Genetic susceptibility to the respiratory effects of air pollution (2008)
Yang, I.A., Fong, K.M., Zimmerman , P.V., Holgate, S.T., Holloway, J.W.
Lung asbestos content in lung reseacted for primary lung cancer (2008)
Wright, C.M., Bowman, R. V., Tan, M.E., Maria Martins, McLachlan, R.E., Passmore, L.H., ...
Introduction: The majority of Australia's burden of lung cancer occurs in current or former tobacco smokers. To determine the possible contribution of asbestos exposure in Australians presenting with...
Gene-environmental interaction in asthma (2007)
Yang, I.A., Savarimuthu, S., Kim, S.T., Holloway, J.W., Bell, S.C., Fong, K.M.
Purpose of Review: Asthma is likely to result from the effects of environmental stimuli in genetically susceptible individuals. This review summarizes recent studies of gene-environmental interaction...
Chen, L., Meyers, D., Javorsky, G., Bursto, D., Lolekha, P., Lucas, M., ...
Objective: Administration of the beta-adrenergic receptor blocker carvedilol to patients with chronic heart failure leads to clinically significant benefits, including improvement in left ventricular...
Inhaled corticosteroids for stable chronic obstructive pulmonary disease (Review) (2007)
Yang, I. A., Fong, K. M., Sim, E. H. A., Black, P. N., Lasserson, T. J.
Background The role of inhaled corticosteroids (ICS) in chronic obstructive pulmonary disease ( COPD) has been the subject of much controversy. Major international guidelines recommend selective use...
Gene expression of lung squamous cell carcinoma reflects mode of lymph node involvement (2007)
Larsen, J.E., Pavey, S.J., Bowman, R., Yang, I.A., Clarke, B.E., Colosimo, M.L., ...
Tumour, node, metastasis staging is essential for lung cancer management. However, similarly staged cancers may have markedly different prognoses, indicating that stage cannot completely explain...
Gene expression signature predicts recurrence in lung adenocarcinoma (2007)
Larsen,J.E., Pavey, S., Passmore, L.H., Bowman, R.V., Hayward, N.K., Fong, K.M.
Expression profiling defines a recurrence signature in lung squamous cell carcinoma (2007)
Larsen, J. E., Pavey, S., Passmore, L. H., Bowman, R., Clarke, B. E., Hayward, N. K., ...
Lung cancer remains the leading cause of cancer death worldwide. Overall 5-year survival is similar to 10-15% and despite curative intent surgery, treatment failure is primarily due to recurrent...
Larsen, J.E., Hayward, N. K., Fong, K. M.
A Genomic Strategy to Refine Prognosis in Early-Stage NonSmall-Cell Lung Cancer (August 10. 2006:355:570-80). figure 4 presents an analysis of samples from a Cancer and Leukemia Group B (CALGB) 9761...
Chen, L., Meyers, D., Javorsky, G., Bursto, D., Lolekha, P., Lucas, M., ...
Objective: Administration of the beta-adrenergic receptor blocker carvedilol to patients with chronic heart failure leads to clinically significant benefits, including improvement in left ventricular...
Inhaled corticosteroids for stable chronic obstructive pulmonary disease (Review) (2007)
Yang, I. A., Fong, K. M., Sim, E. H. A., Black, P. N., Lasserson, T. J.
Background The role of inhaled corticosteroids (ICS) in chronic obstructive pulmonary disease ( COPD) has been the subject of much controversy. Major international guidelines recommend selective use...
Gene expression of lung squamous cell carcinoma reflects mode of lymph node involvement (2007)
Larsen, J.E., Pavey, S.J., Bowman, R., Yang, I.A., Clarke, B.E., Colosimo, M.L., ...
Tumour, node, metastasis staging is essential for lung cancer management. However, similarly staged cancers may have markedly different prognoses, indicating that stage cannot completely explain...
Gene expression signature predicts recurrence in lung adenocarcinoma (2007)
Larsen,J.E., Pavey, S., Passmore, L.H., Bowman, R.V., Hayward, N.K., Fong, K.M.
Expression profiling defines a recurrence signature in lung squamous cell carcinoma (2007)
Larsen, J. E., Pavey, S., Passmore, L. H., Bowman, R., Clarke, B. E., Hayward, N. K., ...
Lung cancer remains the leading cause of cancer death worldwide. Overall 5-year survival is similar to 10-15% and despite curative intent surgery, treatment failure is primarily due to recurrent...
Larsen, J.E., Fong, K. M., Hayward, N. K., Hayward, N. K.
A Genomic Strategy to Refine Prognosis in Early-Stage NonSmall-Cell Lung Cancer (August 10. 2006:355:570-80). figure 4 presents an analysis of samples from a Cancer and Leukemia Group B (CALGB) 9761...
Perfusion CT applications in lung cancer (2007)
Fong, K. M., Bowman, R. V., Yang, I. A., Miles, K. A.
This new text-atlas focuses on anatomy and procedural strategy for perfusion CT imaging in the diagnosis and management of cancer. It will use a combination of pictures and schematic diagrams that...
The role of Toll-like receptors and related receptors of the innate immune system in asthma (2006)
Yang, I.A., Fong, K.M., Holgate, S.T., Holloway, J.W.
Purpose of review: The biology of the innate immunity receptors is of central importance in the host response to the environment. Identifying genetic variants that alter the innate immune response is...
Expression and methylation pattern of TSLC1 cascade genes in lung carcinomas (2006)
Heller, G., Fong, K. M., Girard, L., Seidl, S., End-Pfutzenreuter, A., Lang, G., ...
TSLC1 (tumor suppressor in lung cancer-1, IGSF4) encodes a member of the immunoglobulin superfamily molecules, which is involved in cell-cell adhesion. TSLC1 is connected to the actin cytoskeleton by...
Expression and methylation pattern of TSLC1 cascade genes in lung carcinomas (2006)
Heller, G., Fong, K. M., Girard, L., Seidl, S., End-Pfutzenreuter, A., Lang, G., ...
TSLC1 (tumor suppressor in lung cancer-1, IGSF4) encodes a member of the immunoglobulin superfamily molecules, which is involved in cell-cell adhesion. TSLC1 is connected to the actin cytoskeleton by...
Tumors, Malignant: Bronchogenic Carcinoma (2006)
Fong, K. M., Bowman, R. V., Zimmerman, P. V.
Lung cancer is the most devastating, yet preventable, cause of premature cancer mortality and morbidity in the Western world. While death rates for all other major cancers have been stable or...
Tumors, Malignant: Overview (2006)
Fong, K. M., Bowman, R. V., Zimmerman, P. V.
Although the most common malignancies of the lung are primary bronchogenic carcinomas and metastatic tumors, a wide range of rarer tumor types can occur in humans. Newer techniques to establish...
Tumors, Malignant: Metastases from Lung Cancer (2006)
Fong, K. M., Clarke, B. E., Bowman, R. V.
Over half of the patients presenting with lung cancer have metastatic disease. The most common sites of metastatic involvement in lung cancer are regional lymph nodes, brain, bone, liver, and adrenal...
Tumors, Malignant: Carcinoma, Lymph Node Involvement (2006)
Fong, K. M., Windsor, M., Bowman, R. V., Duhig, E.
Metastasis to mediastinal or hilar lymph nodes by cancer (adenopathic carcinoma) is among the commonest causes of intrathoracic node enlargement in adults. As it represents relatively advanced...
Hematological Malignancies (2006)
Most hematological malignancies involving the thorax are lymphomas either Hodgkin or non-Hodgkin in type. These usually present with mediastinal masses in patients in their third and fourth decade,...
Cochrane systematic reviews of treatments for lung cancer (2005)
Fong, K.M., Yang, I.A., Zimmerman, P.V., Bowman, R.V.
Morbidity and mortality from lung cancer is a major burden to global health. The integration of expert clinical experience, patient preference and high-quality evidence, including Cochrane systematic...
Somatic Mutations of the HER2 Kinase Domain in Lung Adenocarcinomas (2005)
Shigematsu, H., Takahashi, T., Nomura, M., Majmudar, K., Suzuki, M., Lee, H., ...
Mutations in the epidermal growth factor receptor gene (EGFR) in lung cancers predict for sensitivity to EGFR kinase inhibitors. HER2 (also known as NEU, EGFR2, or ERBB2) is a member of the EGFR...
Mori, S., Ito, G., Usami, N., Yoshioka, H., Ueda, Y., Kodama, Y., ...
Mori, S., Ito, G., Usami, N., Yoshioka, H., Ueda, Y., Kodama, Y., ...
Mannose-binding lectin gene polymorphism predicts hospital admissions for COPD infections (2003)
Yang, I. A., Seeney, S. L., Wolter, J. M., Anders, E. M., McCormack, J. G., Tunnicliffe, A. M., ...
Infection frequently causes exacerbations of chronic obstructive pulmonary disease (COPD). Mannose-binding lectin (MBL) is a pattern-recognition receptor that assists in clearing microorganisms....
Mannose-binding lectin gene polymorphism predicts hospital admissions for COPD infections (2003)
Yang, I. A., Seeney, S. L., Wolter, J. M., Anders, E. M., McCormack, J. G., Tunnicliffe, A. M., ...
Infection frequently causes exacerbations of chronic obstructive pulmonary disease (COPD). Mannose-binding lectin (MBL) is a pattern-recognition receptor that assists in clearing microorganisms....
Lung cancer • 9: Molecular biology of lung cancer: clinical implications (2003)
Fong, K. M., Sekido, Y., Gazdar, A. F., Minna, J. D.
It has been hypothesised that clinically evident lung cancers have accumulated many different genetic or epigenetic abnormalities in oncogenes and/or tumour suppressor genes. This notion has...
Sarsero, D, Russell, F D, Lynham, J A, Rabnott, G, Yang, I, Fong, K M, ...
Two forms of the activated #1-adrenoceptor exist, one that is stabilized by (-)-noradrenaline and is sensitive to blockade by (-)-propranolol and another which is stabilized by partial agonists such...
Molenaar, P., Rabnott, G., Yang, I., Fong, K. M., Savarimuthu, S. M., Li, L., ...
OBJECTIVES The goal of this study was to determine whether the cardiostimulant effects of the endogenous beta(1)-adrenergic receptor (AR) agonist, (-)-norepinephrine are modified by polymorphic...
Quantification of pulmonary emphysema using high-resolution computed tomography (1999)
Yang, I., Slaughter, R., Roszkowski, A., Fong, K. M., Zimmerman, P. V.
b2 adrenergic receptor genotypes in severe asthma (1999)
Douglas, J. A., Yang, I., Rabnott, G. C., Tunnicliffe, A. M., McCarthy, J. B., Zimmerman, P. V., ...
GSTM1 genotypes in Australian patients with NSCLC (1999)
Gan, R., Yang, I., Tunnicliffe, A. M., Rabnott, G. C., Bowman, R., Zimmerman, P.V., ...
Health informatics in nursing education, research and quality assurance for asthma (1999)
Moloney, C., Fong, K. M., Yang, I., Reilly, R., Zimmerman, P. V.
b2 adrenoceptor genotypes and life-threatening asthma (1999)
Rabnott, G. C., Tunnicliffe, A. M., Yang, I. A., Douglas, J. A., Shaw, J., McCarthy, J. B., ...
GSTM1 and GSTP1 polymorphisms in chronic obstructive pulmonary disease (COPD) (1999)
Yang, I. A., Gan, R., Tunnicliffe, A. M., Rabnott, G. C., Slaughter, R., Zimmerman, P.V., ...
GSTM1 and GSTT1 genotypes in Australians with NSCLC (1999)
Gan, R., Yang, I. A., Tunnicliffe, A. M., Rabnott, G. C., Fong, K. M.
b2 adrenergic receptor genotypes in severe asthma (1999)
Douglas, J. A., Yang, I., Rabnott, G. C., Tunnicliffe, A. M., McCarthy, J. B., Zimmerman, P. V., ...
b2 adrenoceptor genotypes and life-threatening asthma (1999)
Rabnott, G. C., Tunnicliffe, A. M., Yang, I. A., Douglas, J. A., Shaw, J., McCarthy, J. B., ...
b2 adrenergic receptor genotypes in severe asthma (1999)
Douglas, J. A., Yang, I., Rabnott, G. C., Tunnicliffe, A. M., McCarthy, J. B., Zimmerman, P. V., ...
b2 adrenoceptor genotypes and life-threatening asthma (1999)
Rabnott, G. C., Tunnicliffe, A. M., Yang, I. A., Douglas, J. A., Shaw, J., McCarthy, J. B., ...
Quantification of pulmonary emphysema using high-resolution computed tomography (1999)
Yang, I., Slaughter, R., Roszkowski, A., Fong, K. M., Zimmerman, P. V.
GSTM1 genotypes in Australian patients with NSCLC (1999)
Gan, R., Yang, I., Tunnicliffe, A. M., Rabnott, G. C., Bowman, R., Zimmerman, P.V., ...
Health informatics in nursing education, research and quality assurance for asthma (1999)
Moloney, C., Fong, K. M., Yang, I., Reilly, R., Zimmerman, P. V.
GSTM1 and GSTP1 polymorphisms in chronic obstructive pulmonary disease (COPD) (1999)
Yang, I. A., Gan, R., Tunnicliffe, A. M., Rabnott, G. C., Slaughter, R., Zimmerman, P.V., ...
GSTM1 and GSTT1 genotypes in Australians with NSCLC (1999)
Gan, R., Yang, I. A., Tunnicliffe, A. M., Rabnott, G. C., Fong, K. M.
Gorham's syndrome: a usually fatal cause of pleural effusion treated successfully with radiotherapy.
McNeil, K. D., Fong, K. M., Walker, Q. J., Jessup, P., Zimmerman, P. V.
A 21 year old man presented with a right sided pleural effusion. Destruction of the 11th and 12th right ribs and adjacent vertebral bodies was noted on computed tomographic scanning. An open rib...
Fong, K M, McNeil, K D, Kennedy, K P, Matar, K S, Cole, P H, Partridge, J B
A 40 year old man presented with recurrent episodes of dyspnoea whilst swallowing solid food. He had undergone right pneumonectomy and thoracoplasty for recurrent pneumonias and empyema 23 years...
MYCL genotypes and loss of heterozygosity in non-small-cell lung cancer.
Fong, K. M., Kida, Y., Zimmerman, P. V., Smith, P. J.
Some studies have suggested that the S allele of the MYCL oncogene, which results from an intragenic EcoRI restriction fragment length polymorphism (RFLP), may be associated with cancer...
Geradts, J, Fong, K M, Zimmerman, P V, Minna, J D
The FHIT gene is located at a chromosomal site (3p14.2) which is commonly affected by translocations and deletions in human neoplasia. Although FHIT alterations at the DNA and RNA level are frequent...