K. Letwin

Publication List Details

Period

1988 - 1994

Number

17

Co-Authors

Immunolocalization of the Nuk receptor tyrosine kinase suggests roles in segmental patterning of the brain and axonogenesis (1994)

Henkemeyer, M, Marengere, LE, McGlade, J, Olivier, JP, Conlon, RA, Holmyard, DP, ...

Neural kinase (Nuk) encodes a murine receptor-like tyrosine kinase belonging to the Eph/Elk/Eck family. Protein localization studies indicate that during early embryogenesis Nuk is confined to the...

Immunolocalization of the Nuk receptor tyrosine kinase suggests roles in segmental patterning of the brain and axonogenesis (1994)

Henkemeyer, M, Marengere, LE, McGlade, J, Olivier, JP, Conlon, RA, Holmyard, DP, ...

Neural kinase (Nuk) encodes a murine receptor-like tyrosine kinase belonging to the Eph/Elk/Eck family. Protein localization studies indicate that during early embryogenesis Nuk is confined to the...

Novel protein-tyrosine kinase cDNAs related to fps/fes and eph cloned using anti-phosphotyrosine antibody (1988)

Letwin, K, Yee, SP, Pawson, Tony

A rat brain lambda gt11 cDNA expression library was screened with anti-phosphotyrosine antibody to identify recombinant clones that encode enzymatically active protein-tyrosine kinases. The inserts...

Novel protein-tyrosine kinase cDNAs related to fps/fes and eph cloned using anti-phosphotyrosine antibody (1988)

Letwin, K, Yee, SP, Pawson, Tony

A rat brain lambda gt11 cDNA expression library was screened with anti-phosphotyrosine antibody to identify recombinant clones that encode enzymatically active protein-tyrosine kinases. The inserts...

Characterization of elk, a brain-specific receptor tyrosine kinase.

Lhoták, V, Greer, P, Letwin, K, Pawson, T

The elk gene encodes a novel receptorlike protein-tyrosine kinase, which belongs to the eph subfamily. We have previously identified a partial cDNA encompassing the elk catalytic domain (K. Letwin,...

The FER gene is evolutionarily conserved and encodes a widely expressed member of the FPS/FES protein-tyrosine kinase family.

Pawson, T, Letwin, K, Lee, T, Hao, Q L, Heisterkamp, N, Groffen, J

We have recently isolated human and rat cDNAs (designated FER and flk, respectively) which encode nonreceptor protein-tyrosine kinases which are very similar to one another and related in sequence...

Multiple cDNAs encoding the esk kinase predict transmembrane and intracellular enzyme isoforms.

Douville, E M, Afar, D E, Howell, B W, Letwin, K, Tannock, L, Ben-David, Y, ...

A novel protein kinase, the Esk kinase, has been isolated from an embryonal carcinoma (EC) cell line by using an expression cloning strategy. Sequence analysis of two independent cDNA clones (2.97...

A mammalian protein kinase with potential for serine/threonine and tyrosine phosphorylation is related to cell cycle regulators.

Ben-David, Y, Letwin, K, Tannock, L, Bernstein, A, Pawson, T

In a screen of mouse erythroleukemia cDNA expression libraries with anti-phosphotyrosine antibodies, designed to isolate tyrosine kinase coding sequences, we identified several cDNAs encoding...

Tyr721 regulates specific binding of the CSF-1 receptor kinase insert to PI 3'-kinase SH2 domains: a model for SH2-mediated receptor-target interactions.

Reedijk, M, Liu, X, Letwin, K, Waterfield, M D, Hunter, T, ...

Efficient binding of active phosphatidylinositol (PI) 3'-kinase to the autophosphorylated macrophage colony stimulating factor receptor (CSF-1R) requires the noncatalytic kinase insert (KI) region of...

A mammalian dual specificity protein kinase, Nek1, is related to the NIMA cell cycle regulator and highly expressed in meiotic germ cells.

Letwin, K, Mizzen, L, Motro, B, Ben-David, Y, Bernstein, A, Pawson, T

Screening of mouse cDNA expression libraries with antibodies to phosphotyrosine resulted in repeated isolation of cDNAs that encode a novel mammalian protein kinase of 774 amino acids, termed Nek1....

Characterization of elk, a brain-specific receptor tyrosine kinase.

Lhoták, V, Greer, P, Letwin, K, Pawson, T

The elk gene encodes a novel receptorlike protein-tyrosine kinase, which belongs to the eph subfamily. We have previously identified a partial cDNA encompassing the elk catalytic domain (K. Letwin,...

The FER gene is evolutionarily conserved and encodes a widely expressed member of the FPS/FES protein-tyrosine kinase family.

Pawson, T, Letwin, K, Lee, T, Hao, Q L, Heisterkamp, N, Groffen, J

We have recently isolated human and rat cDNAs (designated FER and flk, respectively) which encode nonreceptor protein-tyrosine kinases which are very similar to one another and related in sequence...

Multiple cDNAs encoding the esk kinase predict transmembrane and intracellular enzyme isoforms.

Douville, E M, Afar, D E, Howell, B W, Letwin, K, Tannock, L, Ben-David, Y, ...

A novel protein kinase, the Esk kinase, has been isolated from an embryonal carcinoma (EC) cell line by using an expression cloning strategy. Sequence analysis of two independent cDNA clones (2.97...

A mammalian protein kinase with potential for serine/threonine and tyrosine phosphorylation is related to cell cycle regulators.

Ben-David, Y, Letwin, K, Tannock, L, Bernstein, A, Pawson, T

In a screen of mouse erythroleukemia cDNA expression libraries with anti-phosphotyrosine antibodies, designed to isolate tyrosine kinase coding sequences, we identified several cDNAs encoding...

Tyr721 regulates specific binding of the CSF-1 receptor kinase insert to PI 3'-kinase SH2 domains: a model for SH2-mediated receptor-target interactions.

Reedijk, M, Liu, X, Letwin, K, Waterfield, M D, Hunter, T, ...

Efficient binding of active phosphatidylinositol (PI) 3'-kinase to the autophosphorylated macrophage colony stimulating factor receptor (CSF-1R) requires the noncatalytic kinase insert (KI) region of...

A mammalian dual specificity protein kinase, Nek1, is related to the NIMA cell cycle regulator and highly expressed in meiotic germ cells.

Letwin, K, Mizzen, L, Motro, B, Ben-David, Y, Bernstein, A, Pawson, T

Screening of mouse cDNA expression libraries with antibodies to phosphotyrosine resulted in repeated isolation of cDNAs that encode a novel mammalian protein kinase of 774 amino acids, termed Nek1....