Wai, A, Horn, F., Mackson, J., Maxwell, D, McIntosh, K, Stanton, L, ...
The pathogenetic aspects of measles virus infection: Memorandum from a WHO meeting. (1994)
Billeter, M.A., Bellini, W., Van Binnendijk, R.S., Borrow, P., Fennelly, G., ...
Goulder, Philip J. R., Brander, C., Annamalai, K., Mngqundaniso, N., Govender, U., Tang, Y., ...
Cytotoxic T-lymphocyte (CTL) activity plays a central role in control of viral replication and in determining outcome in cases of human immunodeficiency virus type 1 (HIV-1) infection. Incorporation...
Feeney, M. E., Roosevelt, K. A., Tang, Y., Pfafferott, K. J., McIntosh, K., Burchett, S. K., ...
Advances in antiviral therapy have dramatically shifted the demographics of pediatric human immunodeficiency virus type 1 (HIV-1) infection in the developed world, and a growing proportion of...
Recovery in tracheal organ cultures of novel viruses from patients with respiratory disease.
McIntosh, K, Dees, J H, Becker, W B, Kapikian, A Z, Chanock, R M
Chen, S S, Lee, C N, Lee, W R, McIntosh, K, Lee, T H
The N-terminal region of the envelope (env) transmembrane protein of human immunodeficiency virus type 1 (HIV-1) has a leucine zipper-like motif. This highly conserved zipper motif, which consists of...
Sendai virus infection of mice with protein malnutrition.
Pena-Cruz, V, Reiss, C S, McIntosh, K
Sendai virus pneumonia was produced in BALB/c mice fed protein-deficient diets in an effort to understand the severity of viral pneumonia in infants in developing countries. Animals on the deficient...
Further characterization of the soluble form of the G glycoprotein of respiratory syncytial virus.
Hendricks, D A, McIntosh, K, Patterson, J L
A soluble form of the G glycoprotein, the attachment protein, of respiratory syncytial virus is shed from infected HEp-2 cells. The Gs proteins of the Long and 18537 strains have apparent molecular...
Hendry, R M, Pierik, L T, McIntosh, K
We compared washed nasal epithelial cells with unfractionated nasal secretions as sources of respiratory syncytial virus (RSV) antigens in an indirect enzyme-linked immunosorbent assay (ELISA). Of 28...
Cheeseman, S H, Pierik, L T, Leombruno, D, Spinos, K E, McIntosh, K
A commercially-available direct immunofluorescence (IF) reagent (Imagen; Boots-Celltech, Slough, Berkshire, United Kingdom) was similar in sensitivity and specificity to the conventional indirect IF...
Anderson, L J, Godfrey, E, McIntosh, K, Hierholzer, J C
To develop and evaluate an enzyme-linked immunosorbent assay (ELISA) for detecting adenovirus antigens in which a group-specific monoclonal antibody to the adenovirus hexon is used, we studied two...
An indirect enzyme-linked immunosorbent assay for detection of respiratory syncytial virus (RSV) antigens was developed, using commercially available antisera. Horse anti-RSV and calf antiserum to...
McIntosh, K, Hendry, R M, Fahnestock, M L, Pierik, L T
An enzyme-linked immunosorbent assay (ELISA) for respiratory syncytial virus antigens was applied to the rapid diagnosis of acute infections in children and was compared with viral culture and...
Rapid subtyping of influenza A virus isolates by membrane fluorescence.
Fishaut, M, McIntosh, K, Meiklejohn, G
During the winter of 1977-1978 three influenza A virus serotypes (A/Vic/3/75, A/Texas/1/77 [both H3N2], and A/USSR/90/77 [H1N1]) circulated in Denver, offering us the opportunity to apply fluorescent...
Clark, J, Schley, C, Irvine, K, McIntosh, K
In a study of virus recovery from clinical specimens, cynomolgus monkey kidney cells demonstrated sensitivity equivalent or slightly superior to rhesus kidney cells for siolation of myxo- and...
Fishaut, M, Murphy, N, Yanagihara, R, McIntosh, K
Tissue culture cells infected with varicella-zoster, respiratory syncytial, para-influenza types 1, 2, and 3, and influenza A/Texas/1/77 and A/USSR/90/77 viruses were exposed to ultraviolet light and...
Khouri, Y F, McIntosh, K, Cavacini, L, Posner, M, Pagano, M, Tuomala, R, ...
Almost all childhood HIV-1 is now acquired through vertical transmission. Identifying factors that affect the rate of transmission may lead to the initiation of specific preventive strategies. In...
McIntosh, K, McQuillin, J, Gardner, P S
Twenty-two infants under 9 months of age hospitalized with bronchiolitis or pneumonia due to respiratory syncytial virus (RSV) were serially sampled to determine the pattern of secretory antibody...
Feeney, M. E., Tang, Y., Roosevelt, K. A., Leslie, A. J., McIntosh, K., Karthas, N., ...
The emergence of cytotoxic T-lymphocyte (CTL) escape mutations in human immunodeficiency virus type 1 (HIV-1) proteins has been anecdotally associated with progression to AIDS, but it has been...
Secretory immunological response in infants and children to parainfluenza virus types 1 and 2.
The secretory immunological responses to natural infection with parainfluenza viruses ae not well defined. Nasopharyngeal secretion specimens from 20 infants and children naturally infected with...
Goulder, Philip J. R., Brander, C., Annamalai, K., Mngqundaniso, N., Govender, U., Tang, Y., ...
Cytotoxic T-lymphocyte (CTL) activity plays a central role in control of viral replication and in determining outcome in cases of human immunodeficiency virus type 1 (HIV-1) infection. Incorporation...
Feeney, M. E., Roosevelt, K. A., Tang, Y., Pfafferott, K. J., McIntosh, K., Burchett, S. K., ...
Advances in antiviral therapy have dramatically shifted the demographics of pediatric human immunodeficiency virus type 1 (HIV-1) infection in the developed world, and a growing proportion of...
Recovery in tracheal organ cultures of novel viruses from patients with respiratory disease.
McIntosh, K, Dees, J H, Becker, W B, Kapikian, A Z, Chanock, R M
Chen, S S, Lee, C N, Lee, W R, McIntosh, K, Lee, T H
The N-terminal region of the envelope (env) transmembrane protein of human immunodeficiency virus type 1 (HIV-1) has a leucine zipper-like motif. This highly conserved zipper motif, which consists of...
Sendai virus infection of mice with protein malnutrition.
Pena-Cruz, V, Reiss, C S, McIntosh, K
Sendai virus pneumonia was produced in BALB/c mice fed protein-deficient diets in an effort to understand the severity of viral pneumonia in infants in developing countries. Animals on the deficient...
Further characterization of the soluble form of the G glycoprotein of respiratory syncytial virus.
Hendricks, D A, McIntosh, K, Patterson, J L
A soluble form of the G glycoprotein, the attachment protein, of respiratory syncytial virus is shed from infected HEp-2 cells. The Gs proteins of the Long and 18537 strains have apparent molecular...
Hendry, R M, Pierik, L T, McIntosh, K
We compared washed nasal epithelial cells with unfractionated nasal secretions as sources of respiratory syncytial virus (RSV) antigens in an indirect enzyme-linked immunosorbent assay (ELISA). Of 28...
Cheeseman, S H, Pierik, L T, Leombruno, D, Spinos, K E, McIntosh, K
A commercially-available direct immunofluorescence (IF) reagent (Imagen; Boots-Celltech, Slough, Berkshire, United Kingdom) was similar in sensitivity and specificity to the conventional indirect IF...
Anderson, L J, Godfrey, E, McIntosh, K, Hierholzer, J C
To develop and evaluate an enzyme-linked immunosorbent assay (ELISA) for detecting adenovirus antigens in which a group-specific monoclonal antibody to the adenovirus hexon is used, we studied two...
An indirect enzyme-linked immunosorbent assay for detection of respiratory syncytial virus (RSV) antigens was developed, using commercially available antisera. Horse anti-RSV and calf antiserum to...
McIntosh, K, Hendry, R M, Fahnestock, M L, Pierik, L T
An enzyme-linked immunosorbent assay (ELISA) for respiratory syncytial virus antigens was applied to the rapid diagnosis of acute infections in children and was compared with viral culture and...
Rapid subtyping of influenza A virus isolates by membrane fluorescence.
Fishaut, M, McIntosh, K, Meiklejohn, G
During the winter of 1977-1978 three influenza A virus serotypes (A/Vic/3/75, A/Texas/1/77 [both H3N2], and A/USSR/90/77 [H1N1]) circulated in Denver, offering us the opportunity to apply fluorescent...
Clark, J, Schley, C, Irvine, K, McIntosh, K
In a study of virus recovery from clinical specimens, cynomolgus monkey kidney cells demonstrated sensitivity equivalent or slightly superior to rhesus kidney cells for siolation of myxo- and...
Fishaut, M, Murphy, N, Yanagihara, R, McIntosh, K
Tissue culture cells infected with varicella-zoster, respiratory syncytial, para-influenza types 1, 2, and 3, and influenza A/Texas/1/77 and A/USSR/90/77 viruses were exposed to ultraviolet light and...
Khouri, Y F, McIntosh, K, Cavacini, L, Posner, M, Pagano, M, Tuomala, R, ...
Almost all childhood HIV-1 is now acquired through vertical transmission. Identifying factors that affect the rate of transmission may lead to the initiation of specific preventive strategies. In...
McIntosh, K, McQuillin, J, Gardner, P S
Twenty-two infants under 9 months of age hospitalized with bronchiolitis or pneumonia due to respiratory syncytial virus (RSV) were serially sampled to determine the pattern of secretory antibody...
Feeney, M. E., Tang, Y., Roosevelt, K. A., Leslie, A. J., McIntosh, K., Karthas, N., ...
The emergence of cytotoxic T-lymphocyte (CTL) escape mutations in human immunodeficiency virus type 1 (HIV-1) proteins has been anecdotally associated with progression to AIDS, but it has been...
Secretory immunological response in infants and children to parainfluenza virus types 1 and 2.
The secretory immunological responses to natural infection with parainfluenza viruses ae not well defined. Nasopharyngeal secretion specimens from 20 infants and children naturally infected with...
Cranage, M P, Gardner, P S, McIntosh, K
Respiratory syncytial (RS) virus causes a local infection of the respiratory tract which is frequently severe in infants. We report the development in infected infants of antibodies in respiratory...
The prenatal exclusion test for Huntington's disease: experience in the west of Scotland, 1986-1993.
Tolmie, J L, Davidson, H R, May, H M, McIntosh, K, Paterson, J S, Smith, B
Information about the prenatal exclusion test for Huntington's disease (HD) has been given to an unselected series of couples who attended the genetic counselling clinic from 1986 onwards. Ten...