K. Mark Ansel

Mouse Eri1 interacts with the ribosome and catalyzes 5.8S rRNA processing (2008)

Ansel, K. Mark, Pastor, William A., Rath, Nicola, Lapan, Ariya D., Glasmacher, Elke, Wolf, Christine, ...

Eri1 is a 3'-to-5' exoribonuclease conserved from fission yeast to humans. Here we show that Eri1 associates with ribosomes and ribosomal RNA (rRNA). Ribosomes from Eri1-deficient mice contain 5.8S...

MicroRNA profiling of the murine hematopoietic system (2005)

Monticelli, Silvia, Ansel, K Mark, Xiao, Changchun, Socci, Nicholas D, Krichevsky, Anna M, Thai, To-Ha, ...

Abstract Background MicroRNAs (miRNAs) are a class of recently discovered noncoding RNA genes that post-transcriptionally regulate gene expression. It is becoming clear that miRNAs play an important...

MicroRNA profiling of the murine hematopoietic system

Monticelli, Silvia, Ansel, K Mark, Xiao, Changchun, Socci, Nicholas D, Krichevsky, Anna M, Thai, To-Ha, ...

The first report of systematic miRNA profiling in cells of the hematopoietic system suggests that, in addition to regulating commitment to particular cellular lineages, miRNAs might have a general...

MicroRNA profiling of the murine hematopoietic system

Monticelli, Silvia, Ansel, K Mark, Xiao, Changchun, Socci, Nicholas D, Krichevsky, Anna M, Thai, To-Ha, ...

The first report of systematic miRNA profiling in cells of the hematopoietic system suggests that, in addition to regulating commitment to particular cellular lineages, miRNAs might have a general...

Aberrant T cell differentiation in the absence of Dicer

Muljo, Stefan A., Ansel, K. Mark, Kanellopoulou, Chryssa, Livingston, David M., Rao, Anjana, Rajewsky, Klaus

Dicer is an RNaseIII-like enzyme that is required for generating short interfering RNAs and microRNAs. The latter have been implicated in regulating cell fate determination in invertebrates and...

Overlapping Roles of CXCL13, Interleukin 7 Receptor α, and CCR7 Ligands in Lymph Node Development

Luther, Sanjiv A., Ansel, K. Mark, Cyster, Jason G.

Lymphoid tissue development is associated with local accumulation of CD4+ CD3− IL-7Rαhi hematopoietic cells that deliver lymphotoxin (LT)α1β2 signals to resident stromal cells. Previous studies...

In Vivo–Activated Cd4 T Cells Upregulate Cxc Chemokine Receptor 5 and Reprogram Their Response to Lymphoid Chemokines

Ansel, K. Mark, McHeyzer-Williams, Louise J., Ngo, Vu N., McHeyzer-Williams, Michael G., Cyster, Jason G.

Migration of antigen-activated CD4 T cells to B cell areas of lymphoid tissues is important for mounting T cell–dependent antibody responses. Here we show that CXC chemokine receptor (CXCR)5, the...