, Suzuki, M, Kimura, K, Taga, Y, Robbie, K

Orientation control of high-density polyethylene molecular chains using atomic force microscope (2004)

Kimura, K, Kobayashi, K, Yamada, H, Horiuchi, T, Ishida, K, Matsushige, K

Orientation control of molecular chains in polymers using atomic force microscopy (2004)

Kimura, K, Kobayashi, K, Yamada, H, Horiuchi, T, Ishida, K, Matsushige, K

Structure of ultrathin epitaxial CeO2 films grown on Si(111) (2004)

Joumori, S, Nakajima, K, Suzuki, M, Kimura, K, Nishikawa, Y, Matsushita, D, ...

Use of grazing angle sputtering for improving depth resolution in high resolution RBS (2004)

Sakai, W, Nakajima, K, Suzuki, M, Kimura, K

Composition, chemical structure, and electronic band structure of rare earth oxide/Si(100) interfacial transition layer (2004)

Hattori, T, Yoshida, T, Shiraishi, T, Takahashi, K, Nohira, H, Joumori, S, ...

Effects of surface track potential on secondary electron emission and surface stopping power (2004)

Kimura, K, Usui, S, Tsujioka, T, Tanaka, S, Nakajima, K, Suzuki, M

High-resolution RBS: a powerful tool for atomic level characterization (2004)

Kimura, K, Joumori, S, Oota, Y, Nakajima, K, Suzuki, M

Charge-state distribution of 400 keV He ions scattered from solid surfaces (2004)

Nakajima, K, Okura, Y, Suzuki, M, Kimura, K

Dynamic force microscopy at high cantilever resonance frequencies using heterodyne optical beam deflection method (2004)

Fukuma, T, Kimura, K, Kobayashi, K, Matsushige, K, Yamada, H

Formation of iron silicide on Si(001) studied by high resolution Rutherford backscattering spectroscopy (2004)

Kinoshita, K, Imaizumi, R, Nakajima, K, Suzuki, M, Kimura, K

Influence of electron capture and loss in the energy distribution of protons dissociated from fast H2+ molecules in carbon foils (2004)

Abril, I, Denton, CD, Barriga-Carrasco, MD, Garcia-Molina, R, Kimura, K, Arista, NR

Lack of circulating autoantibodies to bone morphogenetic protein receptor-II or activin receptor-like kinase 1 in mixed connective tissue disease patients with pulmonary arterial hypertension (2004)

Satoh, T., Kimura, K., Okano, Y., Hirakata, M., Kawakami, Y., Kuwana, M.

Objectives. To examine whether autoantibodies against bone morphogenetic protein receptor-II (BMPR-II) or activin receptor-like kinase 1 (ALK-1) are associated with pulmonary arterial hypertension...

Lack of circulating autoantibodies to bone morphogenetic protein receptor-II or activin receptor-like kinase 1 in mixed connective tissue disease patients with pulmonary arterial hypertension (2004)

Satoh, T., Kimura, K., Okano, Y., Hirakata, M., Kawakami, Y., Kuwana, M.

Objectives. To examine whether autoantibodies against bone morphogenetic protein receptor-II (BMPR-II) or activin receptor-like kinase 1 (ALK-1) are associated with pulmonary arterial hypertension...

Strain profiling of HfO2/Si(001) interface with high-resolution Rutherford backscattering spectroscopy (2003)

Nakajima, K, Joumori, S, Suzuki, M, Kimura, K, Osipowicz, T, Tok, KL, ...

Orientation control of poly(vinylidenefluoride-trifluoroethylene) crystals and molecules using atomic force microscopy (2003)

Kimura, K, Kobayashi, K, Yamada, H, Horiuchi, T, Ishida, K, Matsushige, K

Association Between Retained Placenta and Impaired Neutrophil Function in Dairy Cows (2003)

Kimura, K, Goff, JP, Reinhardt, TA, Sato, S, Tyler, HD

No abstract available.

Clinical significance of S100A4 and E-cadherin related adhesion molecules (2003)

Endo, Y., Kimura, K., Yonemura, Y., Sasaki, T.

Determination of molecular weight of heparin by size exclusion chromatography with universal calibration (2003)

Guo, X., Condra, M., Kimura, K., Berth, G., Dautzenberg, Herbert, Dubin, P. L.

Two-dimensional dopant profiling by scanning capacitance force microscopy (2003)

Kimura, K, Kobayashi, K, Yamada, H, Matsushige, K

Molecular effect on projected range in ultralow-energy ion implantation (2003)

Kimura, K, Oota, Y, Nakajima, K, Suzuki, M, Aoki, T, Matsuo, J, ...

Biodegradable gelatin hydrogel potentiates the angiogenic effect of fibroblast growth factor 4 plasmid in rabbit hindlimb ischemia (2003)

Kasahara, H, Tanaka, E, Fukuyama, N, Sato, E, Sakamoto, H, Tabata, Y, ...

High-resolution depth profiling of ultrashallow boron implants in silicon using high-resolution RBS (2003)

Kimura, K, Oota, Y, Nakajima, K, Buyuklimanli, TH

Strain profiling of HfO2/Si(001) interface with high-resolution Rutherford backscattering spectroscopy (2003)

Nakajima, K, Joumori, S, Suzuki, M, Kimura, K, Osipowicz, T, Tok, KL, ...

SIMS and high-resolution RBS analysis of ultrathin SiOxNy films (2003)

Kimura, K, Nakajima, K, Kobayashi, H, Miwa, S, Satori, K

Energy loss of 15-keV Arq+ (q=1-3) ions reflected from a KCl(001) surface (2003)

Nakajima, K, Nakamura, M, Tsujioka, T, Kimura, K

Orientation control of poly(vinylidenefluoride-trifluoroethylene) crystals and molecules using atomic force microscopy (2003)

Kimura, K, Kobayashi, K, Yamada, H, Horiuchi, T, Ishida, K, Matsushige, K

Compositional transition layer in SiO2/Si interface observed by high-resolution RBS (2003)

Kimura, K, Nakajima, K

Recent developments in nuclear methods in support of semiconductor characterization (2003)

Bender, Hugo, Janssens, Tom, Nakajima, K, ...

Advanced characterization of high-k materials: A nuclear approach (2002)

Nauwelaerts, S, Caymax, M, Nakajima, K, ...

The determination of the composition of thin (1.5-3 nm) high-k layers ZrO2/Al2O3 becomes more and more important in microelectronics. High resolution Rutherford backscattering spectrometry and high...

Exact Formula of Probability and CP Violation for Neutrino Oscillations in Matter (2002)

Kimura, K., Takamura, A., Yokomakura, H.

Within the framework of the standard three neutrino scenario, we derive an exact and simple formula of the oscillation probability $P(\nu_e \to \nu_{\mu})$ in constant matter by using a new method....

Substrate Dependence in the Growth of Three-Dimensional Gold Nanoparticle Superlattices (2002)

Sato, S., Yamamoto, N., Yao, H., Kimura, K.

Three-dimensional superlattices consisting of gold nanoparticles were grown at air/suspension or suspension/solid interfaces. The growth of superlattices was found to be strongly dependent on...

Advanced characterization of high-k materials: A nuclear approach (2002)

Brijs, B, Huyghebaert, C, Nauwelaerts, S, Caymax, M, Vandervorst, W, Nakajima, K, ...

Surface segregation of Ge during Si growth on Ge/Si(001) at low temperature observed by high-resolution RBS (2002)

Nakajima, K, Hosaka, N, Hattori, T, Kimura, K

Release of nitrogen from SiOxNy films during RBS measurement (2002)

Kimura, K, Nakajima, K, Kobayashi, H, Miwa, S, Satori, K

Hydrogen analysis of CVD homoepitaxial diamond films by high-resolution elastic recoil detection (2002)

Kimura, K, Nakajima, K, Yamanaka, S, Hasegawa, M, Okushi, H

Ion scattering on crystalline surfaces: Effects of surface track potential on secondary electron emission (2002)

Kimura, K, Usui, S, Maeda, K, Nakajima, K

Hydrogen depth-profiling in chemical-vapor-deposited diamond films by high-resolution elastic recoil detection (2001)

Kimura, K, Nakajima, K, Yamanaka, S, Hasegawa, M, Okushi, H

Initial oxidation process on Si(001) studied by high-resolution Rutherford backscattering spectroscopy (2001)

Nakajima, K, Okazaki, Y, Kimura, K

Oxidation of Si(001) observed by high-resolution RBS (2001)

Kimura, K, Nakajima, K, Okazaki, Y

Nitrogen profile in SiOxNy prepared by thermal nitridation of ozone oxide (2001)

Nakajima, K, Kimura, K, Kurokawa, A, Ichimura, S, Fukuda, H

Initial oxidation process on Si(001) studied by high-resolution Rutherford backscattering spectroscopy (2001)

Nakajima, K, Okazaki, Y, Kimura, K

Hydrogen depth-profiling in chemical-vapor-deposited diamond films by high-resolution elastic recoil detection (2001)

Kimura, K, Nakajima, K, Yamanaka, S, Hasegawa, M, Okushi, H

Anomalous surface amorphization of Si(001) induced by 3-5 keV Ar+ ion bombardment (2001)

Nakajima, K, Toyofuku, H, Kimura, K

Quantification and depth profiling of a ZrO2 (2nm)/A1203 (1nm) layer with NRA, RBS, HRBS, HERD (2001)

Brijs, Bert, Huyghebaert, Cedric; U0032387, Nauwelaerts, Sophie; U0034720, Caymax, Matty, Vandervorst, Wilfried; U0008850, Nakajima, K, ...

Advanced RBS analysis of thin films in micro-electronics (2001)

Deleu, Jeroen, Nakajima, K, Kimura, K, ...

Optimal atrioventricular delay setting determined by evoked QT interval in patients with implanted stimulus-T-driven DDDR pacemakers (2001)

Ishikawa, T., Sugano, T., Sumita, S., Nakagawa, T., Hanada, K., Kosuge, M., ...

Cardiac function is improved by optimizing the atrioventricular (AV) delay. An automatic optimizing function of AV delay may be necessary to achieve the most favourable haemodynamic state in paced...

Secondary-electron emission by 0.5-MeV/u H, He, and Li ions specularly reflected from a SnTe(001) surface: Possibility of the surface track potential reducing the secondary-electron yield at a semiconductor surface (2000)

Kimura, K, Usui, S, Nakajima, K

Non-Steroidal Anti-Inflammatory Drug Toxicity in the Upper Gastrointestinal Tract (2000)

Sung, J. J. Y., Russell, R. I., Yeomans, N., Chan, F. K. L., Chen, S. I., Fock, K. M., ...

Non-steroidal anti-inflammatory drug (NSAID) toxicity in the upper gastrointestinal tract is the most common serious drug-induced toxicity reported to drug regulatory authorities. In the last two...

Non-Steroidal Anti-Inflammatory Drug Toxicity in the Upper Gastrointestinal Tract (2000)

Sung, J. J. Y., Russell, R. I., Yeomans, N., Chan, F. K. L., Chen, S. I., Fock, K. M., ...

Non-steroidal anti-inflammatory drug (NSAID) toxicity in the upper gastrointestinal tract is the most common serious drug-induced toxicity reported to drug regulatory authorities. In the last two...

Matter Enhancement of T Violation in Neutrino Oscillation (2000)

Yokomakura, H., Kimura, K., Takamura, A.

We study the matter enhancement of T violation in neutrino oscillation with three generations. The magnitude of T violation is proportional to Jarlskog factor J. Recently, the elegant relation,...

Schematic Method for Estimation of CP Asymmetry in Neutrino Oscillation (2000)

Kimura, K., Takamura, A.

Within the framework of three generations of leptons the schematical method for estimating CP asymmetry in neutrino oscillations is considered. We introduce a unitarity triangle corresponding to...

Energy loss of fragment protons dissociated from 0.2- and 0.5-MeV/amu H-2(+) ions incident in carbon foils (2000)

Susuki, Y, Fritz, M, Kimura, K, Mannami, M, Garcia-Molina, R, Abril, I

Total charge-changing cross sections for neutron-rich light nuclei (2000)

Chulkov, L V, Bochkarev, O V, Cortina-Gil, D, Geissel, H, Hellström, M, Ivanov, M, ...

Secondary-electron emission by MeV He ions reflected from a SnTe(001) surface: Separation of above- and below-surface processes (2000)

Kimura, K, Ooki, S, Andou, G, Nakajima, K

Polyelectrolyte-micelle coacervation. Effects of micelle surface charge density, polymer molecular weight, and polymer/surfactant ratio (2000)

Wang, Y., Kimura, K., Dubin, P.L., Jaeger, W.

Non-Steroidal Anti-Inflammatory Drug Toxicity in the Upper Gastrointestinal Tract (2000)

Sung, J. J. Y., Russell, R. I., Yeomans, N., Chan, F. K. L., Chen, S. I., Fock, K. M., ...

Non-steroidal anti-inflammatory drug (NSAID) toxicity in the upper gastrointestinal tract is the most common serious drug-induced toxicity reported to drug regulatory authorities. In the last two...

Nitrogen depth profiling in ultrathin silicon oxynitride films with high-resolution rutherford backscattering spectroscopy (2000)

Kimura, K, Nakajima, K, Okazaki, Y, Kobayashi, H, Miwa, S, Satori, K

Characterization of ultra thin oxynitrides: A general approach (2000)

Brijs, B, Deleu, J, Conard, T, De Witte, H, Vandervorst, W, Nakajima, K, ...

Secondary-electron emission by 0.5-MeV/u H, He, and Li ions specularly reflected from a SnTe(001) surface: Possibility of the surface track potential reducing the secondary-electron yield at a semiconductor surface (2000)

Kimura, K, Usui, S, Nakajima, K

Intermixing at Ge/Si(001) interfaces studied by high-resolution RBS (2000)

Nakajima, K, Konishi, A, Kimura, K

Oxidation of Si(001) surfaces studied by high-resolution rutherford backscattering spectroscopy (2000)

Nakajima, K, Okazaki, Y, Kimura, K

Secondary electron emission from surface channeled protons at a KCl(001) surface (2000)

Andou, G, Nakajima, K, Kimura, K

Surface-plasmon-assisted secondary-electron emission from an atomically flat LiF(001) surface (2000)

Kimura, K, Andou, G, Nakajima, K

Stopping power of a KCl(001) surface for low energy Ne atoms (2000)

Nakajima, K, Sonobe, S, Kimura, K

Secondary-electron emission by MeV He ions reflected from a SnTe(001) surface: Separation of above- and below-surface processes (2000)

Kimura, K, Ooki, S, Andou, G, Nakajima, K

Energy loss of fragment protons dissociated from 0.2- and 0.5-MeV/amu H-2(+) ions incident in carbon foils (2000)

Susuki, Y, Fritz, M, Kimura, K, Mannami, M, Garcia-Molina, R, Abril, I

Non-steroidal anti-inflammatory drug toxicity in the upper gastrointestinal tract (2000)

Sung, J.J., Russell, R. I., Yeomans, N., Chan, F. K., Chen, S. L., Fock, K. M., ...

Non-Steroidal Anti-Inflammatory Drug Toxicity in the Upper Gastrointestinal Tract (2000)

Sung, J. J. Y., Russell, R. I., Yeomans, N., Chan, F. K. L., Chen, S. I., Fock, K. M., ...

Non-steroidal anti-inflammatory drug (NSAID) toxicity in the upper gastrointestinal tract is the most common serious drug-induced toxicity reported to drug regulatory authorities. In the last two...

Advanced RBS analysis of thin films in micro-electronics (2000)

Brijs, Bert, Deleu, Jeroen, Huygebaert, C, Nauwelaerts, Sophie, Vandervorst, Wilfried; U0008850, Kimura, K

Characterization of ultra thin oxynitrides: a general approach (2000)

Deleu, Jeroen, Conard, Thierry, De Witte, Hilde, Nakajima, K, ...

Sinus node recovery time assessment by the overdrive suppression test employing an intravenous injection of disopyramide phosphate (2000)

Ishikawa, T., Sumita, S., Kimura, K., Kikuchi, M., Kosuge, M., Endo, T., ...

Although sinus node recovery time (SNRT) assessment by the overdrive suppression test (ODST) is important in detecting sick sinus syndrome (SSS), its sensitivity is still inadequate. We have...

Brief communication. Fifty microsatellite markers for Japanese quail (2000)

Kayang, BB, Inoue-Murayama, M, Nomura, A, Kimura, K, Takahashi, H, Mizutani, M, ...

A Japanese quail genomic library enriched for (CA/GT)n simple sequence was screened and positive clones were sequenced. Fifty original microsatellite sequences were isolated that consisted mainly of...

Chemiluminescence underestimates nitric oxide concentration in the presence of potent inhalation anaesthetics (2000)

Liu, R., Ishibe, Y., Okazaki, N., Kimura, K.

We investigated the effect of potent inhalation anaesthetics on nitric oxide (NO) concentration measured by the chemiluminescence method. We found that the NO concentration was increasingly...

Emission angle dependence of the nuclear temperature and free nucleon density in light projectile-induced reactions (1999)

Murata, J, Haseno, M, Kimura, K, Kosuge, F, Kubohara, R, Mihara, S, ...

Exact Parametrization of Majorana Neutrino Mass Matrix with Large Mixing (1999)

Kimura, K., Takamura, A.

Under the assumption that the neutrinos are Majorana particles we study how the lepton mass matrices can be transformed into the simple form which has the same physical quantities by removing...

Effects of salt on polyelectrolyte - micelle coacervation (1999)

Wang, Y., Kimura, K., Huang, Q., Dubin, P.L., Jaeger, W.

Characterization of ultra thin layers by Rutherford backscattering spectrometry (1999)

Deleu, Jeroen, Conard, Thierry, Li, H, Loo, Roger, Caymax, Matty, ...

Characterization of ultra thin oxynitrides, a general approach (1999)

Brijs, Bert, Deleu, Jeroen, Conard, Thierry, De Witte, Hilde, Vandervorst, Wilfried; U0008850, Nakajima, K, ...

Possible associations of rectal carcinoma with Schistosoma japonicum infection and membranous nephropathy: a case report with a review (1999)

Matsuda, K, Masaki, T, Ishii, S, Yamashita, H, Watanabe, T, Nagawa, H, ...

Barminomycin forms GC-specific adducts and virtual interstrand crosslinks with DNA (1999)

Perrin, LC, Cullinane, C, Kimura, K, Phillips, DR

Linkage and association of atopic asthma to markers on chromosome 13 in the Japanese population (1999)

Kimura, K, Noguchi, E, Shibasaki, M, Arinami, T, Yokouchi, Y, Takeda, K, ...

Relationship between atrioventricular delay, QT interval and cardiac function in patients with implanted DDD pacemakers (1999)

Ishikawa, T., Sugano, T., Sumita, S., Kimura, K., Kikuchi, M., Kosuge, M., ...

QT interval may change when cardiac function is improved by optimizing the atrioventricular the (AV) delay. The relationship between AV delay, QT interval and cardiac function in patients with...

STUDY ON T5 TREATMENT FOR IMPROVING DIMENSIONAL STABILITIES OF ALUMINUM ALLOY CASTINGS--STUDIES ON HEAT TREATMENTS OF ALUMINUM ALLOY CASTINGS (1ST REPORT). (1998)

KIMURA,K., MURAKI,M., MAYAKAWA,T.

STUDY ON T7 TREATMENT FOR IMPROVING DIMENSIONAL STABILITIES OF ALUMINUM ALLOY CASTINGS--STUDIES ON HEAT TREATMENTS OF ALUMINUM ALLOY CASTINGS (2ND REPORT). (1998)

KIMURA,K., MURAKI,M., HAYAKAWA,T.

Ultra-Fine Equiaxed Grain Refinement by Hydrogenation in Titanium Alloys. (1998)

Yoshimura, H., Kimura, K., Hayashi, M., Ishii, M., Takamura, J.

Abstract in Japanese.

Single Crystal Growth and Mechanical Properties of MoSi2 and WSi2. (1998)

Hirano, T., Nakamura, M., Kimura, K., Umakoshi, Y.

HIGH PURITY SINGLE CRYSTALS OF MoSi2 and WSi2 were grown in a floating zone (FZ) furnace that was modified into a high vacuum furnace; the grown crystals were of good quality due to the low grown...

An Analysis of Deformation, Temperature, and Microstructure for Hot Extruded Titanium Alloy. (1998)

Kimura, K., Ishii, M., Yoshimura, H.

During hot extrusion, the microstructure and resultant mechanical properties of materials are subjected to considerable change due to adiabatic local heat generation. in this work, strain,...

Single Crystal Growth and Mechanical Properties of MoSi2 and WSi2. (1998)

Hirano, T., Nakamura, M., Kimura, K., Umakoshi, Y.

A floating zone (FZ) furnace was modified into a high vacuum type furnace in order to grow high-purity single crystals of MoSi2 and WSi2. The impurity levels of the grown MoSi2 single crystals were...

High Temperature Deformation Behaviour of MoSi2 and WSi2 Single Crystals. (1998)

Kimura, K., Nakamura, M., Hirano, T.

High temperature deformation behavior of MoSi2 and WSi2 single crystals, which both oriented near and near , have been studied by compression tests over the temperature range of 1100 to 1500 C in a...

Experimental Study of Echo Directivity for Surface SH Wave and SH Wave Angle Probes, (1998)

Takahashi, M., Hoshino, M., Kimura, K.

Echo directivity was experimentally studied for surface SH wave probes and SH wave angle probes. Frequencies used in the experiment were 5MHz and 2MHz, the angles of refraction 90 degrees and 70...

Comparative growth kinetics of SiGe in a commercial reduced pressure chemical vapour deposition EPI reactor and anomalies during growth of thin Si layers on SiGe (1998)

Loo, Roger, Brijs, Bert, Howard, Dave, Kimura, K, ...

c-Myc gene single-strand binding protein-1, MSSP-1, suppresses transcription of alpha-smooth muscle actin gene in chicken visceral smooth muscle cells (1998)

Kimura, K, Saga, H, Hayashi, K, Obata, H, Chimori, Y, Ariga, H, ...

Three cases with familial adenomatous polyposis diagnosed as having malignant lesions in the course of a long-term trial using docosahexanoic acid (DHA)-concentrated fish oil capsules (1998)

Akedo, I, Ishikawa, H, Nakamura, T, Kimura, K, Takeyama, I, Suzuki, T, ...

Adiabatic connection between the RVB State and the ground state of the half filled periodic Anderson model (1997)

Kimura, K., Hatsugai, Y., Kohmoto, M.

A one-parameter family of models that interpolates between the periodic Anderson model with infinite repulsion at half-filling and a model whose ground state is exactly the Resonating-Valence-Bond...

Collimation of the e^+e^- annihilation event (1997)

Kimura, K., Tesima, K.

The collimation $C$ of a hadronic event in the e^+e^- annihilation is defined as the average of $\cos\theta$, $C=$, where $\theta$ is the angle of each hadron measured from the thrust axis, and the...

Mg K-Edge XAFS Study of Silica-Magnesia Systems (1997)

Yoshida, H., Yoshida, T., Tanaka, T., Funabiki, T., Yoshida, S., Abe, T., ...

Mg K-edge XAFS study was carried out to clarify the local structure of silica-magnesia systems prepared in four ways ; by impregnation of silica with an aqueous solution of magnesium nitrate or with...

Mg K-Edge XAFS Study of Silica-Magnesia Systems (1997)

Yoshida, H., Yoshida, T., Tanaka, T., Funabiki, T., Yoshida, S., Abe, T., ...

Mg K-edge XAFS study was carried out to clarify the local structure of silica-magnesia systems prepared in four ways ; by impregnation of silica with an aqueous solution of magnesium nitrate or with...

Mg K-Edge XAFS Study of Silica-Magnesia Systems (1997)

Yoshida, H., Yoshida, T., Tanaka, T., Funabiki, T., Yoshida, S., Abe, T., ...

Mg K-edge XAFS study was carried out to clarify the local structure of silica-magnesia systems prepared in four ways ; by impregnation of silica with an aqueous solution of magnesium nitrate or with...

A level-one representation of the quantum affine superalgebra $\U_q(\hat{\frak{sl}}(M+1|N+1))$ (1996)

Kimura, K., Shiraishi, J., Uchiyama, J.

A level-one representation of the quantum affine superalgebra $\U_q(\hat{\frak{sl}}(M+1|N+1))$ and vertex operators associated with the fundamental representations are constructed in terms of free...

Effect of a low-protein diet on expression of non-muscle type myosin heavy-chain isoforms in glomeruli of rats with puromycin aminonucleoside nephrosis (1996)

Koide, H., Nakamura, T., Kimura, K., Ebihara, I., Nagai, R., Tomino, Y.

Background. We reported that an embryonic type of non-muscle-type myosin heavy-chain isoform (SMemb) may be a molecular marker for phenotypic alteration in initial glomerular injury and that...

Corrections to Angular Ordering in Multiple Hadroprodroproduction (1995)

Kimura, K., Kitazawa, M., Tesima, K.

One of the key ideas in describing the multiparticle production at high energies in the perturbative QCD is the angular ordering in successive soft-gluon emission. We analyse the angular distribution...

Measurements of fragments produced in target multifragmentation using Bragg-curve counters (1995)

Ochiishi, H, Ito, H, Kimura, K, Kouda, S, Morinobu, S, Murakami, T, ...

Application of Bragg-curve counters to a target multifragmentation measurement (1995)

Ochiishi, H, Ito, H, Kimura, K, Kouda, S, Murakami, T, Shimooka, M, ...

Study of the levels in $^{17}$C above the $^{16}$C + neutron threshold (1995)

Raimann, G., Ozawa, A., Boyd, R. N., Chloupek, F. R., Fujimaki, M., Kimura, K., ...

The $\beta$-delayed neutron decay of $^{17}$B was studied using a radioactive ion beam. The neutron energies, measured via time-of-flight, give information on states in $^{17}$C above the $^{16}$C +...

Comparison of pinning parameters between low-Tc superconductors and YBa§2Cu§3O§7§-§d§e§l§t§a. (1995)

Küpfer, H., Zhukov, A.A., Kresse, R., Meier-Hirmer, R., Jahn, W., Wolf, T., ...

Physical Review B, 52(1995) S.7689-700

Energy spectra and angular distribution of intermediate mass fragments emitted in Au\/Ag(p,X) reactions with E$^{p}$ = 12 GeV: the first result of the KEK - 12 GeV - PS experiments - E288 (1994)

Tanaka, K H, Yamanoi, Y, Ochiishi, H, Akiyoshi, H, Kouda, S, Nakamura, H, ...

Shielding current and granularity in melt textured YBa§2Cu§3O§7 from AC flux profile and DC magnetization measurement. (1994)

Kresse, R., Kuepfer, H., Meier-Hirmer, R., Matsushita, T., Kimura, K.

Freyhardt, H.C. [Hrsg.]

Effect of reversible fluxoid motion on magnetization in small superconductors. (1994)

Matsushita, T., Otabe, E.S., Ohtani, N., Kimura, K., Hashimoto, M., Küpfer, H.

Bando, Y. [Hrsg.]

Multiplicity with a Thrust Cut (1993)

Kimura, K., Tesima, K.

We evaluate the multiplicity of hadrons in the $e^+e^-$-annihilation at a given thrust $T$ in the modified leading-log approximation, including $O(\sqrt{\alpha_s})$ corrections. The calculation is...

MX2; 3'-deamino-3'-morpholino-13-deoxy-10-hydroxycarminomycin (KRN8602) in refractory metastatic breast cancer: results of a preliminary phase II trial (1993)

Watanabe, T, Narabayashi, M, Haga, S, Yamada, Y, Kawamura, E, Enomoto, K, ...

PLASMA CONCENTRATIONS OF LIGNOCAINE AFTER OBTURATOR NERVE BLOCK COMBINED WITH SPINAL ANAESTHESIA IN PATIENT'S UNDERGOING TRANSURETHRAL RESECTION PROCEDURES (1992)

FUJITA, Y., KIMURA, K., FURUKAWA, Y., TAKAORI, M.

Bilateral obturator nerve block has become a widely accepted technique to avoid adductor contraction during transurethral resection of prostate or bladder tumours. However, little is known about...

Imaginary AC susceptibility in superconducting Y-Ba-Cu-O. (1992)

Matsushita, T., Otabe, E.S., Ni, B., Kimura, K., Hashimoto, M., Kuepfer, H.

Physica C, 196(1992) S.98-104

Power supply constraints in megabit DRAMs of the future (1987)

Itoh, K., Kimura, K.

Megabit DRAM power supply is described in terms of power dissipation, reliability for small transistors, and memory cell operating margin. Such recently developed 1 Mb techniques as CMOS and...

Power supply constraints in megabit DRAMs of the future (1987)

Itoh, K., Kimura, K.

Megabit DRAM power supply is described in terms of power dissipation, reliability for small transistors, and memory cell operating margin. Such recently developed 1 Mb techniques as CMOS and...

Power supply constraints in megabit DRAMs of the future (1987)

Itoh, K., Kimura, K.

Megabit DRAM power supply is described in terms of power dissipation, reliability for small transistors, and memory cell operating margin. Such recently developed 1 Mb techniques as CMOS and...

Abstracts of scientific presentations (1986)

Clark, J., Munitz, H. A., Benjamin, S. B., Frager, J., Janower, M. L., Wolf, E. L., ...

Peer Reviewed

Heme-heme magnetic interaction of cytochrome c3 studied by Mössbauer effect (1980)

Utuno, M., Ôno, K., Kimura, K., Inokuchi, H., Yagi, T.

A Mössbauer effect study was carried out on cytochrome c3 to investigate the heme-heme magnetic interaction. Results observed in the spectrum of partially reduced cytochrome c3 at 4.2 K shows that a...

Heme-heme magnetic interaction of cytochrome c3 studied by Mössbauer effect (1980)

Utuno, M., Ôno, K., Kimura, K., Inokuchi, H., Yagi, T.

A Mössbauer effect study was carried out on cytochrome c3 to investigate the heme-heme magnetic interaction. Results observed in the spectrum of partially reduced cytochrome c3 at 4.2 K shows that a...

Heme-heme magnetic interaction of cytochrome c3 studied by Mössbauer effect (1980)

Utuno, M., Ôno, K., Kimura, K., Inokuchi, H., Yagi, T.

A Mössbauer effect study was carried out on cytochrome c3 to investigate the heme-heme magnetic interaction. Results observed in the spectrum of partially reduced cytochrome c3 at 4.2 K shows that a...

Studies on the oligomeric structure of yeast aldehyde dehydrogenase by cross-linking with bifunctional reagents (1978)

Tamaki, N., Kimura, K., Hama, T.

Development of the high-gradient electrostatic accelerator techniques in the Kyushu University tandem (1977)

Isoya, A., Kuroyanagi, T., Nakajima, Y., Nakashima, T., Maki, T., Kato, N., ...

At Kyushu university a 10 MV tandem accelerator is just completed and being tested for the overall performance. The construction of this machine was started five years ago and the design principle...

Development of the high-gradient electrostatic accelerator techniques in the Kyushu University tandem (1977)

Isoya, A., Kuroyanagi, T., Nakajima, Y., Nakashima, T., Maki, T., Kato, N., ...

At Kyushu university a 10 MV tandem accelerator is just completed and being tested for the overall performance. The construction of this machine was started five years ago and the design principle...

Development of the high-gradient electrostatic accelerator techniques in the Kyushu University tandem (1977)

Isoya, A., Kuroyanagi, T., Nakajima, Y., Nakashima, T., Maki, T., Kato, N., ...

At Kyushu university a 10 MV tandem accelerator is just completed and being tested for the overall performance. The construction of this machine was started five years ago and the design principle...

THE SIMILARITIES IN THE ELECTRONIC ABSORPTION SPECTRA OF AROMATIC FREE RADICALS, RADICAL CATIONS, AND MOLECULES IN THEIR TRIPLET STATES. (1967)

Tsubomura, H., Kimura, K., Yamamoto, N., Nakato, Y., Tanaka, S., Arimitsu, S.

Author Institution: Department of Chemistry, Faculty of Engineering Science

Proteolytic processing and membrane association of putative nonstructural proteins of hepatitis C virus.

Hijikata, M, Mizushima, H, Tanji, Y, Komoda, Y, Hirowatari, Y, Akagi, T, ...

By using a plasmid-based transient protein expression system in cultured cells and an in vitro transcription/translation system, we analyzed the proteolytic processing of the putative nonstructural...

Differentiation of thymocytes from CD3-CD4-CD8- through CD3-CD4-CD8+ into more mature stages induced by a thymic stromal cell clone.

Tatsumi, Y, Kumanogoh, A, Saitoh, M, Mizushima, Y, Kimura, K, Suzuki, S, ...

We have investigated the capacity of our established thymic stromal cell clone (MRL104.8a) or its derived factor(s) to induce the differentiation of immature thymocytes. Culture of purified adult...

c-Myc gene single-strand binding protein-1, MSSP-1, suppresses transcription of alpha-smooth muscle actin gene in chicken visceral smooth muscle cells.

Kimura, K, Saga, H, Hayashi, K, Obata, H, Chimori, Y, Ariga, H, ...

The expression of alpha-smooth muscle actin is coordinately regulated by positive and negative cis- elements in the promoter region. Although cis -elements and trans -acting factors involved in the...

Barminomycin forms GC-specific adducts and virtual interstrand crosslinks with DNA.

Perrin, L C, Cullinane, C, Kimura, K, Phillips, D R

The sequence specificity of the binding of barminomycin (SN-07 chromophore) to DNA was investigated using an in vitro transcription assay. It was found that this compound formed blockages to...

Molecular aspects of high-level resistance to sulbactam-cefoperazone in Klebsiella oxytoca clinical isolates.

Kimura, K, Arakawa, Y, Ohsuka, S, Ito, H, Suzuki, K, Kurokawa, H, ...

Nine Klebsiella oxytoca strains which demonstrated resistance to the combination of sulbactam and cefoperazone were isolated from geographically separate hospitals in Japan in 1995. Among them, K....

Detection of Lyme disease spirochetes in the skin of naturally infected wild sika deer (Cervus nippon yesoensis) by PCR.

Kimura, K, Isogai, E, Isogai, H, Kamewaka, Y, Nishikawa, T, Ishii, N, ...

We demonstrated the presence of Borrelia burgdorferi sensu lato DNA in the skin tissues of naturally infected wild sika deer, using PCR. The risk of transmission of B. burgdorferi sensu lato is...

Analysis of fecal populations of bifidobacteria and lactobacilli and investigation of the immunological responses of their human hosts to the predominant strains.

Kimura, K, McCartney, A L, McConnell, M A, Tannock, G W

The bifidobacterial and lactobacillus populations of fecal samples collected from 10 human subjects were studied. The numbers of bifidobacteria were similar in the fecal samples of all of the...

Prevalence of antibodies against Borrelia species in patients with unclassified uveitis in regions in which Lyme disease is endemic and nonendemic.

Kimura, K, Isogai, E, Isogai, H, Nishikawa, T, Masuzawa, T, Yoshikawa, K, ...

We studied 93 patients with unclassified uveitis from two regions in Japan (Hokkaido and Kanagawa) to assess the contribution of Borrelia species to this condition. The seroprevalence of antibody to...

Preparation and characterization of antibodies against mouse prion protein (PrP) peptides.

Yokoyama, T, Kimura, K, Tagawa, Y, Yuasa, N

Antisera were raised in rabbits against three peptides, representing amino acid sequences 150 to 159, 165 to 174, and 213 to 226 of mouse prion (PrP), which were synthesized by using a multiple...

Immunoreactivity of specific epitopes of PrPSc is enhanced by pretreatment in a hydrated autoclave.

Yokoyama, T, Momotani, E, Kimura, K, Yuasa, N

An abnormal protein (PrPSc) accumulates in animals affected with scrapie. Immunoblotting procedures have been used widely to detect PrPSc. Blotted membranes were subjected to pretreatment in a...

Platelet-activating-factor-mediated pathogenesis in Lyme disease.

Isogai, E, Kimura, K, Fujii, N, Nishikawa, T, Ishii, N, Postic, D, ...

This study describes a role of platelet-activating factor (PAF) as a potential inducer of inflammation in infection with Borrelia burgdorferi. Two approaches were taken. The first involved the use of...

In vivo induction of apoptosis and immune responses in mice by administration of lipopolysaccharide from Porphyromonas gingivalis.

Isogai, E, Isogal, H, Kimura, K, Fujii, N, Takagi, S, Hirose, K, ...

In vivo administration of Porphyromonas gingivalis lipopolysaccharide (Pg-LPS) to mice induced apoptosis before a specific immune response. Apoptosis was associated with the expression of...

Number of specific antibody-secreting cells in the peripheral blood among children with mycoplasma pneumonia.

Iseki, M, Takahashi, T, Kimura, K, Yamashita, R, Sasaki, T

Mycoplasma pneumoniae-specific antibody-secreting cells (ASCs) in the peripheral blood were enumerated with an enzyme-linked immunospot assay in 12 children with mycoplasma pneumonia. Those cells...

Genetic analysis of the chitinase system of Serratia marcescens 2170.

Watanabe, T, Kimura, K, Sumiya, T, Nikaidou, N, Suzuki, K, Suzuki, M, ...

To carry out a genetic analysis of the degradation and utilization of chitin by Serratia marcescens 2170, various Tn5 insertion mutants with characteristic defects in chitinase production were...

Cloning of the structural gene for Clostridium botulinum type C1 toxin and whole nucleotide sequence of its light chain component.

Kimura, K, Fujii, N, Tsuzuki, K, Murakami, T, Indoh, T, Yokosawa, N, ...

The toxigenicity of Clostridium botulinum type C1 is mediated by specific bacteriophages. DNA was extracted from one of these phages. Two DNA fragments, 3 and 7.8 kb, which produced the protein...

The N-terminal region of hepatitis C virus nonstructural protein 3 (NS3) is essential for stable complex formation with NS4A.

Satoh, S, Tanji, Y, Hijikata, M, Kimura, K, Shimotohno, K

Hepatitis C virus proteins are produced by proteolytic processing of the viral precursor polyprotein that is encoded in the largest open reading frame of the viral genome. Processing of the...

Clonal expansion of superantigen-reactive T cells is resistant to FK506 in mice with AIDS.

Yoshikai, Y, Kidokoro, H, Kimura, K, Aoki, Y, Makino, M, Hiromatsu, K

Subcutaneous injection of FK506 (10 mg/kg of body weight) completely blocked the clonal expansion of staphylococcal enterotoxin A (SEA)-reactive T cells in healthy (control) mice after SEA injection...

The N-terminal region of hepatitis C virus-encoded NS5A is important for NS4A-dependent phosphorylation.

Asabe, S I, Tanji, Y, Satoh, S, Kaneko, T, Kimura, K, Shimotohno, K

We previously showed that two proteins, a 56-kDa protein (p56) and a 58-kDa protein (p58), are produced from the hepatitis C virus (HCV) nonstructural 5A region (NS5A) and that the production of p58...

Characterization of bacteriophage nucleic acids obtained from Clostridium botulinum types C and D.

Fujii, N, Oguma, K, Yokosawa, N, Kimura, K, Tsuzuki, K

Nontoxigenic strains of Clostridium botulinum types C and D are converted to toxigenic strains by infection with specific Tox+ bacteriophages. The nucleic acids were extracted from five converting...

Nucleotide sequence of the beta-cyclodextrin glucanotransferase gene of alkalophilic Bacillus sp. strain 1011 and similarity of its amino acid sequence to those of alpha-amylases.

Kimura, K, Kataoka, S, Ishii, Y, Takano, T, Yamane, K

The nucleotide sequence of the gene for cyclodextrin glucanotransferase of alkalophilic Bacillus sp. strain 1011 was determined. The deduced amino acid sequence at the NH2-terminal side of the enzyme...

Analysis of N-terminal processing of hepatitis C virus nonstructural protein 2.

Mizushima, H, Hijikata, M, Tanji, Y, Kimura, K, Shimotohno, K

We determined the partial amino (N)-terminal amino acid sequence of hepatitis C virus p21 (nonstructural protein 2 [NS2]). Cleavage at the p21 (NS2) N terminus depended on the presence of microsomal...

Two hepatitis C virus glycoprotein E2 products with different C termini.

Mizushima, H, Hijikata, M, Asabe, S, Hirota, M, Kimura, K, Shimotohno, K

Processing of the boundary region between the putative structural and nonstructural regions of the hepatitis C virus precursor polyprotein was analyzed by in vitro translation using reticulocyte...

Substrate requirements of hepatitis C virus serine proteinase for intermolecular polypeptide cleavage in Escherichia coli.

Komoda, Y, Hijikata, M, Sato, S, Asabe, S, Kimura, K, Shimotohno, K

Using as substrates a series of chimeric proteins containing various fragments of the hepatitis C virus precursor polyprotein between Escherichia coli maltose binding protein and dihydrofolate...

Two distinct proteinase activities required for the processing of a putative nonstructural precursor protein of hepatitis C virus.

Hijikata, M, Mizushima, H, Akagi, T, Mori, S, Kakiuchi, N, Kato, N, ...

Gene products of hepatitis C virus (HCV), a possible major causative agent of posttransfusion non-A, non-B hepatitis, are considered to be produced from a precursor polyprotein via proteolytic...

Effects of pH of the medium on flagellation of Vibrio parahaemolyticus.

Kimura, K, Tateiri, S, Iida, H

Formation of the lateral flagella by Vibrio parahaemolyticus was inhibited under an alkaline condition of the medium. However, flagellation of the polar monotrichous flagellum was not affected in the...

In vitro antibacterial activity of a new quinolone, NM394.

Ozaki, M, Matsuda, M, Tomii, Y, Kimura, K, Kazuno, K, Kitano, M, ...

NM394 is a new 6-fluoroquinolone antibacterial agent with a tricyclic structure which has a bridge that connects the N-1 and C-2 positions of the quinolone. The antibacterial activity of NM394...

In vivo evaluation of NM441, a new thiazeto-quinoline derivative.

Ozaki, M, Matsuda, M, Tomii, Y, Kimura, K, Segawa, J, Kitano, M, ...

NM441 is a lipophilic prodrug of a new thiazeto-quinoline carboxylic acid derivative NM394, and when it is administered orally it is readily absorbed and hydrolyzed to its parent compound. After oral...

Establishment of a monoclonal antibody recognizing an antigenic site common to Clostridium botulinum type B, C1, D, and E toxins and tetanus toxin.

Tsuzuki, K, Yokosawa, N, Syuto, B, Ohishi, I, Fujii, N, Kimura, K, ...

The partial amino acid sequence of the light-chain (Lc) component of Clostridium botulinum type C1 toxin was determined. The sequence was quite similar to those of the other types of botulinum and...

Experimental Borrelia garinii infection of Japanese quail.

Isogai, E, Tanaka, S, Braga, I S, Itakura, C, Isogai, H, Kimura, K, ...

Japanese quail inoculated subcutaneously with Borrelia garinii responded to infection. B. garinii was reisolated mainly from skin and randomly from several organs between 7 and 56 days...

Binding of Clostridium botulinum type C neurotoxin to different neuroblastoma cell lines.

Yokosawa, N, Kurokawa, Y, Tsuzuki, K, Syuto, B, Fujii, N, Kimura, K, ...

Binding of type C neurotoxin (C1 toxin) from Clostridium botulinum (strain Stockholm) to neuroblastoma cell lines was studied by using biotinylated anti-toxin antibody and avidin-biotinylated...

Cloning and complete nucleotide sequence of the gene for the main component of hemagglutinin produced by Clostridium botulinum type C.

Tsuzuki, K, Kimura, K, Fujii, N, Yokosawa, N, Indoh, T, Murakami, T, ...

In Clostridium botulinum types C and D, phage conversion to toxin and hemagglutinin (HA) production has been reported. DNA was extracted from a converting type C Stockholm phage, c-st, and a fragment...

Characteristic alteration in the nuclear DNA polymerase activity during the cell division cycle of Saccharomyces cerevisiae.

Tsuchiya, E, Kimura, K, Miyakawa, T, Fukui, S

Specific activity of the intranuclear DNA polymerase in cdc-mutant cells of Saccharomyces cerevisiae was found to be characteristically changed by arrest in their specific stage of cell division...

Four different monoclonal antibodies against type C1 toxin of Clostridium botulinum.

Oguma, K, Agui, T, Syuto, B, Kimura, K, Iida, H, Kubo, S

Monoclonal antibodies against type C1 toxin produced by Clostridium botulinum type C strain Stockholm (C-ST) were prepared by fusion of BALB/c myeloma cells P3X63-Ag8, with spleen cells from the mice...

EGF or PDGF receptors activate atypical PKClambda through phosphatidylinositol 3-kinase.

Akimoto, K, Takahashi, R, Moriya, S, Nishioka, N, Takayanagi, J, Kimura, K, ...

Overexpression of a TPA-insensitive PKC member, an atypical protein kinase C (aPKClambda), results in an enhancement of the transcriptional activation of TPA response element (TRE) in cells...

Different preparations of zymosan induce glycogenolysis independently in the perfused rat liver. Involvement of mannose receptors, peptide-leukotrienes and prostaglandins.

Kimura, K, Shiota, M, Mochizuki, K, Ohta, M, Sugano, T

Zymosan (non-boiled) induced glycogenolysis biphasically, with no lag time, in the perfused rat liver. After the zymosan was boiled, it could be separated into two fractions, both of which stimulated...

Phosphorylation of high mobility group 1 protein by phospholipid-sensitive Ca2+-dependent protein kinase from pig testis.

Kimura, K, Katoh, N, Sakurada, K, Kubo, S

Phospholipid-sensitive Ca2+-dependent protein kinase was partially purified from total particulate fraction of pig testis. The enzyme phosphorylated high mobility group 1 protein (HMG 1), one of the...

Proinsulin C-peptide rapidly stimulates mitogen-activated protein kinases in Swiss 3T3 fibroblasts: requirement of protein kinase C, phosphoinositide 3-kinase and pertussis toxin-sensitive G-protein.

Kitamura, T, Kimura, K, Jung, B D, Makondo, K, Okamoto, S, Cañas, X, ...

It has been demonstrated that proinsulin C-peptide possesses several biological activities and that its specific binding sites are present on the surface of cell membranes. However, the molecular and...

Successful segmental intestinal transplantation in enterectomized pigs.

Kimura, K, LaRosa, C A, Blank, M A, Jaffe, B M

The aim of this study was to determine whether short-segment jejunal allografts maintained the viability and nutritional status of outbred recipient pigs treated with low-dose cyclosporine. The...

Evolution of Hybrid Dysgenesis Potential following P Element Contamination in Drosophila Melanogaster

Kidwell, M. G., Kimura, K., Black, D. M.

P elements were introduced into M strain genomes by chromosomal contamination (transposition) from P strain chromosomes under conditions of P-M hybrid dysgenesis. A number of independently maintained...

Clinical significance of S100A4 and E-cadherin related adhesion molecules

Endo, Y., Kimura, K., Yonemura, Y., Sasaki, T.

Proteolytic processing and membrane association of putative nonstructural proteins of hepatitis C virus.

Hijikata, M, Mizushima, H, Tanji, Y, Komoda, Y, Hirowatari, Y, Akagi, T, ...

By using a plasmid-based transient protein expression system in cultured cells and an in vitro transcription/translation system, we analyzed the proteolytic processing of the putative nonstructural...

Differentiation of thymocytes from CD3-CD4-CD8- through CD3-CD4-CD8+ into more mature stages induced by a thymic stromal cell clone.

Tatsumi, Y, Kumanogoh, A, Saitoh, M, Mizushima, Y, Kimura, K, Suzuki, S, ...

We have investigated the capacity of our established thymic stromal cell clone (MRL104.8a) or its derived factor(s) to induce the differentiation of immature thymocytes. Culture of purified adult...

c-Myc gene single-strand binding protein-1, MSSP-1, suppresses transcription of alpha-smooth muscle actin gene in chicken visceral smooth muscle cells.

Kimura, K, Saga, H, Hayashi, K, Obata, H, Chimori, Y, Ariga, H, ...

The expression of alpha-smooth muscle actin is coordinately regulated by positive and negative cis- elements in the promoter region. Although cis -elements and trans -acting factors involved in the...

Barminomycin forms GC-specific adducts and virtual interstrand crosslinks with DNA.

Perrin, L C, Cullinane, C, Kimura, K, Phillips, D R

The sequence specificity of the binding of barminomycin (SN-07 chromophore) to DNA was investigated using an in vitro transcription assay. It was found that this compound formed blockages to...

Molecular aspects of high-level resistance to sulbactam-cefoperazone in Klebsiella oxytoca clinical isolates.

Kimura, K, Arakawa, Y, Ohsuka, S, Ito, H, Suzuki, K, Kurokawa, H, ...

Nine Klebsiella oxytoca strains which demonstrated resistance to the combination of sulbactam and cefoperazone were isolated from geographically separate hospitals in Japan in 1995. Among them, K....

Detection of Lyme disease spirochetes in the skin of naturally infected wild sika deer (Cervus nippon yesoensis) by PCR.

Kimura, K, Isogai, E, Isogai, H, Kamewaka, Y, Nishikawa, T, Ishii, N, ...

We demonstrated the presence of Borrelia burgdorferi sensu lato DNA in the skin tissues of naturally infected wild sika deer, using PCR. The risk of transmission of B. burgdorferi sensu lato is...

Analysis of fecal populations of bifidobacteria and lactobacilli and investigation of the immunological responses of their human hosts to the predominant strains.

Kimura, K, McCartney, A L, McConnell, M A, Tannock, G W

The bifidobacterial and lactobacillus populations of fecal samples collected from 10 human subjects were studied. The numbers of bifidobacteria were similar in the fecal samples of all of the...

Prevalence of antibodies against Borrelia species in patients with unclassified uveitis in regions in which Lyme disease is endemic and nonendemic.

Kimura, K, Isogai, E, Isogai, H, Nishikawa, T, Masuzawa, T, Yoshikawa, K, ...

We studied 93 patients with unclassified uveitis from two regions in Japan (Hokkaido and Kanagawa) to assess the contribution of Borrelia species to this condition. The seroprevalence of antibody to...

Preparation and characterization of antibodies against mouse prion protein (PrP) peptides.

Yokoyama, T, Kimura, K, Tagawa, Y, Yuasa, N

Antisera were raised in rabbits against three peptides, representing amino acid sequences 150 to 159, 165 to 174, and 213 to 226 of mouse prion (PrP), which were synthesized by using a multiple...

Immunoreactivity of specific epitopes of PrPSc is enhanced by pretreatment in a hydrated autoclave.

Yokoyama, T, Momotani, E, Kimura, K, Yuasa, N

An abnormal protein (PrPSc) accumulates in animals affected with scrapie. Immunoblotting procedures have been used widely to detect PrPSc. Blotted membranes were subjected to pretreatment in a...

Platelet-activating-factor-mediated pathogenesis in Lyme disease.

Isogai, E, Kimura, K, Fujii, N, Nishikawa, T, Ishii, N, Postic, D, ...

This study describes a role of platelet-activating factor (PAF) as a potential inducer of inflammation in infection with Borrelia burgdorferi. Two approaches were taken. The first involved the use of...

In vivo induction of apoptosis and immune responses in mice by administration of lipopolysaccharide from Porphyromonas gingivalis.

Isogai, E, Isogal, H, Kimura, K, Fujii, N, Takagi, S, Hirose, K, ...

In vivo administration of Porphyromonas gingivalis lipopolysaccharide (Pg-LPS) to mice induced apoptosis before a specific immune response. Apoptosis was associated with the expression of...

Number of specific antibody-secreting cells in the peripheral blood among children with mycoplasma pneumonia.

Iseki, M, Takahashi, T, Kimura, K, Yamashita, R, Sasaki, T

Mycoplasma pneumoniae-specific antibody-secreting cells (ASCs) in the peripheral blood were enumerated with an enzyme-linked immunospot assay in 12 children with mycoplasma pneumonia. Those cells...

Genetic analysis of the chitinase system of Serratia marcescens 2170.

Watanabe, T, Kimura, K, Sumiya, T, Nikaidou, N, Suzuki, K, Suzuki, M, ...

To carry out a genetic analysis of the degradation and utilization of chitin by Serratia marcescens 2170, various Tn5 insertion mutants with characteristic defects in chitinase production were...

Cloning of the structural gene for Clostridium botulinum type C1 toxin and whole nucleotide sequence of its light chain component.

Kimura, K, Fujii, N, Tsuzuki, K, Murakami, T, Indoh, T, Yokosawa, N, ...

The toxigenicity of Clostridium botulinum type C1 is mediated by specific bacteriophages. DNA was extracted from one of these phages. Two DNA fragments, 3 and 7.8 kb, which produced the protein...

The N-terminal region of hepatitis C virus nonstructural protein 3 (NS3) is essential for stable complex formation with NS4A.

Satoh, S, Tanji, Y, Hijikata, M, Kimura, K, Shimotohno, K

Hepatitis C virus proteins are produced by proteolytic processing of the viral precursor polyprotein that is encoded in the largest open reading frame of the viral genome. Processing of the...

Clonal expansion of superantigen-reactive T cells is resistant to FK506 in mice with AIDS.

Yoshikai, Y, Kidokoro, H, Kimura, K, Aoki, Y, Makino, M, Hiromatsu, K

Subcutaneous injection of FK506 (10 mg/kg of body weight) completely blocked the clonal expansion of staphylococcal enterotoxin A (SEA)-reactive T cells in healthy (control) mice after SEA injection...

The N-terminal region of hepatitis C virus-encoded NS5A is important for NS4A-dependent phosphorylation.

Asabe, S I, Tanji, Y, Satoh, S, Kaneko, T, Kimura, K, Shimotohno, K

We previously showed that two proteins, a 56-kDa protein (p56) and a 58-kDa protein (p58), are produced from the hepatitis C virus (HCV) nonstructural 5A region (NS5A) and that the production of p58...

Characterization of bacteriophage nucleic acids obtained from Clostridium botulinum types C and D.

Fujii, N, Oguma, K, Yokosawa, N, Kimura, K, Tsuzuki, K

Nontoxigenic strains of Clostridium botulinum types C and D are converted to toxigenic strains by infection with specific Tox+ bacteriophages. The nucleic acids were extracted from five converting...

Nucleotide sequence of the beta-cyclodextrin glucanotransferase gene of alkalophilic Bacillus sp. strain 1011 and similarity of its amino acid sequence to those of alpha-amylases.

Kimura, K, Kataoka, S, Ishii, Y, Takano, T, Yamane, K

The nucleotide sequence of the gene for cyclodextrin glucanotransferase of alkalophilic Bacillus sp. strain 1011 was determined. The deduced amino acid sequence at the NH2-terminal side of the enzyme...

Analysis of N-terminal processing of hepatitis C virus nonstructural protein 2.

Mizushima, H, Hijikata, M, Tanji, Y, Kimura, K, Shimotohno, K

We determined the partial amino (N)-terminal amino acid sequence of hepatitis C virus p21 (nonstructural protein 2 [NS2]). Cleavage at the p21 (NS2) N terminus depended on the presence of microsomal...

Two hepatitis C virus glycoprotein E2 products with different C termini.

Mizushima, H, Hijikata, M, Asabe, S, Hirota, M, Kimura, K, Shimotohno, K

Processing of the boundary region between the putative structural and nonstructural regions of the hepatitis C virus precursor polyprotein was analyzed by in vitro translation using reticulocyte...

Substrate requirements of hepatitis C virus serine proteinase for intermolecular polypeptide cleavage in Escherichia coli.

Komoda, Y, Hijikata, M, Sato, S, Asabe, S, Kimura, K, Shimotohno, K

Using as substrates a series of chimeric proteins containing various fragments of the hepatitis C virus precursor polyprotein between Escherichia coli maltose binding protein and dihydrofolate...

Two distinct proteinase activities required for the processing of a putative nonstructural precursor protein of hepatitis C virus.

Hijikata, M, Mizushima, H, Akagi, T, Mori, S, Kakiuchi, N, Kato, N, ...

Gene products of hepatitis C virus (HCV), a possible major causative agent of posttransfusion non-A, non-B hepatitis, are considered to be produced from a precursor polyprotein via proteolytic...

Effects of pH of the medium on flagellation of Vibrio parahaemolyticus.

Kimura, K, Tateiri, S, Iida, H

Formation of the lateral flagella by Vibrio parahaemolyticus was inhibited under an alkaline condition of the medium. However, flagellation of the polar monotrichous flagellum was not affected in the...

In vitro antibacterial activity of a new quinolone, NM394.

Ozaki, M, Matsuda, M, Tomii, Y, Kimura, K, Kazuno, K, Kitano, M, ...

NM394 is a new 6-fluoroquinolone antibacterial agent with a tricyclic structure which has a bridge that connects the N-1 and C-2 positions of the quinolone. The antibacterial activity of NM394...

In vivo evaluation of NM441, a new thiazeto-quinoline derivative.

Ozaki, M, Matsuda, M, Tomii, Y, Kimura, K, Segawa, J, Kitano, M, ...

NM441 is a lipophilic prodrug of a new thiazeto-quinoline carboxylic acid derivative NM394, and when it is administered orally it is readily absorbed and hydrolyzed to its parent compound. After oral...

Establishment of a monoclonal antibody recognizing an antigenic site common to Clostridium botulinum type B, C1, D, and E toxins and tetanus toxin.

Tsuzuki, K, Yokosawa, N, Syuto, B, Ohishi, I, Fujii, N, Kimura, K, ...

The partial amino acid sequence of the light-chain (Lc) component of Clostridium botulinum type C1 toxin was determined. The sequence was quite similar to those of the other types of botulinum and...

Experimental Borrelia garinii infection of Japanese quail.

Isogai, E, Tanaka, S, Braga, I S, Itakura, C, Isogai, H, Kimura, K, ...

Japanese quail inoculated subcutaneously with Borrelia garinii responded to infection. B. garinii was reisolated mainly from skin and randomly from several organs between 7 and 56 days...

Binding of Clostridium botulinum type C neurotoxin to different neuroblastoma cell lines.

Yokosawa, N, Kurokawa, Y, Tsuzuki, K, Syuto, B, Fujii, N, Kimura, K, ...

Binding of type C neurotoxin (C1 toxin) from Clostridium botulinum (strain Stockholm) to neuroblastoma cell lines was studied by using biotinylated anti-toxin antibody and avidin-biotinylated...

Cloning and complete nucleotide sequence of the gene for the main component of hemagglutinin produced by Clostridium botulinum type C.

Tsuzuki, K, Kimura, K, Fujii, N, Yokosawa, N, Indoh, T, Murakami, T, ...

In Clostridium botulinum types C and D, phage conversion to toxin and hemagglutinin (HA) production has been reported. DNA was extracted from a converting type C Stockholm phage, c-st, and a fragment...

Characteristic alteration in the nuclear DNA polymerase activity during the cell division cycle of Saccharomyces cerevisiae.

Tsuchiya, E, Kimura, K, Miyakawa, T, Fukui, S

Specific activity of the intranuclear DNA polymerase in cdc-mutant cells of Saccharomyces cerevisiae was found to be characteristically changed by arrest in their specific stage of cell division...

Four different monoclonal antibodies against type C1 toxin of Clostridium botulinum.

Oguma, K, Agui, T, Syuto, B, Kimura, K, Iida, H, Kubo, S

Monoclonal antibodies against type C1 toxin produced by Clostridium botulinum type C strain Stockholm (C-ST) were prepared by fusion of BALB/c myeloma cells P3X63-Ag8, with spleen cells from the mice...

EGF or PDGF receptors activate atypical PKClambda through phosphatidylinositol 3-kinase.

Akimoto, K, Takahashi, R, Moriya, S, Nishioka, N, Takayanagi, J, Kimura, K, ...

Overexpression of a TPA-insensitive PKC member, an atypical protein kinase C (aPKClambda), results in an enhancement of the transcriptional activation of TPA response element (TRE) in cells...

Different preparations of zymosan induce glycogenolysis independently in the perfused rat liver. Involvement of mannose receptors, peptide-leukotrienes and prostaglandins.

Kimura, K, Shiota, M, Mochizuki, K, Ohta, M, Sugano, T

Zymosan (non-boiled) induced glycogenolysis biphasically, with no lag time, in the perfused rat liver. After the zymosan was boiled, it could be separated into two fractions, both of which stimulated...

Phosphorylation of high mobility group 1 protein by phospholipid-sensitive Ca2+-dependent protein kinase from pig testis.

Kimura, K, Katoh, N, Sakurada, K, Kubo, S

Phospholipid-sensitive Ca2+-dependent protein kinase was partially purified from total particulate fraction of pig testis. The enzyme phosphorylated high mobility group 1 protein (HMG 1), one of the...

Evolution of Hybrid Dysgenesis Potential following P Element Contamination in Drosophila Melanogaster

Kidwell, M. G., Kimura, K., Black, D. M.

P elements were introduced into M strain genomes by chromosomal contamination (transposition) from P strain chromosomes under conditions of P-M hybrid dysgenesis. A number of independently maintained...

Proinsulin C-peptide rapidly stimulates mitogen-activated protein kinases in Swiss 3T3 fibroblasts: requirement of protein kinase C, phosphoinositide 3-kinase and pertussis toxin-sensitive G-protein.

Kitamura, T, Kimura, K, Jung, B D, Makondo, K, Okamoto, S, Cañas, X, ...

It has been demonstrated that proinsulin C-peptide possesses several biological activities and that its specific binding sites are present on the surface of cell membranes. However, the molecular and...

Successful segmental intestinal transplantation in enterectomized pigs.

Kimura, K, LaRosa, C A, Blank, M A, Jaffe, B M

The aim of this study was to determine whether short-segment jejunal allografts maintained the viability and nutritional status of outbred recipient pigs treated with low-dose cyclosporine. The...

Clinical significance of S100A4 and E-cadherin related adhesion molecules

Endo, Y., Kimura, K., Yonemura, Y., Sasaki, T.

Protein kinase C mediates the signal for interferon-gamma mRNA expression in cytotoxic T cells after their adhesion to laminin.

Li, Y Q, Kobayashi, M, Yuan, L, Wang, J, Matsushita, K, Hamada, J I, ...

A cytotoxic T-cell line, CTLL-2 cells, showed spreading after adhering to extracellular matrix proteins such as fibronectin (FN), laminin (LN) and hyarulonic acid (HA). The adhesion of CTLL-2 cells...

Location of membrane-bound hapten with different length spacers.

Kimura, K, Arata, Y, Yasuda, T, Kinosita, K, Nakanishi, M

Immunogenic activity of a lipid hapten is strongly dependent of the length and nature of the linker chain (spacer) connecting the hapten to the head group of the lipid. A derivative containing a very...

The effect of immunoglobulin G1 structure on macrophage binding to supported planar lipid monolayers.

Kimura, K, Nakanishi, M, Ueda, M, Ueno, J, Nariuchi, H, Furukawa, S, ...

We have studied the antibody-dependent binding of macrophages to supported planar lipid monolayers containing haptenated phospholipids (Tnp-Cap-DPPE). Eight monoclonal anti-TNP IgG1s, which had...

Th0-like CD4+ T cells protect mice with murine retrovirus-induced immunodeficiency syndrome (MAIDS) against co-infection with Listeria monocytogenes.

Hiromatsu, K, Nishimura, H, Kimura, K, Aoki, Y, Usami, J, Kobayashi, N, ...

We examined the host defence mechanism against infection with Listeria monocytogenes, a facultative intracellular bacterium, in mice with murine acquired immunodeficiency syndrome (MAIDS) caused by...

Differences in autoantibody response to Th/To between systemic sclerosis and other autoimmune diseases

Kuwana, M, Kimura, K, Hirakata, M, Kawakami, Y, Ikeda, Y

Methods: Serum samples from 1048 Japanese patients with various autoimmune diseases were screened for anti-Th/To antibodies using RNA and protein immunoprecipitation assays. The reactivity to RNase P...

Cytoskeletal changes in podocytes associated with foot process effacement in Masugi nephritis.

Shirato, I., Sakai, T., Kimura, K., Tomino, Y., Kriz, W.

Foot process effacement represents the most characteristic change in podocyte phenotype under a great variety of experimental as well as human glomerulopathies. It consists in simplification up to a...

Non-Steroidal Anti-Inflammatory Drug Toxicity in the Upper Gastrointestinal Tract

Sung, J. J. Y., Russell, R. I., Yeomans, N., Chan, F. K. L., Chen, S. I., Fock, K. M., ...

Non-steroidal anti-inflammatory drug (NSAID) toxicity in the upper gastrointestinal tract is the most common serious drug-induced toxicity reported to drug regulatory authorities. In the last two...

Dynamic studies on portal haemodynamics by scintiphotosplenoportography: flow patterns of portal circulation.

Kashiwagi, T, Kimura, K, Suematsu, T, Shichiri, M, Kamada, T, Abe, H

Scintiphotosplenoportography (SSP) was performed in 190 instances in 161 patients. No significant complications, such as severe pain or splenic haemorrhage, were encountered in any of the patients...

Inhibition of nuclear factor-κB activation improves the survival of rats with taurocholate pancreatitis

Satoh, A, Shimosegawa, T, Fujita, M, Kimura, K, Masamune, A, Koizumi, M, ...

Third Department of Internal Medicine, Tohoku University School of Medicine, Sendai, Miyagi, Japan

Rapid increase in plasma endothelin concentrations during percutaneous balloon dilatation of the mitral valve in patients with mitral stenosis.

Kinoshita, O, Yoshimi, H, Nagata, S, Ishikura, F, Kimura, K, Yamabe, T, ...

OBJECTIVE--To investigate the relation between plasma concentrations of immunoreactive endothelin and haemodynamic variables before and after percutaneous transvenous balloon dilatation of the mitral...

Retinitis pigmentosa with visual fluctuations and arrestin gene mutation

ISASHIKI, Y., OHBA, N., KIMURA, K., SONODA, S., KAKIUCHI, T., OZAWA, T.

Role of membrane-associated lymphotoxin (mLT) in the killing activity of lymphokine-activated killer (LAK) cells towards various tumour cell lines.

Horiuchi, A, Abe, Y, Miyake, M, Kimura, K, Hitsumoto, Y, Takeuchi, N, ...

Human lymphokine-activated killer (LAK) cells developed by an incubation of peripheral mononuclear cells with IL-2 express the membrane-associated lymphotoxin (LT)-related molecule (mLT). By a...

A duplicated PLP gene causing Pelizaeus-Merzbacher disease detected by comparative multiplex PCR.

Inoue, K., Osaka, H., Sugiyama, N., Kawanishi, C., Onishi, H., Nezu, A., ...

Pelizaeus-Merzbacher disease (PMD) is an X-linked dysmyelinating disorder caused by abnormalities in the proteolipid protein (PLP) gene, which is essential for oligodendrocyte differentiation and CNS...

Immunohistochemical and ultrastructural analysis of medullary carcinoma of the thyroid in relation to hormone production.

Kameya, T., Shimosato, Y., Adachi, I., Abe, K., Kasai, N., Kimura, K., ...

Eighteen cases of medullary carcinoma of the thyroid were analyzed immunohistochemically for calcitonin- and ACTH-containing cells, and tumor cells in 8 cases were examined by an electron microscope...

Clinical implications of persistent ST segment depression after admission in patients with non-ST segment elevation acute coronary syndrome

Kosuge, M, Kimura, K, Ishikawa, T, Shimizu, T, Hibi, K, Nozawa, N, ...

Dilated coronary arterial lesions in the late period after Kawasaki disease

Tsuda, E, Kamiya, T, Ono, Y, Kimura, K, Echigo, S

Objectives: There are two types of late coronary dilated lesions after Kawasaki disease: new aneurysms and expanding aneurysms. The development of coronary dilated lesions late after Kawasaki disease...

Developmental changes in beta-adrenoceptors, muscarinic cholinoceptors and Ca2+ channels in rat ventricular muscles.

Kojima, M., Ishima, T., Taniguchi, N., Kimura, K., Sada, H., Sperelakis, N.

1. In an attempt to explain the previous electrophysiological data on the ontogeny of beta-adrenergic and muscarinic cholinergic interactions on cardiac Ca2+ current, biochemical studies were...

Lung cancer in Japanese chromate workers.

Ohsaki, Y, Abe, S, Kimura, K, Tsuneta, Y, Mikami, H, Murao, M

We have treated ten patients with lung cancer among workers in a chromate factory between 1972 and 1976. Four further cases were also found through death certificates and medical records. Most were...

Chromium content of lungs of chromate workers with lung cancer.

Tsuneta, Y, Ohsaki, Y, Kimura, K, Mikami, H, Abe, S, Murao, M

The chromium content was measured in the lungs of chromate workers, obtained at necropsy in six patients and at surgery in two. The mean chromium content of peripheral lung tissue was 36.7 micrograms...

Assessment of autonomic nervous function in patients with vibration syndrome using heart rate variation and plasma cyclic nucleotides.

Harada, N, Kondo, H, Kimura, K

A case-control study was performed to investigate the autonomic nervous function in vibration syndrome. The subjects were 20 patients with a history of Raynaud's phenomenon (vibration white finger...

Atypical form of dural graft associated Creutzfeldt-Jakob disease: report of a postmortem case with review of the literature

Kimura, K, Nonaka, A, Tashiro, H, Yaginuma, M, Shimokawa, R, Okeda, R, ...

A postmortem case of an atypical form of dural graft associated Creutzfeldt-Jakob disease (CJD) is described. A 42 year old man developed progressive spastic paresis 163 months after a cadaveric dura...

Isolated pulmonary arteriovenous fistula without Rendu-Osler-Weber disease as a cause of cryptogenic stroke

Kimura, K, Minematsu, K, Nakajima, M

REM sleep motor dysfunction in multiple system atrophy: with special emphasis on sleep talk as its early clinical manifestation

Tachibana, N, Kimura, K, Kitajima, K, Shinde, A, Kimura, J, Shibasaki, H

Various neurodegenerative diseases involving brainstem structures as one of the main pathological lesions are reported to be associated with REM sleep behaviour disorder. Full blown REM sleep...

Development of posture in prone and supine positions during the prenatal period in low risk preterm infants.

Konishi, Y, Takaya, R, Kimura, K, Konishi, K, Fujii, Y, Saito, M, ...

The development of posture in the prone and supine positions was studied longitudinally in 10 low risk preterm infants between 31 and 39 weeks' postmenstrual age whose subsequent neurological...

Atrial fibrillation as a predictive factor for severe stroke and early death in 15 831 patients with acute ischaemic stroke

Kimura, K, Minematsu, K, Yamaguchi, T, T For,

Background: Atrial fibrillation (AF) is a common arrhythmia and a major risk factor for stroke.

The Optimal International Economic Integration: The Multiple Circular Cities approach.

Kimura, K.

economic integration ; cities

201T1 to 67Ga uptake ratio as an indicator for predicting tumour doubling time in human pulmonary neoplasms.

Togawa, T., Satoh, T., Hoshi, K., Haneda, K., Yonemoto, H., Kimura, K.

The expression of vascular endothelial growth factor C and its receptors in non-small cell lung cancer

Kajita, T, Ohta, Y, Kimura, K, Tamura, M, Tanaka, Y, Tsunezuka, Y, ...

Expression of vascular endothelial growth factor (VEGF)-C and that of its receptors were assessed in non-small cell lung cancer. Immunohistochemistry revealed positive VEGF-C expression in 38.7%...